NSERC: Novel methods for integrative computational biology
PI: I. Jurisica 2018-2023
Genome Canada: Interactome mapping of disease-related proteins using split intein-mediated protein ligation (SIMPL)
PI: I. Stagljar, I. Jurisica, T. Kislinger 2018-2021
Ontario Research Fund: The Next Generation Signalling Biology Platform
PI: I. Jurisica 2018-2021
Ontario Research Fund: Protein network analysis of cancer surfaceome - from interactions to drugs
PI: I. Stagljar and I. Jurisica 2016-2020
CCSRI: A novel model of human brain metastasis from lung cancer: Discovering genes that regulate brain metastasis
PI: Sheila Singh 2016-2019
Medicine by Design: Pathways to enhance the clinical utility of hematopoietic stem cell transplantation
PI: J. Dick 2016-2019
Genome Canada: The Mammalian Membrane Two-Hybrid (MaMTH) Assay - an Advanced Proteomics Technology for Biomedical Research
PI: I. Stagljar and I. Jurisica 2016-2019
Past Funding
Krembil Foundation: The Osteoarthritis Data Integration Platform (OADIP): Identifying and mapping genomic markers of osteoarthritis
PI: I. Jurisica and C. Veillette 2016-2018
NSERC: Developing novel heuristic methods for integrative computational biology
PI: I. Jurisica 2013-2018
DOD: Optimizing Early-Phase Translational Ovarian Cancer Clinical Trials with Integrative Computational Biology
PI: A. Oza and I. Jurisica 2012-2017
CRC-CFI: Integrative cancer informatics
PI: I. Jurisica 2011-2018
McLaughlin Centre: Development of hybrid modeling approaches for identifying multicomponent targeted therapies
PI: I. Jurisica 2014/15
ORF-GL2: Cancer Gene Encyclopedia (CGEP): Computationally optimized characterization of cancer genes, proteins, their structure, function and interactions.
PI: I. Jurisica, G. Bader, Co-applicants: L. Stein, Q. Morris 2010-2015
NIH: Growth Factor Receptor Signaling in Breast Cancer
PI: MC Hung 2010-2015
ORF-RE: Integrated Molecular Pathology of Targeted Cancer Therapy in Lung Cancer (IMP4-Lung Cancer)
PI: M. Tsao, I. Jurisica, Co-applicants: F. Shepherd, G. Liu, T. Kislinger, M. Moran April 2009-2015
CIHR: Diagnostic and prognostic biomarkers for epithelial ovarian cancer
PI: I. Jurisica, A. Oza, Co-applicants: T. Kislinger, T. Colgan, A. Jurisicova June 2009-2014
NIH: Development of an expert crystallization knowledge system
PI: E Snell 2009-2014
McLaughlin Centre: Cancer prevention and treatment by molecular epidemiology
PI: I. Jurisica 2013/14
CIHR: The interactome of the human G-protein coupled receptors
PI: I. Stagljar, Co-applicants: Bouvier, Michel, Jurisica, Igor 2011-2013
NSERC: Techna 2012: Information and Communication Technologies for Health
PI: I. Jurisica 2012
NSERC: Scalable intelligent systems for integrative analyses in computational biology
PI: I. Jurisica 2012-2013
CFI LOF: Integrative computational biology for cancer genomics
CIHR Catalyst grant: Tools for efficient and effective network-based prediction of diagnostic and prognostic cancer signatures
PI: I. Jurisica, Co-applicants. Drs. M.S.Tsao and I. Stagljar November 1, 2009-October 31, 2010
CIHR: Maternal lethal effect and human infertility
PI: A. Jurisicova, Co-applicants: I. Jurisica, E. Greenblat July 2007-July 2010
Canada Foundation for Innovation/Ontario Research Fund: Comprehensive Systems Biology Approach to Profiling and Modeling of Cancer. A collaborative infrastructure for integrated translational research.
PI: I. Jurisica, Principal users: Attisano, L., Bremner, R., Brown, T., Jurisica, I., Kislinger, T., Penn, L., Rottapel, R., Shaw, P., Tsao, M., Wrana, J. 2007
Canada Foundation for Innovation CRC/CFI/ORF Infrastructure - Integrative Computational Biology
PI: I. Jurisica November 1, 2006 - October 31, 2011
NIH - the Center for High Throughput Structural Biology (U54 GM074899-01)
PI: G. DeTitta, Co-PIs: Mark Dumont, Mark Sullivan, Eric Phizicky, Ethan Merritt, Sol Gruner, Igor Jurisica, Mike Soltis, Mike Malkowski, Joe &nb sp; Luft, Eddie Snell, Keith Hodgson. July 1, 2005-2010
Genome Canada - The Dynactome: Mapping Spatio-Temporal Dynamic Systems in Humans
PI: T. Pawson, J. Wrana, S. Li, I. Jurisica, J. Dennis January, 2006 - 2009
OICR: Identification and characterization of genetic alterations at the stromal-epithelial interface in prostate cancer.
PI: N. Fleshner; coPIs, T. Brown, S. Done, I. Jurisica, J. Sweet May 2007-2010
NSERC Strategic Grant: Intelligent monitoring, diagnosis, and rehabilitation of stroke patients.
