Adenocarcinoma_PMID16549822 Adenocarcinoma_PMID18927117 Adenocarcinoma_PMID18992152 Adenocarcinoma_PMID12118244 Adenocarcinoma_PMID11707567 Carcinoid_PMID11707567 SmallCell_PMID11707567 Squamous_PMID11707567 LargeCell_PMID11707590 Adenocarcinoma_PMID11707590 SmallCell_PMID11707590 Squamous_PMID11707590 LargeCell_PMID20421987 Adenocarcinoma_PMID20421987 Squamous_PMID20421987 Adenocarcinoma_PMID18297132 Adenocarcinoma_PMID16314486 Adenocarcinoma_PMID17540040 Squamous_PMID15833835 Squamous_PMID16188928 Squamous_PMID14581339 metformin -0.161347212549322 0.0558092410768063 0.227111044233113 0.0388562992681139 0.0613066236947439 -0.119506974143006 0.0667395852485396 0.092027548545452 0.118599823710543 0.118261619354273 0.13614934805394 0.0508477980669186 0.117018487363615 0.0851740201259119 0.153335338482696 -0.0102641001023627 0.0544885004317908 0.124057044358874 0.132651705259143 -0.0203178095003215 0.0859364531654814 phenformin -0.374118360167131 -0.132633980920799 0.149065141841365 -0.114112665028769 -0.2022657142455 -0.0786767953134514 -0.229062234652236 -0.315901547538721 0.00101042947850847 -0.225165355241669 -0.141494255237896 -0.252455070738506 -0.256849555682464 -0.274853580917721 -0.207581131894284 -0.191721561980033 -0.154884798936671 -0.188994060915417 -0.0975006359503904 -0.234353877748566 -0.16672475183452 phenyl biguanide 0 0.499071694877848 0 0.598479846992279 0.516592712445921 0 0 0 0.294535134678587 0 0 0 0.480017428867408 0.446880438094662 0 0.485960846798238 0.455450795086284 0.46529991726907 0.612978711493967 0 0.588076154362774 valproic acid -0.176649152999589 -0.193088241629112 0.108262474479355 -0.300202859717895 -0.260113656479646 0.263068865578709 -0.237869579401097 -0.246558168288697 -0.218767993314435 -0.32985270237229 -0.204580292088891 -0.291643398874431 -0.178812259761471 -0.209816655582975 -0.257185333397686 -0.281605020180719 -0.357031680729713 -0.253445063455569 -0.269271537753663 -0.317948272956607 -0.212574649759628 estradiol 0.228405040256749 0.130720568299345 -0.0457196294497289 0.0751564404205907 0.183756941152389 0.0703134419702133 0.162685787016593 0.0907396463513318 0.128139198740685 0.0944880561344527 0.152658962638707 0.146221741043052 0.141985185735732 0.133798700174613 0.0714616825765705 0.155490475229011 0.198808700285913 0.104292403766679 0.0470441070856797 0.0607915300919979 0.195439885457645 alpha-estradiol -0.0169337755631882 -0.546389309359714 0.00823811018492214 -0.419369878513205 -0.478499169724379 -0.102134105681234 -0.135772415395057 -0.483721523267507 -0.401823488157823 -0.601589272326112 -0.308638220722829 -0.455519779456521 -0.495207302952717 -0.590663448599373 -0.529264070986951 -0.557208944411702 -0.300315584180789 -0.525968435534768 -0.594060138904687 -0.219242085306158 -0.489857177258314 dexamethasone -0.195119933900512 -0.0642915926046799 0.0551876011441639 0.0477903015009384 0.00127719777419143 -0.101057245225482 -0.271832691573221 -0.120103114002227 -0.0211670341874042 -0.0114493464004941 -0.105358611216146 -0.0862529904756133 -0.0531555658005738 -0.0195738937205679 0.046157985176371 0.0059914935900357 0.0208235693379425 -0.0831648021804697 -0.0466420095835618 -0.143131119148364 -0.0840718467167728 mesalazine 0.237052762548319 0.0648955187548612 -0.0239923585732893 -0.0396495203918265 0.102899710303826 0.0957901382427713 -0.0875587259767888 0.0972838349323101 -0.0185413244007782 -0.0230952063855081 -0.0678172549359919 0.042497455224307 0.0683227364620941 0.0492914726944111 0.0265555350141531 0.054431826370041 -0.0746076170508223 -0.0265214956474477 -0.207082485931677 -0.134516539618681 -0.044927177030948 chlorpropamide -0.0316953836134016 -0.197749633487608 0.159685914863332 -0.0168759671607541 -0.0925445281913672 -0.169045660302278 -0.165348838970158 -0.155123886017983 -0.141659600129977 -0.113738630091165 -0.0978274625958913 -0.162727881413063 -0.183499995035686 -0.197133533420785 -0.170632416707353 -0.152033987296736 -0.0149207571532763 -0.0762486927650803 -0.00825354994737393 -0.00927337222121801 -0.296536231613577 tolbutamide -0.150562540674189 -0.0912023284851965 0.0735075807250263 -0.00252386159861364 -0.087558665374041 -0.0889787579999011 -0.0618708570888918 -0.173753428242384 -0.0247609547471824 -0.109513593534232 -0.143761345446734 -0.0870582473511877 -0.0904425522186739 -0.128972114924727 -0.11406058961378 -0.0766231008087963 0.028717264010142 -0.0993672181190472 -0.178798394211077 0.0665004717077343 0.016584408945416 tamoxifen -0.342212763363527 -0.172836998270864 0.112647473158056 -0.234458154665544 -0.0975349421090349 -0.0848484980921132 -0.287984102552271 -0.178578831006603 -0.312584715041951 -0.283250600333372 -0.332855930839156 -0.269576720440873 -0.280054681258206 -0.215832708361572 -0.245255369044543 -0.202391161607004 -0.219633834771551 -0.381313376786783 -0.0557961342258064 -0.120895806349758 -0.233358969559566 verapamil -0.0418159330233597 -0.157934963782633 -0.0278168571580392 0.09290110592016 -0.181080003982982 0.0259629798109805 -0.152986117186485 -0.126660547088554 -0.18908900695306 -0.138741399040488 -0.193636517945753 -0.205733287874065 -0.104910986642762 -0.11021036200167 -0.0679912988985212 -0.0499485109993584 -0.116700162914274 -0.112783690522078 -0.0399370280597587 -0.143258893111182 -0.210975878974982 dexverapamil 0 -0.91833762582576 0 -0.903889160509389 -0.856819322958782 0 0 -0.869413202295737 -0.69151456834741 -0.876372312052559 -0.620941605787211 -0.839644677331906 -0.841193627917081 -0.925107518816366 -0.883841789172061 -0.918707420519637 -0.807754855979545 -0.92556511168208 -1 -0.826055746141084 -0.730875919959163 exemestane -0.486456150596452 -0.639835206170056 0 -0.701908759570975 -0.637962878939042 0 -0.416869607778001 -0.636313740769183 -0.508853876005968 -0.728644611070173 -0.54517098533856 -0.633079021332914 -0.573425089067397 -0.670637473339226 -0.592316126153439 -0.647891981332559 -0.72622378053388 -0.674158545909288 -0.808557198918095 -0.657160626662166 -0.528531780268287 rofecoxib -0.210030870733591 -0.264493594241045 -0.20586537632705 -0.189535437501512 -0.165647489133882 -0.0639356539977163 -0.123243554137737 -0.120787283446554 -0.288676669826722 -0.257726769559183 -0.00437980280055278 -0.238676909243992 -0.165716581783644 -0.204697124884805 -0.210313416676326 -0.293922530274631 -0.165481651585571 -0.293113591443528 -0.294681967146141 -0.215224962971754 -0.0341375887715596 amitriptyline -0.152389889222269 0.240471987331363 -0.152715238892332 0.228672627712952 0.312197107116416 -0.228980397088629 -0.138547606385968 0.100016201578568 0.0415211154677133 0.095282821912508 -0.0958563037862207 0.175883688759596 0.265895199488796 0.33880973004789 0.00774878322602605 0.343307649614158 0.172791862942534 -0.0129794448235793 0.279011034050128 -0.115189763326359 0.28460334829871 sulindac -0.114787849594951 -0.0251859529115378 0.0536692028626027 0.115531391749758 -0.0341432239520671 0.0596681386657645 -0.106351501756532 0.0466742793042885 0.0500567407982592 0.0178570637171341 -0.0387920998890665 0.00649036307778168 0.00762549611433039 0.0528100351288316 -0.0120501632442586 -0.00456788907721358 0.0111087311807711 0.0187453730282103 -0.000772773069535953 0.169082438750838 -0.0980047348697433 tacrolimus 0 0.508063920018795 -0.278951155858315 0.568411229752657 0.49314042465377 0 0.043112154844584 0.237726928123236 0.359014088635787 0.477841258411291 0.026445957826939 0.51039981025763 0.516194760539839 0.55516559906362 0.235787486611712 0.506089199289604 0.380176417471679 0.204955450349451 0.612087883098445 0.30655945624341 0.56302346822673 15-delta prostaglandin J2 -0.437797892143876 -0.363857232601676 0.221266112410548 -0.145906104007485 -0.192856070355145 -0.0143275490637568 -0.274654347143672 -0.174262964898048 -0.100094253711103 -0.214632039920349 -0.350539703885504 -0.169270623982326 -0.238912798592628 -0.52415127862018 -0.429802217194272 -0.324022127397122 -0.307014643026447 -0.456079813767249 -0.384678977165512 -0.241755412308822 0.287590863566652 raloxifene -0.223224872812349 -0.0326973643904132 -0.0189597449954551 -0.0362411935702903 -0.123923978742877 0.0362380271928493 -0.211852277877376 -0.0844745162222133 -0.198717356182031 -0.048879657457342 -0.214404298896723 -0.13253635740692 -0.181475640648262 -0.0976052275848242 -0.0859055769319877 -0.19036710382893 -0.0822547975798093 -0.0701058389881351 -0.0732511893870778 -0.149666904520238 0.0264064126967775 nordihydroguaiaretic acid -0.135030612830272 -0.144198838524081 0.0743565701464292 -0.203397566851915 -0.307488473975604 -0.0777153804059814 -0.0481782986682954 -0.340792071433645 -0.166391966729084 -0.309379522180423 -0.205140963393848 -0.233536013559834 -0.288149908891018 -0.259354893966297 -0.339136853930343 -0.237468275974925 -0.180057161491459 -0.308070727677788 -0.382210484887575 -0.144837734458301 -0.158732754970313 sulfasalazine -0.189742264940034 -0.267756289214577 0.119272864294207 -0.0815038197891572 -0.296602095595866 -0.26624499188532 -0.360482891779363 -0.3472001610479 0.0021906090472141 -0.280718385955595 -0.12519586822193 -0.226394809428838 -0.356166660372263 -0.196256066037717 -0.161983370223744 -0.19620134013386 -0.104574985802738 -0.2125638771135 -0.277446266177101 -0.232353816493331 -0.287275183550214 celecoxib 0.0754211570405039 0.136739795601575 -0.273349736315397 0.0327027841792837 0.156218526218841 0.00488398610846009 -0.0643453241508162 0.116522571633239 0.127559204594894 0.065589538481397 0.161349409905371 -0.0134460627960021 0.149677452474587 0.0675054567067297 -0.128197104102935 0.0778582703432026 0.178173959909583 0.0377969772213428 0.170720944631611 0.10136462548508 0.0323775759910545 LM-1685 -0.388777576516637 -0.222626846754579 0.284498624110363 -0.264173521752787 -0.223231184980898 0 0 -0.289816485973129 -0.361553532140593 -0.299458294862482 -0.189161073591017 -0.244113606109477 -0.230247497188464 -0.251851672724686 -0.298732310331337 -0.236826198212539 -0.332306285322332 -0.405589772209013 -0.248210728333599 -0.50082200589202 -0.165521383863098 SC-58125 -0.121445036421709 -0.130557245221286 -0.134424554176849 -0.161120622459612 -0.0365387496638313 -0.146294420647006 0.0358791327663167 -0.0636415345995996 -0.197301876389052 -0.18385968063623 0.0117898212585576 -0.0923558156839413 0.015643170343626 -0.0349799737083546 -0.0414577522931043 -0.0811774989110613 -0.0637389919480823 -0.0799670653411833 -0.206323394267047 -0.189074088268701 0.130577072915896 tanespimycin -0.117598188390988 -0.323293781617164 0.146569006441868 -0.375801152687695 -0.209077122735376 0.00924626199593131 0.0170576538465793 -0.373956474817405 -0.305229664499167 -0.435510153214518 -0.31269580968258 -0.401575587380238 -0.398540405628478 -0.381620860346274 -0.469304362246561 -0.450959586609477 -0.338154331144511 -0.534905335747699 -0.479829934719664 -0.244074955896382 -0.251400861355164 tomelukast 0.611668398854043 0.460422612901515 0 0.497304556320757 0.583522088876461 0 0.509132258186463 0.527875083113578 0.449289144573084 0.465602956075961 0.32391106992441 0.438793168461415 0.506668002050283 0.516071343591461 0.459977326581825 0.629841931973564 0.382161753652199 0.538136966505658 0.410038495807524 0.541769099361074 0.537261214399237 TTNPB 0.312323086770664 0.194012341433683 -0.231072191177978 0.0609585401903482 0.419336510917649 0.140552128527889 -0.103313051453845 0.0558035931002968 0.267335626633175 0 -0.122790506695437 0.227541970646236 0.128789977956566 0.224027525220258 0.0652277642295565 0.367799696419657 0 0 0.125743323923736 -0.175027899946585 0 tretinoin 0.045831512747408 -0.379054122282569 0.24527851832168 -0.258136991530026 -0.423890525998636 -0.374563216881338 -0.16504915954192 -0.511248404412091 -0.315733546055774 -0.325532745075215 -0.285794729317612 -0.355392951803986 -0.485820727875108 -0.452437757815245 -0.458594474974101 -0.314719175387418 -0.0602873494630537 -0.377984583140856 -0.396831651550963 -0.24919538316411 -0.281626464151955 LY-294002 -0.289548460625725 -0.468813767683606 0.0793131436519725 -0.433597920410567 -0.361477364706333 0.0342128206529475 -0.208733550189115 -0.439679530258307 -0.334842275321211 -0.422463204924592 -0.283275354960895 -0.446143100285148 -0.429284989994681 -0.46150176232674 -0.422701139675595 -0.484913601341266 -0.531991953776832 -0.455442614576639 -0.470989709785628 -0.427149869052342 -0.493137965984365 ciclosporin 0.226886134360915 0.159787874530929 0.312123003661507 0.299044690727348 0.132462295436579 0.240952980697848 0.0907787244538771 -0.0662823904356724 0.0699220593181067 0.0961297468948007 -0.263423415674517 -0.0177305639219241 -0.0145912923768544 -0.0113453851218624 -0.133509204286405 0.218450845338625 0.315988258700962 0.117119778767924 -0.043486046985634 0.0690599347364546 0.0957175635184948 indometacin -0.0618121982021391 -0.34074769050548 0.125798330726601 -0.291694798756298 -0.333626288873451 -0.143862241091211 -0.245252717822978 -0.364880600356372 -0.284078710623991 -0.318432728051643 -0.232368584619023 -0.258350058748637 -0.320822115339091 -0.407034388159245 -0.330701075869226 -0.359182773441832 -0.251043972201518 -0.373450174861044 -0.238880885357108 -0.308676935840749 -0.393325881500422 clofibrate -0.295603303703208 -0.227423501396988 0.0655887389274057 -0.150339524635121 0.00913631259201458 0.00528322739353354 -0.120321909714695 -0.180223520281874 -0.295665570138433 -0.366063799154132 -0.253835874276144 -0.370437270477069 -0.224948228794269 -0.279023121797957 -0.248735019517001 -0.241061831960909 -0.182180725150337 -0.234066835508573 0.253679871765252 -0.190516229687983 0.228362413668846 MK-886 0.194823319281235 0.106854658125714 0 0.278386205523923 0.20359655798575 -0.186659091615323 -0.149119198985423 0.259612249979034 0 0.125025350499925 0 0.258276041522487 0.247349100956791 0.124521308401064 0.305962218808964 0.103684015339757 0.262820621275018 0.107454307496323 0.388775079960435 0.0884966067777563 0.158602479455055 prednisolone -0.3667442635898 -0.0856998383252013 0.285830921348685 -0.0388072244789974 -0.0831060036105624 -0.0992198174348995 -0.290769732655977 -0.0920899655949098 0.10391012078682 0.0297418068095034 0.0654757994962239 0.0133620971700436 -0.0878168813320363 -0.0949322192058333 -0.0625690773337119 -0.105217604258379 -0.172795094894762 -0.0939050618756671 -0.0889759956232708 -0.207303874472323 0.0554965030893172 thalidomide -0.0640901270805217 -0.441928010084007 0.0831742637192171 -0.269506927164914 -0.321309550136302 -0.290742228048231 -0.175365042960449 -0.372072198129525 -0.38924554620994 -0.2618437871328 -0.182226288252246 -0.392263127157168 -0.467805927772105 -0.425219999858625 -0.482565272728985 -0.455191970053033 -0.362028164768069 -0.42078225801025 -0.438644570800963 -0.274356278627901 -0.198582374891351 genistein 0.166007786197031 0.273645315541599 -0.300718967628417 0.174696581032459 0.21441293871109 0.0963755245431133 0.230846805193587 0.200818269657907 0.257235023087371 0.235662078749683 0.125325299554698 0.314072016213713 0.241008699395765 0.265671129275776 0.218313459277918 0.268529551671924 0.273690597249461 0.282777958256026 0.085448347222756 0.155204986248107 0.317356545396244 fludrocortisone 0.0118825536119369 0.522937324767056 -0.131060379183731 0.39474594316678 0.475785979743892 0.185670812886429 0.135961387406588 0.535975587046049 0.465037289892783 0.56717366624327 0.376433651043842 0.529964440509464 0.518181058309124 0.537805307786821 0.544123296437139 0.51265226730457 0.472457047079319 0.551805180855551 0.517827633970034 0.25132664365178 0.35199944860446 quercetin -0.217615958994801 -0.0218197719731015 0.0752600587681926 0.0194944596305164 -0.220802597059945 -0.346721145760824 -0.161420819943295 0.064860111591128 0.192900447654714 0.02737548268245 0.0675703568255578 -0.0277334293147396 -0.176602335024317 -0.265062450930081 -0.10866072185421 0.0367355679048098 0.121082703475095 -0.0419997985287909 0.0773295155683631 0.00894393985868031 0.122276322673817 sulindac sulfide 0 0 0 0 0 -0.60080093142239 0 0 0 0.529130006985621 -0.404010411237089 0.428748854578238 0.42907863663963 0.461680162011973 0 0.513052739019388 0.434173298081173 0.511573994877849 0.48162844341202 0.601810467907758 0.477202413203547 exisulind 0 0.105268882148864 -0.34581805097944 0.113300544581254 0 0.0212526659707389 0 0.252742823659842 0.21829265273975 0.221246880709012 -0.217666579153348 0.206907965723132 0.39767860254033 0.0844087305402528 -0.320898134300708 0.0693576267669141 0.0176836890852238 0.0824479626663348 0.13460932409838 0.307495218365302 0.263779639570397 fulvestrant -0.151443554660759 -0.116069080226153 0.0665356207612166 -0.216702429499369 -0.171297579502609 -0.0511684552371971 -0.135262972170882 -0.224131308231664 -0.0901156927184893 -0.138635494953611 -0.184379199043298 -0.137633762122521 -0.126037980256462 -0.142945059955164 -0.130625599063431 -0.145013006924057 -0.207659916799382 -0.14333266382882 -0.115442208125883 -0.143807285330438 -0.236887057764563 monastrol -0.189609750546774 0.0525357048014451 0.0349166490515621 -0.116432001489912 0.213915520277792 0.208775765233546 -0.0661970636397755 0.0760054813743182 -0.0626616886836648 -0.101835657843679 -0.159155602155687 -0.189369806637398 -0.122375334754122 -0.125853183627733 -0.151970819739776 0.103434164035315 0.0257507886998552 0.151531368430726 -0.0115573655047301 -0.0644288381129968 -0.0732126585559638 staurosporine 0.0301462080971622 -0.0902591438300604 0.0312387077806545 -0.101881841019799 -0.388479052090073 -0.143441594137684 -0.0198687896079032 -0.227614209752328 -0.0502064958811961 -0.197036076540451 -0.21400000509273 -0.2030918100452 -0.227000617595603 -0.201249839293036 -0.305854483499642 -0.0874514504735064 0.0458554801362612 0.00642635790334894 -0.143461796839504 -0.0037718136806035 0.0131133070590446 NU-1025 -0.126444555062168 -0.0919635708252177 0.275256538761858 0.0388389832811816 -0.201971170518012 -0.227491980271251 -0.163574212736057 -0.0235856065980797 -0.272753821139503 -0.165529783884292 0 -0.342706872531963 -0.391142915904191 -0.275360712827849 -0.234730831860179 -0.190976831134455 0 -0.229974563777191 -0.0452019137881304 -0.00701765673117372 0.184534140569793 acetylsalicylic acid -0.0791079796882509 -0.432299023571318 -0.285468195173715 -0.421527137242847 -0.404666091828037 -0.13913353906704 0.0234659725746549 -0.408412325520865 -0.277090391395821 -0.38942919738986 -0.272497779108591 -0.279524471556962 -0.353151385050777 -0.489439640419072 -0.504219514944532 -0.505076203330559 -0.306898160935174 -0.514080208569252 -0.478950710891638 -0.284575345408734 -0.29372340880037 flufenamic acid -0.0619215818220168 -0.508184489732983 0.434533197192474 -0.506264929938404 -0.382968955162201 -0.148889175824707 -0.149391509142387 -0.466205815725406 -0.446023267936951 -0.4452992489732 -0.334486787909997 -0.39389682290826 -0.494611272906524 -0.574783616908919 -0.509534590931786 -0.554785530627156 -0.372754790452049 -0.498398998266128 -0.617367817964639 -0.272905882000622 -0.264660407853435 N-phenylanthranilic acid -0.403311739193382 -0.372333736089854 0 0 -0.435292024366576 -0.396830229247492 0 -0.456552000193672 -0.35389655868878 -0.490703679728182 -0.332613120240907 0 -0.466327458798403 -0.426795366426752 -0.359402642193143 -0.345590067794601 0.314210223396868 -0.301467390089708 -0.321223530481747 0 -0.4314207489833 monorden -0.151886549859102 -0.229714193236703 0.109210556225364 -0.28146215528852 -0.059588150036147 0.0478078809568918 0.0190462567200449 -0.176382326965692 -0.210970851192608 -0.194887796996315 -0.0444621504878053 -0.202943034157304 -0.17908731903675 -0.291143029784081 -0.267490405708584 -0.25981458640958 -0.204324885553676 -0.374311227153982 -0.274775036220583 -0.13141183644267 -0.124982567328387 sirolimus -0.367328806203055 -0.363268514676917 0.0918085794116975 -0.368113678148588 -0.303951613775704 0.04476333526112 -0.361301248910128 -0.3779930286803 -0.192865744161054 -0.311798702613623 -0.3185994878295 -0.388823240186237 -0.348326907560533 -0.312145503339772 -0.302833661189189 -0.338959156701394 -0.432277749336798 -0.323618535685537 -0.307552004829267 -0.315481700662391 -0.462466662879492 arachidonyltrifluoromethane 0.266485508654358 0.520906143828607 0.20331149210777 0.303754004752036 0.530133558148485 0.310391205884264 0.580130581762604 0.506344762047884 0.254538563411963 0.545348826140656 0.264682606504428 0.256284307326961 0.492535791455874 0.297417197893241 0.263735152192954 0.585032185007814 0.32831501208298 0.572126340753558 0.291646640230495 0.242015285662046 0 trichostatin A -0.55585745215604 -0.455630750774984 0.216386339455534 -0.594609643816793 -0.506851368636656 0.042526451251979 -0.566084282920511 -0.602760547204111 -0.400555060394055 -0.620316537270569 -0.470424525080678 -0.575056813530109 -0.413718498939138 -0.533181291766529 -0.529697417632513 -0.52193847411509 -0.640132117617032 -0.612779847923916 -0.483059352862086 -0.693187600214995 -0.208076169874881 diclofenac -0.0479407350700852 -0.167254928476145 0.129375393716538 -0.298339213507598 -0.2624527374195 -0.0199730616144084 -0.211399523462877 -0.373001039378219 -0.360745753439028 -0.214628738492917 -0.260938553767176 -0.200515974146985 -0.184940086742839 -0.21295947888898 -0.203915596987838 -0.26748801019376 -0.176390979138319 -0.209125372654274 -0.50580431275853 -0.0527402686559877 -0.355672016643328 mercaptopurine 0 -0.203202786420833 0.283412673512283 -0.206204401672693 -0.413130598743949 0 0 -0.500253449927088 0 -0.464405640722737 -0.413239086224589 -0.453106186090244 -0.449619196776184 -0.474048756782741 -0.591202928590625 -0.447545795847577 -0.189876605957858 -0.206200001971948 -0.469745777899757 0 0 nifedipine -0.0501477454273686 -0.248421330831771 -0.119372026312531 -0.208929833673828 -0.26654367659254 -0.408480031204097 -0.0821057497717122 -0.417999943788289 -0.192529025804299 -0.335648837306757 -0.16656540590476 -0.153579035515125 -0.235294647660007 -0.293563729886714 -0.452954308356863 -0.15414710101001 -0.241864882307955 -0.192362601952797 -0.308875597767053 -0.25165762785816 0.0662242329285754 nitrendipine -0.0952615558230545 -0.289200533353633 0.146844111093428 -0.248545316408093 -0.283517449324967 -0.0703048825741718 -0.0906544892378332 -0.335284131940777 -0.341633788533417 -0.398155293023815 -0.261042550489335 -0.317709165083919 -0.338056764227732 -0.375791351080699 -0.380534416940555 -0.285075079401242 -0.14762346153875 -0.287261551367936 -0.355578164040505 -0.280783286706201 -0.361915407397033 felodipine -0.419557509025092 -0.384408540404447 0.168464629706018 -0.320481684939097 -0.487870341444002 -0.244128514510102 -0.513948400834272 -0.465622294726655 -0.355875136839639 -0.501125610182359 -0.471084539249453 -0.484943255929379 -0.484192343645472 -0.518810748654495 -0.499717289485784 -0.456706281452869 -0.455679121574559 -0.541758395131874 -0.243767419372284 -0.378047797214997 -0.289707893912837 azathioprine -0.215830152843707 -0.0736562935901509 0.197948388268575 0.0836173951722789 -0.0723752910860425 -0.00931183260387877 -0.196601025002975 -0.251092601224674 0.0737404681591539 -0.24583120780941 -0.0486558050161372 -0.240090410542218 -0.196980215781125 -0.229357200994859 -0.232792678712936 -0.0359017215577498 -0.0701891254801565 -0.265301535200182 -0.0388873739230227 -0.174425863177747 -0.241288129947135 sodium phenylbutyrate -0.224497937371914 0.0829745275086564 0.113430991848936 -0.182295083060513 0.0410573857137019 0.429869003280342 -0.0174200658110123 -0.00556860884784766 -0.117211027429115 -0.021941589385475 -0.0181113521915492 0.0460834341549336 0.0852451846218394 0.169672302247992 0.0628447992493305 -0.0371660639111725 -0.209712085865905 0.0209015964684395 -0.155507710989736 -0.33564611989452 -0.155261318977538 novobiocin 0.105167764178967 -0.106417615544518 0.0790960437813997 -0.162830569860293 -0.0391045753631288 0.154238125575513 -0.105732611600986 -0.126934862903704 0.0458325342714873 -0.0421706032846431 -0.0839349213427107 0.0716402678605368 -0.122333766533945 0.023969775158082 -0.0363380053371294 -0.0739758691647082 0.0969647197193597 -0.0679496175535342 -0.282455488440287 -0.0811103906340413 -0.145033036793834 fasudil 0.063086828577276 0.0806835631250627 0 -0.153171730456024 0.0309123582595362 0.114030534239649 0.333063404022075 0.0103311312329787 -0.023039116693923 0.0451176525790094 -0.00862522942126678 0.281982225181277 0.0160448252507298 -0.0104195759992271 -0.285189495039982 0.0783773359625639 0 0.0747991888423729 -0.32383477788396 0 0.336790582446441 2-deoxy-D-glucose 0 0.412843915226995 -0.516398546556981 0 0.439963443544137 0.637806477964669 0 0 -0.301887705241174 -0.357953339802135 0 0 0.364622121965539 0.405751780511202 -0.508172134169708 0 -0.343797066416441 0 0 0 0 imatinib 0 0.416680855705224 -0.0344900507241428 0.427821544525308 0.180737537234797 -0.0968746758208599 -0.148379045449932 0.236198310933608 0.201267628159184 0.178172063852944 0.0992958264524077 0.179361683176849 0.351303396782364 0.416383932605202 0.259829928719021 0.503098867251707 0.26844853844234 0.460978249868717 0.408285832861966 0.423906800032565 -0.150927706688094 pirinixic acid -0.0393551886722036 -0.0636914628527626 0.350398349505312 0.0770446400956437 -0.234005357982733 0.108760230305678 -0.180800275770689 -0.224851590930872 -0.0342300049586252 -0.108048105056259 -0.0982660477189587 -0.140696371069284 -0.108620690354225 -0.0755350959363968 -0.269981707986721 0.031476424645619 -0.00281193561551999 -0.117381729502044 -0.216912799400403 -0.0774445923783639 -0.154486805010441 rosiglitazone 0.144721841565296 0.000854680598717608 0.0700092935217424 0.0229808606533638 0.00811908972080217 0.0274912672156111 0.0228567473783232 0.0103222215076771 0.0363244551776271 -0.0435330820787292 0.0932171909117716 0.0381825719579634 0.0813850746078215 0.00897023048356537 0.0177065312471975 0.0354154472326751 0.147452668750805 -0.00876808191934325 0.0270868078572001 0.0169704710974081 0.0520465688732533 troglitazone 0.0242565118220291 0.0267340519254211 0.0801425444216415 -0.10628556818695 -0.116568930143089 0.117668203957772 -0.147238188086652 -0.177508756770255 -0.0999829354541736 -0.054258084426573 -0.146721851697641 -0.0563300159374163 -0.188105502393766 -0.154533446915207 -0.145879601709931 -0.0278184928079946 -0.0581279541622363 -0.204634975146703 -0.0362635127414588 -0.196464582517961 -0.0806012865893411 cobalt chloride 0.0758033281948049 0.107622311156873 -0.614320469537918 -0.0316859886729993 0.268684251615056 0.174624448868622 0.00867728724196842 0.0306062055649502 0.153849664545432 0.0154518169584527 -0.119565435976921 0.0181523559915023 0.0185278679721794 0.098965522496372 0.0353473972649132 0.121993556238268 0.0240296653540738 0.143854443141414 0.142333740549398 0.0225833325566964 -0.139365680056437 wortmannin -0.334877850507972 -0.0768807412424619 0.124124178223996 -0.165512245890567 -0.0360177710309996 0.0330914641064819 -0.285740071837229 -0.0869968027493804 -0.148631851346806 -0.119589445808056 -0.265610137321315 -0.255738377467803 -0.140890353216054 -0.0920824472194952 -0.213777126042216 -0.158418120375041 -0.312053284921047 -0.0747721381572841 -0.0923064529123545 -0.313016939361134 -0.38156571318722 tetraethylenepentamine 0.12278639381315 -0.243159221323552 -0.031679799507731 -0.115427100679211 0.00962456452855479 -0.0646190330320739 0.0411418204679239 -0.185108734930559 -0.166189771097859 -0.300034863943976 -0.0451047936727852 -0.195276940401352 -0.110303819580802 -0.184870408609694 -0.028873073565763 -0.0806406670500047 -0.0825461846458281 -0.0148134581885768 -0.203151988000711 -0.02109951806882 0.0319541164637126 clozapine -0.122984353163274 0.0179991954646026 0.0472811250929652 0.0335325471536261 -0.0597035060308337 -0.020322173263842 -0.0203365614491635 -0.0487921591253651 0.0387887209741705 -0.0123872915569977 -0.0455380435700336 -0.0061662026742395 0.0314366145394065 0.0193667505304602 0.0142885168054499 -0.00352684879412264 -0.0121583663705654 0.00759587524480797 0.079508670936289 -0.0396424481527195 -0.0885185422259536 thioridazine -0.572535031386879 -0.444770890173117 0.21593595703846 -0.411880020908688 -0.390167632007372 -0.164881344227632 -0.561015570340443 -0.451934935038145 -0.453348142597939 -0.518232762286108 -0.530495957633083 -0.533428338852542 -0.48539557106092 -0.498249011696783 -0.523341867206669 -0.402596061201765 -0.460984024100376 -0.47184544098108 -0.431603693172428 -0.459602165492181 -0.378264160862105 haloperidol -0.0157785676311986 0.0315332727785987 -0.0362035051888992 -0.00960312966457794 -0.0370173618809487 -0.0652118626579013 -0.0564738540576309 -0.0402475331937215 0.0180866665120226 -0.039314235691747 -0.0763340947258876 -0.0440686180394742 0.0281003531049162 0.0121549047445531 -0.014956977280822 0.020451719746905 -0.0228505725905967 -0.0589158169253095 0.0466403758658483 -0.0527195392535584 0.00153935207318302 chlorpromazine -0.215220983686686 -0.481814510347244 0.31897166649898 -0.430131949936039 -0.474950225714435 -0.109895328742275 -0.311111814665499 -0.501214072981686 -0.360823702294425 -0.559892900857087 -0.370462325089307 -0.460682808920846 -0.517868380270904 -0.478248001049714 -0.53605614702639 -0.497978428950533 -0.411431152129396 -0.522817050456889 -0.502542638594811 -0.376368226491001 -0.353903228957875 trifluoperazine -0.518278262246322 -0.468930223482486 0.103392644998133 -0.510781811115911 -0.397153235319097 -0.124474536954715 -0.596079732476192 -0.455481091111016 -0.504499528484097 -0.53577547645061 -0.54908172735053 -0.57335094101455 -0.509904201579198 -0.499893656772003 -0.534666938563409 -0.487514234558786 -0.43575041024913 -0.513997213898638 -0.452968179854229 -0.50768569109325 -0.45634615441895 iloprost 0.380207734387866 0.537265584714608 -0.154559411237411 0.26950352717926 0.549093009055333 0 0.346716306751282 0.543456966641842 0.451151717439108 0.369664398775724 0.0682850715875101 0.387865693410717 0.535350036079903 0.58848572048839 0.61778937287872 0.552723766526168 0.571689249419862 0.615938373202304 0.535626272720744 0.531888462172306 0.421599775806122 copper sulfate 0.00523695050650547 0.0262053237495322 0.229578823285434 0.159252902701711 0.0620120655574876 -0.104029538229042 0.140898217421713 0.043185875404591 0.297318248969265 -0.111080747493147 -0.0821148056270721 0.0322859901594133 0.0305183659578998 0.112462888802988 0.0214691163119984 0.0420823527312118 0.122379844676151 -0.0780357831592601 0.146114786266966 0 0.307206352958985 oxamic acid -0.614869436311393 -0.385782959837689 0 0 -0.612182946282755 -0.595783053993864 -0.727550435764326 -0.662791494038999 -0.364944644010052 -0.559595281812985 -0.530172604158706 -0.536731037501606 -0.516136979928121 -0.445446662793379 -0.612598460060258 -0.391275354371857 0 0 0 -0.445029008119927 -0.454174594755907 W-13 -0.469391568582642 0.405698438349135 0.214786203535678 0.463237679043589 0 -0.226582744821815 -0.36541218372024 0.203667477200134 0.218145800263324 0.398944351355574 0.176257258389429 0 0.452524078584992 0.251291308727495 0.474799980215426 0.233542716293075 0 0.205477545455279 0.507452956594668 0 0 arachidonic acid 0.0469383791251498 -0.293407492645124 0.334944261368045 -0.161707040370919 -0.0468107026753536 0.30014813568683 0.0653785274369187 -0.163772459666596 -0.107784563321902 5.96380068766574e-05 0 -0.040266860213722 -0.0295638533224686 -0.18578631321328 -0.187319194275167 -0.0422877974447242 -0.0115775372819992 -0.304285743442352 -0.161737090303823 -0.236203153558754 -0.143359382340319 oligomycin 0 -0.35565457255795 0 0 0 0 -0.276006260479494 0.412999421899191 -0.40121834690297 0 0 -0.357960896509503 0.415036179239733 0 0 0.342602971907687 0 0 0.400622020179512 -0.345539636256079 -0.497507357538568 prochlorperazine -0.456811019563491 -0.487084713061728 0.0480747273945959 -0.493474012890582 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0.826802903348582 0.744259524840613 0.633073169566675 0.766236791756341 0.571215583837768 0.746159276301457 0.741963144017896 0.779511707530866 0.743143135238501 0.741452966267534 0.590516831969251 0.691254115816318 0.699577673640848 0.637998188431848 0.507695935886369 decitabine 0 0.711680960468217 -0.590894655845852 0.61547572138519 0.719012643354891 0 0.676747193286527 0.69716001941616 0.644778871112259 0.654734856137242 0.515951953551335 0.611311194533943 0.782473712887286 0.750995748627545 0.634777550153146 0.752214581436228 0.53968280741531 0.748904826597811 0.698965014236124 0.580971385914773 0.552696386313065 alvespimycin -0.231430840284305 -0.440235329833897 0.0747891067452424 -0.437491557564828 -0.134504113476457 -0.0277076733531218 0.136095034808596 -0.280285406585711 -0.236458148693451 -0.487517205247082 -0.208290553093455 -0.421814590222669 -0.338869453750601 -0.375365208161633 -0.43508855958902 -0.538112939192661 -0.401794254947673 -0.559141570386249 -0.539355229101644 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0.64643298566779 0 0 0.637932878029695 0 0 yohimbine 0.135890138478146 -0.141650400513109 -0.0678872405597174 -0.0878060055055178 -0.133171120808066 0.0739672885372702 0 -0.17167963237045 -0.0191128909595306 -0.237464434879215 -0.131829621847447 -0.137234047685992 -0.086562319000115 -0.190379613654679 -0.166827651392614 0.0501427792691741 -0.164755753044348 -0.073222978959491 -0.216402704425263 -0.294885572238137 -0.156412066955295 DL-PPMP 0 0.957960174226351 0 0.943195110357498 0.884615108425872 0 0.823777937510662 0.887320018220917 0.782872848284882 0.836868858030648 0.686329327219072 0.960649090317337 0.975342359778707 0.970508767037062 0.912008455283403 1 0.839196702669164 1 0.952463473788775 0.860098556990174 0.70687884836711 cytochalasin B 0 -0.541312468072943 0.520354197932184 0.593523827201126 0.551568357217506 0 -0.49776650913214 0 -0.497633511446465 -0.643038175143447 -0.552986426094279 -0.605732154312226 -0.626421333922309 -0.713781169636787 -0.68163329110597 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0.0619307554996243 0.315301546972143 -0.168786108815594 0.00343567479316677 0.295187180938658 0 0.00473335641037981 0.308436675972325 -0.0857044739068368 0.188861342011949 -0.0878584910444092 0.186433021450602 0.261535412824853 0.284505908111508 0.313540874505838 0.140211474914454 0.0111910980229875 0.260955777012317 0.0882527618453961 0.285981315658074 0.305899223810296 chlorprothixene -0.426130175609684 -0.244548879539696 0.212982506859536 -0.0797626441741736 -0.120442851700381 0.0188549050296154 -0.420213266302366 -0.243546677328924 -0.319819517341987 -0.308710228411056 -0.426028506331877 -0.290248932780584 -0.306119284647204 -0.316387067161258 -0.35273791477065 -0.265011919455173 -0.232997101896548 -0.317265151769153 -0.266938451306547 -0.416394942196967 -0.114987209460023 cefalexin -0.196910269700277 -0.580389460548805 0.0826508053780859 -0.439224583218749 -0.617716578357271 -0.210520779935569 -0.10137474416932 -0.605040899163616 -0.482343850259166 -0.561034105551799 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-0.425210580918917 -0.275024966458312 0.217671828981924 -0.207554296645956 0.167093571404486 -0.180588913827942 0.206454810121756 -0.117594605059884 0.0236891828210878 0.279685525571923 -0.108620625498246 0.0259470383286961 -0.116414783523566 -0.349483450569554 -0.173264334026166 -0.103271359101073 -0.180205529908806 -0.290954059299746 0.297597248916979 -0.125431795871713 -0.0294170741663375 carcinine 0.00209649334169712 -0.272494692490974 -0.141450071130453 -0.400387799851287 -0.267011687599033 -0.0110287714197381 0.0645102012562851 -0.262329377150816 -0.0290980776881054 -0.178827640496045 -0.191517117853663 -0.23694075299673 -0.277377229708672 -0.204734960036629 -0.0578342697215658 -0.305086303963632 -0.367349494709698 -0.211757649174751 -0.224892417663 -0.362016172261254 -0.150980507159671 corticosterone -0.150675332582952 0.0765867244484015 0.0817313485335227 -0.0883350567549811 -0.138120838748909 -0.116309924041458 0.083766366870812 -0.0274571769268611 -0.0796357171384869 -0.0702301807640288 -0.0163689458182964 -0.0214003918652269 -0.0492252505902181 0.0973577788612915 -0.0836004184850998 0.119122859591024 0.106726171038742 -0.0372117259927127 -0.116550632449825 -0.152773193718951 0.0182457856141071 fusaric acid -0.118672966855213 -0.612229503074706 0.141341223621674 -0.520433288586969 -0.575431778916776 0 -0.214394376891464 -0.592489281591467 -0.368291017750467 -0.616941071610906 -0.220747465817348 -0.422305332117388 -0.546543095195293 -0.650753221090837 -0.480529860407259 -0.592769685062316 -0.509378283869508 -0.631599007606553 -0.619329049202237 -0.404117213481937 -0.3158519361927 lactobionic acid 0.197655855211555 0.0186587886818198 -0.344339442049791 -0.0343990776426476 -0.0243735572510638 -0.184807838015488 0.186066439921899 -0.0187021448921336 -0.088441534327034 0.170202581603515 0.0355144152808502 0.124594150840057 0.0552258164463386 -0.0461544483839456 0.00628740190190315 -0.00540158005400114 -0.0999581558431073 -0.0649657464733298 -0.146651398972822 0.0020537304915445 -0.141140744656324 cefixime -0.018602707348774 -0.0348501938168017 0.148518790245751 -0.0144051962609859 -0.191506614391083 -0.370992541227687 0.343810633756703 -0.239401174318854 0.00491738678633277 -0.0317819332327218 -0.0188506444039071 -0.00687181956437694 -0.0895085541815427 -0.0982910935462931 -0.0950484270103374 -0.0494442119422086 0.151918317658233 -0.0641862712542977 -0.0796364586296346 -0.00793875783149472 -0.3049787061447 calcium pantothenate -0.134229109720819 -0.538397030937648 0.0893120290837818 -0.251658993152587 -0.498002167493827 -0.21726504600285 -0.128371004793653 -0.560996537349631 -0.40432393407707 -0.303426790640938 -0.0772676551302517 -0.396683560481021 -0.456246050140963 -0.57429812872971 -0.541466097845635 -0.566744348035546 -0.386107057615582 -0.447187133353178 -0.275249567919339 -0.38075895734003 -0.274455135274673 levothyroxine sodium 0 0.110008372714375 -0.0418197110932993 -0.111836328788699 -0.0063977694812813 0.0940842262352855 0.275621188204434 -0.032668217131224 0.218770314492302 0.0646902917010003 0.195381168054033 0.138587409491177 0.0684217947318256 0.0350616239004425 0.0771273322035519 0.0542281813127731 0.0915605737135123 -0.0351405390764168 -0.148673439225249 0.157653235675622 -0.0968750720901184 carbarsone 0.00399489379480102 -0.126205455187632 0 -0.162410473515516 -0.145361240160999 -0.16873615896928 0.0553771004399789 -0.227469220564449 -0.123851444831519 -0.210897434891597 -0.0969201815155805 -0.180449352031024 -0.0827326710582173 -0.23147019436869 -0.239664063660186 -0.08382476891652 -0.163609608940082 -0.117155298692251 -0.148657853140293 -0.18185174103139 -0.337087993526719 carisoprodol 0.186151316931624 -0.0267145666356133 0.104599041043338 -0.205194197902069 -0.0417957132425033 0.179799071489473 0.353323180369518 -0.0710897479115523 5.95412093643e-05 0.00553074386345784 0.0766077455987192 0.0665711329315611 -0.150364595447989 -0.0229578858165775 -0.00992266563632263 -0.0214604843669641 0.038879212334544 -0.0306578436992504 -0.188638428902648 -0.012418150631183 -0.137135490254667 cyanocobalamin -0.102352902988868 -0.241702089005 0.102931672090478 -0.149870129664517 -0.258339147375628 0.0653161750605113 -0.122654719339469 -0.283426612746904 -0.231800516983164 -0.239746976840431 -0.202857303532114 -0.178597856274192 -0.292425599347611 -0.289697301874545 -0.297611924603954 -0.288995486428888 -0.0899022519374108 -0.238118160483869 -0.326585502415482 0.18914419204048 -0.290311219443732 SR-95531 0.265977728804752 0.047201561377311 0.230649767708226 -0.0833088494804802 0.0223192634942921 0.278518350073862 0.26817150308765 0.00396077946383704 -0.0274271494054609 -0.138441468071609 -0.0212524199594563 0.074275406872848 0.172080334255028 -0.0874055198743639 -0.0917577897425685 0.0440157401683541 0.0720749443923877 -0.1836266270753 0.0712455431493469 -0.167806047583596 -0.0284529420384535 lumicolchicine 0.197053404857199 0.0508833915705975 0.00287570050058152 -0.0925831603051063 0.0237870653499596 0 0.355594747628761 0.037127217467311 0.204660578716891 0.165332892333008 0.186100564660832 0.146848812283636 0.102729616658205 0.106371598485917 0.118962073527576 0.0802724153299821 0.0201505978633136 -0.0916050588330223 -0.0299974628731899 -0.0545005489680244 -0.0299411679918554 metrizamide 0.288401844123345 0.298766569856677 0.114409403725567 0.090542307354021 0.263994809586121 0.311163508694452 0.513332378036544 0.21040189262228 0.195608915573393 0.225062566797089 0.104216145921468 0.399134240224288 0.339188353118813 0.326895485828206 0.184392143334949 0.301767775086317 0.0874201122279156 0.274355037200284 0.137233349813905 0.276730883107295 0.426860675080199 cefotetan 0.277085436020488 0.151635715212634 -0.209294394526448 0.146080563825659 0.159331126311602 0 0.151159647072152 0.000366815260117781 -0.165313565313104 -0.150465129224515 -0.251377854718503 0.0306084398597246 -0.0106156682438517 -0.137874932472752 -0.00180902964007982 -0.101662140354838 -0.0225391766431517 0.130755733935254 -0.232705462480465 0.0252324791917917 0.0353096024519217 dl-alpha tocopherol 0.0599071625526731 0.0303971210835743 -0.141267419554047 -0.00411795328873742 0.0870178462161171 0.197345019584996 0 -0.0485823869520348 0.0860381864297312 0.0763173999792822 -0.00103262373503326 0.0908918062228604 0.078528257915904 -0.00632739357450432 -0.00724913640470332 0.0164948185016723 0.0877395580379902 -0.00928034013330237 0.0332350843839727 -0.0335239404467672 0.178157675161248 apigenin 0 -0.678247218052626 0.531319765586674 -0.49064333324801 -0.76366615212367 -0.117111213839067 0 -0.799495923690177 -0.639633743618025 -0.742232831615454 -0.527996140545759 -0.630294447759861 -0.752553551581091 -0.769110373443337 -0.768582012341645 -0.688093485893994 -0.156444155041759 -0.702324709169606 -0.829336700403632 -0.26343768158192 -0.704990390804453 7-aminocephalosporanic acid 0.30995170993924 -0.139877038709158 -0.0934603714619791 -0.0610698940885297 -0.0140625170422863 -0.0256406202791327 0.0695249713527211 -0.0554064034456647 -0.232601378055904 -0.0650274011004553 -0.0798621568357205 -0.0328173086393321 -0.0942472991667299 -0.118183023642344 -0.128010921874452 -0.0928367881656254 0.200337411472589 -0.178108120786399 -0.276976025378887 -0.154364373635397 0.0504146290501276 cefadroxil -0.138089434534276 0.0597152558261626 -0.130259862437535 0.0705737905351355 -0.0733233095255855 -0.249546377943846 0.0249393781068089 -0.0830712091576988 0.0570732541810255 0.0656664894999616 -0.060877257209482 -0.0043022748758158 -0.0579858924362016 0.0651689857915977 0.0587590322745877 0.0705820356500383 0.229687964398358 0.186285851219388 0.0450616862790892 0.130193868515506 -0.228654005006275 ginkgolide A -0.152748639203914 -0.707535992319366 0.259147879030686 -0.544693337968918 -0.690314144306611 -0.210831854248963 -0.278536319552903 -0.72298366516586 -0.569382892801208 -0.681385540295908 -0.466304679219531 -0.639346746929863 -0.750035723465289 -0.728946545012739 -0.702990094619487 -0.689183256487596 -0.470738956335228 -0.511663529127449 -0.588878733150959 -0.262421017897576 -0.644539891930931 lysergol -0.276910200303221 -0.551388934595558 -0.0297536086525394 -0.3379434441469 -0.442853708023104 -0.357944951769389 -0.125271657794921 -0.597851478712297 -0.45115346529636 -0.518284966354038 -0.300191107117137 -0.390325275118453 -0.468134937913992 -0.505560321959004 -0.387762217530167 -0.440946937315345 -0.122935126678798 -0.339439328671181 -0.402277755511429 -0.190955174514711 -0.38802071024115 N-acetylmuramic acid -0.00575274791468575 0.288565858004528 0.099558878697961 0.0221273793567656 0.243483714343433 -0.123059675839046 0.119530493290206 0.138250186023166 0.225204553517079 0.302460661225576 0.126391101473421 0.331621970187356 0.165155031174937 0.351914362741319 0.307681252309535 0.322952359208755 0.211760551833928 0.0629042885202779 0.113360800281379 0.263240573826585 0.182287228316783 piperine 0.113391668213279 0.118177764673866 -0.000403676280476106 0.0441252667804527 0.066039034378793 0.110573249354283 -0.0698535143373453 0.0378563619618023 0.071666005246397 0.0896652307263402 0.116538527570874 -0.0339007053973386 0.107543624185137 0.0899863346318084 -0.0225336733814469 0.118358230968929 0.137847479007323 0.127058786662375 0.00871306943793407 0.0423337263428051 -0.288781252828433 pepstatin 0.0946087608156508 0.0354939568527762 0.31455370170677 0.153122893225618 0.0698364382022799 -0.125756174780472 0.12834280991995 0.189689687290937 0.223216761344673 0.364659767044988 -0.0452534810246261 0.143776126259439 0.230869429391382 0.165841501414519 0.330604808920392 0.0810471689698948 -0.0438385633477079 0.207999208326094 0.219912977059606 -0.0981198394085304 -0.0920089334979139 N-acetyl-L-aspartic acid 0.160808050196936 0.0383125019357033 0.0168119800096812 -0.182743050080638 -0.0527899527558766 -0.0291605789680362 0 -0.0663375396777332 -0.121377786036657 -0.0301530075785346 0.195915261218631 -0.0114885425691096 -0.0301834550821959 0.0587289057484428 -0.139299566825092 -0.119502996145735 -0.141702612116241 -0.147687624144714 -0.0349446660202524 0.0820954520645154 -0.162062226436876 Chicago Sky Blue 6B -0.018835320429963 0.137996341203598 -0.235844460197631 0.4650876289525 0.322745079591697 -0.122704921973781 0.0339878788010275 0.322503368001569 0.361193589238238 0.179377560556248 0.231718934307987 0.164786119963736 0.345328728607416 0.124154144312873 0.224145963860926 0.328115569582903 0.375566683123909 0.313540113927995 0.40269647369299 0.379527283956794 0.244588542489564 cyclobenzaprine 0.0302213917991095 0.165223377684966 0 0.101988343907485 0.0519878694599449 -0.144239545059881 0.0034728516460695 -0.191473130229521 0.17477523788651 0.0953058835919525 0.0292354017875817 0.0449163013700032 0.17299244299924 0.249347785958609 0.00105998835873355 0.166019913971625 0.0467434797241913 0.012826653095332 0.317289856767326 -0.144909622319617 0.329664909209861 mebhydrolin -0.177091534207892 0.280259581040484 -0.395704223791821 0.49856948981568 0.233712170921458 -0.124291014426837 -0.121408012875049 0.299689921095096 0.351264838566463 0.421279054592937 0.104331139737738 0.259403010244242 0.0396926922646705 0.43524910214287 0.407407498134805 0.431451853002743 0.140755469742229 0.364956182944643 0.32094294325974 -0.0852312568496477 0.379745134416229 myricetin 0 0.376416026870814 0.23056497081853 0.411129394568503 0.222451715433874 -0.131325601654139 -0.133448215143478 0.21340512471143 0.204473180398383 0.380012472984941 0.0220591887790151 0.32594866028095 0.366180953575335 0.199436383421177 0.229206964300194 0.403554998529984 0.213169591691653 0.245147111801089 0.404819739249641 0.304410638519167 0.497458601572246 brompheniramine -0.103882323127533 0.0148873481786064 0.0585877054437202 0.109547607842814 0.115622026130237 0 -0.0998304802730166 0.106278892170801 -0.0503889264426978 -0.0675767312916159 -0.12408582547982 0.0138850251487282 0.0349273184151875 -0.0191289283920803 -0.0329994420050444 0.0303386047679089 -0.0169163331055008 -0.0137669511953447 0.133740917783679 -0.23554530420596 0.164133776353493 SR-95639A 0.0148637171978274 0.0695970416591207 -0.0610657034144983 0.143287589474868 -0.0830703419022949 -0.0956242856707124 0.116194741777848 0.13251379580395 0.269161134443856 0.172750121152811 0.086368076688474 0.160428861930994 0.104829470776259 0.1077492138524 -0.0831014394915518 0.0666608397083098 0.295632237113759 0.104057499197729 0.107961996174058 0.11266113787203 0.230489720275659 bacampicillin -0.0605161856084688 0.158815524989878 0.195460986840459 0.137966457388238 0.19659333173048 -0.180414465003505 -0.103859955871072 0.10179762726202 0.230836047140475 0.1433331010102 0.121491716491538 0.146546483585743 0.0845802729478845 0.0578749072028284 0.316924390995606 0.0835895883340735 -0.0846040202493986 0.0823824436485173 0.191734780620797 0.0743756240048277 0.181592782514864 buflomedil -0.0427879704983822 -0.466149062556149 0.108840473631174 -0.246707698941233 -0.441781052629374 -0.0245600748660375 0.102453768193233 -0.574461822690009 -0.397727534658815 -0.424619316348284 -0.201372433953001 -0.515204325113257 -0.500363144960787 -0.470951168971737 -0.462240248892459 -0.451822019150539 -0.14022327645603 -0.400884499000769 -0.246469229989631 -0.266093121182082 -0.174887519730838 digitoxigenin -0.452172360695112 -0.265551672196346 0.237432383892782 -0.178258473032898 -0.25723971831961 -0.516607514748075 -0.264961826459777 -0.0689063555588003 -0.128463653967083 0.124853339918775 -0.210642489592003 -0.319557151093555 -0.410041841792558 -0.138023060649072 -0.0495348559204199 -0.109988230117971 0.0407431308885195 -0.0872125739660374 0.0149175913246579 0.144726375074466 -0.124044303578414 carteolol 0.103151080588145 0.20817230699602 -0.0133494052513543 0.238299412758475 0.223189430026513 -0.159896982512734 0.13106956337801 0.412918498909613 0.343592204791027 0.327698530829208 0.369034232482228 0.204971019011303 0.310903824219689 0.331441816221845 0.42054090118973 0.242313152312265 0.319161797238261 0.38557624940114 0.399420752361877 0.118955216186233 0.310205573410584 meclocycline 0.165093567490244 0.14209683782923 -0.125139168276834 0.364897438285426 0.137257075589376 -0.235512289401042 0.211621854880085 0.1348602408735 0.294744647214336 0.194969031918424 0.170229826504418 0.0728635713504984 0.161799445526723 0.166823273755989 0.167657406184775 0.14091280657174 0.345105372297074 -0.0425602774601583 0.169899608861928 0.25356821782125 0.208638376210088 naringenin 0.172730117928842 0.645730064500762 -0.382826014932719 0.529417597742224 0.64502829650508 0.2117090393523 0.25706054914935 0.542911002465625 0.674506175611969 0.509023183254943 0.339236138312057 0.581742911209736 0.587366958593394 0.693311033765598 0.672408535544597 0.713665945903244 0.46909205754989 0.539890692736863 0.558207367681285 0.260177785649026 0.510289866079675 primaquine -0.200953789722586 -0.307787687716486 0.389322741869788 -0.027630557610946 -0.446455851897795 -0.564034269101069 -0.313177737230845 -0.450610962507073 -0.25469964032216 -0.302737833659993 -0.211336522242511 -0.328551427681202 -0.341614338243162 -0.466655814693116 -0.433648008118566 -0.207015850500173 0.200466562178936 -0.163832816145818 -0.0175321409767448 -0.204054032830538 -0.109821320946225 amantadine -0.229282383142492 0.602652136813412 -0.0294970048065318 0.603005886400571 0.289586517659171 -0.0885189914927077 -0.217421681715538 0.285787509692991 0.572894602031723 0.586160024593936 0.201456991830979 0.186023021745771 0.332898996389368 0.609352248405384 0.457329654648825 0.583733833300995 0.50034789596212 0.467733910172377 0.670500364720124 0.475320587057321 -0.106076465895902 betulinic acid 0.039525261534046 0.478945245811059 0.123474332115029 0.534978168571102 0.376545549533368 0 -0.106222801238526 0.393962253876725 0.229159795114891 0.401647135861959 0.369971144742859 0.442297303162232 0.458111000396109 0.42626888737333 0.418508951950511 0.446416146944232 0.507793549223862 0.454425326697664 0.478069784648788 0.333530701579327 0.182580901941369 chlorogenic acid 0.00184174163628159 0.339033630348571 -0.0851942355816397 0.306120461534027 0.292056542210095 0.172604679638205 0.218145829060922 0.320068726168224 0.353694714316797 0.357842255084425 0.294744990510392 0.385035638821256 0.401663598050389 0.408737088570935 0.422495288516083 0.331945739655997 0.203682393047967 0.336896187367254 0.420171355608794 0.127752719116663 0.324984085557203 naltrexone 0.226190659742406 -0.0287824585351535 0.0784731694794715 0.0919350924721252 0.222739774978762 0.0655927365851599 0.246646281834288 0.204024764587485 0.0849678904340804 -0.155861417244262 0.251315450163221 0.143100421723811 0.0303431502038784 0.0109209616975709 -0.104117182965097 0.199851895168257 -0.066669397713655 0.0341701907328358 -0.177581059480814 -0.147139095258881 0.0911752265181608 mefloquine -0.512666795751281 -0.555547373043633 0.0193011107221318 -0.567565560176639 -0.396271193280262 0.11514416144408 -0.532240293862876 -0.489558721525646 -0.513557124286702 -0.53297060990231 -0.565911611974739 -0.602935569321983 -0.549517924841368 -0.712515581071753 -0.718302561652066 -0.531399680756696 -0.565144360425275 -0.673859241362733 -0.553727103129833 -0.355481793089315 -0.626556418227281 astemizole -0.628111149374085 -0.513620153962655 0.3104260232477 -0.46296041905368 -0.50413648671478 -0.385165827549851 -0.657740722287568 -0.603004043129809 -0.611257716804822 -0.641161284750548 -0.609104207490832 -0.65543538875521 -0.676093058269062 -0.627286701478028 -0.685257738837487 -0.554966712869908 -0.498791736013284 -0.630100658869986 -0.426201956498819 -0.548828862684941 -0.405269923669338 ivermectin -0.250709397984261 -0.351503654482254 -0.122914802165016 -0.205509419206812 -0.136458912552272 0.0217254173664103 -0.163801369857974 -0.492645439348853 -0.433098670091633 -0.595353368457073 -0.429576985069508 -0.468342306171748 -0.387007722228482 -0.513740428321364 -0.5894662751787 -0.343415836375031 -0.283694604231887 -0.379019258189506 -0.420372470368178 -0.300747084062649 -0.223587909469598 diazoxide 0.409597785263418 0.0937704051662616 0.0650858295214154 0.224995447380025 -0.0140071176157162 0.334277674453987 0.196767431101369 0.19728378184123 -0.0307994273222567 0.0816515822962765 -0.00946053526900071 0.160955317797141 0.138729705078946 0.0699294875309873 -0.0280782021034974 0.0712247786973253 0.199865587839824 -0.055048636189056 -0.165231568314483 0.260239121531844 0.139918994899896 disulfiram -0.220859332362406 -0.295197717596697 0.0803912282728757 -0.187649103094131 -0.00312022908639834 -0.194374418033054 0.0970339972127049 -0.136629585688932 -0.140820361033806 0.101713101852325 -0.0857322796816388 -0.0356416447499032 -0.090351628675575 -0.311134151667336 -0.258351733089687 -0.103817910391356 0.0408409454282405 -0.374294678059298 -0.230050456386458 0.00819744450557405 0.117963144276419 atropine oxide 0.285070756183931 -0.0679927634100459 -0.180962193354052 -0.165059850260186 -0.0712978176777263 -0.13565858926156 -0.101817165952707 -0.0592097679924866 -0.0589368856369257 -0.240817075305236 0.00219779039852374 -0.0289239292829496 -0.139608612883524 -0.18464300223544 -0.0799518610598282 -0.0412350419809457 -0.0832026442334449 -0.23440524726941 -0.255905994574863 -0.185788898745714 0.00916424645888545 chlorphenamine -0.187426566647222 -0.165568908656153 -0.247880250650454 0.0276969872645224 -0.0806845142777756 -0.377657734190317 -0.0856825697337407 -0.322354953048801 -0.0078945857127283 -0.268147846352366 0.214765953200815 -0.0432757502486199 -0.277878281755274 -0.286378670972217 -0.193333759920677 -0.172586702739479 0.255233487307164 -0.348501494905667 -0.330513449530997 -0.11153267354254 -0.12286805510423 isoconazole -0.461470977481783 -0.371680412291585 -0.00254256530578019 -0.24669933044625 -0.314766447018046 -0.107536059433028 -0.39635236845225 -0.434690249859912 -0.394496561161178 -0.424122571985425 -0.418451124599949 -0.402754952423709 -0.427514894340975 -0.272008289263519 -0.479016098170484 -0.30792143883274 -0.122228071014549 -0.426798210426408 -0.24445554227512 -0.293698410733369 -0.534175524258414 clindamycin 0.215041245622187 -0.175286072425723 0.0587545425341012 -0.21311714069682 -0.118297105438415 -0.0115809340090342 0.312756113438042 0.0223932811964193 -0.0951849896384821 -0.217634402897453 -0.0426838123628244 -0.151877301778303 -0.0294808998635643 -0.158990388859129 -0.23418375919716 -0.139852993061296 -0.0720265591292838 -0.171496224694367 -0.234108409634891 -0.0503118059716322 -0.0968644084378972 nicergoline -0.399734139853499 -0.580435457163689 0.0774961030092617 -0.44322490443062 -0.462208131685944 -0.374627870807468 -0.453031527886876 -0.557372549103458 -0.476169236139896 -0.434563734023247 -0.40691616209218 -0.383640156244141 -0.406423676455075 -0.528786564924464 -0.564036476095953 -0.376322711266696 -0.49514123863402 -0.37078953763391 -0.472751496473599 -0.33381832126144 -0.413426021090611 gallamine triethiodide 0.118291551915227 -0.378413153621027 0.141681349803398 -0.33337366659117 -0.364830410114593 -0.0437081823665313 -0.173513767963328 -0.405236582119063 -0.406703802274257 -0.365896723478292 -0.348454133206551 -0.441806186671019 -0.339220876532252 -0.282626875284776 -0.407020252715203 -0.368653598312929 -0.301728090907516 -0.384295604817059 -0.561804731654522 -0.271390648223281 -0.326060298831779 aminophenazone -0.242132995046209 -0.272661306739709 0.376597661175393 -0.232337440189489 -0.351663128402791 -0.11660949462898 0.0186444664833702 -0.450955144559001 -0.454451181227665 -0.342685997602224 -0.306388186559101 -0.195188237967463 -0.464448714883422 -0.283603782114821 -0.465109740178532 -0.247272413667941 0.116782913983598 -0.279325207751737 -0.334456364586606 -0.120801371155888 -0.360735874507244 acetylsalicylsalicylic acid 0.129073204259157 -0.337872349468994 0.348055075559514 -0.490404260780245 -0.343039733547231 -0.192052951262584 0.152570662158474 -0.344716712980102 -0.163995210399683 -0.25946823623451 -0.10128172483043 -0.208574118352924 -0.174641005039539 -0.362792459501942 -0.462035980245964 -0.327763732470096 0.012755512061672 -0.190995156991434 -0.363129076683326 0 -0.122193815448718 nomifensine -0.0608439209376903 -0.418811414617691 -0.135974833097834 -0.383770976184413 -0.422168370594102 -0.194673344128104 -0.284912250683642 -0.416706660710619 -0.345607177214921 -0.241196602147091 -0.345509265734684 -0.34282392737202 -0.369686666509324 -0.530112174005255 -0.352755928526687 -0.369780184084966 -0.177844264591692 -0.441710714425247 -0.286566456616267 -0.321374856525653 -0.261422618363474 nalbuphine 0.10647755881547 -0.479667854383116 0.127043712177039 -0.46172490899597 -0.156345910666979 0.147627854582213 0.0581918274833935 -0.187391393340933 -0.263928280276236 -0.285209050304478 -0.0476160477971051 -0.158401333228901 -0.341817723423553 -0.295903007686487 -0.338283181437077 -0.389273676108978 -0.253513410377311 -0.424283498895574 -0.454159276807626 -0.182042712446556 -0.166902301619721 spironolactone -0.0461394875106872 -0.218316480238141 0.161776473996287 -0.316311841851023 -0.264612755290924 -0.153284901104865 -0.189215029794928 -0.360000277478508 -0.289304428844903 -0.325045944521493 -0.184896675141291 -0.296539998649064 -0.34196382199127 -0.235546383182436 -0.337848386933121 -0.314237627507887 -0.114432182777841 -0.299494599225002 -0.432031093529754 -0.304355260096741 -0.22956741331485 terfenadine -0.676440174344588 -0.597916028174964 0.285323884185044 -0.54595053415909 -0.522946788352451 -0.296907796499762 -0.497851482434601 -0.594984905039324 -0.61404931197146 -0.634123628653543 -0.59225203072365 -0.63957131480066 -0.73934689644222 -0.696618900333593 -0.66731812850135 -0.640719290220011 -0.550150043614146 -0.678687311417836 -0.608999012873919 -0.552874764436557 -0.504704143751943 neomycin -0.250339202947064 -0.40090458641658 0.135081204254637 -0.435534556842679 -0.46275968405146 -0.214241514842942 0.0291674146725131 -0.454679747647842 -0.192991174994641 -0.331817591558315 -0.123861842982286 -0.27425851378845 -0.352934842522666 -0.406950290397302 -0.369967692204758 -0.380571185116545 -0.161229883413292 -0.397595335939216 -0.30487048607916 -0.294395151387107 -0.253084765620386 mianserin -0.31119576069577 -0.318652562425917 0.305717476907835 -0.392418689072647 -0.314419160382953 -0.283881143671711 -0.299807722200073 -0.337019867456306 -0.0764723887640943 -0.437874042768257 -0.283933297708344 -0.311766040428612 -0.445545723269613 -0.356171714299549 -0.4956311640716 -0.329572194738739 -0.376351476373684 -0.458235813496539 -0.361184341068606 -0.424899097504055 -0.379503427541717 dizocilpine -0.250479333827424 -0.0497843608829361 -0.105042876753682 -0.0496022125092809 -0.0409585861086352 0.0170081110597264 -0.0455560067284652 -0.0498697488210904 -0.0535795877090816 -0.0569082877702608 -0.128335705683932 -0.0467478307541761 -0.114365116457385 -0.0879143813704537 -0.0824848818183117 -0.0518503213917562 0.0491141673094093 -0.0551886330739797 0.0139714010728966 -0.125083690037888 -0.237225277104806 picotamide -0.316232133013153 -0.277454345576772 0.0741563490061456 -0.202559369547563 -0.426869756309152 -0.227004181804695 0 -0.361903557143563 -0.358388988506254 -0.287004523381093 -0.219583143240212 -0.201796264123702 -0.326270055757998 -0.380683725826518 -0.392951840170599 -0.250643287936629 -0.0986125267955228 -0.333680751281697 -0.299163361676608 -0.0839333529337905 -0.243441057209481 pirenzepine -0.228376278545959 -0.182411427533847 0.297880606095442 -0.122625747025451 -0.292552713357446 -0.165068831092231 0.0177946932955515 -0.378404472803925 -0.154262778153507 -0.372964896064222 -0.269959030380999 -0.176290863349142 -0.284539680348411 -0.206594471181432 -0.286285043902057 -0.253932882355164 -0.194729880319628 -0.273641400924923 -0.373239455239768 -0.120052793156908 -0.263848802069396 cefotaxime 0.210242702623544 -0.00693947447242672 0.0841512632231864 -0.0263734692863379 -0.00865045221877816 0.186674568339712 0.0902777340114733 0.0125156744612931 -0.0719874036571639 0.0228676852541828 0.0338704591302322 0.132896756143693 0.0040828335995582 -0.0354746464583434 -0.0277021125611736 -0.014065963116654 -0.168064391071889 -0.0467695628132617 -0.0763875277374619 0.0262792652860874 0.205549456247145 thioproperazine -0.129186512970408 -0.266630444245242 -0.0222739700556827 -0.26225233433329 -0.408068489692703 -0.210454435371097 -0.302980642302188 -0.258966679006393 -0.197836503784699 -0.213143291182103 -0.247529061815108 -0.0951902227567424 -0.240205070599808 -0.277185335750608 -0.323950411368013 -0.177927779376938 -0.0927520809782081 -0.200580205778329 -0.216006254545686 -0.371568769081319 -0.201569784595686 dihydrostreptomycin -0.14062356200929 0.076239287722925 0.0906990528279636 0.0111704423974343 0.0406994926599303 0.0321904366403869 -0.0806771428311448 -0.0350044812168426 0.193042809826553 0.0653568508718761 0.088903125285785 -0.0328158455150587 -0.101643672521189 -0.0163019893475089 0.0550473859772513 0.0808634349364649 -0.0445143278110867 0.00106266838786244 -0.048358856906941 0.0391290387118441 0.117760120684409 pindolol 0.214170737916845 0.362352450156646 0.28482742962072 0.170789571783494 0.260839459682213 -0.201497264564795 0.140229659179155 0.356741481023154 0.279844547508011 0.370991288737538 0.203916901723289 0.388339088688405 0.398540234917603 0.274348677797096 0.375311488431508 0.355871706015409 0.142386200243735 0.355673862105439 0.182448119984894 -0.0629219639529884 0.362622296190936 acenocoumarol 0.0741609972237665 0.323928259902448 0.0954568430355338 0.329829410723413 0.101068731360011 0.174925456307163 -0.0337414287971144 0.141603886763463 -0.0440807697871811 -0.0219901784791148 -0.129990004301406 0.0127917716512645 0.0495709986317289 0.142698265452426 0.131751377875966 0.221919971243163 0.0832417133050787 0.114901858628651 0.251957215656937 0.00938134507371403 0.00901233359212492 triamcinolone 0.0246219132208427 -0.18474404044771 -0.0844142146431799 -0.1673159636431 -0.0887664588398749 -0.118444086682124 -0.0608747583356409 -0.0775470935739509 0.0352936980254437 0.193403668536391 0.0520228554175017 0.0457219768128567 0.0343334021801025 -0.197127362511951 -0.211595236833339 -0.13834954471853 0.135007519324662 -0.119871099577717 -0.192994306157407 0.0829321052605479 0.054087053232729 tetracycline -0.180136417908967 0.501671765339427 0 0.262495411459915 0.275559253209608 0.241299894454953 0.212254101411181 0.294969381124243 0.228305910315416 0.601410356299612 0.0455669379563334 0.400951908010645 0.403687316194698 0.481269898019769 0.466694147147382 0.467906845614597 0.462127937587006 0.474862620937053 0.259060829402242 0.178518273952005 0 dihydroergotamine -0.335507976452194 -0.0809864099252977 0.254022994871039 -0.149832513458444 -0.0871506836384323 -0.286396199927472 -0.171598601108829 -0.166170706638281 0.00460999708075349 -0.0268622339310228 -0.259547280647969 -0.114719209936852 -0.295097378927612 -0.134504506739602 0.0105869417854852 -0.128549578344626 -0.143848814611046 -0.180655289549795 -0.210447967403372 -0.0935073925743465 -0.179161489458073 isoniazid 0.314552210366398 0.399785525242947 -0.384624698007147 0.267107937872824 0.304486591792116 0.291819061468696 0.23172512462103 0.422063910761646 0.424161091165368 0.383412041565818 0.304437025365435 0.463269754189085 0.451950260215583 0.465170047674425 0.35395372026654 0.458804734446067 0.499930830640692 0.414511535372797 0.323812974013056 0.166069756858199 0.430061641803719 tranexamic acid 0.360114281834802 0.618974775616516 -0.459885240408005 0.405064909570367 0.421165282071704 0.132132684120302 0.405255898632116 0.592444023472572 0.319667413908689 0.610410092489497 0.470698624882294 0.627567136533961 0.645404162888288 0.635253688282282 0.627801969218748 0.631369589708846 0.357944237382488 0.600280203907938 0.489259887320625 0.416493581876384 0.640787794181989 ampyrone -0.0215164811205291 0.41746833156894 0.0512830715244209 0.235711186527917 0.291710776670986 -0.118811525126425 0.142704207451734 0.334430241145078 0.274821727099663 0.453393033894969 0.0737226907248391 0.367453947317787 0.328006084143872 0.38339551733417 0.392405286276707 0.40474121735449 0.126962128576567 0.448372235078649 0.431796665789885 0 0.217456075765412 midodrine -0.0242898345247548 0.567090303370327 -0.075810941676754 0.559672245827702 0.523528591556435 0 0.0527423428236563 0.469762414286822 0.436846690800914 0.565115584226624 0.229800410168876 0.351447892869694 0.580390513319455 0.433757735374569 0.414816837504498 0.486502613618992 0.436596689624582 0.40035733409101 0.695042148786727 0.0356504321988581 0.424444329631878 ranitidine -0.0941889719222908 -0.462672006735469 -0.18205986151476 -0.26623489868203 -0.438025221415252 -0.105873963693143 -0.0832299098169902 -0.458545659682085 -0.252205093793862 -0.357673037285314 -0.204290974725645 -0.332294421576254 -0.478771631415225 -0.492252740926354 -0.465760131393841 -0.404422845830494 -0.164417500604922 -0.407925932127252 -0.391192302164522 -0.0182327702669807 -0.204560514212347 piroxicam 0.118049450076856 -0.361465989854732 0.13021299679312 -0.426632248799807 -0.399351353643354 -0.0456412958460978 0 -0.33426594287675 -0.339112465178184 -0.377328475474487 -0.274240048889649 -0.166222885088499 -0.465312202814411 -0.351997769414323 -0.459641881165941 -0.316149158607339 -0.251524045788954 -0.324417814883303 -0.616528124613561 -0.132699490906097 -0.336519626291869 norfloxacin 0.132185423129212 -0.445452766601609 -0.190108666652511 -0.43209289022937 -0.326850125556286 -0.069431459101558 0.0443418137998147 -0.363844087564074 -0.574382311327433 -0.248474207255144 -0.229561497805254 -0.326382430408169 -0.46009977767494 -0.589849729169508 -0.402971974554149 -0.44239272422247 -0.206378314660153 -0.374953165538767 -0.491245772239366 0.0255633403688019 -0.444365438796268 etodolac 0.210885743882429 -0.341592735765417 -0.116355999105228 -0.149209745345787 -0.295190770732269 -0.0444130213486817 0.0479289582253301 -0.335648298480165 -0.202760890239287 -0.367884863714844 -0.265679789805513 -0.305603802864973 -0.383450311198473 -0.281748741298511 -0.364193750216239 -0.353175034077473 -0.279593134950859 -0.335737024802216 -0.342522298949591 -0.0867340904260313 -0.0501984550341123 pentetrazol 0.164281376047492 -0.304618666625335 0.208644731362092 -0.415366578745665 -0.120686006056333 -0.109818169300695 0.0303335309216987 -0.253134881227554 -0.417140979649045 -0.404865216793909 -0.233741127550819 -0.264501243108446 -0.32152249936319 -0.473020577691859 -0.441302993269202 -0.319479662955376 -0.425771935348948 -0.201177604834675 -0.51035571162819 -0.471326182457719 -0.211639300473217 etofylline 0.089060816619275 -0.495919060127559 0.180349504166052 -0.378558429595443 -0.282852909973346 -0.0461705426211472 -0.0161085363169367 -0.390729508302247 -0.501163497155689 -0.505945256947275 -0.374673407140252 -0.505837602176098 -0.426862383248098 -0.499711840049199 -0.568132135877738 -0.41382733857526 -0.433032316217029 -0.430307481342587 -0.430991087164254 -0.200895829513374 -0.373687801391714 levamisole 0.089571713662146 -0.5165233942265 0.244526883459592 -0.466261337213837 -0.515369387758196 -0.145421009019287 -0.318379329690063 -0.633333941261663 -0.493235203059733 -0.642764925729228 -0.384964265700176 -0.599372717082449 -0.62503299163853 -0.668314643533073 -0.668143544078911 -0.631053859088216 -0.314558358328407 -0.623070702648929 -0.695571360779922 -0.162296275678946 -0.509150495156197 tiratricol 0.0461934296374657 -0.368975611286149 -0.101380512379284 -0.208160363708377 -0.266783405956352 0 0.0323496504347423 -0.383328776658629 -0.418623706429825 -0.156668371410061 -0.0236116653077077 -0.0649607496419691 -0.209957474509956 -0.522132147453885 -0.41845071464109 -0.277676386431338 -0.184684530888377 -0.307445607532064 -0.422453964822116 -0.225969144672842 -0.0944542722864345 pyrantel 0.0533253519399678 -0.353092076118275 0.171923716561452 -0.327643977096111 -0.257627918902346 0.0714848241428048 0.135932224849445 -0.250143402732432 -0.276745971015942 -0.314258534026053 -0.146561999934882 -0.309769165344058 -0.262615425002019 -0.413322800165916 -0.376505074792174 -0.408025300867708 -0.162843058210637 -0.379656556080835 -0.387732294858662 -0.291654259401788 -0.387648070504229 antimycin A -0.413780896946617 -0.613223564341092 0.130738267541996 -0.473380924478358 -0.564895674732076 -0.313291745310981 -0.566299343352228 -0.612700810467224 -0.635985484157635 -0.648398192755117 -0.525285309745665 -0.625359795765011 -0.671916029883632 -0.71158769591709 -0.729480889736469 -0.649456780005751 -0.304783294632531 -0.635472844077986 -0.637954192091371 -0.427067016247793 -0.666919580422197 scopolamine N-oxide -0.00111030503706331 -0.400210968526399 -0.125084353032713 -0.284938067198217 -0.313239577792105 -0.0518026266004292 0.0167263435167393 -0.387734278199234 -0.39441327078626 -0.387547063126625 -0.216833161849304 -0.393386982771134 -0.40781706031283 -0.476132969460801 -0.457644439120365 -0.440530505925238 -0.231114505953718 -0.396855722001806 -0.440818924407054 -0.0213404986691045 0.00828790621044615 chlorzoxazone 0 -0.586933040943783 0.236212109725663 -0.567124931746723 -0.532267422508761 -0.219230179705704 0.127826925597346 -0.574167447825302 -0.508485980212756 -0.527082777961456 -0.320652198376961 -0.482626465169425 -0.466464756126061 -0.638951642729219 -0.598377907218373 -0.608615410285324 -0.419769760776676 -0.526814163301125 -0.628778919323288 -0.377895478030072 -0.483081463104045 tranylcypromine -0.302334340027865 -0.507267338736839 0.326901562481799 -0.507654595866622 -0.593547619945726 -0.487813488937521 -0.319714781958502 -0.662305504372137 -0.626582368816538 -0.626830293814677 -0.417351968122963 -0.58686209362233 -0.635576501302009 -0.691811020235552 -0.577389160022208 -0.637595507867443 -0.299507856769421 -0.654235634202006 -0.467994906950916 -0.474418263133487 -0.373419393482448 pargyline -0.154598089550701 -0.674917240309945 -0.110077104274665 -0.579022768395954 -0.671467809009591 0 -0.266892203832947 -0.640206791130929 -0.620337424059682 -0.643132428857089 -0.486334803446236 -0.622317656100869 -0.650007566525471 -0.736756082315823 -0.684694873126196 -0.673114824144617 -0.560655963148132 -0.648794331308141 -0.691963068416047 -0.142733775497047 -0.536530415020522 oxolinic acid 0.0228170466799967 -0.485645295775911 0.254808904712156 -0.478607800701872 -0.28333884195112 0.0175599561801387 0.147557140084191 -0.38738647026038 -0.265041787312999 -0.337620087281382 -0.121162629390114 -0.106532323005494 -0.370381190195517 -0.521331938176841 -0.394265954578661 -0.492371664613842 -0.348589829262058 -0.494193119400515 -0.427029516797288 -0.314025075890907 -0.297210809755187 fenspiride -0.280938596203154 -0.396763526267195 0.140467806932299 -0.319374864173368 -0.421403765836141 -0.117716977734147 -0.0635294512836167 -0.44345110394903 -0.549788200397701 -0.373863203572968 -0.436777197639489 -0.475723152087178 -0.438011604457079 -0.441422848257387 -0.447055511898529 -0.417782609662923 -0.180185313007057 -0.379582179521783 -0.290828362219114 -0.356970794468896 -0.369794804472296 xylometazoline -0.303817097939834 -0.589967155242479 0.0654138944716557 -0.514268741840716 -0.439705368707672 -0.259169864029079 -0.132820332962583 -0.466773513139944 -0.441760741252111 -0.595490904204024 -0.375240775842027 -0.5593876554028 -0.479164673646024 -0.654199861041088 -0.493493417163903 -0.490225589274339 -0.212701754079466 -0.446974918487313 -0.55296186781193 -0.374661216168152 -0.291174165480878 hyoscyamine 0 -0.402691041694329 0.2674512525271 -0.274219600408677 -0.366808871616302 -0.210192071098318 -0.16895453562275 -0.432551401741762 -0.276700504779459 -0.42060489358869 -0.263295684122987 -0.264962487048796 -0.410384932718613 -0.444426679602613 -0.444806504042112 -0.417305310188269 -0.330630192556722 -0.334423519522583 -0.491565453809744 -0.282561187180685 -0.370357854056043 ornidazole 0.0269360560421037 -0.527463319613508 0.157055876563762 -0.464350852699242 -0.291595258633165 0.102478614628656 -0.160969573841334 -0.420412509539416 -0.391746236276461 -0.480243554751525 -0.222923741409776 -0.32807000410441 -0.52427369724434 -0.589402009569043 -0.362861463782294 -0.551843374927978 -0.172437107329468 -0.381757214359572 -0.570275849287868 -0.237742413655837 -0.350142505704109 alverine -0.26635188539569 -0.0928124747822208 0.143533239139746 -0.0901514508574452 -0.0759841482102446 -0.329476151776834 -0.349163636875259 -0.114301225644027 -0.16448641173324 -0.18813535555333 -0.123750976893632 -0.243612819281763 -0.239701184047562 -0.0351135214220093 -0.154004915667746 -0.130623602873908 -0.0716429860230705 -0.093777093468338 -0.194553047303773 -0.226583795128541 -0.266859341387466 nimesulide -0.0805190954656966 -0.296634080348491 0.160873648039126 -0.269997843777937 -0.247318303172398 -0.139625494393937 0.0234825663108024 -0.476783595834917 -0.530518716402649 -0.328927525749947 -0.219567329198334 -0.444865191113076 -0.267230788977078 -0.263781943332611 -0.417458535252758 -0.387491688628156 -0.134860011979256 -0.260168672053408 -0.0285446518881905 -0.287441848763959 -0.272850887812067 flumequine -0.163466203668362 -0.0162909451379873 0 0.110480350739423 -0.10420052191251 0.00294236430649771 0 0.00581539513249757 0.116499441380432 0.0352938563200459 0.128154510544674 0.0341762751907359 -0.239023107930789 0.00978326337038027 0.00964172813730585 -0.161540628914265 -0.0403076280459574 -0.125623805479643 -0.0765252602315948 0.160962463348059 -0.114073425015197 gemfibrozil -0.0216201733087255 -0.29122375473649 0.189552990385418 -0.0992207085429924 -0.120242885211914 0.126883214748972 0.0607248756998734 -0.242085068722243 -0.427548102196027 -0.30349318028728 -0.201949414656586 -0.362921526800692 -0.169884951722642 -0.354186899713158 -0.115957869606216 -0.338690390020743 -0.0688519426544781 -0.289105451661622 -0.526232135133942 -0.144246575353316 -0.306287326909196 oxymetazoline -0.236391825967671 -0.394142069684362 0.107555225748573 -0.372635307859649 -0.469549403224446 -0.313093163832547 -0.0850132105001774 -0.413826951585149 -0.253377521509044 -0.273619465001596 -0.258491878925889 -0.377693412124191 -0.499990753676089 -0.435171979567818 -0.193963937482732 -0.532693317388563 -0.104372029971958 -0.388097902596403 -0.525594454694692 0 -0.298360204296144 chlorphenesin -0.305796313737579 -0.476333510069423 0.351959847866981 -0.109878411598796 -0.34812683455431 -0.171680602131446 -0.216173137653418 -0.487444007646394 -0.431052219897604 -0.461515706558967 -0.356483842737564 -0.263593451009992 -0.481098017201721 -0.436674071451027 -0.523617583548283 -0.503392477617636 -0.098953028937999 -0.502509743722737 -0.267221839740679 -0.0988289092815426 -0.272559534095158 ethosuximide -0.0976164423433342 -0.42309004985478 0.157786558833629 -0.0888656033355609 -0.301221867013714 -0.0958892440861763 0.00314805802568946 -0.39853954807735 -0.31299577937108 -0.269166461277546 -0.334806786600822 -0.298131959998234 -0.426776527786371 -0.338515296493075 -0.3380072098372 -0.292960039107976 -0.0334440189128542 -0.423803820113577 -0.322703064671096 0 -0.00228674799380377 aztreonam -0.218616283030143 -0.171772980130123 -0.150365689734851 -0.00908146591179719 -0.164994372424199 -0.0380238351141721 -0.151646077132184 -0.16611419403108 -0.164545944212581 -0.278005592200653 -0.164555459102904 -0.151168464053077 -0.257270518375075 -0.208490231586483 -0.383564783789583 -0.283134114678265 -0.13544024792649 -0.201354980779873 -0.217053646019798 -0.154525066621301 -0.0047653408546294 hydrastinine -0.00781619957684201 -0.212023059325544 0 -0.217325766577191 -0.106934096060729 -0.114987652785126 0.13617165962083 -0.109533597647853 -0.039433121502649 -0.217029169156385 -0.0819742892798407 -0.0572187900704591 -0.0801669997366807 -0.125790784685791 -0.0966301451421686 -0.232305421199041 -0.0600936770492736 -0.124597977702051 -0.197869982162033 -0.0669785891449459 -0.166639521331324 tolfenamic acid -0.326600529080163 -0.266869620512912 0.189354460118551 -0.245600873432509 -0.287154289397711 -0.222692560749583 -0.205516440825845 -0.399420667563303 -0.324710253132827 -0.154125926775562 -0.354109525358148 -0.447212103556129 -0.43852144194266 -0.316278860525975 -0.287917184860764 -0.411900047942548 -0.0915164044972958 -0.233355581929725 -0.296246282559607 0.101785974245424 -0.317528060634589 mefexamide 0.0783319185315024 0.361777695191339 0.135446059900279 0.342022438550324 0.132001545402659 0 -0.00412358854537521 0.209307970757925 0.215712470054293 0.277744861941184 0.169163568394527 0.3450081661965 0.254318597749386 0.423622863983165 0.279192289877101 0.283067832273213 0.318889825513043 0.392816632849741 0.384282348485609 0.330637207179989 0.144556077870866 nifenazone 0.0897652755435715 0.0710869022222247 0 -0.00287727501860898 0.0496622808117026 0.0617782442969427 0.178736499961962 -0.10922280533276 -0.190279693587875 0.231259846281739 0.0662121308343612 0.204191754608734 0.198035038792898 0.0864175607029905 0.211804408281827 0.194261109426242 0.0231972864087825 0.186596085114715 -0.110825614378261 0.0254642981202626 0.131519105687227 metampicillin 0.0883016862931278 0.414772209112073 -0.174417778089605 0.457041057365496 0.420417003593159 0.191158039511208 -0.0745821463880943 0.543675976688829 0.280452612809523 0.38409335412373 0.172192567592517 0.375267173543624 0.429336665735358 0.437458460424046 