Co-authored 31 patents/disclosures, including: US 0224313 A1 (Compositions and methods for classifying lung cancer and prognosing lung cancer survival); US 8,211,643 B2 (Prognostic and predictive gene signature for non-small cell lung cancer and adjuvant chemotherapy); US 8,026,055 (A minimal set of prognostic marker genes for early stage Non-small cell lung cancer - Materials and Methods for Prognosing Lung Cancer - 3-gene classifier); US-8434085 (Scalable Scheduling of Tasks in Heterogeneous Systems); US 6,339,776 B2 (Dynamic semi-structured repository for mining software and software-related information), as well as Canadian Patent 2,284,949, US8,211,643, JP5583117, EP2288741 (DE), EP2288741 (FR), EP2288741 (UK), US8,026,055.
Patents & Disclosures
Title: CDX2 as a biomarker to guide use of autophagy inhibitors in ovarian cancer
US62/952,724; Application Date: Dec 23, 2019
Joint Holder Names: Andrea Jurisicova; Igor Jurisica
Title: Cdx2 overexpression associated with decreased survival and poor prognosis of the patients with serous OEC
TDC Reference No. WS 2019-040; Application Date: March 31, 2019
Joint Holder Names: Andrea Jurisicova; Igor Jurisica
Title: Integration, visualization and analysis of human interactome
Joint Holder Names: Pastrello, C, Pasini, E., Jurisica, I.
Title: Computationally repurposing drugs for lung cancer: Candidate therapeutics from an integrative meta-analysis of cancer gene signatures and chemogenomic data
Joint Holder Names: Fortney, K., Kotlyar, M., Jurisica, I.
Title: Comprehensive In Silico prediction of physical protein interactions and characterization of interactome orphans
Joint Holder Names: Kotlyar, M., Jurisica, I.
Title: Systematically characterizing human proteins without reported interactions
Track Code: 2013-018
Joint Holder Names: Kotlyar, M., Jurisica, I.
Title: Construction of new medicines via game proof search
Track Code: 2013-019
Joint Holder Names: Heifets, A., Jurisica, I.
Title: Protein interaction and gene association prediction: Filling the gap with integrative approach
Track Code: 2013-020
Joint Holder Names: Vafaee, F., Jurisica, I.
Title: In silico drug screen in mouse liver identifiescandidate calorie restriction mimetics
Track Code: 2013-021
Joint Holder Names: Fortney, K, Kotlyar, M., Jurisica, I.
Title: NetwoRx: connecting drugs to networks and phenotypes in Saccharomyces cerevisiae
Track Code: 2013-022
Joint Holder Names: Fortney, Jurisica, I.
Title: Novel prognostic markers in mantle cell lymphoma.
March 2012.
Joint Holder Names: Goswami, R., L. Waldron, Jurisica, I., M. Crump, S. K. Reid
Title: SCRIPDB: a portal for easy access to syntheses, chemicals and reactions in patents. 2012-006, January 2012.
Joint Holder Names: Abraham Heifets, I. Jurisica
Title: A prognostic signature that predicts aggressiveness in B-cell non-Hodgkin lymphoma. 2010-051, August, 2010
Joint Holder Names: Goswami, R., L. Waldron, M. Crump, Jurisica, I., S. K. Reid.
Title: 14-gene prognostic signature for ovarian cancer.
March 2010
Joint Holder Names: Jurisica, I., L. Waldron.
Title: A robust 4-gene prognostic signature for oral squamous cell carcinoma
TDC reference number: 2010-016-02. March, 2010. Application filed 2012-Jan-11. Expiry 2013-July-11
Joint Holder Names: Jurisica, I., L. Waldron, P. Reis, S. K. Reid.
Title: LSC and HSC signatures for predicting survival of patients having hematological cancer.
December 3, 2010 US13/513,268; US20120237488A1
US Provisional Patent #61/266,704, TDC reference number: 2009-114-01. Filed Dec. 4, 2009
Joint Holder Names: Dick, J.; I. Jurisica; M. Minden; K. Eppert; E. Lechman; L. D. Waldron; B. Nilsson; B. L. Ebert; J. S. Danska; K. Takenaka.
Title: Compositions and methods for classifying lung cancer and prognosing lung cancer survival.
June 5, 2009; July 2008 PCT/CA2009/000774; WO02009146545, TDC #2007-020-02. USP 61-059085.
September 15 2011 US 2011/0224313 A1
Joint Holder Names: Zhu, C.Q., Jurisica, I., Aviel-Ronen, S., Coe, B., Lam, W., Tsao, M.-S., D. Der, S.
Title: Methods and compositions for lung cancer prognosis.
October 29, 2010. US61-171687, TDC# 2009-043-02, Filed 2009-04-21. PTC filed on 2010-04-21; TDC# 2009-043-03. WO 2010/121380A1
Joint Holder Names: Tsao, M.-S., Craddock, K., Lam, W., Buys, T., Jurisica, I., Shepherd, F.A.
Title: Prognostic gene expression signature for squamous cell carcinoma of the lung.
October 28, 2010. US61170743, TDC # 2009-007-02. Filed 2009-04-20. PCT filed 2010-04-20; WO 2010/121370 A1
Joint Holder Names: Tsao, M.-S., Shepherd, F. A., Jurisica, I., Der, S.D., Zhu, C.Q.
