Research Contributions

Papers

8. Popovic A.*, Cao E.Y., Han J., Nursimulu N., Alves-Ferreira E.V.C., Burrows K., Kennard A., Alsmadi N., Grigg M.E., Mortha A. and Parkinson J. (2024) Commensal protist Tritrichomonas musculus exhibits a dynamic life cycle that induces extensive remodeling of the gut microbiota. The ISME Journal. 18(1): wrae023.
7. Taj B.*, Adeolu M.*, Xiong X., Nursimulu N., Ang J. and Parkinson J. (2023) MetaPro: A scalable and reproducible data processing and analysis pipeline for metatrascriptomic investigation of microbial communities. Microbiome. 11(1): 143.
6. Nursimulu N.*, Moses A.M. and Parkinson J. (2022) Architect: A tool for aiding the reconstruction of high-quality metabolic models through improved enzyme annotation. PLoS Computational Biology. 18(9): e1010452.
5. Curran D.M.*, Grote A.*, Nursimulu N., Geber, A., Voronin, D., Jones, D.R., Ghedin, E. and Parkinson, J. (2020) Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets. eLife. 9:e51850. eLife news release
4. Nursimulu N.*, Xu L.Y.*, Wasmuth J.D., Krukov I. and Parkinson J. (2018) Improved enzyme annotation with EC-specific cutoffs using DETECT v2. Bioinformatics. 34(19): 3393-3395.
3. Cotton J.A.*, Bennuru S., Grote A., Harsha B., Tracey A., Beech R., Doyle S.R., Dunn M., Hotopp J.C., Holroyd N., Kikuchi T., Lambert O., Mhashilkar A., Mutowo P., Nursimulu N., Ribeiro J.M., Rogers M.B., Stanley E., Swapna L.S., Tsai I.J., Unnasch T.R., Voronin D., Parkinson J., Nutman T.B., Ghedin E., Berriman M., Lustigman S. (2016) The genome of Onchocerca volvulus, agent of river blindness. Nature Microbiology. 2:16216.
2. Blazejewski T.*, Nursimulu N., Pszenny V., Dangoudoubiyam S., Namasivayam S., Chiasson M.A., Chessman K., Tonkin M., Swapna L.S., Hung S.S., Bridgers J., Ricklefs S.M., Boulanger M.J., Dubey J.P., Porcella S.F., Kissinger J.C., Howe D.K., Grigg M.E. and Parkinson J. (2015) Systems based analysis of the Sarcocystis neurona genome identifies pathways that contribute to a heteroxenous life cycle. mBio. 6(1). pii: e02445-14.
1. Song C.*, Chiasson M.A., Nursimulu N., Hung S.S., Wasmuth J., Grigg M.E., and Parkinson J. (2013) Metabolic reconstruction identifies strain-specific regulation of virulence in Toxoplasma gondii. Molecular Systems Biology. 9: 708.