0.470116370366577 0.428878549069414 0.248670045360138 0.416545565646388 0.562022838262696 0.155841606571118 0.358925504394159 mafenide 0.21039387097759 0.0560098278592912 -0.302597530631302 0.006778049266962 0.0572188591526655 0.179505760514022 0.0549463256264971 0.223367108790078 0.204753047875788 0.1741409370341 0.133885580010204 0.236645416204292 0.0204543424883391 0.338846771173301 0.321742547314342 0.0884561400804751 0.077372923470591 -0.0457631988503908 0.171563660268401 0.0393747262794212 0.112890968790475 iproniazid 0.0139891503157369 0.328259565893123 -0.220948956861065 0.148193413277716 0.19458490727834 -0.0899137154423187 -0.0720861635903691 0.252863239015621 0.107719634618469 0.497104277498259 0.234706752028786 0.215753964891406 0.347356659904349 0.509121045775892 0.439340731697633 0.438489397106077 0.320242187197719 0.400129652616294 0.540749541859461 0.219731773746001 0.23297085961454 cloxacillin 0.0683547713237767 0.447728799071523 0.0643415502495248 0.397538886469339 0.391239156549545 0.0922970391303655 0 0.445691129713236 0.15573841698727 0.398753736045122 0.359692875705376 0.419482347171921 0.23415433178996 0.224938227519383 0.318959588369125 0.237914964109617 0.553260811224442 0.469544282955653 0.481955470653502 0.263181420885693 -0.0971009902314427 pentoxifylline 0 0.528469578915976 0.0942532396686124 0.421635723509694 0.260457153244263 0.252727517242948 -0.0621864062053711 0.447664855094676 0.371959355816534 0.447744761043911 0.212936124477401 0.532819346402285 0.473573365612105 0.502608005420778 0.584323143743797 0.457081786011323 0.37510206865274 0.349713607241219 0.484773374433074 -0.0818950745287861 0.00294392393368348 meclofenamic acid 0.0674466460881752 0.268945588132703 -0.0142708429236763 0.22655183108881 0.342239559516358 0.300280569138161 -0.0493834768648919 0.446426173305372 0.0996665653667281 0.305350316031439 0.170192547763763 0.340544193779004 0.355314394599611 0.336324668892691 0.36978725330568 0.336990704788651 0.164093014498688 0.350791413005719 0.269496519724071 0.0938039984896077 0.216098248302638 sulfathiazole 0.232188526930902 -0.307886335800794 -0.177045404400395 -0.253544558292281 -0.0373400760052564 0.180815617026196 0.213067183456891 -0.121075457027328 -0.314496673650098 -0.272462208495882 -0.103641407956297 -0.0557485389403146 -0.164578610900567 -0.247853486122945 -0.26591408292876 -0.347057536125256 -0.425519553529632 -0.264998149817611 -0.38524320561356 -0.339240836563195 -0.132314996567327 cimetidine -0.198130831703731 -0.0582482586532453 -0.20018565001971 -0.111219825631888 -0.0727388212302765 -0.0684562425150661 0.256141105611763 -0.0448712903977322 -0.11438452050922 -0.176604558880728 -0.0607508528117112 -0.105681703506085 0.0147734153928431 0.0929620661604472 0.0862518939717028 -0.0916888366778439 -0.102189876084133 -0.164858778301113 -0.11862998795597 -0.0924540139703283 -0.0722815853120326 troleandomycin -0.0383689909809149 -0.537145553655688 0.118371758864575 -0.317669535688676 -0.475111922295937 0.124211897153057 -0.415057482194964 -0.493293107557091 -0.475191878509283 -0.256266176594701 -0.453753165075852 -0.376155723646425 -0.473316224487631 -0.48229821442536 -0.471604834588825 -0.4420585061072 -0.117951726881661 -0.437152992080922 -0.412931001516758 -0.399111560977186 -0.156009575558178 naphazoline -0.0681100069099361 -0.266069414743448 -0.0526970876481019 -0.211810630595137 -0.208440289838076 0.0885180914949646 0.131465173112026 -0.222487626186873 -0.293293449700533 -0.162871893004415 -0.0876013774677542 -0.241023364636634 -0.266954747882007 -0.421171375406708 -0.292923375030664 -0.301884094739988 -0.376839545078461 -0.2174598612137 -0.309730751084168 -0.292447965744943 -0.0392689026426472 sulpiride -0.00476970822354736 -0.108804987109251 -0.210163069216716 -0.284354154273141 -0.217254077541382 0.104025586700634 0.297866391971532 -0.151930531007066 -0.1044606701675 -0.184009558183976 -0.0563753813296861 -0.0941846169031082 -0.153727103868798 -0.256254490913882 -0.0770271432606755 -0.213291444800817 -0.116843800171493 -0.0366286166541643 -0.09408474900485 0.0259170237884169 -0.0992654978673698 minaprine -0.0305357981197623 -0.236457314592147 -0.0905969326665565 -0.260088434172247 -0.0749875777303382 0.117945369425271 0.0968291966881847 -0.197338400511238 -0.275032336527174 -0.0893740308542708 0.000221384202736419 -0.172643674775221 -0.237092800462509 -0.174762170960962 -0.270200084105771 -0.159411629584221 0.0291144680208062 -0.223116505351912 -0.268634097431042 0.0788023218234724 0 cinchocaine -0.392395832758339 -0.508463681664001 -0.116328708546086 -0.37718599650276 -0.531040778390905 -0.471106249155339 -0.186608613959305 -0.446022396433387 -0.285393920009897 -0.447749970582554 -0.257823573817225 -0.499518956495295 -0.500652194938378 -0.595865288110418 -0.496556253331414 -0.540691259303602 -0.369090528348933 -0.514501582439717 -0.565350356062427 -0.347147134055999 -0.402646796290322 amiloride -0.219334475214458 -0.384876844238744 0.0809793434188835 -0.178957981183067 -0.293658710118685 -0.398012299241119 -0.270336899809198 -0.446050313612391 -0.211462846789296 -0.289602722553752 -0.0625254093501648 -0.435457022105439 -0.417636170402765 -0.392672420983437 -0.381268492208702 -0.311935349827346 -0.304282744333787 -0.367258457549628 -0.310332630523791 -0.300713014953594 -0.247605366354542 levodopa -0.0775690987825244 -0.259207741958583 -0.162381868519905 -0.00814042096077486 -0.221537460787025 0.0361627615215114 0.121597369533328 -0.269882345164839 -0.193676993779999 -0.227397947305583 -0.159868234369352 -0.216277107397023 -0.310541135091793 -0.348534510245941 -0.212479800637461 -0.21926377057524 -0.0562480980401394 -0.126376432988012 -0.0957837657693229 -0.219296400728045 -0.0836150888614523 doxylamine 0.357070182283488 -0.485776571513119 -0.113060473706315 -0.563061433254985 0.0895749280099526 0.387914064204919 0.506278335752732 -0.220997126335035 -0.365378434940085 -0.378533363557342 0.0198664086040763 -0.1540137003436 -0.367255112699952 -0.420570050585961 -0.471047998724599 -0.434128961694595 -0.499811647210513 -0.428878392664022 -0.388294431203151 -0.402619132253289 -0.0237867321676416 pyrimethamine 0.220886248211358 -0.454692317936631 0.062646806701812 -0.404652072359935 -0.143462153125836 0.140926566675866 -0.0906672586523971 -0.225610137749008 -0.359432682211573 -0.210636772586654 -0.242656569713152 -0.26422686062511 -0.27043892334161 -0.227620833105738 -0.469910882299194 -0.0979217026947494 -0.279146704820605 -0.34161525275828 -0.381035376854142 -0.346763239405882 0.0115299692543765 ticlopidine 0.00848038662008431 -0.218048421944943 -0.195940290245699 -0.293357640530667 -0.165534064960919 -0.19379115714765 0.112949125203637 -0.200763786185365 -0.3122393009609 -0.283824989907797 -0.18245555714689 -0.225092205933155 -0.308294567503974 -0.369919619533205 -0.476255289211039 -0.302566818728352 -0.173840632427233 -0.293556590714351 -0.225874502804737 -0.229812862775499 -0.0789144100772739 oxybuprocaine -0.124791322460256 -0.319624379845591 -0.117233974510162 -0.427162246351945 -0.324859522874807 -0.271717111929076 -0.0843415216883439 -0.484891789634656 -0.418402547868666 -0.481642487278939 -0.252374053872398 -0.32635244079865 -0.589771486293592 -0.404179372644471 -0.508295052023246 -0.333939668043699 -0.491631067029104 -0.304712999839669 -0.520008568717054 -0.150918414337957 -0.402819499333055 miconazole -0.504390676866452 -0.361110272716733 -0.0857080020106505 -0.257303075154936 -0.397274163544546 -0.226589962078935 -0.470864667461892 -0.473654626165502 -0.433060699279422 -0.483322257164932 -0.302353081180131 -0.463310475861263 -0.496921972911397 -0.439462510833036 -0.66723540132089 -0.473925080596642 -0.321929418652565 -0.495496516436529 -0.186043013766141 -0.46082296193406 -0.314782150841178 prednisone 0.215432535278818 0.0192729269301365 -0.111722077027679 -0.0171420403358332 0.23316742522408 0.217217568090589 0.0359463071530841 0.0761974914071237 0.0640580380043955 0.231847305786006 0.180953319199983 0.279132919312025 0.154440450010066 0.00906980746327313 0.0952457154001072 0.238932583505389 0.0152381497262718 0.123883080430329 0.0320495821421458 -0.1168159583416 0.228422473359695 amprolium 0.338639376091643 -0.428886672602303 -0.0395186236125574 -0.365026014872161 -0.0628701286468468 0.118293366737273 0.06777388504833 -0.336747984301973 -0.385621454407493 -0.464372177657974 -0.251711934308351 -0.159324873195064 -0.281719073518989 -0.41638673903066 -0.28354193485572 -0.408795576377005 -0.443275351758187 -0.295325730796649 -0.648977139964973 -0.351003763840869 -0.441388584509069 idoxuridine -0.221596696035001 -0.103152479883757 -0.197622830428878 -0.275781586831609 0.0188576548513331 0.210446048501395 -0.0513209079186684 -0.00452303136998686 -0.00825358214078653 -0.226033117143438 -0.180834849675525 -0.334852444876706 -0.0912137381217057 -0.147540673629388 -0.144388558690548 -0.259175937156164 -0.333393144563453 -0.250966608806089 -0.213332125589296 -0.305697471903181 -0.151491892359854 ethambutol -0.094395645176626 -0.149954828130792 0.103281454296028 -0.251624861197996 -0.313004699694579 -0.0497724462480446 -0.0413811391439431 -0.320914488867216 -0.179618419167838 -0.186803396666996 -0.20744252144888 -0.332137346303097 -0.193896887057056 -0.266711168770774 -0.238572592496613 -0.264382055430237 -0.0587628287573905 -0.268149642391009 -0.254900055134911 -0.114266621716647 -0.221235174340872 hexamethonium bromide 0.0483765548840682 -0.581473225472173 0.0819909283135115 -0.50326119128479 -0.523962662662184 -0.00987446657702941 -0.103245038330286 -0.57367272769974 -0.45426788481156 -0.467442604665609 -0.330126671493721 -0.431406128913822 -0.603714359323024 -0.639218781295831 -0.549842932021854 -0.592920676127031 -0.406718407046253 -0.478495359413301 -0.405522981108653 -0.465857047381417 -0.183079871168739 dicycloverine 0.113575626893129 0.151319098535595 0.13499970305914 -0.056492900210077 0.0364557091742753 0.0983981660862276 -0.1479553698986 0.205338699351065 -0.186735142300164 -0.09984278560863 -0.189951190638461 0.164097785971721 0.0672821325414581 -0.0710370407704362 -0.0598847992967605 0.0298988775852325 0.0189649708150069 -0.0352801190949449 0.325754094251648 -0.128641932804228 0.008838216087474 oxetacaine 0.0163738510571966 -0.554130622925679 0 -0.546819776142582 -0.348693959277359 0.0302194294313933 -0.193605228278802 -0.534867865403114 -0.481971686145429 -0.506722449257165 -0.348695311527285 -0.401493545287044 -0.589765512774297 -0.626851683770801 -0.627068060180057 -0.430524516296707 -0.448118148682648 -0.591457088285577 -0.536078651425895 -0.361208029672567 -0.3046889528138 isoxsuprine -0.109769114001119 -0.0928635927690833 -0.0193532309462532 -0.15428661542251 -0.0726176487127972 -0.178237938923537 -0.0922451006323302 -0.0697176254667105 -0.277669315184804 -0.0333782184575266 -0.187340340109079 -0.0279010304012464 -0.142215585496575 -0.131876409500925 -0.107182905708539 -0.139126302289189 -0.233790495821608 -0.109349281412803 -0.143835752573779 -0.00887065179840294 -0.0054986227132549 hydrochlorothiazide 0.228767859477649 0.168643091313876 0.189148132070942 0.17676484843728 0.0424047019978461 -0.0788919117116449 0.112891255497601 0.320452965768717 -0.0353349820565969 0.171788382590525 0.167728033783171 0.124812354261867 0.237576662056652 0.20296896250013 0.1273076034953 0.0448814795730192 0.183211708920002 0.173610812991291 0.382327347328269 0.0978482188478839 -0.000690639344637778 captopril 0.22869441568197 0.0484679380982174 0.0963686079445735 -0.0552357623804142 0.126971378548425 0.263027977779171 0.140822729867304 0.103243267974571 0.0164511010528411 0.00135506561844581 -0.0227219718590324 0.210796798216507 0.00821617790709845 -0.1089742890739 0.00121052823989295 -0.084913695286108 0.028722585038925 0.0465018908428556 -0.00516386316995082 -0.318431782342689 -0.0785202268914489 phenazone 0.416915581291446 -0.0128150955866103 -0.166993546715459 0.171209321170359 0.358458040905498 0.448428937071333 0.370356948370023 0.365963755264042 -0.0191092641547842 0.0726448018292707 0.260025410302132 0.179426808251746 0.348481298754597 0.16873335822271 0.0671772341731492 0.0393095830405186 0.00247167351349668 0.022572358213728 -0.2647416028715 -0.268932096620332 0.292700435612512 diflunisal 0.258291296932298 -0.170983246081098 -0.12899853891073 -0.0202403228853478 -0.0625869539386548 -0.0962821145285482 0.156460487602609 -0.176546679723644 -0.0924946881613117 -0.137112388811947 0.117714416011669 -0.152676175230278 -0.173725833324749 -0.0926034108692123 -0.199949976183337 -0.099721082662835 0.00612928195920126 -0.0144104967991644 -0.318642665979977 -0.195988019506621 0.0401214783191967 amylocaine -0.0874597888322056 -0.0423857388668053 -0.169900378616292 0.00245543888301656 -0.0132112236106593 -0.00113024470537539 0.0915771515332066 -0.0413672776622523 -0.15033272288418 -0.0631754365699739 0.0213856807718728 -0.0835720261520122 -0.0535338594014149 -0.101904549133603 -0.0875449051920879 -0.0977720270675419 -0.146501527592421 -0.0531942405713719 0.0296232231361469 0.12438645588685 0.0518771236853213 pheniramine 0.17361051365363 0.0210214982771769 0.183635293225757 0.0105520954018414 0.285592587200284 -0.0140553568087731 0 0.170757745046925 0.0918745042109067 -0.0215476775394255 0.083326725949136 0.0631066940780932 0.0672977510452006 0.0760156572344887 0.156807934308631 0.162818887184175 0.000397717576216372 0.0562102483930169 0.215151226417925 -0.108162288178993 0.0500642108273423 acebutolol -0.298889206889835 0.205060932307877 0.17921830270896 0.19964568509856 0.147321076761744 0.104402389521512 0.0259475691557465 0.160791659363478 0.142961203686361 0.115125145482288 0.160851015974343 0.15119544007821 0.0383021848214474 0.166007626738989 0.273196172525056 0.159454408739193 0.142059163569205 0.377622056406076 0.205684195658149 0.0528142834740002 -0.0627052812711705 diphemanil metilsulfate -0.0842912812965519 0.0792078619153485 0.0245206767958537 0.159425137133891 0.115213838257173 0.0708113652540258 0.155740263041524 0.0478297264313777 0.0394958900398701 0.0180941874829426 0.268841003311922 0.0506009585884564 0.155381522231886 0.218315928560014 0.0420057256138714 0.124024591588573 0.199467577887144 0.0731197745081448 0.0511410853897119 0.0485235089276072 0.239598791165498 sulfaguanidine 0.308307273851654 -0.301570422592761 0.259762298364266 -0.37432509148961 -0.0693229720316193 0 0.174743246445421 -0.187562370685498 -0.242536517127772 -0.28622631973052 0.0989566818334559 -0.112500548606522 -0.196484567547379 -0.298969421538582 -0.238529381025121 -0.27614144978104 0.0462826374563593 -0.242525197864599 -0.299942777034776 -0.101049673080484 -0.0820183387430989 minoxidil 0.115286206044008 0.112157700580128 -0.13685756931162 0.0310943078520237 0.197305760802618 -0.0436931756371706 0.160364552939025 0.25573909260039 0.00907857775983472 0.0278374440702278 0.251939345016452 0.15126522667306 0.240266203265688 0.119789273224082 0.203065297601422 0.154786302385005 0.343082763181702 0.215273586849196 0.213624139733832 0.200278779355143 0.108666027337856 4-hydroxyphenazone -0.217361418189603 -0.0212610627949195 -0.0277562249624316 -0.226538026453212 0.0262936335444383 -0.0228278872055362 -0.00488855061140511 -0.0949643893380126 -0.108333463766561 0.186791492447192 -0.0172288286871737 0.0112202128265215 -0.0310513863528185 -0.102994499502663 -0.0818429701710984 0.0534862299734367 0.0479135341424703 0.0729553035541078 -0.0683640540465661 0.102640402151176 -0.0694212758252815 niclosamide -0.58615965842396 -0.461518266151267 0.121101296045015 -0.214147480279023 -0.23107109942915 -0.129005860179805 -0.527713847434938 -0.371404578872354 -0.604311682900042 -0.634179432840811 -0.562363075839539 -0.555047924796517 -0.528398495358675 -0.661802146940575 -0.698864796181524 -0.289235258142859 -0.355676578010068 -0.504299421779931 -0.0588779711460075 -0.590601460011216 -0.368660374286687 lidocaine -0.162946410612098 0.254503625452142 0.0223683158561679 0.268638175555359 0.0786669562818501 0 -0.208791936495784 0.288385914116885 0.0174887434026096 0.245724500753035 0.0970828755753046 0.151528662032372 -0.0409731050743859 0.0649138258982554 0.113789639502383 0.156057122256108 0.131084529913604 0.0327232472348656 0.243574778436691 0.220706770648137 0.158828842039979 tolazoline -0.236864798803162 -0.228158642365572 -0.138130855124826 0.0179797918753931 -0.177714448335015 -0.294070933672278 -0.0343461382526262 -0.0559401633353388 -0.149783205888005 -0.197276459565846 -0.0759980216730815 -0.288484691856651 -0.24635258891858 -0.15902418548103 -0.075719588485345 -0.239734949408364 -0.0677824532386467 0.0063087593498658 0.00306186888775872 -0.188251671447464 -0.0138876775763647 tolnaftate 0.0531303356042821 0.347729312341059 0.0672040755180759 0.243944992455557 0.161716350975323 0.151797888271646 0.0859782600150795 0.17096415792432 0.298020186885308 0.358194228414706 0.150955819800547 0.39781154822861 0.245742183049398 0.303681070625255 0.332653255947363 0.387130870638061 0.176298474592854 0.378508236881633 0.276906672519955 -0.0252291766820326 0.270051226640331 trimethobenzamide -0.100242174929373 0.553098917611082 -0.154065929297899 0.436703655808107 0.475929562596706 0.121059875788019 0.465862399844319 0.54522859532409 0.368609080544921 0.543540947030122 0.398522487282952 0.5296649911721 0.659634875263274 0.51203898526005 0.47870276078824 0.548591725039767 0.222068464826447 0.422865142074581 0.521757502572418 0.400636732424908 0.522050655195158 metronidazole -0.0555728514038789 0.504943533556977 -0.115993334219043 0.435302561710231 0.398870802306994 0.0675004365274354 0.0900172920098842 0.519551903103281 0.529101152130802 0.287765951282126 0.188451768891285 0.472144631793921 0.462345952691138 0.428854719699414 0.519225653856168 0.314671738723543 0.315438486251572 0.233755232636821 0.579149307981243 0.222590294849966 0.347162789250686 khellin -0.169574202653788 0.276403361303378 -0.00276892683040133 0.542845800199209 0.255788689466506 -0.210025842768855 -0.0476841891118693 0.341593283485909 0.202056759682489 0.291615609086034 0.205571310081897 0.32751827163983 0.234239066746559 0.263451016962511 0.447723263481023 0.325664463924943 0.247642200456349 0.250374785946711 0.463791656312827 0.265148199698026 0.356782355263353 apomorphine -0.208287362962384 -0.276006735989203 0.228223054335594 -0.316294556535971 -0.42989161218048 -0.256082806637142 -0.503618589092306 -0.388688558599666 -0.347145958485594 -0.421666252440062 -0.374358034287596 -0.544046108263133 -0.492396056880184 -0.506214691536847 -0.531360330352076 -0.129129172700207 -0.207281558752146 -0.452778838838229 -0.304591506166141 -0.137907397811366 -0.370170267732472 naloxone -0.230463385771427 -0.309774688972173 0.0150099726435621 -0.423219522945641 -0.325017943121428 -0.148218789540524 0.0813781911884866 -0.50064553554399 -0.275340948345542 -0.393986707576797 -0.337570454297649 -0.372744695201391 -0.477393155543833 -0.275344381756586 -0.437698417497344 -0.321734710260628 -0.29133001596268 -0.312253925727738 -0.344421568051511 -0.135405964246853 -0.323567689137193 bromocriptine -0.421305137759102 -0.528114288100448 0.162009537943227 -0.342949870011871 -0.541979929151393 -0.180670275026823 -0.207940002137496 -0.605288895213172 -0.434776762657033 -0.498946345647026 -0.350916288519891 -0.592352218901303 -0.608767758861103 -0.603365021288899 -0.52980966765762 -0.607259509667677 -0.41712646233159 -0.562667656051789 -0.577435197631298 -0.432684219649528 -0.484520765287006 glipizide -0.0746562601104739 -0.0801856725815521 0.17405737508481 0.0223695232085625 -0.203442840652594 -0.0358708179161275 -0.196202596727548 -0.140961437662375 -0.0369274934251908 -0.130772780281516 0.0644868327749671 -0.020802466572974 -0.216710420578157 -0.125377034122574 -0.13601839175511 -0.0834154993364532 0.0910148855200997 -0.0609510735133569 0.0215171888290566 0.236997143509444 -0.0951132311274544 erythromycin 0.103175492436588 -0.118587010517637 0.176503289359988 -0.0914531228267628 -0.216170143786366 -0.087203782342222 -0.0318060773748279 -0.237448182184986 -0.243003723208452 -0.173059389396516 -0.056054093815033 -0.226344832164665 -0.0217930640027349 -0.0314250653980377 -0.0559494439179411 -0.044883204070723 -0.236028442392969 -0.0666727301210494 -0.0411594503741559 -0.00848614803524773 -0.109369763330379 cotinine -0.270838004578924 -0.249235873219442 -0.113593208678989 -0.27281737601442 -0.271826714137754 0.0880288233691315 -0.0767614418959952 -0.369657920658047 -0.370887640354343 -0.323951829552571 -0.343404381991499 -0.398033103094797 -0.382953765040008 -0.377688614853351 -0.260128986526474 -0.468264409356426 -0.204419396699292 -0.298286090245927 -0.25687874012586 -0.16680041899394 -0.160723458888373 zimeldine -0.45634361515848 -0.516076972926065 0.163419006724495 -0.45279215849129 -0.548928927616786 -0.419002723931523 -0.379390723512674 -0.579041866115455 -0.327825418322372 -0.456478029231996 -0.354447151769857 -0.552040302077852 -0.555937582107472 -0.598620307903018 -0.584098288937599 -0.567812139571077 -0.459028965636495 -0.538018617632656 -0.576888348534602 -0.25985094335476 -0.544549880439402 amoxapine -0.493032275184097 -0.464303001783156 0.193876521393761 -0.456020650380491 -0.43908673061316 0 -0.155126794421146 -0.572036456155089 -0.567511291196738 -0.64493862273555 -0.500267673734021 -0.590556960349839 -0.527747607184056 -0.64669427605155 -0.678644302609626 -0.59382628448466 -0.469273322355176 -0.56628881429791 -0.64553228278183 -0.418697285562278 -0.475688325925344 metolazone -0.108061713058016 -0.0309937085388693 -0.134252290160549 0.164680211276779 -0.0805838247337764 -0.307224150983821 -0.0902905574380158 -0.0780512375237896 -0.0869774542487117 -0.248295006889898 0.102625320001818 -0.229516537555497 -0.128057647845756 -0.00533340713357644 -0.00578412675590227 -0.108888808854221 0.0448797873148056 -0.0036252496110062 0.016904759224107 -0.0839677868950745 0 metanephrine 0.0905166671825341 -0.370301556843956 0.0603720341074981 -0.11909554133071 -0.148799002859201 -0.245896628947493 0 0.0730003426613228 0.0209997667033414 0.0442607615116593 0.0219371912235914 -0.0453488537577105 -0.288720806936257 -0.236004777434257 -0.205554919256839 -0.288867678834515 -0.417523696458637 -0.254993501234447 -0.324630533661817 0.0353657767047009 -0.0841216685232183 loxapine 0.0237159587009275 -0.0175155642690561 0.129040428866442 0.0314221973148118 0.0705425848321641 -0.0111092965923732 -0.113315998438957 0.0735145551769694 0.00745405819723211 -0.0661717265743593 -0.255172972372804 -0.204496222206208 -0.0203493131678223 -0.0117014861702213 -0.0314224023377944 0.0940136999816733 -0.138938537315262 -0.288771938306905 -0.0242081890427639 -0.188264170101337 0.0357660870782373 dipyridamole -0.589441325742145 -0.582929106152663 0.0262779926225565 -0.428268269791621 -0.601297892988431 -0.229371732587176 -0.353050711834926 -0.639582191385578 -0.531105681004009 -0.433342199608155 -0.509982206498705 -0.524463661799457 -0.598415049719234 -0.621206432717735 -0.65006122800863 -0.590722828591623 -0.339524519990921 -0.524509813677301 -0.528221519108891 -0.324480322082088 -0.44877605387922 oleandomycin -0.223793577802155 -0.287778488757679 0.169392520728348 0.0273718427233782 -0.341250490322449 -0.0737686079080965 -0.0610655329472043 -0.379953324969431 -0.0559708815962115 -0.11086516257007 -0.202779476900408 -0.244768562163349 -0.303051621028315 -0.325461255260743 -0.189995649103328 -0.291343600597353 -0.0662946521004898 -0.272058053312258 -0.211417555384364 0.0417607096713579 -0.278129996378579 edrophonium chloride -0.144227640905019 -0.259365636227472 -0.257188376148542 0.0176407067556863 -0.400904159864032 -0.0534320517218404 0 -0.235718646844611 -0.20865791293786 -0.432291572742305 -0.092714718667871 -0.365121566939093 -0.436630377728752 -0.239269599017565 -0.276163300601408 -0.347482389955159 -0.171703959855085 -0.543612632336421 -0.390245441947427 -0.0657601142136239 -0.418816891101876 azacyclonol -0.422413137137671 -0.122943493836752 0.235462491595428 -0.0364753034024969 -0.102721179454399 -0.131733214451255 -0.292183098933917 -0.133973399975017 -0.208213819441878 -0.194944373996436 -0.411421133737364 -0.189610219856352 -0.15557038413652 -0.0615138222704521 -0.0796829040936597 -0.0421702894382393 -0.200648262882233 -0.100800127351841 0.093394304167491 -0.19590083465399 -0.229961140036439 cyproheptadine -0.394968583378386 -0.378074678819878 -0.066295227756083 -0.435581618935326 -0.387019481202935 -0.256085985756414 -0.445452509369861 -0.311061333040621 -0.389847583396478 -0.504540139794964 -0.425788863135199 -0.492189699124361 -0.432056598396454 -0.245852646140006 -0.346417749850265 -0.403904753640673 -0.343284980719572 -0.32249563745567 -0.2619873582652 -0.35297521715874 -0.0255267951893276 ciprofloxacin 0.271847193507327 -0.0470095472590558 -0.107289694346768 -0.0339262192655051 0.113755275265652 -0.0414302744430989 0.0943037332828419 0.0511200259145583 0.212310603212924 0.180943449237563 0.188978674017447 0.00477335227520299 0.0496273501197764 -0.1322237296126 0.0870496387422246 0.0637109460447015 -0.0206523653155012 -0.229009202498005 0.0941662427303532 0.194999778796279 0.267224466110693 dehydrocholic acid 0.0178844193288395 -0.118280231739058 0.0429761591900635 -0.132627587482629 -0.0482842556769979 0.0632719066461416 0.0999165442114364 -0.0561593499816432 0.0645793102619307 -0.106975894798122 0.164852136007143 -0.0944285853993576 -0.104136995174323 -0.127757155560445 0.0200753267747461 -0.118404725713984 0.04585274619573 -0.114852723697413 -0.0903109435474693 -0.121241389612445 -0.197775526238547 hydroxyzine -0.129891134941051 -0.102597893920266 0.122066270555672 -0.0628515425600291 -0.0940044430592182 0.121657383782634 -0.0989449159064052 -0.20401854996451 -0.283839372723659 -0.282639746959026 -0.159481939408913 -0.0897521228936536 -0.0891394272262933 -0.264131727402779 -0.244561332174798 -0.097310836654129 -0.107308738912654 -0.283487625630093 -0.13085333955579 0.0842885115320337 -0.454093339334981 chlorhexidine 0.0566874088350844 0.296873695831786 0.030068522039417 0.0403279993222541 0.202354801902602 0.124374511086584 0.163935963843648 0.168222964179452 0.0905040813385288 0.0766877770893328 -0.0226593025868872 0.267655670774154 0.463674608433539 0.0316003057430619 0.0162706470291025 0.103234109822823 -0.148184626894966 0.0728354265068436 0.403420927717477 -0.198616910756543 -0.114340959701678 midecamycin -0.364115001770646 -0.230779946097117 0.0743810900865361 -0.0689575949407306 -0.174016829128324 0.252486777182495 -0.378971695986438 -0.0811562757409401 0.00692941789339619 -0.0299608962902787 -0.17938903984266 -0.136494614578092 -0.166444978037074 -0.18196951708143 -0.2864742513044 -0.265675710342471 -0.148971540415834 -0.156613064524762 -0.202859115945112 -0.119334451308835 -0.335217928601952 moroxydine 0.262046038993564 0.169845469939636 -0.0607932094847108 0.0365290547637345 0.283595557077978 0.133593992760497 0.262496631528653 0.256497685599696 0.196953940213728 0.326668346169882 0.188910984214429 0.115052855517115 0.183600586171575 0.25897645135362 0.142069833818626 0.170770393081488 0.0448158126625335 0.191079781319982 0.320216452795216 0.193500433240978 0.102351949019686 famotidine 0 -0.213737976381431 0.0325759237689697 -0.107476609834112 -0.300056131639987 0.226225315045514 0.102159395436903 -0.144251681788473 -0.0794584944604913 -0.12372524833376 -0.307964300827488 -0.174900243733453 -0.215350184260742 -0.12685998148343 -0.0228852990688122 -0.204496323260495 0.11918457289984 -0.406482691370604 -0.0562737663194795 0 0.118495286965616 ampicillin 0.292852243890874 0.252949329900899 0.141263646628537 0.081074933463147 -0.0286719845174976 -0.000167305429263673 0.0664914316456791 -0.133284812859861 0.22360905240958 0.246093037486753 0.109208170331706 0.0382593374752964 0.0551681960840281 0.236441462616335 0.14491567450801 0.129365526714358 -0.0184461865334527 0.041521228829802 -0.0978193059106739 0.0325144958588825 0.0479557128852377 hesperetin -0.177505063462452 -0.564863395851926 0.0828453541549665 -0.518917755727853 -0.410546674245301 -0.122422902361516 -0.34481142449621 -0.490300501260607 -0.352340917290815 -0.372952866885696 -0.384870346059054 -0.375492421797959 -0.444447209876342 -0.532650617520841 -0.420992709946277 -0.587937954424266 -0.319056123982687 -0.479065052612056 -0.627291341629631 -0.428567896980008 -0.520052477522518 diltiazem -0.218217735164294 -0.614192801012671 0.190996142060327 -0.60287422739609 -0.584712690007214 -0.130283767987443 -0.253688452184215 -0.493539315318788 -0.384165481689636 -0.529068802040711 -0.439562546485073 -0.482793802600926 -0.636831250290184 -0.681734800700008 -0.644681816017966 -0.666160552970919 -0.503730852217982 -0.612281866639166 -0.679315696505406 -0.340259760900521 -0.357538201019838 loperamide -0.436101832077648 -0.343846608185884 0.191650659549252 -0.246064624281519 -0.281512344878373 -0.0665576731348136 -0.534325643244197 -0.415713728407951 -0.350815141249715 -0.447419433231803 -0.503296805590396 -0.54545534657525 -0.307011837538738 -0.462442495855232 -0.599665116579789 -0.372423710169894 -0.410222332248362 -0.318283955910923 -0.123241879003253 -0.476256990260445 -0.335919120038226 josamycin 0.27118988115319 0.357865211761198 -0.101961241666906 0.226852138385385 0.278122637033924 0.0585274540328755 0.183532251664131 0.224428231603695 0.330060709176353 0.390029091375333 0.250885217662553 0.431421151582289 0.391418446139234 0.37125290547791 0.382490086984157 0.247200313112859 0.128852940699453 0.312962004934207 0.215463854280865 0.0913260157374201 0.127106108234327 baclofen -0.122031829748559 0.0387158321303242 0.172943283531927 0.169326887772397 -0.14096849649025 0.0299405058695819 -0.0343108295072505 0.0279695253065507 -0.130233888640168 0.0154311777113605 -0.103361175987586 -0.0949308221288895 -0.0817786876456394 -0.193238463902785 -0.1155891403419 0.018823720632604 0.0913580024378974 0.00120088483346401 -0.0208472853869554 0.150672213592016 0.00830084977449107 lynestrenol 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0.598932055863834 -0.055453989242953 0.113895065505962 guanabenz -0.0874318186149168 0.576949049476699 -0.193752376356748 0.555400969328862 0.286863110286219 -0.0944011433140044 0.126115485368145 0.468327691486759 0.40999893976138 0.319313448272341 0.46497682374294 0.414686018449052 0.440759196808945 0.540899609348706 0.545106516201274 0.503794017765794 0.472507215598516 0.478033706476452 0.690582735514867 0.166697559238738 0.094660605529031 lisuride 0.224252819770437 0.650520905180023 0.0485861123286892 0.499216195495717 0.544839974848739 0.242292430889397 0.265246967825719 0.615855802181123 0.192155785978137 0.48759563348886 0.215995743524292 0.572205903627705 0.553624472366351 0.643414638299554 0.550823768586475 0.641007370875865 0.492798479805956 0.406152394319844 0.702148553150921 0.241261377157741 0.348150192394686 glibenclamide -0.082909110503836 -0.535143866764972 0.220165941246193 -0.523882160791299 -0.467036277293988 -0.115460862405747 -0.145766723146251 -0.484664504613348 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-0.21770583742214 -0.422446574305209 oxybutynin -0.0424594333967583 -0.404248326497176 -0.163389742324196 -0.489535582546758 -0.421309519508849 -0.151125334385053 -0.00222330696680109 -0.429575749410556 -0.32655357007237 -0.469574247653949 -0.213737309312599 -0.313553821846704 -0.43052769937333 -0.439605995653032 -0.584959425807217 -0.400452603949297 -0.385028691644327 -0.512243532878657 -0.503800310344271 -0.295614635802626 -0.485629524328144 benzydamine -0.126104011575029 -0.0926673387406926 -0.00409699816423476 -0.323001892994421 -0.314379855456167 -0.262723617483042 -0.323379653084402 -0.24268651916408 -0.201255577756588 -0.525512845703131 -0.291918564302169 -0.239861884813888 -0.264103127713108 -0.252774593312131 -0.151822949522191 -0.0134695161546815 0.0191576429335287 -0.2399100246274 -0.0213265082357199 0.0080301872024698 -0.0589794349127745 oxytetracycline -0.330219741852352 -0.573459946667779 -0.202979508952159 -0.512236888267607 -0.546608078222808 0 -0.129130549779393 -0.581193771337771 -0.551139261941728 -0.395956876037621 -0.253029092315828 -0.531346905521092 -0.591417575938491 -0.643425208278386 -0.676072598931564 -0.60635123842286 -0.334258753626575 -0.566956392716271 -0.48058027908875 -0.187730547251385 -0.676422315344513 guanethidine 0 -0.386952513756294 0.176624242633718 -0.30861328867709 -0.466891248989202 0 -0.272949306363691 -0.51435174601125 -0.324218924336557 -0.320436994554388 -0.345349168726439 -0.448638903099524 -0.533458331571397 -0.420518341617502 -0.550160191878856 -0.558179450772155 -0.288056155239172 -0.53551690725389 -0.217766952863274 -0.29126293260785 -0.00204139278691133 clonidine -0.0920813594170322 -0.093223237289172 0 -0.186940431949168 -0.144415748060478 0 -0.0166391903300687 -0.280689281101083 -0.0914971477110468 -0.382909637547739 -0.166548287038916 -0.196770757268001 -0.18713060909144 -0.294503458148052 -0.129629394791204 -0.279062801196158 -0.173690285201964 -0.212182593355348 -0.298429121525336 -0.178185708139648 -0.325755801053462 antazoline -0.322685642915097 -0.249194407832694 -0.12962677466714 -0.109645402905096 -0.338735730425597 -0.465651587700579 -0.0659571885478552 -0.309995227542232 -0.171795711178998 -0.459048808853398 0.00657302913190915 -0.1024717806164 -0.351746158222015 -0.370036185650166 -0.371069506754416 -0.358663679586402 -0.140512940097549 -0.392100151118621 -0.0952178360188792 -0.321743226292133 -0.110050985310559 vinpocetine -0.0192395862823444 -0.374640543392981 0.133131954598411 -0.466650704298076 -0.476445672555631 -0.177698035670592 0 -0.427601456989112 -0.292896767559594 -0.294555764711366 -0.146608885460589 -0.405983418058872 -0.379374648039728 -0.371474011091249 -0.496811265170638 -0.390630578250939 -0.281051443450639 -0.361631736481359 -0.377751461646223 -0.183625801956075 -0.161807680639416 cinnarizine 0 -0.0414744782584047 0.0795305011731551 0.0472695888329955 -0.0425021672263674 0.183412720773874 0.153355319285065 -0.115970074209929 -0.00209581900943812 -0.387722630352905 -0.0061186448048428 0.00757249122964064 0.0992979553140248 -0.0504389487309929 -0.16710266028493 -0.0609467786937134 0.00544975275207621 -0.0708520310167739 -0.205222308937954 0.09266248047543 0.145951357346451 spiperone -0.637660711237486 -0.481981351376251 0.0815123950885352 -0.421990483648412 -0.459551332323572 -0.215284310382343 -0.23600789058888 -0.51092825038143 -0.593544282754449 -0.595662882486568 -0.610335389158853 -0.539475684026917 -0.624180296411818 -0.681660728697004 -0.739682442639133 -0.538068288536189 -0.581086975917571 -0.643509634916844 0 -0.546579697753751 -0.363280996740858 fipexide -0.486378295828697 -0.505333614822541 -0.158834008326402 -0.21504184347803 -0.547716556017662 -0.158411637179856 -0.340816329114037 -0.544472000942201 -0.325686683261395 -0.368388745976295 -0.395768587716666 -0.338209137216423 -0.570218667042528 -0.421094470684428 -0.577420800367934 -0.434305953344511 -0.31916440116576 -0.408343208057603 -0.61108772335901 -0.406436319012482 -0.210625722069827 pimozide -0.467980156602158 -0.518314149684607 -0.108573469772096 -0.341737803327953 -0.489533311459877 0.0186430632805535 -0.598116348934479 -0.562635489490731 -0.61293282311317 -0.305377366943407 -0.566333961023865 -0.596987961595815 -0.646769585155411 -0.627670181117765 -0.662293568969303 -0.575837370821868 -0.389642347257795 -0.553243669280457 -0.432780629510781 -0.356899233928454 -0.706776730446127 mepacrine -0.30401317270068 -0.539682216824348 -0.236403628622414 -0.46826844999799 -0.398684543895019 -0.651067573714141 0.0181250075349892 -0.562385828913581 -0.285370046671499 -0.0711020034689337 -0.0845315568380021 -0.328913323476408 -0.601820025576488 -0.386980333069876 -0.384273801327042 -0.338050047763993 -0.481504629517544 -0.604555351260386 -0.334356675510052 -0.466917673821302 -0.333364122757458 bupropion -0.261407056057757 -0.307170510797924 0.247378613727299 -0.366027237991578 -0.497508312035049 -0.122496653354813 -0.217534635197142 -0.568328985582808 -0.266994132704959 -0.442859744782297 -0.3989940498689 -0.527258889772252 -0.457817714078156 -0.485858052465653 -0.631218386979367 -0.341523760333318 -0.239271421768578 -0.339956044073878 -0.458396620287525 -0.134723936025557 -0.597118714988166 etacrynic acid -0.424082368230084 -0.620453897354668 0 -0.459468511955909 -0.41005333061449 -0.152110685363479 -0.197697160148997 -0.416006872691571 -0.64824559836194 -0.584712519534924 -0.571171724350226 -0.542689012902418 -0.688712365887742 -0.717852540104861 -0.498797786612804 -0.470481573377562 -0.567226826016577 -0.514317184360397 -0.632225037023687 -0.339500253886313 -0.15838332775653 clomipramine -0.617992565549099 -0.625167403436908 0.138199522535106 -0.546265996859075 -0.627032784203356 -0.371646274253404 -0.599617176822692 -0.680715272747239 -0.624276665953713 -0.674857394631401 -0.650876610102673 -0.675133432881119 -0.74883529771958 -0.706922849755151 -0.749004029872136 -0.655297562201915 -0.581599204682332 -0.703255371433102 -0.663647268533077 -0.548706505445505 -0.568368333395012 methylprednisolone 0 -0.546561590393194 0.0483756213293097 -0.518768940249188 -0.542072195653159 -0.105189361382332 -0.359822767864903 -0.412726945364934 -0.469638563633345 -0.520035215003095 -0.325339193365325 -0.492013661404652 -0.562832329404911 -0.584259503527709 -0.558696475969806 -0.532016750551542 -0.400180951365118 -0.515853129356721 -0.614700603782709 -0.311681574217053 -0.59683649890982 mepyramine -0.1519658722395 -0.383595651516035 0.298505146242896 -0.350856380950678 -0.350513698370279 -0.140340164913417 0.048831213080573 -0.395581158135367 -0.267564427642442 -0.288940999628989 -0.178504842322749 -0.267609841792632 -0.331165768804418 -0.39082267085738 -0.394098402089425 -0.3930918813452 -0.265096171242781 -0.350793920552784 -0.40795802953346 -0.30903149135641 -0.264864900632969 mifepristone -0.276213245745808 -0.181851859892454 -0.0318332434661474 -0.40724381682188 -0.0461775911639221 0.22835946829085 -0.011715136485461 -0.107530081803198 -0.261978140219191 -0.317666250173655 -0.102717408501417 -0.0237893563871261 -0.0390450558551063 -0.184550603747629 -0.216023763032368 -0.205092307246241 -0.123349678905119 -0.171060011013648 -0.250750588430024 -0.290812445713169 0.0682017430613291 amodiaquine -0.153945355087791 -0.41532331071097 -0.263417622073427 -0.303846215836952 -0.357227138639998 -0.401704083330763 -0.268561982838446 -0.428736519425658 -0.464442962229073 -0.422129146854402 -0.322145971833086 -0.162899698397363 -0.547140659098808 -0.567867272220691 -0.436506136307378 -0.512748430697853 -0.458594787577876 -0.441665076061768 -0.398262308261488 -0.340321842192459 -0.29905170961925 alprenolol -0.0102172387672676 -0.0770589597155237 -0.273974620599121 -0.0473481025849106 -0.186776146324545 0.156563298638814 -0.221964045979129 -0.190051271642866 -0.0568815890711548 -0.0967214372098732 -0.120262894050638 -0.158830580292184 0.0284364939174809 -0.0768228116830997 0.0525306067703186 -0.186907008081328 -0.290706273772329 0.0193257970527744 0.213606379607768 -0.163326655037195 -0.227611123879914 praziquantel -0.220609934664512 -0.0959210457985279 -0.0329278910254829 -0.217221558104764 -0.0872113826966597 -0.123720342703563 0.127808183683551 -0.0218745199050245 -0.0619038187012333 -0.0818910315340187 0.212433552422946 0.0311671716085202 -0.249300060571355 0.142827962987124 -0.232052149006941 -0.0105604161470035 -0.109087394004872 -0.00993520550998188 0.121979472123698 -0.00542034781021188 0.146982240727581 fendiline -0.186485107553206 0.0291716724073163 -0.0635017709907768 0.0243738216053015 0.178225968707863 -0.328595608575438 -0.339006292963464 0.0305888175840917 -0.0741102262358134 -0.0225151574028249 -0.487776554703236 -0.205993459227 -0.361606779756957 -0.16527729854025 -0.200067901815504 -0.0374927046142406 -0.200498671411612 -0.189507920665379 -0.0201846794856594 -0.163044365573792 -0.510468158043642 sulfinpyrazone -0.00225995594719976 -0.464210806837081 -0.311801446796175 -0.437540520163868 -0.397826644173866 0 -0.212956842265068 -0.407138032953549 -0.373092523083151 -0.285542026232276 -0.324386510264856 -0.508979773421932 -0.523718887120673 -0.43973322350304 -0.592069174340028 -0.520778019585878 -0.382339874060018 -0.403139243254212 -0.571915270185472 -0.0706917874835127 -0.132199953267631 diperodon 0.162548469500963 0.0708835298027342 -0.148993680267769 -0.276638251589259 0.0502505170134537 0 0.0175638560514541 0.0655302744550355 -0.319134868723631 -0.0489389889780731 -0.0166045097432081 0.126125474402298 0.109017799757955 0.0745892098199693 0.103703705036396 -0.0954511536291786 -0.013275702194563 -0.283509196485227 -0.0780445752520241 -0.144863419079286 -0.172387131211407 mebeverine -0.0880266551366793 0.0614305469434837 -0.332641550062268 0.00977749179008224 0.111307818277783 0.217264910203197 -0.177645001006295 0.0238970475841095 0.229043511022977 0.178081103311417 -0.0997565250808033 0.0514098096410059 0.135645132141481 0.136878522228245 -0.0141614892746791 0.137637022973696 0.0108637797683802 0.116747405527976 0.0290732616872773 -0.158181702909809 -0.260048790298654 streptomycin 0.237297831132005 0.398710048640621 -0.40085495019022 0.257615692323248 0.383894259907153 0.242773459626282 0.0522813430621209 0.515057547367242 0.115514379403063 0.206030350683792 0.0261592449370622 0.351971813422498 0.382493497421206 0.394510547731613 0.375420333036008 0.379135339496747 0.343673011890542 0.345112234485758 0.225696930141855 0.466465770816404 0.181496169194513 tremorine 0.0149145744942258 -0.318692469857803 -0.1453361085622 -0.305012560949689 -0.23737354028201 0.0613809812250379 -0.0762102315916999 -0.208199974063517 -0.234765007435746 -0.238769628651801 -0.272957154099711 -0.189977878145751 -0.452152084351436 -0.452372524856639 -0.469851525264955 -0.300247795755973 -0.296860372677428 -0.319055764187741 -0.582790856422626 -0.181892169502043 -0.600972100996438 furosemide 0.235140251292574 0.243632725851208 0.220421635015572 -0.0123230462239559 0.223789034279859 -0.00165095163210549 0.242745228067654 0.241160292179563 0.25365654205664 0.326132947669107 0.231643950182764 0.310154596869981 0.311260121345328 0.288729405857097 0.273742871323647 0.270495559167832 0.122139415666444 0.129203186321486 0.115435975271595 0.121464297164505 0.129344049156459 chlortalidone 0.142882017812695 0.386898573706502 -0.270981406379677 0.375781888014791 0.367826093831461 0.331212354875188 0.336280136051421 0.393953724925379 0.317148286901223 0.358532694376296 0.0421228657653948 0.327640556350075 0.35110177396447 0.327576500470148 0.322369807846503 0.363790411719408 -0.0281717721343872 0.341168523762562 0.371793314600095 0.167119261422866 -0.167196308909648 bambuterol 0.104425181099668 0.374276983594781 -0.275649890465565 0.320345165585864 0.217534742812986 0.0279244671227893 0.0423540198439249 0.169354781221502 0.270805496832023 0.215142220773391 -0.119058828885168 0.290654622331618 0.317444406782468 0.344234259116747 0.330265282546135 0.347957097359938 0.086655597717869 0.340669650700302 0.165008368152156 0.335316274149367 0.285510180943069 ketotifen 0 0.421013006172534 -0.285653526756375 0.441559509777233 0.402988912073004 0.158217941726848 0.129920964204602 0.394161820979999 0.309794153649158 0.375383946366585 0.109245711061622 0.443914441190018 0.435994241756295 0.453335933184176 0.403710860701227 0.446529252195364 0.20611847244998 0.404238406545066 0.415857881914666 0.349331628782229 0.164257898913371 terbutaline -0.0719891389289688 -0.103247521869917 -0.37360485533423 -0.270240421999409 -0.076836246135154 0.11956189305679 -0.129326523944209 -0.200950457336717 -0.085354150650201 -0.191262949356067 -0.17243606720997 -0.133753427344919 -0.137526395062211 -0.136414048106149 -0.118658060776823 -0.154543131466969 -0.110882504150545 -0.21757239702963 -0.363288915646693 -0.228338608763189 -0.391697543469049 alfuzosin -0.108856964376175 -0.487491287320926 -0.14162323474318 -0.47312584182295 -0.463079220728886 -0.0703521530656982 0 -0.384027457626427 -0.293451691009657 -0.396661610332948 -0.221088382680027 -0.348316084823677 -0.35450808359205 -0.497878160088206 -0.486917852636062 -0.330703036245858 -0.480651605214493 -0.476308274114659 -0.383426341544339 -0.339803727802569 -0.347722955317373 practolol -0.152529274113127 -0.413193171052012 -0.14968742232452 -0.273174256769615 -0.449530927801804 -0.147158249565714 -0.177600546937035 -0.392495388098964 -0.260040505682613 -0.534091879060875 -0.330024523824207 -0.348308681550847 -0.558175398995893 -0.454032837892969 -0.444048463307811 -0.451019601915538 -0.273604040892806 -0.419802027988219 -0.478950214045149 -0.353371879446063 -0.245617165945292 methapyrilene -0.0367347451018655 -0.488022020758964 0.168567167736068 -0.355687521076225 -0.455649916150822 -0.243847516111436 -0.141464339532137 -0.543303123962947 -0.571832809519327 -0.556075068052032 -0.254620381631632 -0.478114097993155 -0.500371803737447 -0.524477009917777 -0.494444560970861 -0.476728125306771 -0.430094809469629 -0.50544885966008 -0.240702466071981 -0.298689758422736 -0.403810788741368 dobutamine -0.357619492073101 -0.185231941550853 -0.0963814170884797 -0.0701432361383179 -0.399709980686234 -0.303061207773896 -0.332617518700405 -0.0861210288512591 -0.185674455768236 -0.104262835307169 -0.268994736448177 -0.325713878234333 -0.358615304593527 0.000893148242230496 -0.192252202181001 -0.333128769906116 -0.132880510528467 -0.105917543429036 0.110634982658914 -0.289499495687431 -0.372664077207141 betamethasone 0 0.0179068875214822 -0.310158853394952 -0.163604545228851 0.0146482208946181 -0.620773583747655 -0.211029758116696 0.0241938540395364 -0.0284315518363386 -0.0571847468262687 0.0206206272666427 0.0846270623351805 0.0770393547552075 0.0940041727389757 0.0594190999385545 0.0844392906108905 -0.100356612232923 -0.111879555422645 -0.110588062910287 -0.237237229317164 -0.0326472213883705 debrisoquine -0.0609640769908029 0.191491192571977 0.128391212612902 0.321567409977452 0.20261805266173 0.0021021847506832 -0.189359820811708 0.230288103910054 0.132693179676437 0.038205077570482 0.249687008998071 0.0702482278570196 0.0599281781846678 0.0831907173938944 0.105747284748121 0.11106711850992 -0.18433113295073 0.179522560872737 0.137140943684753 0 0.307898400511438 betaxolol 0.0926620335942677 -0.510091540954439 -0.105414315268999 -0.471574002969238 -0.447993690271367 -0.282940333806628 -0.138814394676146 -0.402972994593682 -0.57179949885633 -0.574195831058967 -0.334146553677454 -0.432172179248149 -0.514333730701441 -0.523848659655531 -0.505795000767822 -0.475156764448558 -0.288151624906841 -0.469058281215812 -0.656753119511477 -0.36475924296287 -0.452318694034013 ketanserin -0.314370024793324 -0.614173093108704 0.137517322345821 -0.455565978132576 -0.532138559251684 -0.183747570506092 -0.152835692545837 -0.45023760068785 -0.538280299407273 -0.572383309390563 -0.453323420784871 -0.53551436566004 -0.665793599797402 -0.665838550903639 -0.641246586950062 -0.60504918738283 -0.312204842074701 -0.569454671452719 -0.514454054452725 -0.300662127926288 -0.649634157183628 zidovudine 0.0441928128241135 -0.0254220258096616 -0.288977503205717 -0.114810732194611 -0.00156748119222253 0 -0.0157220331014407 -0.0126273959524573 -0.263468379790458 -0.314528568054243 -0.137799389021322 -0.0275480035504262 -0.101737669973016 -0.0867492329670811 -0.197129438127873 0.0387173195861398 0.0568589909162852 -0.189863554113868 -0.0652877988227144 -0.0532912527850157 -0.03443769236501 desipramine -0.114629450936375 -0.225982156724059 0.176938711915046 -0.106589502193527 0.064633114376673 -0.221928806040688 -0.395496165418126 -0.157025727222203 -0.0638251914214043 -0.149229292168336 -0.236582574144179 -0.273469300432054 -0.303357013112316 -0.242343359970568 -0.454036343039416 -0.217928353609917 -0.171666427525776 -0.284668737481023 -0.0490719529764887 -0.203130995177554 -0.00233359959970113 enoxacin -0.109372165993463 -0.327378913581318 0.237888584352114 -0.28869078992361 -0.191725669279299 0 -0.0810351660570066 -0.352332040080452 -0.182722880518322 -0.240702690647591 -0.0978556533801216 -0.224892185959518 -0.264541493986028 -0.297709456598115 -0.281198304492215 -0.263193125054236 -0.142998851808119 -0.171553734157629 -0.301670543868448 -0.221169595127661 -0.260916927716137 methotrexate -0.261039189775739 -0.213444608187491 -0.00551435149578816 -0.245772947258386 -0.288145042501739 0.101440413370464 -0.255684989010741 -0.316474142168863 -0.238949093512163 -0.320493596698293 -0.396729997131791 -0.281531262411455 -0.207659878588712 -0.372898728097263 -0.429440015933057 -0.223484142847142 0.0886002609344001 -0.226161085483849 -0.172938501375902 -0.256761592372555 -0.111058264746 nicardipine -0.110704785020885 -0.126156133688262 -0.132026036238219 -0.0755466853555338 -0.183552563767201 -0.237061882121578 -0.151764251787421 -0.181182569932699 -0.00303431774156451 -0.247823436668805 -0.238714283257785 -0.234418982979687 -0.249710529129947 -0.251380395964474 -0.2860276681465 -0.0848092521609111 -0.0536471200420026 -0.221747045832327 0.0927544209938809 0.0241382236160157 -0.0686278850606443 hemicholinium 0.0959513610232201 -0.0580937586791657 -0.134590552158793 -0.0224779524611123 -0.0515799910728928 0.0030397049518778 -0.279244357448326 0.0966284741239125 -0.00715428648905887 -0.0155930070106919 -0.0924276772065617 -0.0411703531706874 -0.168579549649304 -0.0323522025569929 -0.164973622927762 -0.081642489487411 -0.344265986614591 -0.343682974762709 -0.0323685046927258 -0.0467425475671571 -0.115775984541378 phenylpropanolamine -0.108675593557513 -0.129869561255502 -0.113456418404001 -0.114101703732721 -0.27462175275458 -0.142017674142751 -0.0230713328018209 -0.192115579831776 -0.129788085681522 -0.200122725071927 -0.0848437692899934 -0.187840599700474 -0.084559963243342 -0.102780749216251 -0.17466364789757 -0.0650400610646915 -0.0563276779130741 -0.103243418186312 -0.0807466885253274 -0.176126604971205 -0.0524553004301065 sulfafurazole -0.475410168137302 -0.425161761991151 0.197154447247931 -0.210788534106583 -0.524299183419209 -0.228343993848427 -0.452956265138521 -0.385327671643161 -0.407670147388851 -0.437325974278396 -0.240229417176325 -0.44306284818345 -0.426248366839448 -0.445849317673066 -0.436048023968023 -0.529390026026751 -0.395556033305745 -0.425909438868376 -0.372622527370122 -0.283414517470112 -0.522252101238815 clorgiline -0.484757164758905 -0.43292318852576 0.122682596191175 -0.387935174975853 -0.414952063806259 -0.332935652834637 -0.437516023422578 -0.447514564867762 -0.276208527555445 -0.344869237110878 -0.25552026067406 -0.304680687382723 -0.404045647874547 -0.457804559625098 -0.410418758920599 -0.394136439718461 -0.261678472340507 -0.400471887634036 -0.38690011463693 -0.408834048793948 -0.476618551136818 clopamide 0.072155499813348 0.10476190741507 -0.273868744235941 0.276578618886055 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-0.513607610082412 -0.664966332395563 -0.586708715640518 -0.659183853765428 -0.69763274885296 -0.43231515017568 -0.431262887977004 kanamycin -0.285097039850495 -0.463210685112368 0.00983792688032016 -0.313947033089949 -0.295305276662371 -0.246107002606607 0 -0.320759473966078 -0.24467558289098 -0.285655141134714 -0.166268899375903 -0.273271559037406 -0.327805141523784 -0.474352701955577 -0.350402446790542 -0.312711149630077 -0.228381297716802 -0.344013886842833 -0.214071309328369 -0.0573408486051043 -0.336641715375511 ascorbic acid 0.0343365544090857 -0.00957894980422941 -0.142123467879592 0.0388470134439288 0.124080911567704 -0.270459334178269 -0.362496297662271 -0.0011854801156284 -0.153096568585734 0.00431330917908211 -0.197891575812462 -0.308249279631861 -0.261812547530048 -0.0112609090362549 -0.139801004409858 -0.0732874515084549 -0.0307772031967652 0.0231617177987706 0.132826686346858 0 0.0189621086873865 zaprinast 0.0909833704720746 0.228791703983167 -0.336489910646119 0.14213835035767 0.161671968922532 -0.30946738861692 0.0410898027940918 0.208365772795571 0.346437953562306 0.298658859361841 0.29677673085903 0.34611908453633 0.295820700032776 0.298996239026227 0.289855147264471 0.239300193091403 0.133927202875468 0.259062634868932 0.242714949608668 0.0944182873913407 0.0941536908412227 clenbuterol -0.329371036658914 -0.107419358645576 0.16769191784267 -0.0957335697234728 -0.165097098688227 -0.247395923078012 -0.255846802335413 -0.0824508202804287 -0.122978725033161 0.0114477664399537 -0.177606424971095 -0.102188393113046 -0.155799297497587 -0.108220297520952 -0.0907742923266101 -0.181392744211336 -0.143881708099191 -0.168915112954666 0.0220087894704257 -0.187405486891237 -0.169828412041895 hycanthone -0.27071609207115 -0.0852997132681193 -0.0237958657701764 -0.0121866104228328 -0.312026008204151 -0.596042011900983 -0.277662492595681 -0.225493720149183 -0.110859735882386 0.046194953769591 0.0717698723266788 -0.0139705967056512 -0.0669141498512493 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-0.343806342380733 -0.261886881742958 0.0778041501170845 0.15404461792271 0.283507448377368 -0.0432857825243582 -0.15488284711242 -0.14336632905951 -0.0512218088454068 0.0463653079088044 -0.079608348620488 0.0284020169724292 0.0289189563938633 -0.163589853837003 -0.17678968085221 -0.0657910163644026 -0.341863591966073 -0.0140690646997798 -0.0409049079901512 methyldopa 0 -0.208435341668792 -0.0372460331614615 -0.117893274837001 -0.145189509168793 -0.130455689241664 -0.0215543835950335 -0.165801805788756 -0.219785801776387 -0.163232175008566 -0.21813036487069 -0.17706138990653 -0.205541599997621 -0.220829340831873 -0.150222432744436 -0.229985378501971 -0.246452633680322 -0.161331655332128 -0.14906599632304 -0.123050033134379 -0.327204756056306 chlormezanone 0.0850859680470067 0.097842088568772 0.218499587433616 0.18582156746801 0.199745152654287 0.0542082482488592 0.132872948517153 0.0907974313750821 -0.0925258828262289 0.0686169820870765 -0.197400432646869 -0.0401565363329886 0.0689196201081034 0.0614092326910989 0.057944716556661 0.102210648556027 0.0607468670976699 0.187984885692242 0.0544631890336464 -0.0848808423324162 -0.143928297773365 maprotiline -0.262275625274178 0.330020859064487 0.193439402008848 0.322443516670028 0.285069429027693 0.1554977906458 -0.167315611478895 0.310971873708461 0.297210715862265 0.28721963679218 -0.016691510692914 0.111027421990669 0.149746108092342 0.331862778070879 0.264736440392268 0.19367882433764 0.161843949472892 0.154456974604148 0.387192072344868 -0.0989067161258438 0.118778472466979 adenosine phosphate -0.139469335148755 0.0139713059423777 -0.154580413415176 -0.0541987195733941 -0.068488212998706 0.0125236067300681 -0.14203161138565 0.121978873946875 0.0862491016028422 0.136354157292705 0.0748758755428669 0.12108794518305 0.00273397474969973 0.133889239683608 0.125900259569819 -0.0354540417390731 -0.301089124088457 0.0224330287239102 0.107243102581441 -0.190124507457155 -0.0446328413764608 ambroxol 0.421896730801035 0.388335054673855 -0.48154537485887 0.275779179599596 0.488372921273229 0.250963484448148 0.149215090382654 0.523957053904056 0.384547933453289 0.412920446179132 0.125197457435129 0.290246708161512 0.465493693763703 0.301787012265073 0.31215014163429 0.295023997533785 0.367031560861528 0.384280619657406 0.252805160285057 0.297864759215295 0.276196096983002 clofazimine -0.118232179441478 0.336448712835307 -0.0906808029017163 0.304295604349132 0.22295558305124 0.217705874449352 -0.132433078152743 0.241674378676629 0.185391444411518 0.230618420002203 -0.0737558444164712 0.26741968924303 0.377819568280692 0.31823701699106 0.242497463034931 0.313970213482333 -0.14152529186276 0.238064926183002 0.383051103524946 -0.105232865367686 0.0956927076247626 vanoxerine -0.103611969588125 0.178758303659753 -0.404546912617243 0.153938146088066 0.215611918537161 0.0905035818164521 -0.234599011147222 0.281434810646695 0.07549332063824 0.019842084760603 -0.0350264082694182 0.0839126414816144 0.106108910527798 0.0112500338094761 0.0029484831829972 0.152203745202376 -0.00272593467794535 0.229319934494999 0.283926931865091 0.0966710794641233 -0.195883238733496 etoposide -0.562487790629167 -0.171364390853411 0.241740270126432 0.0172883428071288 -0.151805111811003 0.0822103419068708 -0.508120002895729 -0.150851091583348 -0.252345021565729 -0.291677713863925 -0.519535778102865 -0.315990002715495 -0.303610627756888 -0.186198815312812 -0.162879329081104 -0.167014857893429 -0.189634549173276 -0.179003352018066 -0.159590582450726 0 -0.425370372221544 cefoperazone -0.198827358523611 0.284991273855004 -0.184398736115099 0.282609511235417 0.234888251712103 0.211976887827106 -0.183890453094086 0.27591380663265 0.182698485889919 0.224974298977294 0.133274701121254 0.257374626062804 0.218606158067473 0.250202039772012 0.262188962170114 0.263504083802978 0.226626556374595 0.212973955064831 0.262511503273581 -0.190485696134651 -0.00958606845261293 8-azaguanine -0.440426075492986 -0.82114474693594 0.416004405800334 -0.705276463031516 -0.758356615794941 -0.565634382539612 -0.14975352161032 -0.787447856895132 -0.571561188647333 -0.752092973981624 -0.627535775869578 -0.751634546948544 -0.821550702338528 -0.897463290248568 -0.879440900738204 -0.802690453278615 -0.547032897358675 -0.819047429281412 -0.840012068103049 -0.50010348110803 -0.708105769012622 meticrane -0.258009356798208 -0.705248447872727 -0.0919922158082238 -0.607655195436093 -0.660267971267465 -0.220682060469414 -0.0896918451001564 -0.670101552801399 -0.63670160071946 -0.724717440048475 -0.398413464420381 -0.647286353500063 -0.709240072160483 -0.752738170397033 -0.746454711284285 -0.718842910099738 -0.575935747466285 -0.693711582726947 -0.754973291148578 -0.201168307224572 -0.633772418202007 sulfaphenazole 0.129020614822529 -0.0856057530297014 0 0.0185076894052506 -0.0132653272961208 0.156342159208985 0.16739639789249 -0.0333890977426445 -0.0517468970578032 -0.237936722374413 -0.0498858747091181 -0.0794315907950844 -0.086399516749977 -0.133292725281821 -0.128551652207859 -0.100530200578523 -0.159272887623261 -0.0824998856484664 -0.122333320524736 -0.0187488658546066 -0.199646574747328 procaine -0.243298677733198 -0.630228664985026 -0.0910200226915837 -0.481353406730723 -0.617806415296846 -0.133972353294921 -0.224918543159566 -0.633355819548738 -0.468554197065172 -0.64935815190555 -0.400805472947893 -0.636961963976946 -0.651803552252131 -0.735249202944238 -0.673413673003858 -0.673825431863053 -0.580227331192079 -0.622104755752709 -0.600293202969924 -0.416204611428492 -0.433391673317399 metrifonate 0.132495515077182 -0.395311151188565 0.128609159762456 -0.33246990692743 -0.270991988113512 0.0941310289915944 0.0203990815098502 -0.351937900214906 -0.39366308256881 -0.342533728061656 -0.181939434669674 -0.217104223684536 -0.39144645380336 -0.411862078787445 -0.4053006594508 -0.386989941120434 -0.361181440988515 -0.241166475289675 -0.291735111923667 -0.300223522666331 -0.212661247767693 morantel 0 -0.704313677800158 0.000952810079483912 -0.626600999074528 -0.624265065012183 0.0867025054192426 -0.300843451731903 -0.65073727660489 -0.663655172363351 -0.695443053068641 -0.41167413665291 -0.603600987249694 -0.689195492425936 -0.756376348799158 -0.746376234788334 -0.719978563982311 -0.428132666120214 -0.678590483638039 -0.80662865348442 -0.277567881764069 -0.631142477764259 todralazine 0.2155601865072 -0.314767386056836 0.197051787822675 -0.287253450255387 -0.370180306970132 0.0176954727547891 0.0633332718624867 -0.300597735222218 -0.40232143556837 -0.22213934851297 -0.193850412561843 -0.167919237231875 -0.202752719804075 -0.345248331780427 -0.42339624960721 -0.317654133254544 -0.27618693843376 -0.494584647706696 -0.454692290050881 -0.207386725979825 -0.376782235838711 allantoin 0.110318290252525 -0.542013324489798 -0.076728571547265 -0.442418381373564 -0.139129504063825 0.133504510483655 -0.185850173687417 -0.335610488393052 -0.379153029373882 -0.17296402333487 -0.15664130724594 -0.109429443573253 -0.376465151182429 -0.485051652907942 -0.578893929630806 -0.4829451993277 -0.304819233879349 -0.340596703399264 -0.475982048573368 -0.291559471635394 -0.142750333720915 benzonatate -0.0766387689144131 -0.336994999379856 -0.0019195541917285 -0.272771635068801 -0.319395819567551 -0.197528926804668 -0.0828134256968792 -0.339611330932243 -0.366315965012937 -0.39174086804181 -0.324075515107346 -0.205676014814833 -0.365575553583364 -0.375968767625123 -0.366889135594707 -0.337142320387222 -0.272079004199397 -0.490582041610334 -0.326528115994316 -0.174929454810449 -0.370500783487082 dexpanthenol -0.00597767901900657 -0.241399240226939 0.251790047344403 -0.307641372697734 -0.238572900281997 -0.159188954147957 -0.142720535915558 -0.294703562714625 -0.280499563816303 -0.108276664962736 -0.114299012011614 -0.174818431164613 -0.0738135973172771 -0.337725512591348 -0.30039879960162 -0.213888073703027 -0.282243942808545 -0.341495480959128 -0.369496975258659 -0.0354379584729336 -0.164539049328961 epirizole -0.0753619757815769 -0.343243164304911 0.0289427702730008 -0.301205800663641 -0.367498774154769 0.0942315590629272 -0.0819840379492157 -0.363215450744381 -0.356834518050786 -0.319356261156134 -0.213232966871055 -0.283469300622528 -0.351799305322184 -0.400436774605867 -0.357428415142839 -0.36374897465733 -0.191626174666252 -0.351804476865697 -0.371908180527337 -0.135045947054522 -0.128921833871571 moxisylyte 0.115692809056155 -0.336667290725092 -0.125072492132261 -0.222850684312027 -0.135772851436343 -0.198907489716738 0.144511372944864 -0.381403811516513 -0.12378707902014 -0.308761750605292 -0.126697850883185 -0.357430718435282 -0.313181249123265 -0.363681187960524 -0.437670995556618 -0.334005710396298 -0.288398320367294 -0.471793615480424 -0.230236795481791 -0.335894750233295 -0.118124601353926 homatropine -0.0925833049829722 0.243015778072931 0.197405825349507 0.285743845905766 0.180853082219116 -0.119099669276668 0.0287258056375723 0.176335214259861 0.260540448451324 0.239348906330493 0.174590844627661 0.213031726875669 0.226099618101275 0.238609453648752 0.213514319631231 0.250594871751858 0.405321526842024 0.239275493580723 0.263838434344051 -0.188902589731399 0.135216135800867 imipramine -0.286005949197885 -0.474833139846462 0.130472090137114 -0.472863422144561 -0.394264827308673 0.10414226771316 -0.441063881946945 -0.474450268311545 -0.496439463146631 -0.643663137345954 -0.492235823099776 -0.602232024349332 -0.630079100457044 -0.622292726469131 -0.513995590621545 -0.565239483479267 -0.547664838975245 -0.654949289322395 -0.391750935072354 -0.371195161283905 -0.260342452154279 acetazolamide 0 -0.365376973020821 0.162681007414355 -0.319457176473466 -0.397894270401871 0 -0.270237193212061 -0.363937013139002 -0.311232695311414 -0.315225895324822 -0.17433640130177 -0.274827986022988 -0.325066163472373 -0.352826270873083 -0.344093695977524 -0.349767390908668 -0.277918961927833 -0.346206908332039 -0.396037988859487 -0.149714670347981 -0.434698969247449 hydroflumethiazide -0.115368900770483 -0.165618632399954 0.265498546517457 -0.1525994585952 -0.153277350498687 0.0909962627432418 -0.0801984363568305 -0.153654108468595 -0.0905345091410648 -0.289756830665949 -0.230085188733613 -0.1540796914044 -0.172956638143165 -0.262681298222204 -0.135257089180713 -0.17634168347451 -0.293163279264737 -0.181804467293003 -0.191787695864631 -0.249272121741815 -0.165718252578077 sulfadiazine 0.0960088210961673 -0.256072464344399 0.0325286965845757 -0.333254294097603 -0.0426780726175937 -0.287320397708728 0.0470112827241489 -0.270939382197376 -0.0847679759177189 -0.328936633111372 -0.164218101242242 -0.0912608548555751 -0.148493808785821 -0.383670433089098 -0.257822233803681 -0.26778186390274 -0.336793774862179 -0.354820733507211 -0.15195192817308 -0.27747788544274 0.0991368709286386 diprophylline 0.198842841223674 0.109997357373288 0.197162925816535 0.101921016088777 0.178603042500913 0.0040238125628319 0.168034651194997 0.135930328814653 0.0581550217047403 0.34700316362438 0.163695875413608 0.37341148616978 0.0485434046679776 0.359661157599738 -0.0382789932599787 0.12466358435959 0.253370693406799 0.103159866739549 0.141296996621354 -0.132009719654085 -0.101483626055608 betazole -0.252529346694536 -0.117242549660898 -0.0243521417308695 -0.124053914320589 -0.214100967388658 -0.141852877722566 -0.263747143085744 -0.112453055980909 0.114967353606823 -0.114894358972924 -0.103429089284765 -0.236462903643576 -0.140388128457562 -0.152187388266563 -0.103703639540913 -0.246931348266835 -0.0565182318849926 -0.191565489027632 -0.280809502984529 -0.193085471673196 -0.0753172263167942 triflupromazine -0.159338621953375 0.306635687402693 0 0.187899098122934 0.229894484619146 -0.344534374325663 -0.16584939853325 0.151434896840336 0.34667043273534 0.118823139027671 -0.00958147445693325 0.122072545852098 0.298982507182605 0.325511095562787 0.178662655728188 0.351859952939911 0.187635341996665 0.310615406711109 0.355093307939593 -0.095367317728139 0.282653391361912 sulfacetamide -0.0457627490746478 -0.18636038830484 0 -0.173911802789828 -0.0358872625382906 0.0971475393010433 -0.107801909065965 -0.134003147527746 -0.119101161826662 -0.138221575636222 -0.0937326573330003 -0.11795560088985 -0.177802422662546 -0.0407380056305332 -0.169581308205356 -0.215006242889535 -0.389561931402635 -0.180778684455115 -0.217433481513247 -0.345066420176995 -0.271504035728617 noretynodrel -0.118594028011938 -0.314192721014358 0.274400375195757 -0.324988420823236 -0.349938681052929 -0.348287277713615 -0.0983323925321523 -0.451445959082567 -0.411545556249934 -0.418284702347321 -0.322662554296708 -0.260126286089285 -0.315299369728217 -0.468943924586743 -0.490905431955509 -0.330568548595221 -0.296099936359617 -0.496183436546448 -0.484587778526295 -0.337939082236144 0.0169741084762842 triamterene 0.00182864811304713 -0.0193090281028593 -0.0262027930621182 -0.106857804205854 -0.0203377140580264 0.222027662790744 0.0105551029652556 -0.0806550681492631 -0.168543191059067 0.0174368711775458 -0.0943772971369366 0.00486515072685645 0.00315895601070921 -0.0266932078291702 -0.0289101417501822 -0.0797060396085286 0.0873542780532511 -0.020396327827714 -0.0273220199715398 -0.150222258138272 -0.203040462560667 isoxicam 0.213377269931586 0.400625170703172 -0.215928513202754 0.364744723010075 0.51818443942216 0.238455110001023 0.386855938681791 0.513716376916493 0.188268904866764 0.521955075184997 0.258091545159441 0.503039800698568 0.674714039673901 0.33058521195964 0.528828318186953 0.539115952463666 0.356981627938297 0.482580167632921 0.422115897276229 0.303063125071034 0.506036436099788 mefenamic acid -0.127013303579182 -0.118017455205741 0.208739189108935 -0.102764579712676 -0.143102087432536 0 0.0468774720509884 -0.161756361481026 -0.0872953855769491 -0.143503005620983 0.00501465375983112 -0.118791489366171 -0.135761662600389 -0.160822742069569 -0.133024919820282 -0.123018699901949 -0.0398975330075318 -0.149224270315286 -0.0315390709606758 -0.238209300307107 0.0638374622778326 atracurium besilate 0 0.654141633103999 0 0.593974032714974 0.474687056323883 0.404081401513784 0 0.296892475039354 0.429502141177597 0.465545566309162 0.203624063932021 0.319930847921168 0.379653968967282 0.502634489959133 0.510730806512157 0.485780796883469 0.213266308073218 0.481138175287203 0.470114457003061 0.378278788353496 0.201010532323471 heptaminol 0.107743097308587 0.612668238390859 -0.118814258586198 0.571009313965633 0.590172399459074 0.333197636483087 0.394887514191667 0.427841672825542 0.508863063051129 0.657416673835713 0.368082008064035 0.557698882987983 0.608031729373493 0.620692803983171 0.697343881749018 0.581865063756527 0.515185641579453 0.536175158967698 0.693026600118078 0.249685900296999 0.200454921325931 thiamphenicol 0.264388486843964 0.670793646713889 -0.556966537760992 0.611411793355674 0.610964431096788 -0.021514923295976 0.081325150475588 0.633236829939886 0.50901945429088 0.590492218655459 0.414068661157936 0.57072732166571 0.713170343872332 0.714730419566384 0.718649604264568 0.693168374020151 0.420717128200589 0.529098631675261 0.698634507085517 0.354153991244585 0.359918602402721 dapsone 0 0.4967698413352 -0.228071603117 0.485466041344085 0.461748848850498 0.107275675837735 0 0.473068144658608 0.478398343325134 0.515513046537161 0.292016943846525 0.457664234781981 0.514953180191775 0.515549080139944 0.525551487652432 0.518780998220409 0.497918809076868 0.498116422290174 0.55283300306323 0.278812690309135 0.416263227725564 naproxen 0.0541226363641175 0.271599660898217 -0.129951782692544 0.230589221387515 0.270281133413546 0.141144192488221 0.0902367232873604 0.283016253427298 0.295187139593319 0.25659371546184 0.0811279689172445 0.231168070934193 0.325101289549424 0.23851313237984 0.270028670501785 0.294250722217803 0.221141244721116 0.15061960558813 0.209756289153724 0.0492788465490765 0.249170479112037 acetohexamide -0.168771638685488 0.00153568449873592 0.132260371113058 0.258362793338628 0.0235350267378145 -0.162582564122803 0.319072275163511 -0.125332311416784 0.0555723415328826 -0.177563376768091 -0.130614954589589 -0.0898868865983958 0.149289514585231 0.112988097210629 -0.121847118998852 -0.0015433501755317 0.145905396459174 0.0208450907492586 0.0743928595756689 0.401751374002203 0.123334830982934 diphenhydramine -0.111775934328307 0.533333793957335 0.147953122681641 0.569925294368342 0.443842093194372 0.0592975665109855 -0.0937535784842335 0.449443782348799 0.536842397632221 0.572674670390808 0.32927853156933 0.519232404530983 0.518676553614732 0.506086988288853 0.500932629081207 0.500701526400887 0.249337554675723 0.490619097312843 0.650076329531665 0.0542234260122268 0.135809663879073 adiphenine 0.150700146078256 0.80815251503744 -0.185682399686183 0.755629068452958 0.716539561073449 0.21057857986345 0.151179105505427 0.759588840833176 0.751030710998533 0.817897261526855 0.647405062058595 0.741559313492963 0.835218917626038 0.847788907675593 0.861459348053264 0.834544517317885 0.748975444258636 0.8123666186542 0.882591302387803 0.279789665592248 0.70955791227953 piracetam -0.0221552117334283 -0.309891748867497 -0.0609765832778502 -0.301167054443802 -0.325522908402835 -0.446925891904761 0.00333549417955994 -0.240868581435192 -0.0930854583401943 -0.306244631525783 0.0280582582893331 -0.146441684607341 -0.329718379726322 -0.195160134979004 -0.174229280170305 -0.278177547755537 -0.0228088328782128 -0.297220199916823 -0.291481684207743 -0.199889418892878 -0.141242065417948 molsidomine -0.00355115994919943 -0.236424933872407 0.0691496222376115 -0.245367381683139 -0.185521084393892 0.186798528604278 -0.226780952815116 -0.194675684260766 0.0272137737525829 -0.393747912489664 0.0146232609164081 -0.109741984808493 -0.259717592233629 -0.109165153443406 -0.242281038418052 -0.212683887870102 0 -0.231100661055851 -0.0535058266838352 -0.0274402041884133 0.0333890283983427 dirithromycin -0.340256836410445 -0.285649436601215 0.260665189537064 -0.266400177822537 -0.344378266731408 0.171692804125957 0.166782319475062 -0.251310999048984 -0.0489774330972614 -0.274108631224868 -0.313513165643195 -0.0753974896647761 -0.155729282476704 -0.270382963235561 -0.283547415096988 -0.276519543809427 -0.349855415400218 -0.140230568493091 -0.170646761169448 -0.188601409356582 -0.265897343664971 dosulepin -0.26006061779513 -0.218427543845603 0.230176715139 -0.134056486763154 -0.392929648890816 -0.301779408572824 -0.275285540633337 -0.359502802095045 -0.18212297237793 -0.27072454642713 -0.245907924771172 -0.13009077546472 -0.268763593711211 0.0315174884510585 -0.230460706843253 -0.100922206624838 -0.0910404326438629 -0.258260070636599 -0.248006530268174 -0.186405064031979 -0.257663320133143 artemisinin -0.350986988107667 -0.475537737587341 0.448562873073727 -0.427186656608028 -0.555134909630705 0 -0.291119358130558 -0.580569729285289 -0.384792957894577 -0.492845484173762 -0.237014932724116 -0.608126040392155 -0.481820495211873 -0.667936337099011 -0.651034390855481 -0.49347026496601 -0.210760744696285 -0.473697013631358 -0.36586925406508 -0.231193616178252 -0.403754400626167 budesonide -0.233683493961829 -0.52509416804054 0.00837418864063756 -0.385543977316144 -0.428950440753872 -0.163896024029435 -0.222404386751982 -0.478215744133616 -0.451212798608726 -0.491167078650757 -0.293468790875765 -0.589499468247971 -0.550933579836005 -0.42047924364149 -0.408925782047024 -0.522277265473364 -0.415987437236821 -0.594572640415951 -0.54639822744823 -0.412443804478094 -0.421135550779606 triflusal 0 -0.733673924812907 0.272216348118824 -0.638411211407865 -0.719059133376726 0 0 -0.731998105150118 -0.697661688282898 -0.760600609805354 -0.547003194570085 -0.684302484922294 -0.728178204985802 -0.788220164621359 -0.753490033982737 -0.734534123020309 -0.618027482498646 -0.734902166831924 -0.803589097057236 -0.385136524808182 -0.672963928777077 phenindione -0.20913793189827 -0.615983736470581 -0.0579153665889746 -0.460659063575096 -0.498818507539819 -0.254140741089774 -0.144766174632244 -0.638441876109211 -0.582789922667645 -0.628564702520314 -0.339078417128403 -0.581151786334276 -0.637649153749797 -0.641567566508234 -0.665769514443771 -0.515089845387277 -0.504648306793106 -0.611267430974736 -0.648120223977283 -0.483929643743235 -0.311355611476227 chloroquine 0.0507694508758872 -0.164391663063991 -0.144726180068518 -0.228756646800611 -0.132934887813259 0.11065421278263 0 -0.203545796538471 -0.143807267722124 -0.0237549862522602 -0.188827594273286 -0.00729099673433671 -0.499165628180424 -0.0663339145584656 -0.198787048858492 -0.2882757236372 -0.22770598285412 -0.385362538651138 0.111617285853691 -0.0433240509152956 0 gliclazide -0.300590430532738 -0.699149058069484 0.281888440751132 -0.577569538550212 -0.719240754143217 0 -0.142591328871669 -0.710597125100018 -0.626993209034128 -0.722081549023648 -0.495009482321799 -0.643927652436688 -0.711960553193334 -0.780011869000936 -0.72812096394062 -0.720036315521353 -0.542991000435039 -0.693597993055069 -0.709303711551564 -0.383954192863359 -0.505473514599755 ceftazidime -0.0226366051930782 -0.287151732518339 -0.0805146562772442 -0.107122468194933 -0.176121512420129 0 -0.181475190144589 -0.0738449912155642 -0.145134718427697 -0.284096041162004 -0.36077583316826 -0.23618536326191 -0.369643760489874 -0.216089191513821 -0.233601367553298 -0.257534378742189 -0.3721801001101 -0.224324771197653 -0.298976981627568 -0.104897840607164 -0.221380596538824 propafenone -0.167215241166294 -0.59970023890259 -0.138321669816224 -0.555242997173607 -0.443206677249932 -0.320750210269571 -0.167384949891481 -0.547344503734348 -0.461288516629575 -0.698956407546398 -0.488135860872246 -0.650673646345192 -0.699419145821875 -0.684782795751182 -0.657463364201009 -0.664256532992425 -0.546439693403612 -0.647414624619147 -0.6676985423976 -0.262029456884798 -0.402746475115074 bromperidol -0.105946494007578 -0.424580807727496 0.352473065427115 -0.542346950030888 -0.578595439114787 0 -0.189137955296181 -0.456209310654938 -0.610345064544982 -0.529411698289341 -0.49705049434079 -0.466056493045609 -0.545687561332143 -0.550386283617659 -0.708794607787787 -0.668520555089964 -0.289067588095588 -0.420283667384727 -0.547723585998574 -0.414729392475263 -0.595200248133382 imipenem 0 -0.621935365361847 -0.0111196480890291 -0.500366541490602 -0.634942991514286 0 -0.240533648032202 -0.676673075624173 -0.592082850556851 -0.635449198982183 -0.374600875572424 -0.567937484690037 -0.683732135276026 -0.681827176839527 -0.688413139721932 -0.649285160135427 -0.503066930910412 -0.620042695861363 -0.669323528065909 -0.464835021675365 -0.612315141985616 mesoridazine 0.047477635074521 -0.313294374032911 0 -0.193979460420378 -0.319573698364806 -0.236321328310945 0.0275228741186899 -0.451457994111362 -0.389952378708384 -0.175956813416799 -0.407457657013727 -0.256135136008777 -0.195039255066491 -0.331711771734839 -0.578205606026297 -0.444840984596696 -0.381948889525485 -0.604111274543884 -0.358201743075384 -0.237922349337731 -0.370447808422012 thiocolchicoside -0.530674518596564 -0.543829409742751 0.251999529095717 -0.288985317694686 -0.605390751354519 -0.499568404988353 -0.126310038883817 -0.572210403647595 -0.50425169653986 -0.554636062213584 -0.301106260034834 -0.520027796687817 -0.609747029620876 -0.520195630006746 -0.592590137799731 -0.465887585448404 -0.103788145030133 -0.564859519324708 -0.247565642771996 0 -0.481349970027872 trimetazidine -0.171955072722759 -0.493450541353462 0.10716481057942 -0.381232243133235 -0.498369317285445 -0.129335980709461 -0.344197992718456 -0.546821122324839 -0.422757373719621 -0.495039041311338 -0.173106646296925 -0.522233024657595 -0.64221052832821 -0.513650433786828 -0.597382672901925 -0.606297907194186 -0.256989280576982 -0.589668227799618 -0.528269537301373 -0.138424694359286 -0.602976350558071 Prestwick-559 -0.425606201811181 -0.734936846986754 0.279646935089746 -0.517516629567957 -0.761817719522563 0 -0.388828016198426 -0.724947508580411 -0.647869219912964 -0.715095337260633 -0.505072401686987 -0.678202574303939 -0.747815235018004 -0.758000835113063 -0.717380309150547 -0.734495944987923 -0.578590680551176 -0.724086966235645 -0.762597252337496 -0.589286769690903 -0.729247587022137 iobenguane -0.0645134688785203 -0.235518795668185 -0.0889008055911133 -0.316322681976425 -0.0270462962936214 0.296532183792643 0.0335648590758035 -0.178509999663383 -0.141007829364144 -0.398688582679047 -0.109535889732439 -0.155864548650035 -0.169983870520163 -0.30018187814365 -0.451686085966443 -0.414664694058465 -0.439482563142021 -0.405398855046908 -0.40850844567545 -0.208562104682625 -0.396634143338412 etamivan 0.118700437582057 -0.499922703899869 0 -0.131655068660811 -0.370963999780425 -0.0287460162159761 -0.15187239458681 -0.391354371639565 -0.366656501759729 -0.548602305894545 -0.266156199711033 -0.257074048092853 -0.56214152304995 -0.430657610817083 -0.565361452537383 -0.432317315952045 -0.23704810974005 -0.53071216904225 -0.440959184794997 -0.137370512616926 -0.246942681464494 cyclizine -0.370411004359525 -0.21869161964296 0.283356292940656 0.0533116241063749 -0.182552386731747 0 -0.274687812501541 -0.27265037702803 -0.200161146321764 -0.325792425316625 -0.115690285610677 -0.265423884557525 -0.259991804447789 -0.247333503910777 -0.22606188715429 -0.222637094598168 0.0270799580488816 -0.229431602513702 -0.126249376831426 -0.0169752788025838 -0.0165473001990258 Trolox C -0.0594987565046229 -0.400556589478509 0.114385868059342 -0.147239725874453 -0.227303514674376 0.147926986221314 -0.140639399195375 -0.334380228310684 -0.289492946508906 -0.188571682315203 -0.0710606726375578 -0.177480565397758 -0.228858934139099 -0.327906050519495 -0.298899350589436 -0.405377256132127 -0.441776799780857 -0.37667986024147 -0.211270718902073 -0.435648865867969 -0.282603370242284 clorsulon 0.0751826683894802 0.513349328832157 -0.272913895225443 0.465576984707284 0.573511423088278 0.444303862323872 0 0.471917711205003 0.312541593093374 0.479895503513903 0.250309112786993 0.337934839558062 0.529681116897506 0.652021296365096 0.655321893320256 0.622567507235579 0.287956119873965 0.477571723575063 0.534616976312569 0 0.27472357767124 parthenolide -0.520329759307371 -0.200708557219838 0.234224372332903 0.137604858267481 -0.342025232086734 -0.120629471565782 -0.271061115783082 -0.316609971562344 -0.29823681269199 0 -0.241430503907793 -0.116947881547148 -0.469765595628896 -0.511176495866345 -0.340180019290023 -0.13871568803477 0.135413498449134 -0.353068109535938 -0.376622527964321 -0.219382289807565 0 prenylamine -0.567244442646406 -0.580404897840459 0.119202825689341 -0.377868187334748 -0.450765106092517 -0.465466554348542 -0.448927154263526 -0.560637900374061 -0.589977967734005 -0.6035126741073 -0.669369683106703 -0.575062837738023 -0.688829192734119 -0.679479487547444 -0.692769548014583 -0.590124408219466 -0.525383206589915 -0.659925514949908 -0.589371149593304 -0.548157346175507 -0.44256872759191 tubocurarine chloride -0.034615687732632 -0.0726420074605441 0.116974743604457 -0.238603190740297 -0.157738457411786 -0.0788671084339975 -0.199557639905523 -0.17137758116746 -0.189343948161981 -0.220124811386452 -0.183371383348562 -0.112912587616118 -0.263326938137475 -0.127202721720328 -0.196720869701139 -0.08174832258582 -0.100518165926716 -0.289997224935651 -0.301540332068872 0.0840079914928532 -0.305500504944436 tetracaine 0.16645989271779 0.252883507170446 0.154549347210688 0.200523843535093 0.0748377264440096 -0.444916279100036 0.248810841230836 0.144669407818914 0.256955396216364 0.316354629464542 0.0392948617835381 0.281110732419526 0.276738270347881 0.279691555913784 0.242059401503973 0.238927130789161 0.271356520369804 0.183602102806668 0.218730152959425 0.038951456291061 0.258174194852708 hydrastine hydrochloride -0.220292141996173 -0.510463416929576 0.210079499947773 -0.25687729177468 -0.327233108120187 0.115652050254394 -0.112518320577281 -0.428538107986723 -0.403315993956016 -0.492458701967977 -0.370475690592237 -0.26587128644003 -0.528284434046161 -0.421760970184716 -0.552039743434762 -0.416095848511069 -0.373897203795716 -0.449720340062552 -0.436231684010224 -0.174120860269226 0.117708692849426 laudanosine 0.178232287112273 -0.0672817359218071 -0.0258409188688423 -0.0565664364274459 -0.0748327743472809 0.123766082603998 -0.121087624281765 -0.0501298472093612 -0.144419379366303 -0.085002793799902 -0.161496546036378 -0.201906379073429 -0.0362622971706126 -0.11559514929997 -0.0549423792581686 -0.0797472394794288 -0.236872714897637 -0.247003192842955 -0.0959240002163839 -0.301837988308217 -0.234856870870598 scoulerine -0.5855212481799 -0.215165772622796 0.303209558325773 -0.0970258685988341 -0.168777341409898 -0.273286391146751 -0.325926387837712 -0.0936207695604522 0 -0.265383124804499 -0.0434729538538095 -0.221257803958705 -0.367181223541637 -0.00897407871343932 0.141421278645535 -0.0480543608020405 0 -0.121017965989047 0.016538836828526 0.0328696259480033 -0.261558898701994 10-methoxyharmalan -0.1134343223724 0.00660566883875564 -0.310181451892089 -0.180793221358995 -0.0779729761516561 -0.208244317454171 -0.23488190359706 -0.0947284231046304 0.0763929426571702 -0.0993028940086103 -0.0544903444558533 -0.0112714456387325 0.0095444722936644 -0.0162105561301774 -0.0168524965117469 -0.103136073656639 0.0955601815298066 -0.0271966736516164 0.138033530435502 0 0.0885039712712687 thiamine -0.115774785218388 0.504387857476968 -0.0795222466083937 0.523834106777449 0.1033296467811 0.0545122616838466 0 0.319521176799934 0 0.2121810956663 0.44127911105275 0.180618471708519 0 0.514357699473291 0.325440521620593 0.381100730821408 0.177652085764222 0.179703724059204 0.417664619696465 0.371465879179448 0.231956933571317 dihydroergocristine -0.167408791666546 0.347511358283404 0.116695943826046 0.327379054898572 0.393925266763908 -0.0316836090211519 -0.206961955144448 0.40193586235268 0.136658152768444 0.350325294491715 -0.114504561976012 0.191845844438546 0.467279089372795 0.221918936789176 0.419965140516251 0.197322920059929 0.138218282896896 0.183093448700191 0.364012340662126 0.00781815620716395 0.218928400803607 mometasone -0.0527596316090057 0.0182711479896025 0.111488585938569 -0.0446534943937433 -0.0449044316725935 -0.0254470647474138 -0.136778952459812 -0.07793538429606 -0.12362854796457 -0.08506811258314 -0.220397690143282 -0.0594243016964935 -0.0452495936611197 -0.0079427138590174 -0.0785788563493323 0.139613929650046 -0.282131889193153 -0.143342439658903 -0.13181459628823 -0.217659315603179 -0.102725696469054 lobelanidine 0.0523353067121826 -0.0452577017539267 -0.310901988144617 -0.00749966769965513 -0.0409953765973364 -0.141438251705933 -0.151305713994189 -0.148915264681267 0.0616008272676002 -0.000771738983072867 -0.100871080687238 -0.0348143164488581 -0.198139208108448 -0.0300783117237864 -0.122591482579921 -0.105708298329919 0.165662376088669 -0.234678698646726 0.103068841551823 -0.167671156532575 -0.101074252035636 raubasine -0.109922551790335 -0.086785282786497 -0.0456157264528548 0 0.0387307415713411 0 -0.103067834929848 -0.165494229782565 -0.0949035208054243 -0.0066425879641217 -0.0862801877782496 -0.0423598090388008 -0.132729621277429 0.229678481770219 0.0219892173393986 -0.0966197799933754 -0.00942190238957809 -0.0134179773035934 0.231308429018888 -0.27408630970611 0.131314544618056 ajmaline 0.198688853988348 0.506102209792768 0 0.549331427359618 0.600867136381047 0.331051135626873 0.381831376957897 0.630764034066907 0.429336030680943 0.644161049234587 0.411635164607234 0.66079484411238 0.685339898747939 0.667410521676975 0.686706361969486 0.640743045227837 0.275302165486199 0.588668905677043 0.608243553673916 0.304674534545894 0.437228426558601 harmol 0.27819592217015 0.282191797759589 0 0.317949417999018 -0.0528703373780606 0.142960881247181 0.25 0.22028299574115 0.429494071341924 0.382797392954782 0.367619081380263 0.414978376376481 0.26242210843006 0.268313682625939 0.229042009243181 0.3309785078755 0.230548086606318 0.327919410926452 0.184413455222986 0.35521548120055 0.05125601948981 stachydrine -0.179394563564468 -0.00921057162431069 -0.00664236516828182 0.104889777480527 -0.127293648814645 -0.121935183362283 -0.0092836723105493 0.0980570100104055 -0.0782741574901171 0.111042416393041 0.0326811012564466 -0.0542967011252437 -0.0462726380574709 -0.0547229192886728 -0.122402331395057 -0.0423303706975939 0.0933935058243744 -0.0297012457994663 -0.0672118375069149 0.160605760793954 0.184905403019327 dipivefrine -0.210302792789954 -0.15304447312126 -0.0310270007498037 -0.131970008672877 -0.0497122392206377 -0.0288955513664196 -0.104700449926499 -0.171280456554907 0.0702177704741733 -0.174653083453458 -0.141863567499067 -0.164058893328216 -0.194863229175704 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-0.0126390666818915 -0.227113815200149 -0.483949935500638 0.0842091160155489 -0.450025899764012 -0.565072723704873 -0.340345011952865 -0.49493649249483 -0.369682574471153 -0.459848860355218 -0.609416189745564 -0.622244787318998 -0.489551306967915 -0.406188598248261 -0.300741995734041 -0.440593403700173 -0.483949380643612 -0.367771253151681 -0.279419086902141 tetrahydroalstonine -0.00411259360987991 0.250769233359744 -0.188323452271313 0.235673662323591 0.256944978650479 0.168466549700545 0.0613602562426155 0.150031008904777 0.0766746571187801 -0.0154810970274994 0.0220693404680488 0.171009434098244 0.248031666214408 0.247755086861428 -0.0399108986066001 0.261740497472427 0.1823705617932 0.0208330959839037 0.225507004074237 0.0371893479832091 -0.148245694474306 monocrotaline -0.167651030753513 -0.372624663633194 0.109858188301752 -0.474883393630764 -0.380731654186367 0 0.0412014953149665 -0.410096057742935 -0.26071372631236 -0.338646619578521 -0.1991055932097 -0.305491211201523 -0.382172778297812 -0.387532563531867 -0.367770324376126 -0.369547526283364 -0.249668657869879 -0.310988515101574 -0.381321339537188 -0.445176595902113 -0.329717115137596 harmine -0.142528936908582 -0.570239819330099 0.0845863020351941 -0.49559690295467 -0.719009502326046 -0.0571004278036785 0.161378397172506 -0.645564340672144 -0.449154067981128 -0.596545452969209 -0.195240601768567 -0.402296122124517 -0.459915595835151 -0.486808315460247 -0.583789139477233 -0.548787652317949 -0.29497821137231 -0.419989786531701 -0.625711915230555 -0.33872883014085 -0.527953782270459 pyridoxine 0 -0.579019484549546 0.178058820260647 -0.426703318874278 -0.645346443536947 -0.310480767070295 -0.00516410408828227 -0.494928514402143 -0.312602324441884 -0.530997836550636 -0.355729761311273 -0.491246979277169 -0.574330958025621 -0.723485552994235 -0.561778119893656 -0.673742817067595 -0.214097928968388 -0.443645032924097 -0.465332880573167 -0.471401876655946 -0.224862715305856 syrosingopine -0.328748246064632 -0.19213254872134 0.0155264016392551 -0.0516847174250797 -0.240224738172529 0 -0.446318065690509 -0.141789515105422 -0.135492572498532 -0.262202024290371 -0.163782525133768 -0.325568303609384 -0.309954394522917 -0.274316610086457 -0.353547084936919 -0.235514130911465 -0.405295423878556 -0.229177206213281 -0.117875986257434 -0.264859091937472 -0.171292441983775 dacarbazine 0 -0.436608758554708 0.228109968562461 -0.374519292602289 -0.431452314352304 -0.213852095672474 -0.26787104025248 -0.410266336632374 -0.392511230139525 -0.446352381819262 -0.280439934865315 -0.372510983483898 -0.440687720221451 -0.479492279098841 -0.393502672696068 -0.456057410939721 -0.474307653811218 -0.439768670954484 -0.438149694153357 -0.30960310353316 -0.362740430585605 piperlongumine -0.352199246536854 -0.662157763451106 0.420257916529256 -0.403673293984984 -0.641647668009176 0.404349727403273 0 -0.683920335750228 -0.705476417189514 -0.706776020100369 -0.546372947817776 -0.587150073196337 -0.752424412051619 -0.824686231621515 -0.835012330971172 -0.698136043020961 -0.636995541507514 -0.745958381462507 -0.831310395472233 -0.303021134780726 -0.661703315153391 ellipticine -0.260250667546193 -0.675484806086443 0.125035112540586 -0.494996916635427 -0.591422865031753 0.136420611202167 -0.491816437334972 -0.691358925616876 -0.553267203447591 -0.714510270373087 -0.451685437677539 -0.644845451645402 -0.726535260208961 -0.726364473550101 -0.730194919338313 -0.518547127925647 -0.416215354425435 -0.668892137721018 -0.683097468165463 -0.449808688596366 -0.602735774049962 cytisine -0.149306479384103 0.229544519110101 -0.370029176871571 0.22222313846112 0.179091351138589 0 0.0504082636677481 0.225120887300618 0.297548737672627 0.0926737460103909 0.31521893612372 0.146337974614092 0.282518273862606 0.271347915305481 0.279145072595176 0.269387483851364 0.209116636543128 0.252684515376007 0.205396329362928 0.147632495716507 0.274233680102562 riboflavin -0.127600451644208 -0.624528616355029 0.0790345335536488 -0.47442116325758 -0.604490872257049 -0.289265904774453 -0.270445520389123 -0.633163579021024 -0.559365024368087 -0.675769825252023 -0.455374447230109 -0.60126980975904 -0.682243175454755 -0.688372356100262 -0.684757779076927 -0.644062103676808 -0.416768541888539 -0.607877172312943 -0.701515119961433 -0.133650248627582 -0.600279109707964 atropine -0.224230386640602 -0.545912313710196 0.128379755087762 -0.393434133551911 -0.546520873237943 -0.343672435894783 -0.343709201558469 -0.447327601255868 -0.442894959923239 -0.498159310994705 -0.399247630586634 -0.434168071575011 -0.635968707399193 -0.43105072892714 -0.520659643205339 -0.42772087018803 -0.143049045777478 -0.525507455374107 -0.618597785288313 -0.262649359138835 -0.290873848165272 ipratropium bromide -0.168988489583786 -0.65460429676727 -0.0408024829702882 -0.523956796868529 -0.624964652432884 -0.286580262814636 -0.348981061474405 -0.632372139426531 -0.615911853103459 -0.676059667826539 -0.471449652884553 -0.614889202214775 -0.652284874759817 -0.736739764308021 -0.689974567096791 -0.627573227076613 -0.295687700532698 -0.504730423855035 -0.697313893727496 -0.200875349534825 -0.444171926442395 lobeline 0 -0.110746987813787 -0.0517339211149891 0.0629513158983966 -0.0237200762268998 0.0213272394394901 0.1483227276734 0.146641256040004 0.0126422356936732 -0.0305969288772543 -0.139035231201934 0.0068272626579684 -0.0091670773535584 -0.129108866417455 -0.106243994423844 -0.0319960350532112 -0.175685527060371 -0.0392584746816456 -0.0532648562575504 -0.0859574302852274 0.00490543490231088 calycanthine -0.0878903806571981 0.0914988133797091 -0.201124355910589 0.0469349391213137 0.118896057427601 -0.0933086690907347 0.105945669859427 0.160270383332323 0.29183249157409 0.0431647442476325 0.122495919337246 0.0821484036712095 0.0774843340662981 0.256820622990977 0.271873816445473 0.0702310332169964 0.0142896294204633 0.0222472624170586 0.136912928083338 0.0417944317783872 0.181654678251189 hydrocotarnine 0.143907839485727 -0.445740751970176 0.158502447995726 -0.370627561351388 -0.388884711580833 0.0467955201512982 -0.156211131310292 -0.397100129928866 -0.428921449756209 -0.484719280406399 -0.369756443402324 -0.394158991781114 -0.431614930091537 -0.448087254585676 -0.561749010992968 -0.406880365338051 -0.314238993435191 -0.496475920072326 -0.576499502028362 -0.287696480234823 -0.103993401002783 1,4-chrysenequinone -0.680942193794347 -0.647398539091296 0 -0.555529624498215 -0.548767398311304 -0.263653798795896 -0.585136591944518 -0.61894356128896 -0.660522068366479 -0.60780869337141 -0.588661296823823 -0.627188764508578 -0.715277968244068 -0.770342668809512 -0.778285229655476 -0.721944343224153 -0.644395878321681 -0.683169962434157 -0.754486978327805 0 -0.341706383303936 pseudopelletierine 0.0131675407825704 -0.584422648388953 -0.322110342672456 -0.422681071192462 -0.448474844306319 0 -0.2116943807757 -0.477169012496257 -0.343000983542255 -0.452319190313604 -0.297362129684108 -0.324712939631636 -0.3777574529285 -0.513201480450358 -0.359681861133887 -0.596728739300721 -0.541605634809347 -0.460892711347336 -0.586472562929419 -0.419444085579462 -0.193238790811543 hydroquinine 0 0.287474555323098 -0.193240605288679 0.224961258980763 0.303199810695931 -0.167456804035313 0 0.236240219659678 0.402357981558174 0.083569959772722 0.0408955722044584 0.181892915633401 0.0332389614286566 0.042794577876308 0.0345660450609309 0.162785479186722 -0.0440674730809544 -0.0324027754743862 0.142842491283155 -0.00804727614047766 0.389645202201891 physostigmine 0 -0.161612151540469 -0.0620353535266035 -0.13023174145985 -0.156311239308213 -0.265475960786455 -0.144911791259721 -0.172837316159799 -0.0110682538504959 -0.266618680607039 -0.101097429873014 -0.237148205275457 -0.222176072660379 -0.186072035002246 -0.00930107919956716 -0.171277071654645 -0.157164880197899 -0.0417590310293151 -0.0452323820423729 -0.108585415622818 -0.272118675129988 acepromazine -0.441644201222972 -0.654638743321181 0.161140849087058 -0.545226058671391 -0.566809989968261 0.154363250336948 -0.310811065105888 -0.68383853634682 -0.615920375812823 -0.633851424717304 -0.523677635337344 -0.620962022381249 -0.671234109369919 -0.674856957584306 -0.721322709266048 -0.645685985194104 -0.578031039688282 -0.652453534708354 -0.739012386058021 -0.453661250700194 -0.518748013846174 berberine -0.0231993308275734 -0.607491567043623 0.23191725642686 -0.564916111628912 -0.563248654900028 -0.117538043880056 -0.324924674617857 -0.45468430992614 -0.455032741727739 -0.642436131166413 -0.350172472213872 -0.599248140669685 -0.635789294359451 -0.511952210726208 -0.649822387836761 -0.595235527489104 -0.54512655084912 -0.461454536371984 -0.651449257161592 -0.274483571008327 -0.432469814410979 convolamine 0.249209662804965 0.143477253684615 -0.0381601895929216 0.330664260806238 0.125602019188008 0.162053128258134 0.105559983409127 0.0170179495505008 0.107873617395437 0.240670685930885 0.057581643162382 -0.00740706246676424 0.0199453443067635 0.0948091762253862 -0.157540575992686 0.106846605875373 0.108124465771766 0.106139035458444 -0.0610667252192248 0.0816076532749383 0.305763770495854 cinchonidine -0.123649608843335 0.0400586991314705 -0.0625983136823745 -0.0907368945681814 -0.0579901031525455 -0.303029486923163 -0.105187627674266 -0.0406872850224836 -0.0790663883767772 -0.173858604993099 -0.158464100765868 0.0306034562471634 0.0570239403738891 -0.00267591783537444 0.0268173419437628 0.0144964968290668 -0.0187812260413614 0.0420201959156281 0.0430924631202798 -0.0481844651349898 0.148906831241107 demecarium bromide 0.182940074487713 0.34329854050941 -0.0679200569376366 0.367752021302539 0.299443843915926 0 0.339911837617 0.296450605086093 0.314216490695848 0.365263139528281 0.121897491597387 0.367692712218657 0.467247610913411 0.219972655860454 0.320664151110815 0.367760328338749 0.10381811512091 0.36674436971445 0.229685112795127 0.165519749718179 0.264673739036936 racecadotril 0.41953614240281 0.272164490181606 -0.375298473257073 0.161767481472172 0.346358822517345 0.241187653558095 0.19716157200698 0.309383416254845 0.11719061911154 0.280404295362877 -0.0657348659092343 0.282838098278823 0.153693546615987 0.262487153880801 0.260798640969472 0.273891322868128 0.127606804300193 0.27695497475594 0.271023407319868 -0.116433320333232 0.146184383049801 epivincamine 0.124667615958748 -0.313662516305461 0.0907371270157916 -0.233819361595413 -0.195481609467193 -0.0802457992806704 0.0142339957757966 -0.196712911916135 -0.207824744451582 -0.306230411327902 -0.194404423544596 -0.137582501305714 -0.121534856977716 -0.243033774244461 -0.232758311835814 -0.305107628857231 -0.270721275206885 -0.339216000354923 -0.238502945063495 0.0370970648273153 -0.217394469954365 aconitine 0 0.111288518941538 -0.282239195137318 0.194625805020112 0.194827423971664 0.284096460705854 0.111241252678794 0.20785288311698 0.47077636323456 0.193716786881338 0.0366229323127876 0.146505128996509 0.237789125105445 0.116102788129433 0.220601024876217 0.144354242248046 0.276803715190031 0.350787170655484 0.129852077580741 0.0175529752890325 -0.0419715787161141 (+)-chelidonine -0.321927590429399 -0.0118209170721332 0.259069729161292 -0.00155804706500451 0.0790852265835285 -0.129750336096413 -0.179566125819567 0.128020197418412 -0.0610842131365406 0.192876186540919 -0.020141700601666 0.112738572956822 0.113488475284352 0.129531792263511 0.242606814309456 0.00903231490539044 -0.161615479721476 0.206028642011292 0.140186309810935 -0.258386103197558 0.0412141655087207 isocorydine -0.0110493743578238 -0.0576487311788555 0.18850054031779 0.053894378555778 -0.0767339579238077 -0.0386935794612487 -0.0571943356844351 -0.0272176606557297 0.136120797153729 0.165505852894557 0.0521943651690672 0.144492306204441 -0.0212474435500144 0.0327023351932648 0.083549022494699 -0.0159786487884544 0.122396130641206 0.0321793402624574 0.00386203514649641 0 0.052723359879977 vinburnine -0.114272964868934 -0.0233887635907333 0.271896810473247 0.0189378261026683 0.182149988654385 -0.166477142065882 0 0.18676491624954 0.438816828573436 0.429454259334748 0.249135406412821 0.192830833541734 -0.124275233000739 0.359075668161963 0.376359819979613 -0.0234619536805428 -0.0354311513708639 0.159976037980671 0.210821342978392 -0.194750850005 0.056518488967646 quipazine -0.161988556849377 0.133378448685253 0.21265338523083 0.0182437974593871 0.0986149648629853 -0.0562816740145324 0.155351996872477 -0.0254537149327235 -0.0112140919460368 0.0951027169583599 0.104429856155006 -0.0280936145638344 0.116644745469831 0.0113244449922897 -0.112104083030628 -0.0237080252043369 0.072094193420257 0.0287541505585682 0.216939216659716 -0.0485182640445793 -0.0380964828686365 folic acid 0.0595268445939075 0.387733818596331 -0.263202292053053 0.463932749501494 0.397971324234409 0.16520558209623 0.0763484689459638 0.432841203654889 0.453615593784633 0.36907814383637 0.248338861815832 0.388909458551766 0.541718472914485 0.409873164746882 0.343426537956954 0.442081970029131 0.152917897240476 0.35458437752368 0.190035245371054 0.163452973307101 0.259763350272986 chloramphenicol -0.0390226822186598 -0.559669171423759 -0.106758858533946 -0.367579839965142 -0.288942571749416 -0.24051027534786 -0.0711899387917515 -0.397310405299484 -0.318082188732073 -0.407491253887848 -0.323462815545393 -0.262048769960113 -0.4230501404995 -0.617184043645785 -0.590177765530901 -0.563230564467558 -0.533087347847202 -0.568862713581552 -0.633283731782077 -0.229479702681531 -0.412285825928438 isoflupredone 0 0.771891309711418 -0.0741325681783982 0.72067915252873 0.730803233936455 0.383639885230963 0.251423071788228 0.739189550141748 0.771897589748377 0.733604951920722 0.551474191264838 0.686449667729289 0.817827103298923 0.860231513782615 0.860983548531976 0.813355519547051 0.742220024495164 0.802784575312221 0.876556746041495 0 0.611701437004679 canrenoic acid -0.225612399598276 -0.324137599295476 -0.00938149765406779 -0.154003561290528 -0.293335148358168 0.103695623402239 -0.118216485584337 -0.335633672061261 -0.408163552220681 -0.332524366585024 -0.188871396795118 -0.284939375436234 -0.335100897189148 -0.374889364791638 -0.398121408476147 -0.35081904016986 -0.203469333525731 -0.311465824309031 -0.48398446532763 -0.119104132249066 -0.317353571065149 ursolic acid 0.158035620297245 0.0220401293157426 0.475929219610776 0.00333408678996795 0.0245002779205072 0.024460257061602 0.0396526536159606 -0.0055489623757905 -0.00526909970425961 -0.0428235078388809 -0.0846701089932871 0.03634795940144 0.00860484428912768 -0.165602929785882 -0.202006486632469 0.028170605570591 0.0440173748387929 -0.0310355426172388 -0.199919989186553 -0.0124608893685358 0.158635713447552 gentamicin 0 0.600657772777632 -0.109035025572932 0.561019743708464 0.463028358464035 0.0342953014474039 0.232723260241198 0.387907658581021 0.556678795029381 0.609571807845823 0.296601663581077 0.576183376100438 0.644417433866492 0.661495461287427 0.657378189753698 0.497218777619379 0.307361292587818 0.342657329375181 0.651732677681968 0.10494758507831 0.110219182451213 methocarbamol 0 -0.204542913563119 -0.0647227988805466 -0.152900990147236 -0.386299087619179 -0.0402517766475996 -0.106647007328291 -0.199421161735258 -0.355946975582316 -0.161619057313065 -0.194254208417542 -0.163436505274634 -0.146121132297981 -0.223295634959603 -0.195946986542138 -0.155336606053251 -0.0198316985465524 -0.193707257454277 -0.22767661120228 0.078045540350132 -0.226048087859934 aceclofenac 0.143731890902051 0.0435130281687974 0.307075566006516 0.0138829008778171 0.0609607772916895 0.162332414003878 0.169427254399313 0.00720434878750111 -0.0748421789183873 0.157128921672057 0.00185749423018017 0.14201249363907 0.0537717172732666 0.0359479718517991 0.00218960912474739 -9.34068535188293e-06 -0.144634306833787 0.0312656724420918 0.0147513436681617 -0.082432813924027 0.255791599516524 retrorsine 0.0165066139091128 -0.268364962232085 -0.361032639422074 -0.353766518293064 -0.132224778360517 -0.061031883404565 0.0858691041348625 -0.243914884690969 -0.377393057150879 -0.444072907844154 -0.0484036475915071 -0.343968029450798 -0.137958257135598 -0.415463856478232 -0.28743317554274 -0.296530052949832 -0.266925357944335 -0.301987401095063 -0.46822979620242 -0.132366124034446 -0.142522719027331 rescinnamine -0.395471964987219 -0.264443068074765 0.0560895901813827 -0.288424762353211 -0.327005349380668 0 -0.138866259666723 -0.322511092846691 -0.138570660222398 -0.347097422401554 -0.166918683237026 -0.320109872240028 -0.316244770305574 -0.25097326924953 -0.261081682867966 -0.248895199963253 -0.176159993643865 -0.421073459838817 -0.260428464565107 -0.253384204126652 -0.30931584288289 galantamine -0.0984020273674392 -0.420656394230289 -0.0397232561916237 -0.387826905486162 -0.389903402945022 0.116129458746595 -0.0295030943604229 -0.424066035946933 -0.197361871381361 -0.558540040859087 -0.156333218081878 -0.328816227578614 -0.442254661998102 -0.527660412984835 -0.310557744103125 -0.431925422655309 -0.352404120024854 -0.448421690326907 -0.556143107334314 -0.314037712585764 -0.347364985958453 xylazine -0.0838322523036198 -0.399467785847326 -0.161526966778174 -0.421676328416605 -0.426809111863059 -0.208910238060471 -0.189576329859067 -0.389404260512117 -0.377185574660256 -0.459275482574853 -0.427962509571132 -0.42336567515068 -0.412612224951728 -0.389246866325927 -0.522344622258602 -0.394241124989407 -0.306847199860262 -0.375095851433705 -0.429729848610339 -0.261404125232647 -0.503137240296885 cinchonine 0.427546161320935 0.397914579923031 -0.212431021375945 0.119985701733624 0.287886312348433 0.283059251945484 0.342673042232571 0.492649472102683 0.484209551497791 0.313821317402739 0.346260651918727 0.184274210802647 0.493514058413523 0.452052298689858 0.286372572762716 0.175551590535827 -0.0404728521288915 0.263726504208859 0.0631211916162428 -0.0577582479034729 0 sparteine -0.0816400504229096 0.0261559489896594 0.267318669865353 -0.143598951549437 -0.196380497541274 0.153559105522681 0.295566277450891 -0.0596940597542166 0.0125375739207435 -0.0609846394521907 -0.0411066747055747 -0.144745201928523 -0.0109989680838567 -0.153301113457245 -0.0599029332090981 -0.138846135838934 -0.0509387001330076 -0.158714873099955 -0.182506686306825 -0.125655463769726 -0.274699046542972 conessine 0.170507875747148 -0.197912420382056 0.163781893866135 -0.102062868712663 -0.101298941313989 0 -0.243982705670677 -0.119488323596029 -0.145364277180193 -0.253063206526434 -0.170814666957349 -0.0790374692918768 -0.231060209156689 -0.227280034401079 -0.152787870517725 -0.231916968660408 -0.137270143024821 -0.102233774644219 -0.219601108113228 -0.242315015972413 -0.301934766608332 co-dergocrine mesilate -0.174075363891372 0.337368088697997 0.0141214582571896 0.181259102887406 0.359325396100299 0.460995995178977 -0.0670371951639467 0.31892887686632 0.281214418491026 0.275374423000328 0.0393103202769617 0.0743514135020256 0.315867031335365 0.350046323159856 0.309065392023114 0.185699370182329 0.221577008869208 0.242338300641555 0.173468300652853 0.0518814290899698 -0.215379514318361 palmatine 0 -0.290113284766131 0 -0.254458410263409 -0.143186192873337 -0.107931798797404 -0.187843113789026 -0.269453729918522 -0.250459715103377 -0.324589757384478 -0.18930186546245 -0.234135173762577 -0.286755976053392 -0.33119363616295 -0.330823735228194 -0.310410138084345 -0.280154499110188 -0.306333515781985 -0.397116454242256 -0.103847767082451 -0.322820282265058 bicuculline -0.0756557743891652 -0.239115549449411 -0.167507565297444 -0.296737657600222 -0.324488112895251 0 0.274134623807547 -0.230934180706602 -0.12754448233873 -0.304599006802994 -0.044007097013134 -0.169764599535377 -0.214815595773715 -0.220687270380167 -0.197514897417727 -0.200750044342511 -0.270739708011754 -0.12927147065519 -0.241619247631225 -0.0644748007462008 -0.242969069970446 seneciphylline -0.200996841494799 -0.228006122012913 0.124959827052477 -0.342239617349861 -0.259962466654181 -0.242424608961147 0.0314589943493174 -0.424209158705258 -0.245549979112318 -0.218548677122507 -0.201122285965014 -0.297066712737473 -0.210234086051571 -0.330074874578504 -0.198636418434674 -0.236719686273307 -0.305552140380048 -0.335210240728119 -0.408481020572716 -0.306917015713828 -0.370885483012144 canavanine -0.288984534072042 -0.490153217876307 0.354077246252578 -0.385391245050107 -0.40871204450264 -0.0919548199899782 -0.0572644676307395 -0.517686162892746 -0.394302169996044 -0.294582750227401 -0.196443766792905 -0.318742425746391 -0.540323355145746 -0.549238801428036 -0.544949514672843 -0.527540292757286 -0.165787047705699 -0.467938540521357 -0.361404974771775 -0.217688307030906 -0.366848120332066 diflorasone 0.10886177468932 -0.349994403039001 -0.0299986189822563 -0.229182342224915 -0.0727355014812841 -0.0300563567205666 -0.143866897103092 -0.309007686757343 -0.194233792948934 -0.220827563805013 -0.201777645131804 -0.172957488758162 -0.295423510403744 -0.326349547680359 -0.298041894754922 -0.295222425147519 -0.155567141434725 -0.305096296414347 -0.351972623791621 -0.252281917707332 -0.198279835515762 gramine 0.140186785723824 -0.185321696125037 -0.0156036178976079 -0.351896632830835 -0.131990118500079 -0.0449281468662955 0.269723659740817 -0.257720235799174 -0.163705984572626 -0.2471418923644 -0.0994903333910801 -0.0614488913146518 -0.12146308107211 -0.170176277083419 -0.242896551891809 -0.146514745096516 -0.266982198745688 -0.235978719552455 -0.242551562973066 -0.27320335614808 -0.114773559386796 protoveratrine A 0.0713466480046773 -0.368661576692145 0.0164288553112477 -0.321575992769825 -0.219947526377461 0.0749430621954101 0.217677954993417 -0.343830570728245 -0.350778584503708 -0.303865210756987 -0.25118573375159 -0.388036437039104 -0.34514248786317 -0.360049510808271 -0.317179003618495 -0.532086309701423 -0.205724494967725 -0.2117820443237 -0.592622302253928 -0.321805191230203 -0.256381149974694 emetine -0.452493059496096 -0.638760742495988 0.107114731702382 -0.310717626598124 -0.233793500137335 -0.362701885681779 -0.21386000906902 -0.578978430824939 0 -0.0372189770417186 -0.347241965439679 -0.446239888492498 -0.619186940902742 -0.47574654336752 -0.360037567004427 -0.4759013509357 0 -0.602780957660958 -0.326197457009845 -0.287151262295771 -0.483504543609843 trimethylcolchicinic acid -0.346764173492976 -0.38473240889336 0.524131218834338 -0.346708408249681 -0.324680600948342 -0.312433804611107 0.111561065479062 -0.415703994574824 -0.234908432840102 -0.403799828717878 -0.137690216723237 -0.258842562194021 -0.30441777024754 -0.314322668775344 -0.35669987291772 -0.309676571373326 -0.242417839265871 -0.483412969797361 -0.409408461661319 -0.284036752013265 -0.208865427701174 yohimbic acid 0.235863575145625 0.277325445003433 0 0.374499575754229 0.463765691817001 0 0.0823665285866219 0.290924937228823 0.421354467648774 0.00965941359507723 0.361384762682865 0.222630181871888 0.439826022096979 0.441050682665472 0.424584050075661 0.142590384098328 0.132230600147846 0.396255142471151 0.341957799852606 0.14248494387486 0.118890020667297 boldine 0.170604218940216 -0.0555945077303268 -0.2357935834919 -0.212765811082438 0.00932611588709541 0.257911028517041 0.0445459438407481 -0.0461828134307406 0.195151496975002 -0.0363395691774731 0.058920667629164 0.0156957113195207 -0.0127159056724173 -0.030442804649855 -0.0707009349603227 -0.0282321728790882 -0.127080120876325 -0.0584269329857134 -0.0275635101564762 -0.186550933746381 0.0663291223943737 harmaline 0.222875588230545 0.0334979249387454 0.201103865711695 -0.0745065858387953 0.0601211281845409 0.40776232274983 0.29135881203859 0.0921899455686956 -0.0156465207230798 -0.150255265248134 -0.00843238145281339 -0.0432115319342823 -0.0610115703266343 -0.0563172289577943 -0.137885739544807 -0.0350405559678004 -0.0176657908546188 0.0971004733506707 -0.143764988430614 -0.0543667265598748 0.0587649823740903 harman 0.212419161150188 -0.159137887811009 0.0940248582464801 -0.0844560012837419 -0.18465698509166 -0.203171130606232 0 -0.239527372875932 -0.0990118566704513 -0.165212877725903 0.198683809842766 -0.114040388061711 -0.175309685199744 -0.190921998335836 -0.175433096123835 -0.172492904745588 -0.0817760253648316 -0.22518525881913 -0.18217744875768 -0.135223410493439 -0.118539875298004 quinisocaine -0.201170252082841 -0.438364679420198 0.520197420796516 -0.368864856688478 -0.259488485488596 -0.286951748249241 -0.488946692407225 -0.575085673491795 -0.313508633657834 -0.620718426010153 -0.375990575061854 -0.497754095152977 -0.598459160658958 -0.487367974136323 -0.638328189378314 -0.344968126789233 -0.406019478796746 -0.623239077210446 -0.635879797823455 -0.358740524739171 -0.278946147605067 solanine 0 -0.520082963705134 0.363408732123635 -0.41537756854749 -0.319099436553316 -0.083568054985997 -0.260767640306902 -0.256058788341795 -0.384112840811288 -0.413127668936134 -0.363658050904366 -0.346409637736085 -0.463087724591145 -0.573594298495155 -0.429103262905793 -0.415032411327481 -0.304496150118437 -0.399931024609051 -0.466999408589032 -0.368291495986673 -0.475564389730962 sulmazole 0.608231086521969 0.304685626076051 -0.203987459622736 0.332593668918553 0.507347942779836 0.29014787839531 0.467785726766169 0.416729518944007 0.45727740042057 0.421716499290929 0.336425132237838 0.426631754925594 0.451600573720962 0.464867142350721 0.331471230792525 0.305522645067314 0.258497029591094 0.264557891246467 0.451538162677012 0.00159841017489197 0.357941818927504 glimepiride -0.351600407488848 -0.0892473795453913 0.0741276098621991 -0.170280601194026 -0.160357278447057 -0.241465319325102 -0.168003103329684 -0.165122109908578 -0.00907209886210106 0.0402075649427085 0.0809667788342316 -0.143056942198834 -0.168960441391462 -0.0841127742238486 -0.0828310291681732 -0.100151055298339 -0.142624377384254 -0.0779907600909663 -0.0430828546387837 0.0645075534631449 -0.0720530647129048 vitexin -0.073232169046761 0.000423085775757753 0.218822450944129 -0.0366203904193353 -0.0672401441101816 -0.00670945723368133 0.162704486870724 -0.0603971635201306 0.0376052062444842 -0.021304863482384 0.0444934204643715 -0.0507541831238475 -0.000571136158758978 0.0289593884632959 0.0305887072528152 0.0220114820337658 0.144849381514159 0.00339880977375201 -0.0164980151040177 0.0543254566075685 -0.0125037407275501 dydrogesterone -0.0638428628465581 -0.0216449035731642 0.101688334475634 -0.199851701091084 -0.126073287828517 -0.0546518276589177 -0.0970626108815111 -0.0153529640632744 0.1104667359266 -0.00963687962638826 -0.106760689861913 0.0632695196658825 -0.120555883408118 0.0149821160514418 -0.122634387134463 -0.17647457568822 -0.117708193286668 0.0393278493931294 -0.309957015915237 -0.162790078945276 -0.00707618747224895 hydroxyachillin -0.0528496932743692 -0.0623479714766639 0.104428609337415 0.0152009689393315 -0.210817329616677 0.069057221331926 0.027689385042037 -0.0810281568817187 0.0264176967856715 0.0296000008158683 0.119519452212974 0.0749501599540422 -0.0815204285620355 -0.124586602220153 -0.0443523851883245 0.0842625876383789 0.162821390975959 0.0908029038844634 -0.0481579278702572 0.138238642849185 -0.0455102705696393 trihexyphenidyl 0.169034099412414 0.49391498215111 -0.321795425773824 0.300022331757131 0.611819127991222 0.178315017624414 0 0.37686088432811 0.489975491389336 0.352579954786097 0.154371605576159 0.357006133262057 0.542883617155893 0.545480425131066 0.486732352501566 0.510815607459204 0.0730000541421464 0.332751011251185 0.368219014896112 -0.0176562833645696 0.394489796404928 sulfabenzamide 0 -0.256936980277145 0.11258307421822 -0.227705751416921 -0.210941652498402 0 0.0307453257318381 -0.21536225859979 0.0976577164865914 -0.159562425702719 -0.0296670441886095 -0.0688127424363219 -0.1689624075343 -0.256822002377984 -0.073166766293188 -0.219393993693212 0.0341863561752826 -0.163519751422507 -0.167652238576634 -0.128414868456592 -0.138668552443291 Prestwick-642 0.494199833962455 0.501874464611406 -0.123880710861403 0.564848697593676 0.372656181564605 0.142407614493975 0 0.261785331191561 0.376413950763137 0.484063250604476 0.419094582615419 0.407949501113008 0.435936741665678 0.459932691749592 0.424851365448178 0.439101396346695 0.44807226210174 0.467594251747174 0.366129712984185 0.189664186565672 0.426014199013314 picrotoxinin -0.136398261218759 -0.331711107487955 0.214826113914916 -0.204400056801047 -0.312903366126169 -0.303944494263469 -0.00445236800130433 -0.311376012763632 -0.287739490338232 -0.367162142688359 -0.262233164989579 -0.360774430160868 -0.376811951420317 -0.369921550507276 -0.337576926737528 -0.328174252888752 -0.401042171265321 -0.252514539283027 -0.275162092720986 -0.0245698152828733 -0.236061280095555 gelsemine 0.248643747518641 0.12759858729619 -0.126916160229538 0.000817249380374085 0.17354995505153 0.33682107508847 0.154027398887101 0.206563910133341 -0.0404183510458019 0.147682114511391 0.126834414100869 0.175135626975459 0.192944263254006 0.205780874279918 0.211692520471208 0.163784670145967 0.0120707784050045 0.115803177987779 0.052129771733813 -0.0557517436320817 0.251848381935667 canadine 0.127251420434166 0.599740873670551 -0.313058865642376 0.436997144448536 0.594272089344034 0.312597910670425 0.303990759187817 0.48603297322993 0.534362464207277 0.605510810351336 0.339835306301355 0.557817927557264 0.473198712899718 0.535892591408778 0.477876466216586 0.487409154667455 0.340870838417362 0.467259619087275 0.563276922232675 0.169838195257705 0.370344734921934 Prestwick-682 -0.291777474486988 0.0804997780300445 -0.0327721811015529 0.130967219974063 0.157704097112095 -0.0844907146061334 0.134208848323048 0.0566387453330975 0.147567652300329 0.38180230646989 0.0826953521345053 0.187801169733131 0.12126492318334 0.107957476864864 0.0558461483111189 0.122931462613139 0.263958816766529 0.119520071412207 0.102378727324741 0.0806566693075551 0.075692655343599 Prestwick-692 0.151981554274138 0.705264722452823 -0.0266944954374974 0.64510757896629 0.675892310324312 0.328844870694573 0 0.693770732700516 0.657484208947167 0.712977473200576 0.495826779207531 0.682271059925088 0.718694109532087 0.696571538207353 0.72337311484448 0.687138966185189 0.604184537774215 0.685154309088327 0.725663756136114 0.161282236747389 0.44838798932539 succinylsulfathiazole -0.256196143835519 -0.0299206400230208 0.223660581893329 0.0606181094935799 -0.0841338033292943 -0.246067111627368 -0.264023587064118 -0.018266113482104 -0.0990745458858274 -0.0379222557367912 -0.05211564308066 -0.0844992419207152 -0.111367503323282 -0.0463748647783735 -0.112304502780214 -0.0558806683400175 -0.0493133076185439 0.00325021752491575 -0.00701345558466063 0.0530283215071813 -0.180699972825233 benzocaine 0.0851885915611457 0.53710644708327 -0.241760729570889 0.504310329069914 0.38349424138941 -0.106690450907643 -0.0018994297530274 0.39106264073614 0.447083489938131 0.516041978396544 0.384773863395452 0.306582062189618 0.448006894258608 0.553921162785549 0.41275753246385 0.522859490591062 0.611208862992711 0.594490100647632 0.576550281929751 0.155489202382937 0.49198052748584 flunisolide -0.26442238114093 -0.558066719213026 0.12245286156358 -0.391565802741921 -0.362933717068063 -0.117174554510646 0.0383168030048257 -0.466901160152916 -0.510638183751077 -0.562484048103221 -0.29384994029818 -0.404081876073454 -0.530726803615952 -0.582543414710603 -0.551687696635725 -0.492404225879101 -0.226418416162702 -0.529655520876693 -0.505884431287905 -0.233964098123885 -0.248399075062681 mepenzolate bromide -0.158900473175993 -0.437543049653908 0.0880112991567871 -0.29559975035225 -0.370258146688283 0.00833933201412127 0.00102119654111786 -0.41306451257082 -0.395659888099995 -0.497293728599095 -0.277369234563839 -0.454848054995759 -0.412438147334325 -0.446177739654873 -0.411627374056299 -0.380616278762381 -0.184738290355068 -0.538215101783326 -0.29937404182327 -0.230985035242897 -0.168874885729903 solasodine 0.0228291879200087 -0.443895648414364 0.177991761912118 -0.38487601812271 -0.357921630403078 -0.160311712258653 -0.0164926845962079 -0.298511023890383 -0.275658807805747 -0.367627877600715 -0.231624096950391 -0.390468997764585 -0.36943662083943 -0.459503001102809 -0.478453012149644 -0.304222442310333 -0.204653180582672 -0.406989068659688 -0.435204490287047 -0.208271670787648 -0.263397294975091 eldeline -0.0258984741743797 -0.431802479277007 0.151277243109646 -0.246135030001882 -0.510197886311293 -0.244327364089331 -0.103503370586178 -0.389476884970522 -0.173741255476559 -0.285834781973773 -0.251538414849754 -0.318203789522128 -0.38532297256589 -0.410268028739302 -0.456143988473095 -0.348058404993705 -0.0519524462155928 -0.292219670904185 -0.300436686957777 -0.0243659297404076 -0.175797184531395 pempidine -0.158814612532 -0.487148476873688 0.10557399050133 -0.132185050671627 -0.469121615210018 0.203359702843086 -0.341675560315154 -0.491078798407609 -0.319118897437952 -0.350918813660913 -0.252424877114397 -0.394065710330731 -0.434595977061086 -0.535629712049016 -0.407906645223425 -0.405601317962768 -0.21652733994372 -0.410261771992141 -0.270801898290677 -0.268756990132648 -0.241809543606102 promazine -0.113190473308773 -0.580680122336862 0.0877718145474154 -0.499868929436678 -0.52625368598557 -0.260921317248161 -0.490116171072986 -0.574403999422094 -0.530739904568643 -0.643322093215076 -0.416572927161145 -0.513038521329371 -0.627446433696849 -0.618086970534708 -0.624253346109653 -0.507232613693524 -0.452966584509509 -0.553004229103029 -0.599369379322902 -0.493538631901874 -0.34528780367333 famprofazone -0.00707858869729032 -0.410823267615821 0.353928998607847 -0.460351968825129 -0.436598938856154 -0.106273315916223 -0.188277906960775 -0.446552698702782 -0.538245966506762 -0.57708339467747 -0.496044716170486 -0.491164577226243 -0.508722703921058 -0.484859456445648 -0.467827280052619 -0.408074847070758 -0.307341797544909 -0.364849809086152 -0.494311187830825 -0.250690238344018 -0.440623658867044 metamizole sodium 0.101788590597397 -0.445069333811875 0.153862031424367 -0.404452051076896 -0.464257695699044 -0.0915604459129425 0.031984778098844 -0.523926396407612 -0.416512344189067 -0.436935818563886 -0.245138999613685 -0.380921637134587 -0.47255798524303 -0.581451988872114 -0.541722133285082 -0.420590836682198 -0.246308402081389 -0.315790336938564 -0.363073190623045 0.00189803131197153 -0.393372336248375 citiolone -0.0444320209350129 -0.399225729605313 0.234165938954688 -0.324098530696396 -0.357368352696863 -0.315806675684667 -0.190416324423298 -0.477480389624299 -0.217054967593675 -0.428339122076186 -0.229446024690333 -0.312409101626621 -0.41798533998731 -0.447770542878819 -0.446782747863763 -0.325692422717961 -0.14283092871295 -0.316429800663862 -0.416120604977318 -0.264345032280443 -0.204933942004074 benfotiamine -0.107289466697645 -0.407403548342968 0.252919898140356 -0.265335293995006 -0.372243632225612 0.131076908041759 -0.11934339080019 -0.404713729641019 -0.309572402293007 -0.372151226020211 -0.220826066305984 -0.305141075410099 -0.404423670118699 -0.438623154201278 -0.412127694973816 -0.375948118170246 -0.2929040412858 -0.432326436345497 -0.353872407373166 -0.0706507376778688 -0.336636780971723 Prestwick-664 0.00478393519035044 -0.536305240005885 0.23430193341281 -0.39597488574911 -0.304337357953076 -0.00487845777887144 -0.150141411688932 -0.383321581781033 -0.448581606265665 -0.541665831154238 -0.282860733466806 -0.473481941090447 -0.51777494009661 -0.572230542080512 -0.510305594889127 -0.446977152801716 -0.379840377550446 -0.498752053749746 -0.566906124113943 -0.299797893689041 -0.316443793262334 Prestwick-674 -0.209466082734652 -0.538263668238516 0.215143932931722 -0.416617029299046 -0.420781134517897 -0.16296940857494 -0.206138437619929 -0.508979797885748 -0.522292694498624 -0.516914181236622 -0.353954888771908 -0.462095830665104 -0.454508679941007 -0.547559993955295 -0.558851028686695 -0.463257576877853 -0.296371497424661 -0.461185764991713 -0.469032747020234 -0.232804994753197 -0.278152514619316 heliotrine 0.133627442565432 -0.409517983082463 0.0696325998162086 -0.477176672069239 -0.283677971687057 -0.0050150192563848 0.0983415709099088 -0.382332801779311 -0.307989250625797 -0.488293331558861 -0.346885139251464 -0.253473175182202 -0.474646870458622 -0.5000318957621 -0.407477714861301 -0.314459344399516 -0.304854205741627 -0.413944685545995 -0.592319077516507 -0.1526331514825 -0.170438340038961 sulfamerazine 0.0357023573207981 -0.136510427545037 0.107238712343163 -0.123847109206638 -0.285994333097349 -0.0738128105883444 0.1292294209376 -0.244961525541522 -0.268405189316472 -0.133386684808343 -0.209208137661025 -0.102773657354076 -0.220356353949494 -0.0514239320190823 -0.19538146994191 -0.0325994988872676 -0.0301279667838262 -0.0228885963893764 -0.0898797926624134 -0.0316953546557251 -0.255763117278905 bromopride -0.133283463965582 -0.235321298650548 -0.248825032011012 -0.168454082124817 -0.364832809845849 -0.070826452434934 -0.0642467814445964 -0.235404993270297 -0.219395035465595 -0.256244219248285 -0.188427545334052 -0.266145340515865 -0.296528610640946 -0.25600957886755 -0.248633655225399 -0.232991709014543 -0.27282202942088 -0.208014987506801 -0.29823702372495 -0.0780811968199712 -0.131560640734086 isosorbide 0.0690990913006505 0.144448366855987 -0.155310181394194 -0.0615646487145153 0.220650589707861 0.236051954978766 0.12917718681556 0.17331253872756 0.00923448601657921 -0.0494754004016504 0.00877626473604767 0.0939649522603476 0.192546888890454 0.172916610051415 0.210577667556123 0.198313734994858 -0.132266590287352 0.135950279004276 0.112483164484618 -0.091120260415983 -0.0404550961214535 fludroxycortide -0.0597059162614 -0.557944770990906 0.207089284463947 -0.481650602475766 -0.367261776924422 0.104440406834617 -0.141295881899576 -0.398986738880304 -0.398213173405929 -0.390098078193339 -0.274007064506629 -0.254372411123847 -0.426485853436665 -0.551985899556052 -0.540518769987559 -0.497594266504908 -0.443000443853587 -0.494888426828316 -0.54753274891004 -0.410890612868005 -0.339116846832889 halcinonide -0.0951849773062371 -0.558110498708208 0.0253333907757152 -0.432314723710953 -0.387036617901136 -0.199225967135653 -0.269780984513844 -0.552041400208738 -0.521988040552493 -0.459756718998687 -0.311733998490214 -0.403985225980203 -0.547478138145245 -0.573953524716641 -0.620376446521032 -0.393833300921816 -0.429772094234653 -0.557867028326364 -0.588971369473622 -0.487312838074245 -0.587325542769481 Prestwick-665 -0.155531325433136 -0.566687286634377 -0.0156668174799449 -0.556673161843807 -0.494917431610238 -0.221564648743081 0 -0.493851083735604 -0.556501962434809 -0.528762264964352 -0.373403802844237 -0.457341444366332 -0.550833168010568 -0.575167970809467 -0.557872548318559 -0.531673413278072 -0.413108233457609 -0.499015296503117 -0.69208006060792 -0.0869606129346222 -0.572936156348093 Prestwick-675 0.336409853365492 0.341064927463449 -0.19999689695676 0.228524331944552 0.224405351495526 0.362379636705687 0.463406064988727 0.346444298771135 0.280902909941649 0.187454260110864 0.226786849216021 0.576026002696619 0.298294301431045 0.214612112133033 0.278244653960308 0.24234046515088 0.385513896804975 0.265886616406404 0.0201289818385109 0.551479575090636 0.277190315002432 Prestwick-685 -0.349538309990403 -0.544278430861833 0.243054813692968 -0.47843988329177 -0.505769731388115 -0.271191244841113 -0.229171945721681 -0.591838794135239 -0.47389647509866 -0.435210014707177 -0.464820009017749 -0.49738617523936 -0.56725143385872 -0.552534730882439 -0.585787132778374 -0.522274843398862 -0.419181784990796 -0.513924342369266 -0.560992145792376 -0.256108159430366 -0.599869796779482 acacetin 0.182698461156699 -0.101707292798191 0.306759672490463 -0.0223056413611319 -0.19370156350984 -0.0967250140428206 0 -0.132150692187418 -0.16966189754004 -0.0284779158657721 -0.284985267934261 -0.0195315790033234 -0.117165874687895 -0.208327411863864 -0.314587308111796 -0.0214233177663822 0.108844474039422 0.0681995012988747 -0.344597823017924 0 -0.378974719316872 methylbenzethonium chloride -0.303013839115595 -0.486403274873008 0.275042123909443 -0.38423753676875 -0.365370451830355 -0.10533566840299 -0.415335411160828 -0.416327991439028 -0.594057553957336 -0.590113520058488 -0.442955437692103 -0.437181624782552 -0.420402610050002 -0.505230433114415 -0.549235785870356 -0.467876594075131 -0.434974263010612 -0.544366771209411 -0.566157089439687 -0.459542919374506 -0.27239312377943 sulfachlorpyridazine -0.0492685071637779 -0.281444369371126 0.112780200938257 -0.219534100863232 -0.128559432672492 0.234424997254099 0 -0.232187074347849 -0.234016288786632 -0.289034438799947 -0.177628541992361 -0.26367524945906 -0.304161821183234 -0.34866204106934 -0.228813762848444 -0.281028444283963 -0.146026421955668 -0.165992184377822 -0.397496244951858 -0.145084952858589 -0.163496254695627 helveticoside -0.364415833568692 -0.320091740609738 0.128700722537755 -0.14105111740367 -0.26089315269931 -0.590502513456421 -0.197875433855507 -0.0356487112241641 0.0863238024510436 -0.0980024141212872 -0.118187290705275 -0.133905549696309 -0.317686494368146 -0.251301133288959 -0.092719662753786 -0.151341126862361 -0.172908385721799 -0.181422309747621 -0.162757299105261 -0.0427893478922595 -0.00296585390027658 lanatoside C -0.447307946509271 -0.383107319341395 0.145734678930981 -0.164993980794039 -0.279744587493368 -0.632813557710322 -0.277704887442181 -0.180830298579077 -0.258056233890447 -0.193324349401275 -0.241008314934108 -0.22125214488521 -0.341088522079826 -0.342151382800829 -0.0717590929653184 -0.210050160753298 0.00641312757971109 -0.279287175688857 -0.0855579318295017 -0.092882563874934 0.11629419781622 beta-escin -0.548108184715446 -0.572787545556829 0.0497325321070378 -0.489736289253293 -0.539210904268569 -0.414697225109504 -0.46627130046595 -0.519953959974577 -0.475337006631518 -0.372543423051918 -0.41534984933405 -0.49695092956288 -0.56151923613777 -0.625119578164803 -0.56384865598875 -0.510156999918946 -0.42111701986214 -0.5498823283662 -0.469294394648441 -0.209176769518971 -0.384077224371774 lycorine 0.00888061250783392 -0.169164847954593 -0.171838572184254 0.0211220559302326 0.374815403097852 -0.109300625363652 0.46095372208563 0.347311979642476 0.317651711178236 0.188845861857661 0.0361267730850123 0.434392418563035 0.217847364613938 -0.191600064072277 0.101215624723032 0.189350829286193 0.0804496080276274 0.0122489649204553 0.209572300992765 0.380502127199687 0.0128609269508036 ethotoin -0.0799685184507592 -0.637192253955925 0.0846252799688564 -0.470822603139404 -0.621762381272106 -0.00341850206314484 -0.195304463915756 -0.600929203303491 -0.531369188409937 -0.550428537123393 -0.359274086668093 -0.560532849563846 -0.630406649447194 -0.664343502437308 -0.553061093969095 -0.533694626362015 -0.420773988396984 -0.551553866906276 -0.568076371559647 -0.414241886420773 -0.416255942400019 chlorcyclizine -0.310127551252294 -0.174174429574321 0.218344942670682 -0.16180526775978 -0.163971034522767 -0.0245291094239787 -0.327432046643236 -0.251350758470776 -0.306125766142637 -0.258735230198589 -0.354157056698364 -0.260141000476786 -0.234259190947597 -0.240535338764612 -0.313577288445317 -0.156086057774548 -0.197821240712487 -0.26581606216573 -0.156198341873898 -0.179811697365728 -0.0171613572544105 pramocaine 0.187473336659513 -0.138628068032885 -0.0501165534505363 -0.145444471607429 -0.0906950541435415 0.00382299044508587 0.0295716793638077 -0.0246790872716568 0.0677258749974013 -0.229423175674546 -0.0152005899982724 -0.255602705460256 0.00409833793604304 -0.0893408165332863 -0.157921318412938 -0.0628463153081551 0.0217771517779583 -0.0557781778349421 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0.272073625412536 0.0694106301830317 0.364682063746341 0.051840482074968 0.321671001505125 0.231115606076658 0.183902358202061 0.168160890791557 0.189358877914467 0.0890467959802038 0.181893207845338 0.0462779580016657 -0.0767976045903689 0.11524595947262 gossypol -0.231118163373751 -0.152766027323499 0.0785263127475343 -0.120144662207111 -0.109907307876925 -0.0437417906843608 -0.338889666321027 -0.17328969995583 -0.429366464784962 -0.271542102222677 -0.348324323561656 -0.208049259735244 -0.252207922623935 -0.30380582616951 -0.407171002157781 -0.144124745846005 -0.307007646675086 -0.299631659190934 -0.161063495839797 -0.336450427283613 -0.279378905130523 karakoline 0.0171231265722945 0.31907086770056 -0.178314282464561 0.0779427849611924 0.255636489943051 -0.184830167048928 -0.0946093979063574 0.20560984029141 0.317262754708773 0.320794572595437 -0.00247359214434033 0.262968182213098 0.213700817016069 0.380298564368491 0.35061493805115 0.27081551692367 0.0648968713002342 0.253553597535406 0.26724257053417 0.0644738998293494 0.0826328389446472 etiocholanolone 0.127073535194693 0.557042795545814 -0.150728633265007 0.469957471629688 0.47511280436154 0.0695491182176878 0.0965317490641699 0.545240352708744 0.463863831840966 0.603235408185235 0.316144131095698 0.424275433185386 0.552809055137863 0.615380126000287 0.527725674925061 0.488854128190792 0.279956495829318 0.499063271744686 0.596853047067163 0.0965268000327926 0.436595013962707 diphenylpyraline 0 0.300139085106344 -0.0122111363626256 0.292001533729097 0.212410185706864 0.140263463371673 0.0671005229999692 0.30789451748039 0.278699643170487 0.245649672875832 0.0663310816160747 0.303512817072361 0.310081421609617 0.241844682802705 0.246522944268186 0.255600105650817 -0.0061361347471682 0.273423777784722 0.227386808122666 -0.0825068900910939 0.198305532320714 finasteride 0.0931782150891166 0.546809340099238 -0.193416901998761 0.356749269935156 0.555085902614499 0.400303828248371 -0.0108983616218203 0.496972204231169 0.37164839338395 0.580927073122553 0.307748663983083 0.449014166762982 0.437832698736883 0.472039355233696 0.477740066054376 0.378624026846641 0.234525500343218 0.428854937033357 0.490061886369121 0.12950376524787 0.3090021946639 betonicine 0.0616255908967336 0.211571792440355 0.150405361997591 0.126719961284642 0.281091763418861 0.0700425181474865 0.198667021757286 0.223430610783677 -0.0223761028160299 0.192587465872656 0.0621175425416954 0.248834019120357 0.236884597211004 0.160793651280618 0.152698921802124 0.163482243345084 0.14624094059439 0.208684917766264 0.203233375731026 -0.0971624697842041 0.232995887140582 tiapride -0.0514562099902262 -0.31588455405399 -0.125989174355413 -0.228641797673411 -0.154102189036066 0.0451126133578439 0.122753451294867 -0.199884649147154 -0.136616694743801 -0.151907170141301 -0.144867848193034 -0.116265075433154 -0.157051651072552 -0.192506662393373 -0.326030222260053 -0.153109176804481 -0.00368515527871146 -0.246632810120155 -0.328400658438567 0 -0.238992720043755 griseofulvin -0.258423542138923 -0.14355856149977 0.0585711411158815 -0.195600177878876 -0.0672276705699328 0 0.111016568000602 -0.240288064422936 -0.0497008698914468 -0.150135651974145 -0.155467546753172 -0.111531448163454 -0.0855556381775832 -0.167464118337859 -0.186188552916864 -0.249856284590245 -0.153525264606309 -0.238199975840224 -0.168527359348031 -0.161253117318928 -0.0612616861478215 dilazep -0.339973269739285 -0.366769512727193 -0.31798515723015 -0.446993217383226 -0.376766342284886 -0.125719971395905 -0.0146663806762465 -0.453306515397333 -0.0888666239730313 -0.331095682786795 -0.214381818117446 -0.320307728208239 -0.28866899559813 -0.407792741643985 -0.389209792611823 -0.230949477382053 -0.211280269251971 -0.304797232917168 -0.428859432909542 -0.147894386377128 -0.491365934059813 riluzole -0.0206731932962459 -0.0759479737112068 -0.0122646490873375 0.00626982598877033 -0.14418615081287 -0.269722328515079 0.173764543782855 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-0.179513602980665 -0.318515163157481 -0.162616959411233 -0.112694135693628 metaraminol 0 -0.325677672062501 0.336912823319425 -0.26181301439145 -0.282609935443802 -0.300092362037459 -0.372832811055036 -0.265001656521013 -0.218289857986197 -0.221933729398131 -0.213639064224195 -0.254704154163597 -0.311142581833192 -0.298375086596229 -0.298913808797236 -0.287844164967112 -0.210834442889784 -0.278741812540395 -0.350158052455377 -0.273311894419766 -0.280662542814507 kawain -0.22498157603953 -0.331298918053029 0.411364031735053 -0.249216486136275 -0.316760724894597 -0.147085494401776 -0.268396443379346 -0.359785883756623 -0.184941555414454 -0.267597362437233 -0.171680229700477 -0.241773035430308 -0.323409255182276 -0.288133785488216 -0.350932186682469 -0.304595993385902 -0.219627832939686 -0.335867858943348 -0.475748877272424 -0.306088780215766 -0.285777053598555 mebendazole -0.6669719992811 -0.609924309360404 0.664316206306489 -0.597647284937937 -0.596430106288025 -0.836528149354248 -0.512835501758063 -0.494085691652477 0.0486187668278908 -0.385782258162827 -0.438884259591405 -0.424939951943592 -0.612869831448788 -0.612545505998158 -0.506892509208096 -0.627049319475102 -0.592395341990783 -0.590279298621022 -0.65920701700081 -0.404258044082882 -0.562195001732559 clemizole -0.244200628539097 -0.562066038093533 0.180306058061745 -0.468241666692606 -0.517294663640063 -0.305185613724317 -0.299189803742156 -0.590884009594723 -0.574126525558881 -0.548164152868703 -0.392397640585638 -0.527355828856569 -0.498948289931769 -0.616985055470688 -0.735696049523818 -0.550154035815345 -0.401031325342411 -0.535554255726195 -0.444074144315168 -0.31565566083206 -0.501948150397848 ofloxacin -0.120398594858954 -0.19024146395232 -0.260187394816016 -0.379691548377372 -0.0986681002820149 -0.11464185502666 0.244675201079236 -0.129717451071229 -0.0851456544918849 -0.103677381932074 0.139585595073639 -0.0310648738409825 -0.097252515960172 -0.282691893167937 -0.228380628568654 -0.123438238263332 -0.00354981750667619 -0.183366299781692 -0.309102599021351 0 -0.255810995999007 nitrofurantoin -0.250923277551117 -0.445760689043726 0.285455531148905 -0.384173085291702 -0.257011603611577 0 -0.215634425738733 -0.523052868927746 -0.356851072393328 -0.439461323767405 -0.367358556668083 -0.424355893263627 -0.419575589758128 -0.384513414519789 -0.587556004172525 -0.360770516723492 -0.273447759287013 -0.364949139356779 -0.634847500456992 -0.110715525276249 -0.358353309155232 mephenesin -0.328706867284895 -0.330036160740562 0.161695392910045 -0.113183014182735 -0.28962355748522 -0.256750198435177 0 -0.340216397946784 -0.338959622732709 -0.266931408929388 -0.298522601896199 -0.235490765624003 -0.362288268110918 -0.390982080161974 -0.377643762999691 -0.251179640383065 -0.12938110540657 -0.272402517317987 -0.201363035681081 -0.177990161902056 -0.433700703802025 pentolonium -0.151959525381235 -0.182336801086735 0.402659788077796 -0.339490725137829 -0.19566504788314 -0.341965687754985 0.0992056220073451 -0.179674501919224 -0.206960490821451 -0.167554815281605 -0.15530016407121 -0.109286561427007 -0.184828796109484 -0.224654138723779 -0.209056465319681 -0.169841050768097 0.0125577251422114 -0.142684107714484 -0.300404800568141 -0.219780885261197 -0.146640855465547 salbutamol -0.390075074712589 -0.346250936748432 0.405170933862773 -0.325435829511367 -0.355262921421689 -0.177778823328107 -0.111538212347306 -0.230591230128089 -0.204198986699662 -0.257388952860783 -0.21562347479007 -0.175280974755137 -0.333826583436919 -0.266580640732032 -0.348758756096589 -0.469939817288681 -0.320643570054564 -0.4018657856318 -0.583169316982307 -0.260286014891691 -0.211421676329333 trimethoprim -0.119302594096111 0.115680974447006 0.0882888243490741 0.0409185943624493 -0.10999573375857 -0.0588185578649123 -0.0182234065269105 -0.0701402248827509 -0.038662977098412 -0.0537571949352462 0.0962802677044337 0.044637494330142 0.0639285269273596 0.052544131266419 0.0452976585138383 0.127177023271025 0.034899472726274 -0.0681595564289899 -0.138726241979955 0.0136336147714797 -0.241371797124531 fenbufen -0.296671952990938 -0.184202721213948 0.141842092515824 -0.0807015650042879 -0.230808761517009 -0.0978649753442459 -0.0120499669700554 -0.230830821175605 -0.0857508570390443 -0.0564240400206328 -0.16406751960104 -0.129162927492495 -0.173993504137991 -0.248333372788649 -0.222318558869767 -0.175653280463299 0.0578703730889457 -0.212799361726232 -0.287780115821254 0.0307083173021337 -0.0285814271947104 tropicamide -0.258664394838002 -0.387530913785215 0.228568937923702 -0.316791446488904 -0.386998241027762 -0.199188941057857 -0.320377643906198 -0.406846098672967 -0.130833362880052 -0.334571310844983 -0.204073463219648 -0.412436872601421 -0.405097030704412 -0.352319149063489 -0.329542448243768 -0.43485785246897 -0.193632481236613 -0.376941616882415 -0.351950606957669 -0.205865383902376 -0.154674760734831 lomefloxacin -0.147772352614885 -0.296138839436795 0.124400196361717 -0.144074745685366 -0.324107650589944 -0.255015128616814 -0.199485872335702 -0.26444345381523 -0.0872926015449404 -0.120832168466034 -0.109883904892166 -0.09804238231915 -0.243336995899915 -0.225280298125827 -0.245270389682429 -0.211483184130523 0.152854468495736 -0.252279828892694 -0.292327141406142 -0.0701305136055022 -0.0310840983977725 hydralazine -0.183187374416505 -0.247783307003093 0.122630134912237 -0.0769450612717555 -0.335554734600209 0.0522014810294328 -0.124026564063379 -0.344280566305408 -0.112182972531274 -0.0895779300196929 -0.0581194866010968 -0.000241304134839332 -0.189797767570116 -0.347596604053472 -0.274005171731387 -0.212068603930494 -0.161209150517339 -0.366532237712509 -0.153845123276706 -0.136201981367592 -0.228618586229128 6-benzylaminopurine -0.249301224259375 -0.197740047788972 -0.00472294481974138 -0.228170121340718 -0.199403133664639 0 -0.11154583045291 -0.189957585166914 -0.148612152450879 -0.167515492433991 -0.28157938371661 -0.164854490839115 -0.200976499830164 -0.206820187626576 -0.246707937942121 -0.197517054910078 -0.249180179626174 -0.167989185944713 -0.214760804559642 -0.324544825821492 -0.131650442720802 prilocaine -0.0323957340629494 -0.0417163885340404 0.0379656412365186 -0.189413687764496 -0.16715039965628 -0.112704103002391 0.175404193198003 -0.0723903290550733 -0.149793954520982 -0.14178680975377 0.0488094711818819 -0.108648296013811 -0.0247174057504816 -0.0880781815718799 -0.0968911855649428 -0.153199822334952 0.0447021812433252 -0.244051779852719 -0.144288880995122 0.213162112000518 -0.180756915813376 metoclopramide -0.112495134596863 -0.206950191218489 -0.0918543707455204 -0.0989533955295324 -0.185443848853589 -0.0729692117436833 -0.14809020708313 -0.163427076072704 -0.200575339819565 -0.222229975040869 -0.0737862564498248 -0.136767145155736 -0.18419434911387 -0.189672724134589 -0.266087300846168 -0.205039047072413 -0.151862015660683 -0.309049470009799 -0.174652068928069 -0.226567442993734 -0.243079746248994 ketoprofen -0.145809012186494 -0.297508613746042 0.0385992460455797 -0.297799921868381 -0.235925556307261 -0.225822107911396 -0.080386558984873 -0.370072212845135 -0.394656700077289 -0.375093343954111 -0.1502448205733 -0.211875159465544 -0.330085526479675 -0.317135941970684 -0.425868915869815 -0.209139355037503 -0.122579408167105 -0.308565999191001 -0.250687137026443 -0.0796850108867776 -0.249635972157173 nefopam 0.0104745480766285 0.189386425107259 0.0239082096560339 0.0297248917851032 0.0459356363048487 0.174962622971201 -0.153019071386715 0.217287014630062 0.234776764655502 -0.149478044899721 0.172962490784982 0.0351695866852183 -0.0463923933084815 -0.0506868809641583 -0.120172717843934 0.0376881737566477 0.0668851684697085 -0.0788863121757633 0.0545475582104927 -0.177282821959455 0.012873920021458 orphenadrine -0.0873533334047514 -0.0715249124732512 0.191341911073182 -0.0558797033889795 0.0159816823045265 -0.126695803181596 -0.202633069500418 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0.132138074368413 0.253593196833073 0.0207559174123713 0.243794170543716 0.0390303475353233 0.184855078278213 0.236403193860963 0.177501216198618 0.241065588715306 0.297007086285101 0.230269492844299 0.235719483684657 0.257338489644633 0.0545308184444483 -0.107471422078532 vincamine 0.0692758453566866 0.337936724123493 -0.131444709138825 0.115773869555055 0.354357038126946 0.283731442209804 0.0450571389197718 0.362009579758918 0.160283370126994 0.298910992737025 0.13950046331465 0.25637528062572 0.37483338803593 0.29276858277115 0.454465655559323 0.316925801268792 0.199526183411907 0.428058069675465 0.406162917220761 0.0126903256900232 0.209410073870495 dantrolene -0.136740064834713 0.211676903332098 -0.0760094200537102 0.105371043316051 0.164554495695615 0.266213158699553 -0.0537037975530711 0.185589155776322 0.174910868054826 0.199541510912748 0.00625636753075008 0.130569816779528 0.184215117704659 0.187118245675966 0.185476116901744 0.184327480684531 0.151746855900492 0.128022581212497 0.13344914431685 0.00364531386093806 -0.0898135713359972 flutamide -0.0482803846468046 -0.359770266322858 0.203076803801149 -0.317174806275842 -0.00514099810551999 0.116841506912579 0.0949864940932252 -0.416396768331585 -0.288962390610573 -0.193406830846765 -0.164537496099053 -0.00568187900906141 -0.199879234810005 -0.268520737249217 -0.536246855900087 -0.171066879575917 -0.0831677248078436 -0.0958102227940602 -0.456090252266545 -0.0649486045506769 -0.0687443157163297 fenbendazole -0.301035213263146 -0.221309809200153 0.451809744739707 -0.21355962344045 -0.191203279664259 -0.307201945385888 0 -0.20687338686067 -0.0909085287831092 -0.118430583541233 -0.238319426992492 -0.10896677697518 -0.251075953646086 -0.152331992155139 -0.0438607403361517 -0.240079836169732 -0.112278026615979 -0.0348367771846762 -0.0915211085000122 -0.282873068047834 -0.361728304275164 proglumide -0.118472908874598 -0.163239403261777 0.366563618958614 -0.299727097537492 -0.225068957833692 0.0899111910400869 0 -0.34047580498542 -0.181047219398914 0.013872575818469 -0.145476601673747 0.00648743671722617 -0.141563670421986 -0.230109229025175 -0.243406383134509 -0.115344816466164 0.0139748875138041 -0.176473934752152 -0.387472056121881 -0.0745290656346141 -0.15867651603719 lisinopril 0 -0.652051926268997 0 -0.580831325306429 -0.392582602648687 0 -0.294501361459748 -0.615685742709614 -0.419797853315151 -0.666356916293929 -0.317853388873957 -0.573238382047946 -0.446455339912419 -0.5022580296568 -0.665364694392961 -0.679559745704082 -0.369427082878676 -0.677258686953298 -0.668911851481644 -0.342809969169268 -0.353265978912735 ifenprodil -0.226226826027983 -0.673161084804307 0.140318152762486 -0.5808273076864 -0.667645849155505 -0.343420606827286 -0.563601000815197 -0.698896727876953 -0.57481199275817 -0.676819118832522 -0.490332500600135 -0.615150921322171 -0.696258376002267 -0.709283215590955 -0.642905421894752 -0.711239404967896 -0.54944043927047 -0.654935376259432 -0.680378948450106 -0.475870779290201 -0.52508311127152 flavoxate -0.193863075460655 -0.349836199409475 0.111749825702399 -0.317219670114028 -0.317109020559442 0.178500771332898 -0.298150731894392 -0.361387595454441 -0.186919154547014 -0.358686504788293 -0.264618024076586 -0.263298990253962 -0.349198629949644 -0.496562353772783 -0.396747924473294 -0.503497459618922 -0.430785936182062 -0.337530165659726 -0.405404875237563 -0.402543714938301 -0.319039080284116 difenidol -0.151406993250127 -0.657237194534295 0.0117629603248735 -0.645416758197443 -0.668740901143824 0 -0.454560592305349 -0.665923675162847 -0.486390884051552 -0.339129132901252 -0.429409671273667 -0.412733629071674 -0.665475885430597 -0.679739053213603 -0.627275947840843 -0.648521652696589 -0.401250194849105 -0.656504990453405 -0.73218487857606 -0.220335110250195 -0.514966764009142 triprolidine 0.232700405922539 -0.0447941023062176 0.160584063862659 -0.113532097287087 -0.0142973196861785 0.0105244573908884 0.0988628668603962 -0.164072550908286 -0.123773563000403 -0.0644674103549745 -0.0213829646151174 -0.00411941865061348 -0.00223149476090082 -0.0427724549007613 -0.149191541965866 -0.00504009002754766 -0.157791851043333 -0.0743043756552578 -0.0294363436594301 -0.14356111506154 -0.450641930760886 fenoterol -0.396671653921169 -0.532641221028573 -5.46573256118843e-05 -0.550479144179562 -0.576665212636156 0 -0.29922579088986 -0.559310443754292 -0.325723448982703 -0.392092713262134 -0.187884091772511 -0.504105385425688 -0.656370492940493 -0.588289703940288 -0.440202593342638 -0.602095086453871 -0.350514049134778 -0.493219393446155 -0.660267733786104 -0.30346163542555 -0.367001039617042 trazodone -0.248446180168115 -0.768250639209465 -0.0177971908622192 -0.638052810810022 -0.691325211426735 0 -0.200005373122188 -0.740231441072308 -0.610169985037717 -0.754681324242556 -0.565549371630438 -0.681883817847043 -0.795407408290468 -0.822015585018779 -0.799630330930541 -0.774510012171456 -0.64262551322862 -0.758937562075555 -0.78363535133058 -0.179237714805998 -0.639778101352287 lincomycin 0.113088273185333 0.0258836271460124 -0.796333573665946 0.0323229029441193 0.121367203911557 0.473174989206897 0.27693527808304 0.0292410416802141 -0.0198034742247464 0.182154204752764 0 0.0132981209493234 0.189493701626882 0.00206780320234253 -0.0180595591198025 -0.0121550685915735 0.0206941620040278 -0.017690772961619 0.201481825756347 -0.137616886615583 -0.0448318040219977 flunarizine -0.351270977214163 -0.508236900749897 0.0209628220971325 -0.426909408681959 -0.607371189785296 0 -0.269247136555728 -0.638292416505967 -0.583918770673535 -0.697041799779053 -0.393096980211656 -0.563482613025574 -0.665477748864586 -0.694289839366215 -0.720650627235169 -0.688809800708714 -0.412591809498136 -0.649509044382657 -0.535682372199769 -0.45073829289343 -0.657447290627592 bufexamac -0.644806917639212 -0.657107003651224 0 -0.652411731584902 -0.644733378873736 0 -0.396072758173428 -0.692853086799037 -0.566871474651975 -0.674240317339777 -0.42953353145768 -0.576807278654866 -0.621102411513598 -0.732408591935331 -0.665730896733681 -0.718578442214048 -0.600051458513321 -0.583761125486579 -0.668435448923185 -0.430455459816514 -0.452497369934853 norethisterone -0.482653162591835 -0.629976334780485 0 -0.536872335141622 -0.474530451165021 -0.317692569595424 -0.534100954354361 -0.577704127855494 -0.465496808999396 -0.559452274508769 -0.497524029787682 -0.513439006388675 -0.646651566854596 -0.677341948429792 -0.645294321456238 -0.648478071790476 -0.506632964378299 -0.616805786667031 -0.632321722610566 -0.51096659473494 -0.481225230434436 doxepin 0 -0.526202984634486 0.327540599581202 -0.335249628976978 -0.212642279821296 -0.187259506285987 -0.493597867701984 -0.609838662923497 -0.432764805577913 -0.407125837885956 -0.487486735248018 -0.223740592328567 -0.407692081902087 -0.410969968768669 -0.456385575937593 -0.427701834941352 -0.345163933311946 -0.406120480813335 -0.453594657259271 -0.51567677647925 -0.340119978888565 cortisone -0.586243744123046 -0.645914747947856 0.153553370011417 -0.560848834573989 -0.721945362776666 -0.0825385295805856 -0.377651891327059 -0.696566123051601 -0.548425731588571 -0.624051701928646 -0.455323215841926 -0.588024299780565 -0.639469647803311 -0.671093542094723 -0.675922615499422 -0.693247554836118 -0.565352789662901 -0.639750598775169 -0.726647803587689 -0.532421803208996 -0.674132014679371 homochlorcyclizine -0.384937100234439 -0.354441418060143 0.271814984647871 -0.368249603132212 -0.136198731903804 -0.16412809213434 -0.369652343085445 -0.551556628456341 -0.311263073327868 -0.394490783431395 -0.294723760014562 -0.494947573960494 -0.262860033136987 -0.353787567801967 -0.444932637049958 -0.243959046456228 -0.309110073511927 -0.362564231200851 -0.332747050927142 -0.260651905220894 -0.222697426275278 glafenine -0.159905798171902 -0.476079122058396 0.121554029964865 -0.435387205172576 -0.333436594758229 0.145049325985082 -0.311919851168968 -0.330800936499222 -0.376812983510072 -0.413914640886038 -0.115375857505757 -0.481345154866043 -0.479929949711269 -0.647201044138754 -0.526306782148556 -0.481719266927494 -0.409404576990124 -0.576192247550503 -0.625871484165709 -0.40127633647263 -0.308971378981427 telenzepine -0.0865163104489683 -0.284807649177957 -0.137959613042952 -0.250731239167555 -0.260266876260441 -0.169072964778867 -0.362651433104182 -0.318651760608589 -0.220388703509053 -0.256541571091887 -0.091293281971585 -0.218373715110591 -0.283494194564234 -0.322576151257725 -0.298334740709286 -0.316731332021309 -0.26193711056267 -0.28403868156255 -0.343370490148125 -0.133721765799039 -0.498574801743586 aminoglutethimide 0.397079968758489 -0.152824149785071 -0.188367916919385 -0.0798691014227783 -0.0577909101421451 0.194294390687287 0.366560717360657 -0.116813680148708 -0.00237955095076446 0.0733813103583307 -0.0665821004080634 0.0754334672661041 -0.119316322319547 0.0358351812247829 -0.128960485682946 -0.127249809284943 -0.281774286882398 -0.124863839970643 0.0200745447787893 0.0791943390456039 0.0080840735123844 nortriptyline -0.5807623378973 -0.595306315247792 0.285620815106521 -0.387108913168334 -0.531786989522616 -0.330718996135785 -0.532565337985138 -0.672932818509207 -0.494682001761871 -0.652769579601028 -0.627027695203356 -0.589122708448767 -0.634481356492721 -0.64856452504104 -0.710202150026735 -0.641799466245091 -0.413900026727887 -0.526053801112063 -0.316236608093157 -0.579840199054882 -0.501012502884644 dyclonine -0.124046821608914 -0.222549408464473 0.257384279473481 -0.0832172328820002 -0.177842853206602 -0.122777650580965 -0.13033227050046 -0.220016149591484 -0.0801097183217746 -0.206535059559037 -0.2531058167995 -0.152946026920073 -0.242909718745614 -0.238589042938719 -0.217036200193262 -0.233393058964416 -0.123474550134505 -0.246193864086755 -0.237942797491659 -0.0277502796153332 0.147700190061891 diethylcarbamazine -0.442420719697145 -0.213532476180445 -0.00761156638616321 0.0715887425624204 -0.180013517955572 -0.131283573475498 -0.0376644490438677 -0.202985967248609 -0.22272537380049 -0.168947087392104 -0.185863285082663 -0.183673688051207 -0.232341209632907 -0.262739639026661 -0.196180013874928 -0.275144072965552 -0.165773622897282 -0.226317691681276 -0.234220057902507 -0.208138907489494 -0.249628512903743 pimethixene -0.377197566337439 0.160690924856191 0 0.0493369618888052 -0.521041316215894 -0.420384677475038 -0.477520981143433 -0.375080669800743 -0.0714079537107504 -0.0342042520596012 -0.443605353837387 -0.501783040770941 -0.413789359954508 -0.030722484163079 -0.054273879111064 -0.000344026979169872 -0.231349218601952 -0.389414346459772 -0.00743759247285614 -0.19332807082163 0.167265285560602 econazole -0.428862713124304 0.163658690490548 -0.0383674657292817 -0.00944728106368706 -0.197974992825703 -0.0693058605550019 -0.529025780023327 -0.245621966029306 -0.181235176662708 -0.111379905206803 -0.43085855258416 -0.339136027192322 -0.248286497104272 -0.22590734696555 -0.312688392231402 -0.201927081921543 -0.122001890755242 -0.22003234383733 0.288362369301312 -0.243571860488577 -0.158380044213288 enalapril 0.11386140001869 0.102411863648158 -0.216515547150581 0.129403887511201 0.0845868880059593 0.338399221700464 0.306827609720946 0.0789992708467164 0.102847084550457 0.094710289848748 -0.104669987806016 0.107348350178278 0.0835624754336487 0.0584338201770176 0.0836815312706265 0.0929051878987176 -0.0679140776289935 0.0779684734200339 0.060661344326327 0.0749666971396671 0.0444648424547528 dropropizine 0.203966874896051 0.0559566177033897 0.262659085349587 -0.0247574395784488 -0.201288258931516 -0.235853445506913 -0.0729901321271186 -0.0799930010085336 -0.0227799454583946 0.0448174682539085 -0.12692771337456 0.0726417801257545 0.0334458875383884 -0.110629022292612 0.034642282894523 0.0112249159752555 -0.159854213538111 0.0337607892626338 0.00162700365428001 0.0676911764338036 0.176842713378337 niflumic acid 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0.436040885628185 0.00914333726844631 0.211912352753529 0.0957918211106297 0.236503532275193 0.0245346693154012 0.111374736085032 0.108973687963934 0.276154543444364 -0.0281345370984535 0.0838355611681215 0.210540616239947 chenodeoxycholic acid 0.162759529032341 0.64071451524906 -0.139086838998556 0.591397148695807 0.440540483128286 0.338437201953852 -0.0726289268774012 0.592297497590156 0.515981030382726 0.601624712369342 0.294622363980045 0.606361670899585 0.649794791237001 0.634706880598101 0.66056768462708 0.63781248664849 0.426542166795657 0.4760148671509 0.616765579832274 0.291724198847618 0.356140464790719 pergolide 0.200618369182156 0.109143474774929 0.106138598244363 0.194899921653248 0.0407759836024336 0.16321583738628 0.167671361471837 0.137867271397774 0.334765273902471 0.399900028117487 0.283414787064693 0.269969423560708 0.255002268351132 0.150038515535711 0.376901858479104 0.104044238053353 0.076408485893435 0.0982360401191233 0.235345510262444 -0.0455290055860786 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-0.233251356442486 -0.0697357157383554 -0.182487882848818 0.23808661695732 vigabatrin 0.296846762656573 0.537932330577624 -0.0594756073338286 0.317034646012943 0.549662943556018 -0.0394700767262313 0.225784419979249 0.411762076928667 0.349836297768928 0.412800765347535 0.403397194105885 0.340672904559161 0.279116655644136 0.585860397968418 0.272864184040028 0.363663581298389 0.0301364536717465 0.515855422574413 0.429810795189812 0.0272297440786416 0.37102867957305 fluoxetine -0.293984962079744 0.17205574826508 0.0826642297783752 0.262979659936472 0.0810619911840697 0.00195285307800869 -0.287152398103311 -0.00909904125559967 0.183019769655062 0.302408860077651 -0.0712700179012585 0.0230997076352262 0.0227373346551013 0.175869552148972 -0.0117268918035194 0.303634795614621 0.0616254407326051 0.305547041654785 0.380577618105308 0 -0.236125070254188 glycocholic acid -0.190669683283926 -0.243703590498581 0.239906875145248 -0.0237241210793936 -0.39363573107267 -0.252370026072122 -0.194246297361334 -0.270264103879756 -0.0803269851119289 -0.129754233717651 -0.0825626815403601 -0.11525499866607 -0.1637561073608 -0.118691558897509 0.104713183681673 -0.156067405452613 -0.00241103049791663 -0.0168709092928292 0.00321264016294032 0.0162566089933153 -0.024537434268419 pirenperone -0.075549504587463 0.259749176603717 -0.182412314753868 0.257693185876698 -0.00420163442161183 -0.213394935116214 -0.0550418965624591 0.158749718420931 0.0145520327448579 0.0825746557529972 -0.00278316087290651 0.0859590541377074 0.28301853655213 0.251213760760611 0.314015975249523 0.104864101888311 -0.0108876620711813 0.151038229037223 0.356270533306665 -0.0735081962071009 0.0545522636986382 ciclopirox 0 -0.225646707708849 0.237117301951427 0.380742763446049 -0.22377957857224 -0.257900341603471 -0.448697426237971 -0.13651392706463 -0.111072754855567 -0.0863760949516907 -0.396191640552744 -0.322291284212707 -0.126184581291539 -0.161420003327499 -0.169497059660956 0.222120101226128 0.0457979628611035 -0.225980343406772 