Title:NAViGaTOR: A scalable tool for protein-protein interaction network analysis and visualization
Invention Disclosure, March 25, 2009. 2009-032
Joint Holder Names: D. Otasek, M. Ali, W. Xie, M. McGuffin, B. Devani, K. R. Brown, I. Jurisica.
Title: Prognostic and predictive gene signature for non-small cell lung cancer and adjuvant chemotherapy
July 22, 2010 US12/465,954; US12/684,370; PCT/CA2009/000650; WO0200913
July 3, 2012 US 8,211,643 B2; US 20090291448
Joint Holder Names: M.-S. Tsao, F. A. Shepherd, I. Jurisica, S. D. Der, C. Q. Zhu, D. Strumpf, L. Seymour, K. Ding.
Title: A 12-gene prognostic gene signature for squamous cell carcinoma of lung.
January 2009.
PCT/CA2010
Joint Holder Names: M.-S. Tsao, C.-Q. Zhu, I. Jurisica, S. D. Der, F. A. Shepherd.
June 10, 2010 Title: Methods for biomarker identification and biomarker for non-small cell lung cancer.
US61119936, TDC #2008-024-01, December 4, 2008. PCT/CA2009/001775 filed on 2 December 2009; WO 2010/063121 A1
Joint Holder Names: M.-S. Tsao, P. C. Boutros, S. Lau, F. A. Shepherd, L. Z. Penn, I. Jurisica, S. D. Der.
Title: A method to find all prognostic signatures from a microarray dataset.
Invention Disclosure. July 2008.
Joint Holder Names: P. C. Boutros, S. Lau, F. A. Shepherd, S. D. Der, M.-S. Tsao, L. Z. Penn, I. Jurisica
Title: 2048 Novel Six-Gene Prognostic Markers for Non-Small Cell Lung Cancer.
Invention Disclosure. July 2008.
Joint Holder Names: P. C. Boutros, S. K. Lau, F. A. Shepherd, S. D. Der, M.-S. Tsao, L. Z. Penn, I. Jurisica.
Title: Gene markers of invasive cancer in lung bronchiole-alveolar carcinoma.
IPD 2007-020-02.INV 08-011, US61/059,085, B&P 10723-271, filed June 5, 2008.
Joint Holder Names: M.-S. Tsao, S. A.-Ronen, I. Jurisica, C.-Q. Zhu, W. Lam, B. P. Coe.
Title: A 15-gene prognostic signature for non-small cell lung cancer.
June 2008.
Joint Holder Names: M.-S. Tsao, F. A. Shepherd, I. Jurisica, C.-Q. Zhu, D. Strumpf, K. Ding, L. Seymour.
Title: Interologous interaction database
Invention Disclosure, June 18, 2007. 2007-034
Joint Holder Names: K. R. Brown and I. Jurisica.
May 22, 2007 Title: Detection of ovarian cancer biomarkers by proteomics and bioinformatics
US Provisional Patent 60/929, 861
Joint Holder Names: T. Kislinger and I. Jurisica.
Title: A minimal set of prognostic marker genes for early stage Non-small cell lung cancer - Materials and Methods for Prognosing Lung Cancer - 6-gene classifier
2007
Joint Holder Names: M. Sound-Tsao, S. Der, P. Boutros, S. Lau, M. Pintilie, F. Shepherd, I. Jurisica.
September 27, 2011 Title: A minimal set of prognostic marker genes for early stage Non-small cell lung cancer - Materials and Methods for Prognosing Lung Cancer - 3-gene classifier
US 11/940,707, 2007. Patent No: US8026055B2, US20080176236, Sept 27, 2011
Joint Holder Names: M. Sound-Tsao, S. Der, P. Boutros, S. Lau, M. Pintilie, F. Shepherd, I. Jurisica, L. Penn.
Nov 12, 2009 Title: Scalable Scheduling of Tasks in Heterogeneous Systems.
IBM Invention Disclosure, IP&L Disclosure Evaluation: CA8-2007-0054, 2007. Patent filed February 21, 2008; CA9-2008-0019. US2009/0282413 A1, November 12, 2009
Joint Holder Names: E. Xia., I. Jurisica, J. Waterhouse, E. Cialini.
April 30, 2013 US-8434085
Title: Dynamic selection of scheduling heuristics in heterogeneous systems.
IBM Invention Disclosure, 2006.
Joint Holder Names: E. Xia, I. Jurisica, J. Waterhouse, V. Sloan.
Title: Run time estimation using TA3 case-based reasoning system for scheduling in a grid
environment.
IBM Invention Disclosure, http://www.priorartdatabase.com/IPCOM//000148769D, 2006.
Joint Holder Names: E. Xia, I. Jurisica, J. Waterhouse, V. Sloan.
Title: Potential new markers for colorectal cancer diagnosis and targeting.
Invention Disclosure, 2005.
Joint Holder Names: M. Sound-Tsao, I. Jurisica, I. Seiden-Long, K. Brown.
Title: Dynamic semi-structured repository for mining software and software-related information.
January 15, 2002 US Patent US 6,339,776 B2, January 15, 2002;
October 14, 2003 Canadian Patent 2,284,949, October 14, 2003.
Joint Holder Names: H. Dayani-Fard, I. Jurisica.
All contents copyright Jurisica Lab, Krembil Research Institute, UHN. Last modified February 2019