PI: J. Glasgow, I. Jurisica, S. Scott October 2006-2009
CIHR - Defining the canonical and non-canonical WNT signaling pathways
PI: Attisano; I. Jurisica July, 2005-2008
CIHR - Endoglin, ALK-1 and BMPRII networks: Role in vascular disorders
PI: M. Letarte; I. Jurisica; J. Wrana July, 2005-2010
CIHR - Myometrial programming: A new concept underlying the control of myometrial contractility during pregnancy
PI: S. Lye; I. Jurisica; B. Langille July, 2005-2010
CIHR - Functional characterization of androgen-altered genes with a putative role during early events in ovarian carcinogenesis.
PI: T. Brown, Co-PIs: I. Jurisica, P. Shaw, M. Letarte June 2005 - June 2009
CIHR - The next generation of gene transfer therapy for human nasopharyngeal cancer.
PI: Fei-Fei Liu, Co-PIs: I. Jurisica, R. M. Reilly 2004-2008
National Cancer Institute of Canada - Novel Molecular Prognostic Markers and Potential Therapeutic Targets in Non-Small Cell Lung Cancer (# 015184)
PI: M-S Tsao; Co-PIs: I. Jurisica, W. Lam, M. Johndston, S. Der (UT), M. Pintilie, D. Wigle, F. Shepherd; Additional authors: C.-Q. Zhu, B.P. Coe, J. Liu 2003-2008
DOD US Army - Integrated computational biology approach to marker selection for early detection and treatment of epithelial ovarian cancer. # OC040038
PI: I. Jurisica, Co-applicants: T. Brown, A. Oza, P. Shaw, J. Wrana November 15, 2004- November 15, 2007.
NSERC Research Grant - Decision Support for Biomedical Domains
I. Jurisica April 2002- March 2007
Ontario Cancer Research Network - Genomic and proteomic biomarkers of response to treatment with small molecule epidermal growth factor receptor inhibitors in non-small cell lung cancer; OCRN 03-APR-0324
PI: M-S Tsao, Co-PIs: I. Jurisica, F. Blackhall, W. Newman, F. Shepherd, L. K. Seymour, M. Pintilie September 2003- September 2006
NIH - Northeast Structural Genomics Consortium 2- Structural Genomics of Eukaryotic Model Organisms
PI: Gaetano Montelione, Co-PIs: Arrowsmith, Cheryl, Anderson, DeTitta, George, Edwards, Aled, Gerstein, Mark, Hendrickson, Wayne, Honig, Barry, Hunt, John, Jurisica, Igor, Kennedy, Michael A, Regan, Lynne, Rost, Burkhard, Szyperski, Thomas, Tong, Liang July 1, 2005- July 1, 2006
GlaxoSmithKline – An integrated computational approach to identify important yeast proteins
PI: I. Jurisica November 1, 2004-2005
IBM SUR grant – Life Sciences Discovery Centre
PI: I. Jurisica May 2005
IRIS - Intelligent Computational Methods for the Analysis of Gene Expression Profiles
PI: I. Jurisica, Co-PIs: J. Glasgow, R. Ng, H. Hoos 1/2002-2005
NIH - Northeast Structural Genomics Consortium - Structural Genomics of Eukaryotic Model Organisms
PI: Gaetano Montelione, Co-PIs: Arrowsmith, Cheryl, Anderson, DeTitta, George, Edwards, Aled, Gerstein, Mark, Hendrickson, Wayne, Honig, Barry, Hunt, John, Jurisica, Igor, Kennedy, Michael A, Regan, Lynne, Rost, Burkhard, Szyperski, Thomas, Tong, Liang October 1, 2000 - August 31, 2005
IBM SUR Grant - Integrated computational biology
PI: I. Jurisica 5/2003
NSERC Strategic Grant - Knowledge Management and Decision Support for Crystal Growth
J. Glasgow, I. Jurisica, S. Fortier, Industry collaborators: Evan Steeg of Molecular Mining Corporation; IBM Canada, Centre for Advanced Studies 1999-2003
IBM UPP Grant - Data mining, visualization and interpretation of high-throughput biological data
PI: I. Jurisica 9/2002
IBM UPP Grant - Knowledge Management in Biological Domains
PI: I. Jurisica 9/2001
IBM UPP Grant - Protein Crystallization Knowledge Management
PI: I. Jurisica 9/2000
IBM SUR Grant - Decision-Support System for Crystallization Experiment Design
PI: I. Jurisica 12/1999
NSERC Research Grant - Decision Support for Biomedical Domains
PI: I. Jurisica 3/1998-3/2002
NSERC Equipment Grant - Molecular Scene Analysis and Macromolecular Crystallization
J. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto April 2000
CITO Research Grant - Knowledge Discovery for Crystal Growth
J. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto April 1 2000 - March 31 2002
NSERC Equipment Grant - Computational Techniques for Bioinformatics
J. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto
CITO Research Grant - CBR: Knowledge Management and Applications
J. Glasgow, S. Fortier - Queen's U, N. Cercone - U Waterloo, S. Matwin, R. Holte - Uof Ottawa, I. Jurisica - U of Toronto April 1 1998 - March 31 2000
All contents copyright Jurisica Lab, Krembil Research Institute, UHN. Last modified February 2018