0.551111000843912 -0.255124193738079 -0.0956588492861668 hexetidine 0 0.325863037941331 -0.156369732466832 0.280341899788 0.326322455419541 -0.146741668548638 -0.236681374928537 0.27415671313044 0.334961700204047 0.371900428361177 0.00742981309579384 0.277750784281965 0.307486204118852 0.356204674289169 0.343722845926369 0.35873121682808 0.298872764856771 0.32184093249836 0.405564228536469 0.0669139430999027 0.102332036409676 cefotiam -0.0826529768207366 0.394744704304634 -0.44350010293375 0.158833382796942 0.125627705168966 -0.218012827463034 0.236026283231104 0.139557681248931 0.273723908087448 0.374927931727574 0.168042311147277 0.332424045184709 0.279685067763945 0.372940458989994 0.229478927984823 0.297603990598991 0.264677583342433 0.466492876027059 0.394775112169505 -0.0828419369260959 0.331769358040306 nitrofural 0.236333155662911 0.0521343898321985 -0.251969935036341 -0.180083856407549 0.125074738004921 0.097968699387933 0.0480288076911147 0.0135956652056196 0.124362735304664 -0.102116877648551 0.0500361649469809 0.0282310084935786 -0.0601565279473328 -0.0795805723298937 -0.0917639269515815 0.0647296577897264 0.0673097106286041 0.0683440544357626 0.16479908567731 -0.239184738891548 0.0483441863036457 biperiden 0.0812962637124949 0.646005623938709 -0.2434583524507 0.497403997007715 0.455114686633965 0.0985152200221135 0.146989112455775 0.517595578384897 0.550026418941808 0.637044106888828 0.255043432007368 0.489405214286731 0.610488465671256 0.64793567307154 0.65054153118898 0.572453622426552 0.251679245970916 0.632322947803407 0.691587368237579 0.11484875970184 0.248319764123836 iohexol -0.0229964823494215 0.40882976847391 -0.0256224037436476 0.497491518757879 0.41955617086789 0.502847371749607 -0.102413036531238 0.444712591819958 0.323997799652366 0.397241436972136 0.230045058569763 0.412811123316823 0.441059613007778 0.442392354644594 0.502050236684119 0.393210907285556 0.224958081743271 0.514225244986466 0.571241762882941 0.13891695487854 0.134832534272704 thiostrepton -0.488727627914434 -0.454275878953678 0.261302609852364 -0.381771429593554 -0.627677174019791 -0.32764893356389 -0.403390493040006 -0.672161005157062 -0.632768951996179 -0.671829206072205 -0.520771344249381 -0.490415065072848 -0.609906853333142 -0.672124130579847 -0.686852247058247 -0.61011700485684 -0.399995787244146 -0.674965227788168 -0.651958375767793 -0.144350630879052 -0.444163783432802 salsolidin 0.171690529999024 -0.487382042447388 0.11099836560212 -0.505446740185082 -0.246323549310957 -0.331430291365427 0.0571494868726058 -0.381985866009402 -0.312779075042755 -0.509598130800666 -0.346032321252562 -0.324436709854767 -0.504599483068086 -0.508196297741589 -0.389947315793409 -0.459276509905509 -0.341410116754481 -0.440968420236568 -0.37033871831987 -0.279483829092828 -0.312361191753281 probenecid 0.264785047437406 -0.181856774791941 -0.161334500497978 -0.336807682181672 -0.206294813434652 -0.190923645840141 -0.103357372334082 -0.277207127111122 -0.0170032354803546 -0.221495888810236 -0.112180796936229 -0.115147332266176 -0.179160626279044 -0.174675546784189 -0.184099660478057 -0.163270658402856 -0.303378112311649 -0.229836793591217 -0.322995011439019 -0.164442599173168 -0.186206862220737 selegiline -0.00697716094518273 -0.258027344038179 0.112309525805497 -0.16257103571229 -0.289475641841171 -0.155033557888897 -0.145234257552546 -0.272248801772606 -0.301496956255688 -0.350256507262583 -0.233150573103679 -0.233255109701089 -0.309898235346554 -0.306577947058348 -0.260072227534215 -0.160762849712216 0.0238055209561437 -0.184273909954192 -0.290341856853496 -0.107608209976365 -0.148816438924916 6-azathymine -0.196509831220776 -0.537220596889222 0.0107633700013854 -0.42078193450788 -0.634678309370314 -0.0887542171770127 -0.320248479978655 -0.631194303975478 -0.443836498142366 -0.551423592895197 -0.347860234652948 -0.491211268303742 -0.541263115914911 -0.556652345950887 -0.518130887404353 -0.525201171181672 -0.424812723107482 -0.515837923516283 -0.53768659713669 -0.35881831388856 -0.442509870144353 omeprazole -0.135964854353828 -0.681821394616855 0.239020826534406 -0.623781674046695 -0.646530198234509 0 -0.228444349102331 -0.676128037002549 -0.585553176952239 -0.689655049086212 -0.457027345878276 -0.607381622318562 -0.709239094118552 -0.736652006481579 -0.699170592008095 -0.678257453429474 -0.56961630794256 -0.644380871664083 -0.766896146573172 -0.289938623150926 -0.724040969185016 cetirizine 0 -0.662258481683622 0.135091668794265 -0.57628115131363 -0.604507641040699 0 -0.126439725773509 -0.628210425843521 -0.579044484467859 -0.678722495645135 -0.478246509434713 -0.571543284993688 -0.691378787185876 -0.708820534241358 -0.647340741203516 -0.666443780557063 -0.616334126882384 -0.590041070481155 -0.675286708577075 -0.398459451446511 -0.547805802864686 norcyclobenzaprine -0.531695884656444 -0.64258464596794 0.137798127191132 -0.573892218121597 -0.64015718603938 -0.204762641648409 -0.622206245493464 -0.649817960746863 -0.659546623904747 -0.700947430354176 -0.578930673143654 -0.662296791586811 -0.716552987809899 -0.684973850777054 -0.673569648002198 -0.616536614857761 -0.530077443333607 -0.614053788176695 -0.643281668827548 -0.432256671230735 -0.609957395005989 L-methionine sulfoximine -0.0622815222641238 -0.153998819795523 0.0426744499908524 -0.103348532763461 -0.226199797035977 0.0271661619412887 -0.0878043843884913 -0.183531665389408 -0.175983027951133 -0.150400701706175 -0.176353441793355 -0.085060693562296 -0.219299295320484 -0.236645266965117 -0.180572849881125 -0.136109873287818 -0.151873641647834 -0.204470672048854 -0.137668376802098 -0.12121116010155 -0.357070579610738 phenacetin 0.119570966938152 -0.361511875372555 0.0442802577953403 -0.44118449621597 -0.334880165955749 -0.092430880877627 0 -0.251859273767855 -0.282104431436196 -0.280933869088776 -0.101520570734875 -0.137346098700449 -0.265597426943863 -0.559029544223073 -0.38180583597408 -0.475671021690935 -0.223886077406033 -0.490319543027534 -0.396270549223683 -0.190196381307627 -0.379932383583198 betahistine -0.130125582900355 -0.647326060700478 0.268301226994246 -0.639392318329918 -0.518928444660407 0 -0.137218587274499 -0.499724564376778 -0.383888861083564 -0.679651001884907 -0.469704562436003 -0.550063828687151 -0.622221864757684 -0.564258812199963 -0.647923722900031 -0.646535327088268 -0.515410035005663 -0.613687188715207 -0.691500320087596 -0.524383107725371 -0.454729645568898 benperidol -0.0924608109400363 -0.373967998654705 -0.101234708799035 -0.394358373304356 -0.48056337947738 -0.171004375629267 -0.16007180001496 -0.500826166090802 -0.388205705673544 -0.439776388766283 -0.369144714902869 -0.414633780805442 -0.397648482675285 -0.497997787137113 -0.462049550921114 -0.355418696417069 -0.0512876999677671 -0.455353693653048 -0.487771470242847 -0.242505304736538 -0.0827279810840493 propylthiouracil -0.396273099289967 -0.624242759099253 0.365792947625934 -0.455142911678751 -0.639473380061228 -0.102181897125761 -0.272931258323424 -0.632065651948232 -0.51959370186058 -0.64339101969393 -0.392712519123478 -0.544587843050242 -0.632136342440198 -0.690876027933183 -0.516916285763539 -0.547211491987299 -0.343171013370905 -0.609884449788281 -0.675104950808211 -0.307204197165312 -0.506726928996831 etifenin 0.172861545804325 -0.288024835129608 0.0853944006555622 -0.196318853637371 -0.183640245798163 -0.084850339644539 -0.104257096415353 -0.304223187688363 -0.0037395837660153 -0.268387958036689 -0.0995478979646837 -0.138181117525684 -0.447466557061433 -0.287640261689706 -0.380696411554526 -0.202646559628012 0.058473411713508 -0.396249613772779 -0.388473376481898 -0.121400723925845 -0.351575384484829 pyrazinamide -0.197430391083398 -0.609198290047981 -0.25328793708763 -0.333992172561002 -0.454512975357177 -0.0922360793509819 -0.0621265587209111 -0.469203080015665 -0.450245749729717 -0.435829907567138 -0.397918183759769 -0.326907356173915 -0.579141205406618 -0.616028893822302 -0.605082632684893 -0.566204169882756 -0.367298121338076 -0.46976108315274 -0.594053206490964 -0.339863883972367 -0.283351785183999 tiabendazole -0.0268858682311347 -0.454802785784804 0.406546362016165 -0.517585531456916 -0.417282156804954 0.0448023914850231 -0.260394908042558 -0.458425908924396 -0.387153713559018 -0.546990234986391 -0.341803533661468 -0.440607428819348 -0.534525601565092 -0.556195283446714 -0.558513366659675 -0.522433743972995 -0.430769294016882 -0.478868133004656 -0.514542631250869 -0.0844605324269866 -0.294881906525548 atovaquone -0.0164512427007324 -0.410737044215361 -0.186217078509372 -0.484007679444793 -0.26784773777109 -0.126214442771421 -0.232272096053559 -0.418002306396909 -0.317153316157653 -0.518036614011959 -0.361365972934841 -0.217326315919799 -0.523332628348088 -0.441400729911139 -0.543905410843336 -0.416619368947139 -0.293593918109567 -0.376693045298172 -0.585385909181803 -0.162882278923439 -0.137539339186839 tobramycin -0.295785152310548 -0.583569956832096 0.227248840068799 -0.370523720498521 -0.62502935944786 -0.272522922229717 -0.391513699202933 -0.594272100556464 -0.48960351534072 -0.56300437671596 -0.339146012331419 -0.509770977102812 -0.567222341864105 -0.573864660020792 -0.550762798205675 -0.467653822474814 -0.343469445847441 -0.409604568767148 -0.463912213736436 -0.256204239051713 -0.310994929193609 tolazamide 0.0225226900999292 0.19632936855243 -0.0719580486607949 0.320675502920645 0.182828904868446 0.0897170532611042 -0.172317319314237 0.244741730156479 0.199104630487994 0.187527148055983 0.0822394100311068 0.282965779313111 0.220542891545432 0.196651607416164 0.288250218488463 0.207759220685469 -0.168838915902852 -0.0378786601307029 0.256865793772983 -0.133744334228981 0.00206822571628817 cefaclor 0.169290383019743 0.303111504212032 -0.0660968806011188 0.281625331393783 0.243165852586171 0.246596588196612 -0.131621607033902 0.252816041949261 0.195366628304391 0.117533397047674 -0.00990663228319955 0.210415162732034 0.25050303535069 0.223169701856739 0.140340123935539 0.302640043038121 0.314445045707666 0.222548283528698 0.351349028829028 0 0.373036248479735 terconazole -0.229169616494332 -0.351783439248804 0.0850909245441077 -0.326428537563806 -0.241752117981363 -0.331721755886753 -0.266355811640899 -0.381146948885226 -0.361167047973488 -0.342605043625203 -0.361713549997721 -0.318139630556088 -0.386896765727051 -0.34666573738191 -0.357128295395041 -0.326596859613517 -0.296362031989801 -0.355588278092296 -0.367783250198689 -0.359000879876961 -0.315332057326775 orciprenaline -0.00467158424073562 -0.289535447156017 0.140179717010587 -0.349656925434137 -0.000239098025916901 -0.375676122782442 0.0659303927318991 -0.231730671119531 -0.042027494278871 0.104151625291605 -0.252445931281878 -0.285460086449876 -0.364331374250526 -0.124527430107266 -0.0174624464185145 -0.11491290014558 -0.00713864802103747 -0.124279812183701 -0.308259032541747 -0.118570467856888 -0.220102897384904 trimethadione 0.0277622824021681 0.0190119585905781 -0.0230204640882832 0.0398487577977401 0.0122575073754687 0.107076215138592 0 0.0907928419525767 0.178926525802065 -0.0221512842914002 -0.0151076770881158 0.106935663419599 0.0338473647759947 0.191330605216569 0.208867002677089 0.0768946192755867 0.173634353667057 0.193978335547156 0.107963483977415 0.105544539976457 -0.102228700991197 rifampicin 0.328754950494083 0.336195271410048 0.167679925633024 0.162369851962489 0.444248560665062 0.359289567432439 0.199538940888029 0.268490009176488 0.409641090255296 0.157206626363712 0.430196884139539 0.348508941648008 0.327596136157431 0.151220479009299 0.29587445935407 0.329329858630555 0.111615505751435 0.26489312110402 0.305923672547398 0.132320425397985 0.171233562857247 methoxamine 0.107338302177516 0.259970629825167 -0.301810353104307 0.195435030702907 0.260859106772677 0.135100406804963 -0.00365839556372075 0.177181162431602 0.184921790598537 0.136975869152177 0.070037485342306 0.142418830993985 0.279292249981182 0.137539111158397 0.263418964757698 0.229714915656165 0.222981480797891 0.137478839896154 0.281019034482717 -0.079656500800521 -0.0909523082965984 tetramisole 0.0217338382487577 -0.107314427399781 0.0783503869916937 -0.159676884682783 -0.236511770790414 -0.0189861659809066 -0.00857509456119387 -0.132664863838342 0.0311592467027917 -0.197530536053107 -0.127289322770746 -0.0822016249365815 -0.145800595098739 -0.135756114757331 -0.10474522156343 -0.247072704445269 -0.119617648791118 -0.234982805515863 -0.243872870985054 -0.114581409520757 -0.132433983324182 nifuroxazide -0.13043204274728 -0.27023760547664 0.13282599093748 -0.259980417196006 -0.0809847822700755 -0.251787400393395 -0.410372003931367 -0.217813245149574 -0.224002281383362 -0.35599041013886 -0.305208641656837 -0.395626952175447 -0.378515119482915 -0.519242548860239 -0.368581263315071 -0.129839467520643 -0.342680434632794 -0.347487551890137 -0.292216084793503 -0.139504197685084 -0.111847126273982 colistin 0.0954205743349457 0.519509199305977 0.12303405577485 0.469820330014259 0.545838274338846 0.107899619158894 0.416864913737924 0.556261628730596 0.430936803251476 0.547923659250105 0.309623044928092 0.510712867182061 0.5165089401046 0.438415423944436 0.509851640077373 0.515822407296546 0.535687554245323 0.282038138494685 0.449044891956604 0.240908728028079 0.301045079405984 tiaprofenic acid 0.021792156410792 0.183770070198675 -0.0090621914145477 0.267055176299297 0.245089039803364 -0.016265617144845 0.132151465162243 0.260575303164412 0.15250804157609 0.178616875720129 0.0773261178259565 0.0360690252611028 0.246721783737351 0.147641000124223 0.238281808630972 0.156209728116456 -0.0866207099197125 0.258399460875118 0.0850182413082119 0.0638809588908872 0.312540045272298 sisomicin -0.170536939221128 -0.205542403062933 0.247698135459646 -0.152065460897441 -0.0685535801773813 0 -0.304653342431606 -0.026516136062063 0.0453679372719947 -0.190858803180108 -0.223857522621321 -0.0195282854982146 -0.0332574847557306 -0.0725978334649186 -0.134487479639563 -0.0909467466003057 -0.303024437317159 -0.184910436799063 -0.193598598464567 -0.278353085890911 -0.206332366429995 lovastatin -0.176306134149158 0.292708730367454 -0.164292708967053 0.287239593268649 0.534553418325634 0.281128041129784 -0.095414556141626 0.254142910428989 0.0170672638335128 0.301270393427768 -0.0526861909575856 0.0821634904455169 0.0917108062301756 0.174166752863824 0.0399341516985148 0.276932725189359 0.0712704877661652 0.160978077323545 0.197557004790874 -0.219390228082037 -0.120526616868674 ethionamide 0.186088832296193 0.256675123517562 -0.156783334148803 0.00432333495822159 0.165185788364975 0.297072311125039 0 0.288762380363955 0.236859069897537 0.123919450821633 0.172525105988289 0.307009580695353 0.411395384822815 0.368134658533913 0.257047220539789 0.265031758730063 -0.0414632662745328 0.261509288203694 0.219225108895166 0.201949092479213 0.0927856068031295 R-atenolol 0.182261345366132 -0.208671312520736 0.293963956153579 -0.144721272593422 -0.0788495171372004 -0.128854019434249 0.0918050685879078 -0.207480312646905 -0.135618832552348 -0.247663611529811 -0.0542021805478592 -0.222760430930091 -0.243793920287548 -0.251212542343504 -0.285678040987282 -0.221984353147915 -0.093534623235909 -0.189660469984594 -0.140845634416274 -0.0947052323527658 -0.27667523154533 pregnenolone 0.235327390071999 0.354529127117655 0.225783327123991 0.213426264824165 0.172997316530579 0.0826280080307286 -0.10625870225732 0.303110798204627 0.28891541317353 0.0563943434518965 0.184900965010852 0.0786997040682409 0.165560205366546 0.159725021792608 0.0459613400605459 0.264577031560292 0.356258612233433 0.354561310123419 0.441031660847101 0.233872580425102 0.386730620711117 vancomycin -0.000306327087890579 0.570735561527692 0 0.531801066555757 0.504609312063285 0.145625094477172 0.123288783518104 0.570062534999854 0.350171271082033 0.571037835986929 0.253315658877274 0.503867322350735 0.572914820840403 0.593656230010911 0.592964933634642 0.563679237776035 0.492404907954643 0.567168402062216 0.626215095255306 0.117964982130096 0.375741987013781 nystatin -0.402695154405709 0.474879926362042 0.344054903442025 0.287184955471294 -0.035585704833207 -0.355920279758926 -0.373612709627474 0.258939551477672 0.404366871312542 0.368717405582736 0.266609982693376 0.195408792991731 0.0368297702502046 0.482296390608511 0.173370745327901 0.321840451419216 0.390255863512256 0.491561084953995 0.662415368691154 0.297586668438148 0.187298596107704 tenoxicam 0.151342377396234 0.186603748370267 -0.268077682208894 -0.163663193444964 0.0905921246956538 -0.121663724267475 0.159650540121034 0.220275455223387 0.145191363284701 0.0994161893852457 0.0648191790292212 0.0916193053091366 0.217959737028687 0.191886561405556 0.210159720291761 0.0853100066394921 0.162298317817603 0.171270296769491 0.259164119655753 -0.153410142712649 -0.0184993236683556 suxibuzone 0.186735961546416 -0.182156407907247 -0.149440591993693 -0.257641962608224 -0.0555328707145579 -0.119016438831268 -0.0424405559125844 -0.0640790802555305 -0.0629586907676632 -0.292169190665755 -0.143744774576533 -0.000571493271752557 -0.182590061994917 -0.203674070462494 -0.164250121465247 -0.173731467520806 -0.14373628408788 -0.191056192315453 -0.311941740591396 -0.00290127999930226 0.314663039547068 skimmianine -0.296087915519825 -0.692947106567368 0.110276053791553 -0.594817901311973 -0.612346257632673 0 -0.122703898836193 -0.674134840186485 -0.556637395147949 -0.659431592789836 -0.489250585135162 -0.62213606620955 -0.709494651646213 -0.755805953424061 -0.76736917391901 -0.687178429868429 -0.460989062409637 -0.667950825136158 -0.736001079026181 -0.525920864653741 -0.596777767394546 ricinine -0.0931730174719067 -0.392692286283021 0 -0.317529118953346 -0.347068550881466 0 -0.218263182131174 -0.37790807569038 -0.352922106859729 -0.477792875567523 -0.308077701725111 -0.442869776699524 -0.369910560867833 -0.507713844661251 -0.463393848211782 -0.354824786293176 -0.304065842949314 -0.373986827019088 -0.321798231733485 -0.248791464402375 -0.418248242659017 estropipate 0.116879589729564 0.123336500463487 0.11485540465708 0.23679243061819 0.0870007372925408 0.182412303051514 0.162721142555478 0.192930624835849 0.214430168448652 0.0236977157077072 0.0420680421677719 0.196293094809717 0.190028355992356 0.117196276560394 0.17914952700852 0.209790741831466 0.201209128231398 0.0947257872516416 0.293840504245793 0.266416320084996 -0.0225087637679422 tetryzoline -0.235949908978562 -0.172266106305006 -0.170199207567605 -0.149867884769025 -0.171632149445851 -0.241728708813138 -0.306376525489452 -0.178459799812292 0.0132168469601731 -0.16033097679074 -0.214897755275327 -0.170765451657974 -0.190908409037745 -0.14693580992891 0.021819138437969 -0.176771837228463 -0.155652835771032 -0.135302052251317 -0.183257627125167 -0.330912251464438 -0.188092165153047 benzethonium chloride -0.453596397975443 -0.48380355009581 0.176118902122118 -0.560819973329708 -0.335655817864588 0 -0.370955803390687 -0.505634710870008 -0.309730375848049 -0.360664687062831 -0.233916421317 -0.448176641908336 -0.412538930678704 -0.387422612374762 -0.406572334467418 -0.452985497297567 -0.420567012372227 -0.470837026239484 -0.341960526370373 -0.380863738953858 -0.303063822159336 fluorometholone -0.163456897558416 -0.596132634847135 0.207957706802363 -0.390181646967024 -0.536007056666296 -0.0369363735876987 -0.219806478161356 -0.593024145342373 -0.416597905085299 -0.592873300749179 -0.435991237081929 -0.454243783535412 -0.596420557575787 -0.653812210691719 -0.625584034061256 -0.472696268475193 -0.573132709660762 -0.574616151345531 -0.628298288896006 -0.277766055296623 -0.0804821361430753 etanidazole 0.00683476870735622 -0.29956598420965 -0.0332290053511141 -0.117454142408854 -0.445527942653077 0.0657739137309172 -0.106769008047283 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-0.352895526320252 -0.418491855346709 -0.253734710960434 -0.278716234914105 -0.554186424402495 delsoline 0 -0.499685263942948 0.138318609626308 -0.43464389136013 -0.38625399456498 -0.0877059876644197 0 -0.491260625720771 -0.3614477610334 -0.452092281595941 -0.400029742028473 -0.38622413277559 -0.486857582984635 -0.550329477492076 -0.398925585109021 -0.502425370745356 -0.291108601120564 -0.37653194349814 -0.624117255428309 -0.308903453040866 -0.385933681600242 Prestwick-689 0 -0.177662272025861 0.11901966884658 -0.132076881516212 -0.416394334021371 -0.2705173748841 -0.106019168912441 -0.343632235585178 -0.259406714940658 -0.294281438577041 -0.121970554581285 -0.122628533860214 -0.179337137296251 -0.362046663205398 -0.324351384535725 -0.336108408924916 -0.385217589958737 -0.228150597369564 -0.462642533695712 -0.118640678897289 0.000403579541036897 hexestrol -0.432133682283783 -0.588013400560417 0.554498673123109 -0.563419730530889 -0.494904173054428 -0.158265714897369 -0.372989731022761 -0.653458066108385 -0.427783428237725 -0.637155884060801 -0.451638021198446 -0.582958904277058 -0.693364660089168 -0.649611905498528 -0.659938903491775 -0.597538068085839 -0.387043367592506 -0.593864362206529 -0.706171470259737 -0.373989482559003 -0.699649234701207 trioxysalen -0.292935875977614 -0.722335055605825 0 -0.63424577108411 -0.679081221111271 -0.107226639398302 -0.528591273033239 -0.686393956191364 -0.622739845916241 -0.665808551111118 -0.525186546097636 -0.600904732056303 -0.700781447464216 -0.772841808077371 -0.718276905355218 -0.710982861439735 -0.600081132260219 -0.68307024480218 -0.75071541239225 -0.218448820857507 -0.697475331736564 cefalotin 0 -0.345200870763418 0 -0.29879166572728 -0.339795385390576 -0.156281937545881 -0.14777080133933 -0.36292446790418 -0.289486092703489 -0.500354661279123 -0.347283452576028 -0.205450859361213 -0.353172242227692 -0.36491211088159 -0.340755396593236 -0.316170079010772 -0.30598714995722 -0.331362362051284 -0.434392966020219 -0.263397788403305 -0.43733062138612 abamectin -0.485596430028235 -0.354898990026819 0.240860073532818 -0.362028541181514 -0.394161468093018 0 -0.275276012309836 -0.454145859690042 -0.329202606362274 -0.37769214014097 -0.246880963214057 -0.376518257839959 -0.358610602579475 -0.364004809590782 -0.473238146091271 -0.364406072233009 -0.379298169068576 -0.358177969536882 -0.412117259359334 -0.321192215295417 -0.251647709278055 tetrandrine -0.0816469820559596 0.0811089884044534 -0.0391538085472398 0.105854493853263 0.0750560184768835 0.0509554956461729 -0.392940589191738 -0.140460598721899 -0.243701484424705 -0.296656441793539 -0.42927778789521 -0.148402142824306 0.0511333240021127 -0.0536670728377905 -0.204151846398912 0.108879688369245 -0.0311753989262303 -0.15829426522163 -0.118809428481835 -0.431121507460678 -0.152076728725134 fluorocurarine -0.218510440976253 -0.321861354404197 0 -0.11934710814505 -0.367610534581666 -0.258739529406588 -0.141970806656699 -0.392871438273115 -0.193508031111053 -0.204682598818111 -0.0446099658414714 -0.33171016829768 -0.149862742486443 -0.290857143708889 -0.283821079084933 -0.384861069194478 -0.129490452845311 -0.284418704539873 -0.224519584322284 -0.200081198032014 -0.335728856533459 napelline -0.111392688460054 -0.478410509619569 0.062267681528562 -0.19671789629988 -0.59358704922079 -0.157901151067489 -0.292947741662325 -0.377249627396718 -0.38101308001905 -0.357255016075312 -0.213946191632151 -0.350760978607967 -0.59261771030815 -0.529196519635552 -0.51109731420617 -0.49258066960979 -0.220210923713797 -0.523153389269381 -0.535169802871788 -0.377681646396474 -0.371324773937004 cefmetazole 0 -0.0835635152595723 0.140092448860769 -0.202551748742292 -0.0727826698485474 -0.150020622593341 -0.0360265017924012 -0.208808797275472 -0.0265812941450143 0.143522896009372 -0.00801325559081632 -0.0349925911819332 -0.218063409194835 -0.192379408429127 -0.189680312516319 -0.0366361806132629 0.00591558601637021 -0.18380439378504 -0.242833225606381 0.00297079544589375 0.0441548406094381 strophanthidin -0.377097599308968 -0.171530636578393 0.222894216680514 0.187528924925164 -0.0474744902444918 -0.423624426618266 0.220979709931821 -0.0760821310636473 0.0186218531958139 0.029194824892356 -0.285654655479897 -0.103456450186211 -0.0433075957645235 -0.18228073020793 -0.0811866660812446 -0.00790635784311712 -0.0171878708705736 -0.188937986996964 0.079185062389715 -0.0945636658131478 0.513013995582875 cefuroxime 0 -0.211936473041159 0.0823379490821735 -0.107877208549142 -0.251424283812374 0.0341976233007584 0.11741198291301 -0.2478775301551 -0.202812431257052 -0.240765794436615 0.00499761824722723 -0.0968867388859044 -0.229538773628744 -0.283339776266487 -0.288005482544873 -0.203923340721273 0.0278729610308268 -0.112569719020958 -0.301756772607067 0.165072522538075 -0.0518313903167502 altizide -0.0637222652012147 0.0771984093296717 0.109053010722525 -0.131851531891698 0.145196588841739 0.217764351673742 0.400392578111224 0.210305991166037 -0.0542247907227012 0.0680403003633592 0.0464983189723489 0.117384162933257 -0.0553708243949534 -0.0286195775879382 -0.0473290336930909 -0.00217996401860217 -0.0699699074218972 -0.00739156655092375 -0.215794450534007 0.109988894182233 0.108425865211574 sulfaquinoxaline 0.141369506376707 0.349279635443388 -0.0399996417837327 0.102423442581229 0.0796652464491996 0.189380700180136 0.13521615976583 0.204727765193431 0.158841654712287 0.250983460485471 0.0807894625594769 0.199905819052739 0.322144159109494 0.0596570703719516 0.239776966056804 0.483093998433147 0.169126591182898 0.236724154170696 0.261417458485125 0.108141596328593 0.0347096059024589 nadide -0.136895512397173 0.0243029782624754 0 0.0912756300601777 0.106636970626167 0.0322254760284761 0.100555791562784 0.100822784129568 0.167628518873578 0.296638708192114 0.0712130907073723 0.147484800512735 0.179129430766187 0.28829547772888 0.241740107267117 0.285298625098254 0.244769241754673 0.0404443175660098 0.3266851631652 0.0277111753678821 -0.0853160889325057 terazosin 0.167141648693709 0.582309500885826 -0.0968712603212407 0.449705126914255 0.452473550363121 0.238679412827655 0.440970273085953 0.553744020757101 0.394942898680784 0.562495382261977 0.211857989240554 0.481091993378723 0.594643294264659 0.641031523865495 0.62718649987753 0.483105433707971 0.274577140326289 0.365149376344143 0.44991460977877 0.425854391836321 0.320979265301314 butamben 0 0.145375433274096 -0.207263515371746 -0.0104198820404377 0.0724071683880047 0.111957803278158 0.243191144921455 0.120261990607633 0.304014970547978 0.10902519141409 0.130472881610638 0.127291746261196 0.231417779425577 0.0958380177136499 0.179244309377428 0.221856626685152 0.148673460354789 0.285604899674816 0.0686730466172625 0.278395899788811 0.205613857915892 alclometasone 0.0178944324592289 -0.0570801246337729 -0.301900247041001 -0.257537183175184 -0.126831030023073 -0.41476258197785 -0.227655966902541 -0.0764833453491044 0.00634713363074788 -0.179862837729649 -0.220134044959286 -0.106082671626752 -0.101017451502886 -0.20732054618955 -0.195430365151374 -0.0646933145827707 -0.276795796247215 -0.0625054859993777 -0.0546791641753262 -0.346961023018416 -0.294331987147395 ramifenazone -0.101807227394567 0.11335421136787 0.300824435769401 0.0273740928074183 0.0545302930525385 -0.0963063257971464 0.067961635979785 -0.0971495990540317 -0.0836850404236691 0.0910447567843267 0.0783859168195093 0.110332306010184 0.0936039618963374 0.0560134165330941 0.0749801147083365 0.108382497234469 0.21214621769718 0.119236161484331 0.0304093491243692 -0.0701841426456598 0.229492108673309 streptozocin -0.134144456226263 0.395837016863411 -0.421356710680461 0.427873838751772 0.379872857461279 0.023692842237864 0.0985569644020396 0.429333326011456 0.428997960623418 0.494946749211805 0.351027780255539 0.468284442250907 0.444529978350451 0.454821982332754 0.440369296892275 0.403815878533587 0.454007181055369 0.395333409129073 0.50117896706415 0.0912847668113087 0.520965070596135 sulfamethizole -0.229361660647922 -0.101250256681113 -0.068159624612306 -0.186859000297325 -0.338877232132806 -0.112280847784627 0.0603576827165682 -0.240299699426919 -0.0401764835306155 -0.283442527155456 -0.00387183078464015 -0.0878350490805835 -0.102412896065438 -0.0921044677880458 -0.230721477491752 -0.115933279580212 -0.145089548339381 -0.111917273763167 -0.414015708553781 -0.0492522393252466 -0.302679737921802 phenazopyridine -0.602508954688095 -0.351309159390644 -0.138604449138265 -0.439292820340915 -0.30218343496965 0.117215434941673 -0.43196297295969 -0.344741562780517 -0.274994210203706 -0.392175245201735 -0.488132223083936 -0.468752795595449 -0.474155696375316 -0.388309974604159 -0.495255641333251 -0.501792069528223 -0.549777366924739 -0.310034871232763 -0.49382250303393 -0.399051649125219 -0.29520126846309 sulfapyridine -0.444193563720937 -0.210208043139658 0.162211743256682 0.0105764027239703 -0.172733214214589 -0.174614564496028 -0.390528700881904 -0.0258730639460154 -0.207776324259598 -0.266055521384709 -0.133119833879533 -0.282319254597292 -0.191274663881179 -0.226454879313204 -0.045658720957691 -0.140598214683917 -0.17060305888827 -0.20617973229784 0.164866762431562 -0.348659356636837 -0.168781979412076 leflunomide -0.103604135525013 0.417809149700635 0.183554301747608 0.0479001577612788 0.366776913435335 0.0437929465135653 -0.0760039068262403 0.152471851092748 0.217449131001727 0.32898599407589 0.0917415421980985 0.392990624471667 0.146666678182157 0.289794782296752 0.288956282596399 0.277064147483395 0.225190066952362 0.412526729673378 0.17985216882953 0.0156861724092869 0.424770464061083 podophyllotoxin -0.146398574818406 0.530510713806601 0.292473905009096 0.440132909703917 0.595324361040399 -0.250084984311381 0 0.565930449270809 0.474538433601626 0.674108429743425 0.144177352703075 0.650350753206203 0.554763009949165 0.638682088834574 0.657724947399672 0.549411563427167 0.0763861077252605 0.525298563922882 0.701056536593067 -0.0782768276884371 0.401979890355937 propidium iodide 0 0.158360852970244 -0.133681564851228 -0.0123959687001439 0.16333218397369 -0.21666629262097 -0.15631867300139 0.142875927300371 0.259050752256956 0.136664117733843 0.0685554646342247 0.198485323220675 0.0729201759045024 0.138957264293257 0.170810875581656 0.146119882732648 0.0375716809830751 0.136088838878901 0.0884766373453899 -0.174850243242936 -0.0802625956721499 pheneticillin -0.10895178804092 0.58477707326207 -0.100559754196051 0.497740249891099 0.547415357157119 0.409975803562451 0.360752522601223 0.571669714137275 0.535417052330681 0.585520723773786 0.152137372671751 0.455133200879646 0.571349864117527 0.587945531540166 0.644231573652945 0.478131881225519 0.447537452681602 0.438835609302791 0.531064492980793 0.146831808393027 0.38954032555632 metoprolol -0.161021800540513 0.30317794509573 0.0383719209373553 0.286362288216895 0.316652017988462 0.193142582228157 -0.180216284865252 0.317725642286441 0.179232568327784 0.20639857142109 -0.220726566809316 0.199224299229024 0.278659642491459 0.303077718705759 0.312712874929162 0.290700299329909 0.0671986408316144 0.316312071048238 0.328362747918358 -0.131909226666446 -0.211486351437249 medrysone -0.542932163857957 -0.737639328787772 0.0923688217893022 -0.617143665596957 -0.735306424944169 -0.31893535640049 -0.492170939529737 -0.748855416864592 -0.621295088206211 -0.71841197137795 -0.438642854579265 -0.644906687950399 -0.75737307236451 -0.773597504554502 -0.73589539808535 -0.704875255306469 -0.567289201102303 -0.708884168116678 -0.73026026967907 -0.290562090236856 -0.339817526226058 demeclocycline -0.270176324859556 -0.449304200994253 0.252007628929462 -0.462677527045085 -0.5308891154582 -0.188413887869517 -0.162708513247401 -0.485523272386903 -0.35378103714233 -0.44890111860708 -0.342651429094166 -0.392384955745016 -0.434201333003868 -0.46948269452138 -0.446040955218349 -0.462094846210631 -0.279640506407799 -0.335589129457417 -0.59779426194289 -0.135548955733633 -0.309396324018588 meclofenoxate -0.00647900145422115 -0.459811474960051 0.0392478985737803 -0.405472729580754 -0.49250237625025 -0.0724489349927254 -0.179793566247066 -0.479590291025969 -0.417604778397469 -0.511674537672582 -0.307911900497131 -0.445679242979458 -0.513294122278747 -0.530445983927691 -0.509317769066395 -0.482930245591831 -0.312228243869131 -0.537561368929685 -0.502185581813086 -0.427846294517202 -0.333170372671339 levonorgestrel -0.098556286427085 -0.621787893526553 0.0328003720464777 -0.569160165245772 -0.618136908977359 -0.0973014866730818 -0.202556821955792 -0.664086855093515 -0.411794698345372 -0.669176327255803 -0.405248812475618 -0.613546350730666 -0.688834809174369 -0.698980745783816 -0.71882340854545 -0.619226175058389 -0.415376820223674 -0.627403951391813 -0.69291496952115 -0.430255924969458 -0.331391938146641 cloperastine -0.618720145833615 -0.581463843542235 0.0910340983061833 -0.498416975363304 -0.654714017482824 -0.331344511255667 -0.500967430270358 -0.664453589113268 -0.604796230447792 -0.653288459054788 -0.531045773654009 -0.610037681042872 -0.658513943544088 -0.657396702327498 -0.702754094509704 -0.607261485751017 -0.514050526242619 -0.638126738420273 -0.481642484914571 -0.532893164622584 -0.469112063818849 sulfamethoxypyridazine -0.195975592055388 -0.483153842758327 0.253640046189103 -0.387568248414012 -0.421137693307454 -0.0498829201060203 -0.174425512110176 -0.460674664711756 -0.496407925639065 -0.45641049694231 -0.438850744977302 -0.480479025090027 -0.466468716616635 -0.508314165299236 -0.468689631021615 -0.482009523908135 -0.332372852732745 -0.442727410296473 -0.515711247035304 -0.285503680802019 -0.396684373691053 flumetasone 0.0352376626475108 -0.400596656423263 0.119630097357689 -0.247505212928359 -0.362154173577477 -0.249032610305376 -0.0939910094781719 -0.286412551716534 -0.28901727518707 -0.386860878276085 -0.163098592202568 -0.413419125217874 -0.41952138143949 -0.523171746621227 -0.475748397429431 -0.318620851714397 -0.293224690791667 -0.410375728492046 -0.55153833022015 -0.317304479625544 -0.234866140886142 flunixin -0.0463827272383279 -0.462983306882203 0.438655169167494 -0.439820952220037 -0.360214202400511 0.0195020651552075 -0.060622355212849 -0.597475679353944 -0.367883104231969 -0.555256804477838 -0.335768290536467 -0.311758064928147 -0.575761295524282 -0.564210799857561 -0.624115241285663 -0.543065968407382 -0.464103389071828 -0.531092611913216 -0.66320303505308 -0.319434797857313 -0.305690794736038 fenoprofen -0.115341857451469 -0.587793095101735 0.180156343022771 -0.433468268531575 -0.517866290438995 -0.391339770735863 -0.155329607431891 -0.483279985932606 -0.431145459452575 -0.496768463019165 -0.30832669817443 -0.459024835039352 -0.519890836566707 -0.584335836219688 -0.466892445316446 -0.586679594316237 -0.412713977251172 -0.518416130074376 -0.500534994605524 -0.264653693614567 -0.479418421295011 furaltadone -0.231867844514899 -0.386010154899372 0.146667492881535 -0.383648573804068 -0.467286235386042 -0.146151115995268 -0.191929718205932 -0.468902437259924 -0.338517028047627 -0.388558520812244 -0.162163587375606 -0.323553531025076 -0.436951711060533 -0.473983891522179 -0.429375353135569 -0.38952681228097 -0.145630060778085 -0.376830066544033 -0.459652333659016 -0.0553491756798143 -0.297634308248227 bendroflumethiazide 0.0508513334910961 -0.363403656507668 0.37060950023612 -0.339765594482238 -0.425486881159112 -0.0668516726010555 -0.0590645209436115 -0.423122363382347 -0.0714627894815304 -0.303282838696921 -0.186393487357888 -0.354150531227263 -0.439667022611047 -0.455658405131705 -0.308449463227811 -0.257752941137089 -0.264081123405767 -0.210535623995876 -0.482030485908781 -0.140521737400223 -0.333108821749708 eucatropine -0.179755267673328 -0.598331633744406 0.20980150232543 -0.426628368400224 -0.634466349976746 -0.286906378672091 -0.249315449279085 -0.658027373577647 -0.467906555440259 -0.612704824546486 -0.380938014995334 -0.549693514995488 -0.623264700721187 -0.643026454423991 -0.605221597619399 -0.598646103745111 -0.397384842772543 -0.587908617401054 -0.571150563637467 -0.235673599338178 -0.536048434478417 flecainide -0.045916593624005 0.04679166963801 0.0567767473855678 -0.0433583595677559 -0.0205405733567249 -0.0967763838132841 -0.0505594803437466 -0.039374549770474 -0.0479180009670397 -0.0380988762798344 0.0213093199737081 -0.0414211005570779 0.0156469634782507 -0.061854399752353 0.0387900075483893 0.00453977801826334 -0.0811216602242126 -0.099023951998131 -0.0231173433227055 -0.172002704661087 -0.181662587055744 spiramycin -0.0687877508457705 -0.173313814098445 0.206340479837334 -0.161208521629937 -0.176959776815998 -0.00898398969777504 0.0741073250516858 -0.267821578022698 -0.123115165160146 -0.162822800158866 -0.149712800212697 -0.0978321560198635 -0.0924219552106052 -0.103468687134232 -0.184559390498009 -0.0898227765744242 -0.160269182134224 -0.173022368886675 -0.272769901299009 -0.0830513771319845 -0.29587659243755 ethoxyquin -0.324438678695219 -0.11843969266579 0.0318993246856529 -0.0771734416555437 -0.0358210917132493 0.113788546468353 -0.169688205376801 -0.0224783612713889 -0.039011886197437 -0.130546301944195 -0.257110569508145 -0.193361630161965 -0.182949960788565 -0.275418975834581 -0.275036765110037 -0.202067092818244 -0.324715396555125 -0.255957135514761 -0.199350893252625 -0.307019770698514 -0.23522260758891 sulfadimidine -0.242196873435419 -0.246497241611692 0.351516807648331 -0.14488007138785 -0.215998720476952 0 -0.0951237957373566 -0.235090221069864 -0.265099105183181 -0.298442831724818 -0.0865575930172966 -0.253441269747653 -0.176269097538045 -0.246587882856534 -0.215436424790113 -0.225501990755761 -0.15482178955766 -0.220256600337695 -0.313358589936718 -0.237557925439784 -0.0896502858606654 dicoumarol 0.125956997619435 -0.141692314169881 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-0.207852594601135 -0.364985904528346 -0.39978383683147 -0.404391786880769 -0.332020916076438 -0.150934124183011 -0.156596978294046 -0.377350022443278 -0.237302801604543 -0.447913343219523 cefazolin -0.326182902967813 -0.210371486672714 0.165255475121607 -0.157120852316923 -0.138254560954985 -0.320150730317634 -0.119425660973826 -0.119801339529711 0.162289991026001 -0.0361241504954848 0.01122426230538 -0.0895183721691093 -0.130427400030735 -0.139308825244902 -0.171604093994359 -0.107196598241435 -0.000412757064713287 -0.109211222514288 -0.177346878433809 -0.0805244532886946 -0.347353924886572 glycopyrronium bromide -0.0473336834409833 -0.295784925764428 0.170706292919953 -0.115926453083144 -0.212217491641741 -0.307593333512934 0.107011085279059 -0.306047416387848 -0.111643024002002 -0.149216591754132 -0.0581235460917134 -0.13871809125538 -0.189852919512491 -0.311421595787685 -0.188274024933553 -0.280680969851115 0.10777388221069 -0.318301255044529 -0.23400517470236 -0.0710065293536308 -0.19975036358117 diethylstilbestrol -0.0615497476070491 0.459854219621321 -0.01196410557605 0.12942640390437 0.406834648018347 0.00262473723703321 0.0124739318449795 0.425099206465713 0.379992848013848 0.414518727329575 0.137759675479866 0.411203742151609 0.271135637357068 0.449486858627048 0.391134457833656 0.38934592729787 0.433272599929765 0.184598672445195 0.352860399304507 0.145470766016885 0.139377183908463 tinidazole -0.284425164431738 -0.113135673044979 0.129270163923449 -0.201002186002748 -0.281607574230112 0 -0.0825608706355086 -0.149966728548363 -0.253835090794382 -0.231398853934137 -0.1436436311749 -0.147857013000913 -0.219633843243017 -0.234253984990747 -0.29244817317136 -0.254964954806853 -0.159721888961504 -0.200459242449716 -0.380122212682165 0.00960274748385855 -0.097296519951103 guaifenesin 0 -0.124754228049139 0.228795669615643 -0.10501879413028 -0.135939361515512 0.240448957859917 0.178475099940346 -0.0650087013633149 -0.231117669220449 -0.0759719746690822 -0.18265600204541 -0.147575672335322 -0.0687868099602951 -0.144675689087074 -0.175201937089807 -0.154433493227923 -0.0463142931079987 -0.159724277175053 -0.0951513186522968 0.0876579572524833 -0.185247378735186 thiamazole 0.0973594281523679 0.218410694648336 0.107636224086022 0.264350755405014 0.0851968279819393 0.133099898358507 0.172310135979009 0.250678098387798 0.346407370748442 0.162031304207254 0.0572604814729809 0.148733438040814 0.195687396994773 0.220581690837657 0.0756800008934818 0.219983321736632 0.220255175257946 0.221372314128243 0.132371343409667 -0.0217230832374773 0.370166509532615 lithocholic acid -0.21556220176898 0.0738354821319004 -0.0677615620033993 0.0223195689540337 -0.00152481975632538 0.094963369891432 0.164087498717412 0.0283096739634338 -0.00983541403881088 0.084598736435707 -0.0563056884051319 -0.0832656165738318 0.118633980665381 0.0599101752601373 -0.02751972184213 0.108096024179081 0.0766840307176294 0.0547052970609637 0.145536329756301 -0.0292906442080163 -0.044882038557934 alpha-ergocryptine 0.00384046733620144 -0.0483209511811195 0.00271398695493875 -0.131509117170843 0.0444158149334359 0.153103007336368 -0.0122182661104214 -0.0760319040472734 -0.0304400628298253 -0.0411419936239643 -0.0677143207220577 -0.0339478413091875 -0.0548247565798579 0.0405074532628975 -0.171646671923865 -0.126033402910454 -0.0423415130651995 -0.104008431703522 -0.166790627477869 -0.0504376233414183 -0.0124173200751292 atractyloside 0.102269282602866 0.62314540251727 -0.0892095888096704 0.558682373549612 0.620480787385177 0.142218501776564 0.292228891820477 0.628607293797897 0.59635312240757 0.602271075052323 0.435751860204141 0.510112038083602 0.672485393095045 0.631081107779723 0.648116887122858 0.62423127958021 0.510719890541728 0.578003984475099 0.655803572835528 0.485798875096579 0.335779595138988 guanadrel -0.0118692559444668 0.50185089104392 -0.0534461153958455 0.472826547250314 0.300136445103584 0.220047726819436 0.204013348781364 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0.229372331340355 sulfadimethoxine 0.131934760327065 0.654113638377576 -0.36938671794583 0.634328478336345 0.565117865851921 0.153055568353671 0.310232173359268 0.577360606546727 0.524981324957916 0.567239870787551 0.363342309613513 0.572421934042787 0.679738108478728 0.615676509339376 0.725637477964384 0.581898761585241 0.570892661942396 0.630513197596156 0.717544208012142 0.444006984615646 0.221268942307527 calcium folinate -0.203795366880767 0.535094791699093 -0.0286690872818599 0.541274007672144 0.36889509454585 -0.0694132584356866 0.0848374162577077 0.608049557405541 0.532965859687934 0.638738065867823 0.322300940502194 0.424184733559141 0.579836536861137 0.636246298015887 0.57105866666166 0.647559157678204 0.506063130890838 0.589211590575217 0.632138698254121 0.327151655359808 0.317690008201756 mimosine 0.142168877489297 0.174036101183036 -0.193087867880454 0.30946672161483 0.32321243566388 0.0923387408490683 0 0.562598690765069 0.282196081753872 0.115721157472672 0.280517814230601 0.139750257954076 0.289551110896227 0.272603505727266 0.267101773733464 0.448993969376459 0.245126747958856 0.160676688911344 0.316345158161669 0.264710043087056 0.184565080440291 ribostamycin -0.288957598026387 -0.310466089390292 -0.268888400889569 -0.191659976287292 -0.283561261852669 0.047585554466129 -0.131867656345242 -0.254356645219299 -0.102014421977379 -0.312844555306515 -0.231565066354434 -0.212238834399726 -0.264818050994361 -0.292684621485705 -0.279903951932551 -0.300343706178443 -0.105017665783599 -0.289700791675578 -0.310082016741919 0.0234269902541829 -0.295652213510746 vidarabine -0.150424085857764 -0.485266617132369 0.267953130319991 -0.550403774808558 -0.61101744043589 -0.234913629714705 -0.130445766057506 -0.606852609080243 -0.39279529437776 -0.49561490817869 -0.205080040317722 -0.478815907165438 -0.411845185684686 -0.649821226458122 -0.513181989683106 -0.516357775650712 -0.492616961762609 -0.62424184123849 -0.456888510118551 -0.350028545937257 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0.469942106883825 0.550102102563061 0.5164987474492 0.554980214084633 0.431333713722121 0.528250451284658 0.191670257907618 0.278059376815394 0.366803354138742 methazolamide -0.164110491705771 -0.621696416637566 -0.0304555862962223 -0.574144971461519 -0.605188838796583 -0.429181095759657 -0.152871963579882 -0.494238633895437 -0.516014028094013 -0.589575592912946 -0.345797171241895 -0.535899300454805 -0.619036888160518 -0.704232808094076 -0.62666723249571 -0.643843806785854 -0.525807604073121 -0.460366603571142 -0.677004903737528 -0.163436034227763 -0.44113733848005 clidinium bromide 0.144038061277463 0.297959140344412 -0.125639093997664 0.296241474693671 0.310390535493594 0.256008752521719 0.318037761944249 0.341829868932348 0.0417629310068167 0.172539822710057 -0.0311042086298512 0.317708626742397 0.34186820706265 0.304017983417322 0.349858138264383 0.296435453558776 0.12089724083596 0.146331037901287 0.186100138381642 0.141765915510459 -0.0106924083818956 cefoxitin 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0.230874569864303 0.198448287972467 0.376474049123679 0.38234788638946 0.252045454681654 0.239481875918573 0.299337855538948 0.230259490841637 0.385305240828474 0.135736564111537 0.150114637279818 pyrithyldione -0.0653347214229835 0.46474622711703 -0.548274197970682 0.294650571663165 0.376762571239525 0.0376593549396268 0 0.465053590421631 0.386239563334186 0.564626587253591 0.276936365463292 0.396521743319721 0.480822254433431 0.47416113107286 0.495145080914001 0.453608433054105 0.23550122754489 0.438479119433362 0.495095147249993 0.141119624878213 0.118174778314976 sulfamonomethoxine 0.0772794548090417 0.550478706030258 -0.478733564064951 0.534304305805596 0.476904869752566 0.204704653957132 0.187850596377943 0.570494275646012 0.493037754309208 0.451963650405915 0.28714380631562 0.45718792737502 0.563688061979831 0.450974674905815 0.467774546959553 0.536061937773771 0.441210401353727 0.433322831052353 0.67944232642132 0.29440407653591 0.339596434975193 DL-thiorphan 0 -0.858569352548301 0.386339059104216 -0.816387942304937 -0.803160250271214 0 -0.292550433499206 -0.852763632912925 -0.574656551704826 -0.793248320583578 -0.438952970742296 -0.68076442379483 -0.857660699112541 -0.882868411110228 -0.825769067254294 -0.821602729408337 -0.306731907131092 -0.839386360674543 -0.8173696845004 -0.621104310761775 -0.742561022370205 alpha-yohimbine 0.154398828957227 0.231853821104782 -0.0954721184909519 -0.0626922200694266 0.203505361485921 0.141467821361536 0 0.216950102117329 -0.148541120783997 0.0467541741210201 -0.0863530541916347 0.100160878956463 0.19257142917668 0.033533771934068 -0.0701531175372452 0.0511935091001786 -0.0851465699310626 0.0481190245952364 0.171968227740322 -0.0997876502169581 0.131344513191522 corynanthine 0 -0.537371722511607 -0.0285463756907037 -0.495698275504323 -0.509500758124508 0.145607958567677 0.135330695040743 -0.51697532875784 -0.542055056841804 -0.532913858459904 -0.263115112462963 -0.474138266671662 -0.381218721236549 -0.393955651714515 -0.394193584395809 -0.513977698413251 -0.532193719542502 -0.657311420071074 -0.728698947531079 -0.203031622835811 -0.467727118043602 salsolinol 0 0.0664295952108418 0.129917450440952 0.0678118676328625 -0.103110712059473 -0.0648378639312062 0 -0.0603991251589524 -0.109458325701259 -0.320937607360857 -0.147109152568479 -0.146301275897808 -0.0850709849068773 -0.0976002101303575 -0.117458726159218 -0.0654484520507176 -0.126655950688908 -0.0826150919361179 0.103385197194244 -0.00201684530093208 -0.256738117611424 Prestwick-691 0.151490935422743 0.665961563260367 -0.344874032195787 0.616914042769889 0.600712555661257 0.182130261413699 0 0.667392970667864 0.554453865188605 0.59650461413013 0.433914961370823 0.442313563498398 0.695241612790096 0.669000130188184 0.65925124754508 0.649986483941486 0.411507469562373 0.6715131184415 0.680283780232472 0.345532123517902 0.248259813501798 mycophenolic acid -0.19246890561232 -0.0135582563866198 0.13227785772367 0 -0.386103715805541 -0.526607494956085 -0.38741277198686 -0.260146562831921 -0.323507321641235 -0.346997595494974 -0.310890017919544 -0.312239564626578 -0.177565499762122 -0.173212532725046 0.0375045759451217 -0.096609777207055 0.0230225087514186 0.0752771853702542 -0.206190768242114 -0.0167949885197489 0.195695431322341 harmalol 0.215952665641343 0.317425842923876 0 0.156484695641523 0.328703816702068 0.390857275374501 -0.100271548127638 0.192885904173402 0.324790427213636 0.461344802377586 0.0500630794658438 0.130481118064056 0.314134523648297 0.346503177776912 0.253843100892665 0.180340841703152 0.16962392178596 0.16898087115414 0.472094901052235 0.0983427199779965 0.296044308803777 metacycline -0.0257348546595863 -0.513237511050752 -0.140078178875779 -0.471781935744208 -0.441906997055692 -0.0709366011840881 -0.0734648491451808 -0.520097010420094 -0.385343276935427 -0.398711282145543 -0.248442461401143 -0.263299117258824 -0.511158078278902 -0.511622869621675 -0.349849861504331 -0.545705350606814 -0.359315557667515 -0.413280116367127 -0.635326239228671 -0.0720078590428334 -0.109285239722571 pronetalol -0.00363140484997246 -0.374780961912105 0.0784615564434458 -0.417716605042546 -0.333690295030679 -0.0321118474301187 0.101135595959211 -0.426859508137298 -0.359015954597888 -0.340720936582061 -0.245255981397121 -0.282421581821224 -0.370523614286709 -0.369284210867606 -0.33570810654037 -0.355540562765709 -0.300926453562303 -0.42661233638112 -0.613694870714058 -0.105842241222966 -0.306873472481153 Prestwick-984 0.0169013034876411 -0.0753741259341154 -0.0352996758604279 -0.298058233856325 -0.00953285000720797 0.000396989017851387 0.176026726544164 -0.147385439618012 0.0693957469069052 -0.12903618032589 -0.0236129618131227 -0.0574293952982528 0.0806889623640592 -0.110686754429682 0.0521306035595893 -0.221533912817329 -0.167009597720435 -0.217071031285847 -0.0956781906650435 -0.238601171022972 0.144913197213499 cyclopenthiazide -0.0306065123645676 0.0322732230639104 0 0.159221888116224 -0.0380566168596319 -0.136729273026045 -0.0297881323805048 -0.0317682805141369 0.266785947430829 0.0629086950601025 0.156669325141439 -0.0342367195600082 0.0499599279495511 0.17253259621254 0.0207160972780675 0.0333985969086209 -0.0175637662790029 0.0373559016309995 0.0965029953504469 0.0480528350657189 0 meptazinol 0.0662002430862014 -0.628941412093224 -0.122044462764293 -0.632290378946739 -0.431876729742003 0.266715900289543 0.0703325475767479 -0.460056017232882 -0.391107500134005 -0.609865259572714 -0.324311333364854 -0.412778494556951 -0.499555865613521 -0.516506291637675 -0.502778844059931 -0.606826931884216 -0.580135940689137 -0.619158726045835 -0.485267039922233 -0.560712229872489 -0.446057428994012 etofenamate -0.00917649856179817 -0.412203207778762 -0.0296933465605595 -0.553036118760339 -0.336856942216838 -0.00824989167896545 -0.288132214348796 -0.383623005562673 -0.42901695719632 -0.550236813270082 -0.383819410322846 -0.349257296740948 -0.405780847552753 -0.452741942441933 -0.41824138516743 -0.431963002447124 -0.445929690897143 -0.371253154638063 -0.678928300906181 -0.465895047372995 -0.486237725900079 nifurtimox -0.0298433198316348 -0.0452126065627195 -0.108764451113854 -0.0695690236808658 -0.1467065504498 0.124498761108622 0.131479121261131 -0.182798689278039 0.0408820372339606 -0.185921964708046 -0.131943234264064 -0.163599271132087 -0.0233909049253265 -0.201532428133784 -0.0260022854907773 -0.215003751364821 -0.129596297473538 -0.0433766614984222 -0.0595744490703289 -0.139702683714094 0.114852519328637 pancuronium bromide -0.1526254198918 -0.412616772953644 0.220248580785267 -0.342613921104726 -0.553903464336612 0 -0.116926043178493 -0.430739328482929 -0.428783709413993 -0.572256433185646 -0.258370299513497 -0.35500265834386 -0.440865251620776 -0.448150865531458 -0.431520425437588 -0.432189281652138 -0.31353169318865 -0.429911302124255 -0.585874892712824 -0.0516707501913812 -0.492243569094395 gibberellic acid 0.196953216093404 0.0408606654196907 0.0321720160577179 -0.0382025896220874 0.152304484775213 0.126682618471016 0.0538444141374154 0.0722244316945885 -0.0754976902759213 0.10561553195152 -0.00173432806949847 0.0117234113370715 0.0533806087586813 0.0320768818973093 0.0421600855574527 0.0420303661514422 0.124049646166165 0.0613075157327649 -0.0397614091562114 -0.0507160472708645 0.0035540035464709 naftopidil -0.00484528874254044 -0.432062060298557 0.103083400935829 -0.493376545754046 -0.243119452977829 0.12504513545037 -0.156262854184941 -0.114912052544304 -0.293588717869307 -0.461955206997355 -0.0873878814215531 -0.260604669588698 -0.262057513740447 -0.269394454651275 -0.446174534072206 -0.266421105583518 -0.496358926076983 -0.535056265221283 -0.653814581433393 -0.150565590638688 -0.423454170925195 sitosterol -0.0143467435389544 -0.536663850080821 0 -0.50263163319725 -0.587126759003657 0 -0.284670055000595 -0.590950489546263 -0.587607973619794 -0.562691158450962 -0.278316385521753 -0.425277192088684 -0.598982433542147 -0.623129716645847 -0.524048186924259 -0.585335090587253 -0.429575362415072 -0.579923428299055 -0.66879497840684 -0.358434318082531 -0.219440352976596 fluvoxamine -0.101356691350474 -0.343582455341336 0.0972103871223537 -0.249338084631191 -0.292657112081742 0.141430100262133 -0.417791490681447 -0.355721773007023 -0.337894404583855 -0.371330164779756 -0.30958474011201 -0.333188967928538 -0.412897094026627 -0.390632287730231 -0.395324599807213 -0.364699616549722 -0.43807196179381 -0.320397281438389 -0.369933239648844 -0.3933795925907 -0.373818649382378 apramycin -0.102493046883141 -0.664728706562774 -0.0874442403720017 -0.6078081903435 -0.587322294548902 0 0 -0.634940175768725 -0.48645321790095 -0.641338665880327 -0.350931580275696 -0.573207289873194 -0.540374931339194 -0.601006584337124 -0.560849577239964 -0.689039272597855 -0.440978362985861 -0.502582989112258 -0.77095264615505 -0.273480795301888 -0.168579560979573 etamsylate -0.288146322133708 -0.598892179881672 0.175650257517425 -0.403538402187592 -0.597776492441859 -0.244095342547472 -0.361282544281564 -0.631135394798486 -0.558179763479664 -0.603354400570356 -0.422885260688485 -0.544631466716236 -0.52309266047334 -0.632910725166816 -0.643894254759619 -0.608573684920826 -0.441730407465026 -0.550511527298644 -0.682271038634264 -0.271448030589265 -0.520853879755739 letrozole 0 -0.0302524470354566 0.0318416301634109 -0.0313217544095712 -0.114168094080846 0.0641556958448089 0.0597412081062926 -0.0165805378508538 0.0933578058870575 -0.0418350675148894 -0.00561106207362662 0.00742290622191208 0.000541589695975425 -0.00725770657217864 -0.0482695366298434 -0.0434165187530136 0.00897711085623754 -0.0492186998946879 -0.182458040572333 -0.103437907837786 -0.07727209370653 molindone 0.256803899608039 -0.414979635028775 -0.0376310745498395 -0.52962616579908 -0.166190431316064 0.33159804299966 0.1957429739221 0.0854568568575446 -0.130227121603411 -0.319717882376267 -0.151906284214169 -0.00706719444382964 -0.0880688191535938 -0.433086950546673 -0.289142016841809 -0.314334758036414 -0.487794607114983 -0.284685501817062 -0.363604815432017 -0.408340060994968 -0.162574787942386 sotalol 0.182535219901426 -0.257152099416296 0.121051474268404 -0.194204320161209 -0.242930978268017 -0.0507265948450813 0.197960991754574 -0.235678436642892 -0.265746850513527 -0.247370366504367 -0.075703801528768 -0.12051628504774 -0.254575432074543 -0.297763481931239 -0.158441318158564 -0.260147164130287 -0.0965944657535054 -0.24535674333328 -0.324992255400171 0 -0.203087314417588 tracazolate 0 -0.553783321470096 0.243390296965685 -0.32095471294581 -0.485032139373464 -0.01296273353744 -0.139160258999711 -0.511218476962232 -0.502405995334208 -0.526466990172921 -0.425802129452569 -0.454756894542549 -0.663991990654015 -0.436123791988198 -0.701479584748171 -0.543918851576031 -0.318085199439801 -0.510924227442487 -0.454311799656356 -0.302709331265619 -0.586886086787746 proscillaridin -0.298438014703934 -0.593859374745883 0.18661794163142 -0.139911412011095 -0.545938242341478 -0.424488596489624 -0.024422863174189 -0.285814166824705 -0.500617393146662 -0.337931651231224 -0.266284535455946 -0.163431446019843 -0.544173285736699 -0.38310373972226 -0.351819952698628 -0.330797900492512 -0.28494117560373 -0.52022268118186 -0.219407783016522 -0.106309405150696 0 cefalonium 0 -0.214391549952237 0 -0.221547492667315 -0.235355062546233 0.355244455737827 0.206272566488141 -0.0125080465416186 -0.255956417177411 -0.471635148419651 -0.0448908217199243 -0.156992851434801 -0.063000321692035 -0.0806261804953813 -0.252429679290257 -0.238786043374831 -0.0413143529899465 -0.226449817204098 -0.495833899627114 0 0.0665936481535704 epitiostanol 0.362453610278863 -0.0892735406789811 -0.136990454856396 -0.0216109167242786 0.175303596703831 0.434623158753235 -0.220013936956341 0.275451849588612 0.183765484446342 -0.00847944719483318 -0.0216622031255017 0.285610355713034 0.0542776743801825 0.12771242863518 0.124596965105973 0.0286283332224325 0.0271184961847346 -0.0828215743745639 -0.18077389452453 0.0409819756335348 -0.175896233031903 moxonidine -0.130706892748392 -0.552152192203821 0.128080045325969 -0.366315305970799 -0.494813937182671 -0.421879351856171 -0.308510232625307 -0.34301603196089 -0.397090785174888 -0.413053652728182 -0.379096435465829 -0.368115633765745 -0.545791209030117 -0.439885057291926 -0.578621888790809 -0.433177335073752 -0.233275695612286 -0.492298925596988 -0.592315332752436 -0.0692705492111029 -0.518910743826499 oxamniquine 0.0236358863816127 0.0373892074704226 0.113303036454217 0.0661430489827126 0.10818056133271 -0.0167885335346972 0.0257720443540773 0.154993879775244 0.13892862436513 0.100275658118178 0.0588373746427292 0.126347694746938 0.136346276170785 0.131007246569051 0.143227910228582 0.142511035401103 0.128091870194173 0.161542346455132 0.0744940561290527 0.183783761048463 0.160367515829928 Prestwick-967 0.156151978340385 0.300607188455919 -0.0100885018536542 0.345895149661538 0.271792791663626 0.0507381158395763 0.00652414339529936 0.354579641780784 -0.118151784187934 0.274581690016493 0.191531099541603 0.109298253708678 0.273744725074065 0.282907223412064 0.304412989465836 0.288654450821018 0.156710362205438 0.228658457720262 0.152166488503119 -0.100830447109251 0.391398577262176 zardaverine 0.0249345990682192 0.223248817446215 -0.184321516569564 -0.13306134338805 0.274143662606776 0.472710965277221 0.232008543951542 0.305650469881148 0.195557847895985 0.14490274221693 0.0498526328114919 0.282167877784806 0.251687192899934 0.233065298325324 0.238331332711779 0.197722371524652 -0.0529915193319553 0.101619319640861 -0.0953004229140114 -0.0133875631832107 0.237365866638793 sanguinarine -0.566202571351872 -0.791700902882405 0.395134046360584 -0.618241256030164 -0.69611469246136 -0.466338575074369 -0.263476881977401 -0.694874719694575 -0.747366195465675 -0.687100458276595 -0.596706835734532 -0.664586570042996 -0.791293130327685 -0.811594428891643 -0.697484240445692 -0.742276340949873 -0.329669616407044 -0.725347640329361 -0.809982529624579 0 -0.723239591771459 fluticasone -0.122485698177871 0.158115712695547 -0.232928056693879 0.243526506655969 0.134313169529718 0.0629528695568813 -0.272653587944667 0.248832662148854 0.147046714936936 0.0786845074008627 -0.0151783846566038 0.0819465426706851 0.185509528416524 0.223172470501523 0.223830535515275 0.306541705154182 0.0520884698594218 0.247382290817939 0.296208788023888 0.148416223437889 0.12771184514985 fursultiamine -0.110321014695555 -0.0970063299561662 0.347603171672109 -0.1559217183282 -0.00146289744432147 0 -0.355816659239016 -0.0608851713203427 -0.137159192690332 0.0129217746032085 -0.0936274023210683 0.0178689998903921 -0.0985837508007319 -0.12155147552219 -0.234023479581052 0.0444614662775757 -0.169465740975142 0.0616982751210379 -0.114694369575421 0.166098818600501 -0.113753625602418 etilefrine -0.0548284339031543 0.175777795371654 0.299227256764857 0.208944173796599 0.279236252871919 0.419267898545372 0.0450335709413247 0.334444019680766 0.26532983441188 0.260234882819151 0.0748092120985622 0.205182652616383 0.166593388901606 0.305407102066242 0.238820442702695 0.196558179456661 0.143705117591397 0.276134988077273 0.207423528776157 0.0469072997134675 0.147738934004773 tocainide 0 0.44065913611005 0.124824723735199 0.585876754748828 0.21630999710396 0.111621211514717 0.00598996062380401 0.289444999427865 0.234757025280957 0.360453820153456 0.348919211844387 0.345829509593782 0.403213882372337 0.402647812397158 0.278582115600258 0.245791952238581 0.441743898749533 0.491704222914632 0.415165310989343 0.0988880917700445 0.471441857399352 zalcitabine -0.124624885515976 0.0749014827684491 -0.107817218277711 -0.045144777794196 0.143883877923138 0.347421218825793 0.0570080940606715 0.10648676567014 0.0685366514490209 0.0593391709634142 -0.0884355841119413 0.0533452091210113 0.0673138894765005 0.00315856570094344 0.0311713886456315 0.0671849705707635 -0.0758400076907193 0.0884529069871196 0.00722568992121184 -0.00477987633416257 -0.00552666593439508 decamethonium bromide 0 0.0821571629350797 -0.286592082779045 0.188550822625587 0.10051708680068 -0.0431759648350746 -0.261044671404235 0.0888432649305406 0.132274674306912 -0.137097045344274 -0.00300282275622331 -0.0444895018170713 0.0254760726992653 -0.0672547381794255 -0.0566470605396147 0.0664681682000858 -0.000422817921947705 0.0873936939139817 0.012710610006885 0.350896008861126 -0.0735893921547222 memantine 0 0.265455921355191 0.165343562871841 0.334493770604866 0.101891103347915 0.123603416807916 -0.080567611518393 0.205949488382319 0.19033683252998 0.138221672091014 0.111802831149262 0.156609618819356 0.271044857770789 0.274429865734201 0.296439558531727 0.274951459729471 -0.0253348566005502 0.296270263372334 0.254391094672905 0.275211147524082 0.107910301691715 harpagoside 0.082464774376005 0.322655204503672 -0.0514999052418481 0.0588059933817602 0.404187598227955 0.316673125607171 -0.0664887685864538 0.261205667677766 0.350743077579084 0.228890529530604 0.151551885851042 0.129046525002845 0.336386115448094 0.325792413998609 0.350188757561557 0.34910554028829 0.362838586912592 0.342199174168215 0.360862703621216 0.251627162759532 0.304315521559134 zuclopenthixol -0.18895499657026 0.115891477067199 0.259788545644775 0.208799187307064 0.098441409981203 0.000850801813340685 -0.302809912250697 -0.0770622377204438 -0.0278029369735713 0.0195245353462106 -0.172359757299129 -0.211601559047092 0.0431310878797289 0.0578610442878155 -0.147939337513289 0.0858829373509404 0.0554649765458366 0.0462910333656406 0.185348604564614 -0.00280955946451195 -0.0633834065985745 gabexate 0.171513999009903 0.457184333388139 -0.4249704123166 0.444905229291726 0.403069706155954 0.272783894942861 0.0958242258488278 0.48426063393045 0.308170593884195 0.26436937734124 0.318582920575776 0.219517667410909 0.28351730691596 0.448927198720563 0.372010199773013 0.547254914779253 0.437629581900678 0.575369626748701 0.32462781500609 0.247382434462676 0.145620001759407 alprostadil -0.226028895642774 0.480191049876012 0.0766073146481374 0.393532037278916 0.277358768302368 -0.148839546926673 -0.162422059713123 0.382038315073937 0.321688467073112 0.372249152085331 0.189576552788122 0.250011757329434 0.431675618311831 0.543265753184258 0.544627643871507 0.419159915036182 0.357655920156091 0.477882928486902 0.460595036942194 0.120541533016553 0.32766673659268 benzathine benzylpenicillin -0.0811913957940822 0.400279685764358 -0.101829751269593 0.378906497048621 0.392298863357548 0.0810438096188795 -0.0975813018350742 0.448676589532632 0.325478873322396 0.253967385177723 0.153045849565651 0.349957169998551 0.426613626188826 0.416710860062769 0.434320976415771 0.392480119832691 0.24244560350924 0.494069051585922 0.440365636558681 0.0824879308990848 0.303621806822198 methyldopate 0 0.430958810773452 -0.40437933487257 0.447562616906724 0.429107067910002 0.158682348585545 0.0374111645184994 0.46437873358561 0.327020007366351 0.39538029437927 0.221306047807205 0.356717955032148 0.445545650951429 0.395349349358098 0.449337943265253 0.414848505769728 0.362072367867667 0.442094013349773 0.414023582635779 0.328628297905319 0.141069311985594 3-acetamidocoumarin 0.29782256901682 0.683428399582327 0.0857184240632471 0.607212967917188 0.530319714150052 0.38385634200884 0.113814633204255 0.634793675156202 0.447492365242487 0.638568680687144 0.454002760169968 0.662881988675827 0.701313265988881 0.684679605930936 0.660328653315128 0.661262673788164 0.469089142794029 0.646503697826792 0.666970641547241 0.419539912667373 0.524973353118178 ozagrel -0.157666386888152 -0.269292037736681 0.135372626007751 -0.271103208311877 -0.182788844626708 0 0.141047056564067 -0.244250437143597 -0.0415938498894281 -0.220727654069715 -0.190625501238812 -0.197001171914998 -0.156240461189393 -0.174643909345248 -0.212882555437685 -0.143925875232018 -0.0547416442545453 -0.284783655495264 -0.27249117405261 -0.327369241549282 -0.113681759556133 asiaticoside -0.14624644292508 -0.165751095271363 -0.0101069983445723 -0.0603611532589667 -0.0322031966574187 0 0.207481274580877 -0.13268812752586 -0.00550530802489188 -0.258884437405684 0.0748618917267237 -0.00384612528515249 -0.168632036920158 -0.169379757301488 -0.0185923289930207 -0.0249706917143673 0.00693447637823053 -0.110019707973982 -0.17107827171453 -0.191400573614805 -0.200216254406247 proguanil 0.0415196737207904 -0.111527018899485 -0.359556514013915 -0.19349831277192 -0.0114318579828379 0 0.0602233307465579 -0.0136634798608691 0.00586673892006342 -0.125264352613645 -0.00565123706839565 -0.101951202491684 0.0180824256889246 -0.143471026117361 -0.133233070244331 -0.120756211577104 -0.122784992740389 -0.194407292724766 -0.0931545217027977 -0.214311614821623 0.0488794461487381 pivampicillin 0.0952669592309488 -0.391989890336798 0.0831480122671975 -0.445201801848643 -0.232287225569541 0.154767908007595 0.00578333032309358 -0.356721003859265 -0.433213484256689 -0.4829896775757 -0.348279940457084 -0.324889068385174 -0.411105725906615 -0.438490015195847 -0.376845700976247 -0.421295406496059 -0.213577520417897 -0.442742465219747 -0.577996324644973 -0.405331325839412 -0.599105617683588 tribenoside -0.124788939424519 -0.0459536066779031 -0.232216463676387 -0.239716690311746 -0.213806219290109 -0.261535785704571 -0.201084175863925 -0.169063126014437 -0.101686763515884 -0.0355570169948669 -0.227265580642985 -0.158484803007875 -0.297888444280064 -0.233578482115168 -0.197934734358612 -0.0918343002302545 -0.1482455342401 -0.197881255630617 0.128849047770236 0.00725871939092906 -0.191770984486204 risperidone -0.259003128419216 -0.185447186043955 0.164621466602683 -0.119339670549586 -0.195622695329168 0.235942994043937 0 -0.213148756301516 -0.310051205820659 -0.24061303172155 -0.172292092843137 -0.224723946919309 -0.193954582201869 -0.241323635635555 -0.297685439221938 -0.240374741544945 -0.191053601135075 -0.17686368878344 -0.287009466309871 -0.00105426518327978 -0.22642668542764 levocabastine 0.192177048638938 -0.37238574084869 -0.0244751404714581 -0.287471066995498 -0.324881296387396 0.141389016291303 0.0561906601719775 -0.340754714883665 -0.315735472296252 -0.406908093462827 -0.260203186697267 -0.291574061726188 -0.372253337053945 -0.393584915844597 -0.388853220594482 -0.325864292150376 -0.316479526049607 -0.349730910828752 -0.381381843506509 -0.291196138535732 -0.342840922489208 roxarsone 0.112784764537887 -0.586744314724825 0.0418233046064067 -0.493494404223042 -0.525020143173526 -0.223484961336089 -0.357802351476151 -0.544946223970829 -0.480871764500718 -0.597516611132253 -0.420235701966556 -0.540710729437945 -0.521591888357271 -0.545984292668015 -0.61765811481622 -0.602779389704582 -0.495259109015201 -0.453080135489114 -0.656836072773975 -0.0469901515840034 -0.429147641946382 piribedil -0.163664299086802 -0.390318374354112 -0.130488231546669 -0.349918690474252 -0.22286952847044 -0.335166011176747 -0.178236489187051 -0.507538387900157 -0.377107720210799 -0.413093702096781 -0.347578950464651 -0.369945603161257 -0.432881802355229 -0.455423925387943 -0.408245802451253 -0.415344756448 -0.468709224691974 -0.370913048766514 -0.410195652540773 -0.416837418422517 -0.388007472401608 betulin -0.0752386285636649 0.224844404233395 0.1564463314564 0.195097947941195 0.178526879075084 -0.249091359865034 0.24107918977219 -0.0541084721016191 0.0631721410641871 0.253330348105615 0.217142026024461 0.0502270041489511 0.229422299046641 0.220383977636564 0.201133540444169 0.199129931397964 0.0660573488385368 0.174419971399017 0.240949035653743 0 0.0517664746538132 lymecycline -0.0197755000285113 -0.492582288862123 -0.0368226737294971 -0.279806596791884 -0.457593477371085 0 0.0179684446478572 -0.380669889397419 -0.274739316423758 -0.490015291569757 -0.408482047070292 -0.467782413562824 -0.529266069803504 -0.549621075418559 -0.563603659396368 -0.50702020683665 -0.160280275880928 -0.480703812240627 -0.415168241715606 -0.238372075000116 -0.478711910625854 talampicillin 0.144993380131881 -0.662442744366494 0.134561996954972 -0.483301213580476 -0.523857705256902 0 -0.27702982084109 -0.671072836875231 -0.515550191740063 -0.645310012362691 -0.423814218591035 -0.602198200309489 -0.687880776667131 -0.735695930700219 -0.751698848505913 -0.66230709152766 -0.549179457052643 -0.552511543569738 -0.76374889829012 -0.442541843339056 -0.64198291519031 rimexolone -0.191461976351907 -0.670023155729144 0.200441191101399 -0.529982928459903 -0.6535247570939 -0.359534178727013 -0.408991254425606 -0.689319616109857 -0.49735118059029 -0.649288219178762 -0.530185769073706 -0.654815688728843 -0.716391740078284 -0.72012759975766 -0.706867255901767 -0.675870150898413 -0.563808972742449 -0.655378456911523 -0.703962103691136 -0.435255266991185 -0.617394224451126 torasemide 0 -0.489805614449498 0.142335020708522 -0.440780044807518 -0.39501431389764 0 -0.318474793860864 -0.411793666878173 -0.412461453199616 -0.509324052138788 -0.26649545325684 -0.42774455516559 -0.594389042292597 -0.506528026385034 -0.522391588501529 -0.484526473661383 -0.314174562142146 -0.46137191396793 -0.644602416568836 -0.406765053538795 -0.454073108008187 etomidate -0.216251089499265 -0.62414414651427 0.501537886311943 -0.423926003217145 -0.616520140485907 0 -0.514335537199632 -0.671686817653372 -0.554534337376065 -0.648745907788373 -0.488668635827656 -0.548079360502589 -0.66554752858635 -0.697857268277747 -0.719964164262754 -0.681562362076759 -0.337716613979832 -0.662688394225489 -0.698926624135424 -0.160318192386589 -0.577449632430077 moracizine -0.152950405484666 0.0142145797263727 0.102641188695318 0.0310920254785606 -0.125903107721091 -0.1553362006264 -0.346660473830111 -0.0623998076056152 0.251124997608517 -0.101691404313047 -0.112389889945358 -0.128364715732257 -0.00757721512845552 0.218435533053348 -0.0410762272752928 0.101871300656736 0.110737562271166 -0.0129239891075331 -0.00151573833619473 -0.0336535352744945 -0.128953389781233 phensuximide -0.190052345024443 -0.26810941603525 -0.145110335287074 -0.143610854273071 -0.307140545071587 -0.160414540933717 -0.147235837967807 -0.253628216095646 -0.235813450465383 -0.261306864377062 0.0522296889642818 -0.259625320661806 -0.151465260753216 -0.299760487140229 -0.0374024902681341 -0.275392436312422 0.0361352842227672 -0.171002137549691 -0.124728641880121 -0.22723602409987 -0.348241461193395 S-propranolol -0.109859477301197 -0.297709003388614 0.0662588525993517 -0.323062279796108 -0.320098960219992 -0.0831706997622167 -0.119246749026151 -0.362255549719491 -0.282437697934039 -0.402039383660047 -0.310204730270991 -0.338610062037287 -0.343848575879549 -0.387397079219047 -0.359322140488839 -0.360887274686188 -0.37071462323499 -0.353297079930105 -0.387977382638554 -0.457934286881346 -0.558772334450926 spaglumic acid -0.0464848840983925 0.310136856628138 0.395580126006042 0.496498898087232 -0.213069564861118 0 0 0.100431186054537 -0.281708569523314 0.087739673475291 0.216713353170845 0.133979462305184 0.319471885952447 0.358593148145404 0.0640817742448093 0.283937175071279 0.325977869907194 0.317778721007747 0.0808072687438423 0.552093429922889 0 netilmicin 0.0596704265286076 0.243559303344336 -0.232378365079702 0.220082871937819 0.165591289038936 0.00366902610570607 -0.0586675615314867 0.160302329026478 0.202116659075461 0.190994835163624 0.184233018420629 0.184258249662243 0.224151438847754 0.20601845401247 0.163761603942306 0.240216450762922 0.249392342445842 0.351445481996079 0.361945999508588 0.247956992995929 -0.00669063299681455 tridihexethyl 0.13230288366116 -0.103207672400771 0.200550419507735 -0.114554048621823 -0.130362728591908 0.162435371594178 -0.180401676866629 -0.244836607093153 0.0403330193127493 0.011351781756037 0.00662969952619399 -0.219110766741001 -0.356336030534576 -0.242052640764342 -0.202097778484579 -0.240485563736253 0.126855986162587 -0.00822756408130705 -0.153870669120485 0.0394185804542047 -0.221268104165491 iopanoic acid 0.129981968228029 -0.11322066183966 -0.163985292215271 -0.165011895218686 0.00586112326255764 0.161467230401065 0.00764774092399009 -0.0201935923339249 -0.127713043374021 -0.21919389535304 -0.218586303534927 -0.0825542682814933 -0.0663903315245363 -0.11195559109253 -0.106602539319278 -0.133442510248943 -0.135709889375609 -0.120083161210344 -0.250238972809752 -0.235256354289419 -0.0122079998262808 ioxaglic acid -0.0221152565313709 -0.0827704291727681 0.276074669709785 0.421205717287094 -0.333330480995388 0.379263283406281 -0.0998481643972178 -0.168285141936533 -0.0242106953221518 -0.14657558058906 -0.296468612171045 -0.119503320421565 -0.120632054974229 -0.114668271857118 -0.142581442373029 -0.0985450669241176 0.0528639675879775 -0.104953004069134 0.00426081981830255 0.116437793450129 -0.0409799268179336 lansoprazole 0.178221639932126 0.399729642927054 0.0967317791455092 0.385807162267754 0.336561259706976 0.0731238137479717 0.142759238561128 0.301388251690538 0.345566057803301 0.350243702078428 0.255580754953715 0.333800193977192 0.339204560493119 0.34490617051137 0.313093628455765 0.356095056159677 0.424691829507221 0.40498179207857 0.346573980655417 0.322860120482359 0.318791824275526 cyclic adenosine monophosphate 0.473788588872419 0.438718592609018 -0.0206867611104588 0.160728039241448 0.284247688967429 -0.108050494478345 0.291638489109331 0.265738555567672 0.499249317939745 0.320572019536951 0.332649788476004 0.313600280142386 0.352104553919528 0.486396025658063 0.231516823527901 0.312061453869809 0.221319801870297 0.307419102550617 0.327431811468925 0.131282521641767 0.128336766331606 loracarbef 0.254405537154514 0.150091458122804 -0.346211385293074 0.146524302363063 0.278851846765834 0.12603430037249 0.49072137639152 0.00956257231244897 0.216425939579312 0.185900341322101 0.0951712025338077 0.135559181067395 0.174941807033191 0.143022380087493 0.158703182179344 0.169885352168381 0.298332941704209 0.0519228408988447 0.0530227038060559 0.091788796989531 -0.0288988695542334 procarbazine -0.161378292914512 -0.0418141760655459 -0.308598443579607 -0.197466835701444 -0.186918651163245 -0.233891883035626 -0.124749948912928 -0.383879976250053 -0.023395931403038 0.0170031780068528 -0.0890816511582004 -0.112020251789241 -0.154759280111027 -0.0444022879178504 -0.147267965012598 -0.159847037218365 -0.119466809206793 -0.270963541130854 0.165634426778783 -0.310644973619338 -0.143622055073377 penbutolol -0.054116014896449 0.612365927142808 0.445179338593992 0.599493187367918 0.3915277220825 -0.203917283714274 0.0966581366868379 0.193788649784229 0.463051602679034 0.427940146103985 0.00120810157966069 0.361432531953859 0.398764156229983 0.436065257379791 0.207752788261047 0.236703156418735 0.246523591015327 0.207409445226107 0.490042041295769 0.165961625461492 0.412500917779448 pivmecillinam 0.12850195389883 0.377778274214946 -0.184022235536423 0.489042309007595 0.220645826087218 -0.207483929238371 0.198952328872962 0.307683853372815 0.347209347282199 0.310862238379638 0.321185558588258 0.380293417603844 0.475909963986641 0.371845952096113 0.350001990957979 0.621587289560164 0.523113576768265 0.492099635789691 0.21855482951499 0.446512646582271 0.563536442754737 naftifine -0.0630977919575682 0.0315952305497379 -0.185228715412503 0.0154911942627338 0.18949652386002 -0.0283186712818433 -0.134069745900474 -0.102237031511988 -0.0222446710768127 0.0310970398793491 -0.0300029602252574 0.0461580515389374 -0.0661320572218327 0.0250816400692825 -0.119529010855171 0.177695596977228 -0.0509048422916686 -0.0915149193837949 0.00991150333266096 0.0270402340020251 0.0286955609323181 bethanechol 0.0176648272994001 0.0911275429525371 -0.142151016941439 0.0912475761230268 0.0732482459279604 0.271109260460207 0.237223087557382 0.0780893861752322 -0.0128097271329128 0.0580500744013222 0.0194397910279133 0.0713523104113093 0.0692376243249968 0.0165794276370982 0.0238204033096461 0.0414402717664526 -0.0917644093352833 0.0586680015656919 0.0473286570743221 0.123975696698297 0.0325847046696429 Prestwick-1083 0.191324842264408 0.0974863288720459 0.0414356360762752 -0.155113635161728 0.174560620000663 0.377607632894536 -0.204846795928361 0.182756919187503 0.0394974129039714 -0.0790097963157139 -0.12419198562396 0.119530543329544 0.104224706455785 0.0593024352865092 0.0814601239950505 0.048590504829535 -0.346720698377382 0.0553602211836638 -0.109136887410191 -0.0605398517509776 0.139072341208704 Prestwick-1103 0.148587093020408 0.605437415429962 -0.42667401204371 0.620317236834931 0.459152254538765 0.152149721795038 0.114135160083787 0.581295069043296 0.54471914143588 0.621050151252964 0.362278298944136 0.356977690022714 0.63980415095511 0.646335147086508 0.637301981622394 0.642390791368681 0.47131361147056 0.636136511431809 0.677794206474328 0.134872995519784 0.571264041739044 viomycin 0.0829975683912577 0.727921820179207 -0.26684767005071 0.670183051082705 0.675268782367498 0.136259480187354 0.171888460501548 0.70359906042533 0.683991516060488 0.729309436203096 0.567279950844751 0.680853639692502 0.794896512062242 0.76691763038603 0.788706285727161 0.767508732432229 0.679672523408732 0.700514388111963 0.823121100161205 0.414581217875162 0.299439315266405 levopropoxyphene 0 0.404078539456112 0.114806359231987 0.338429055748461 0.418627724862428 0.363793004953203 0.0637207877527051 0.390607554895331 0.410953385603726 0.427467142866215 0.157056215140155 0.367770004631821 0.44288816664778 0.397400799990633 0.381269188603945 0.39559295422176 0.384123669698001 0.380942884099877 0.430618757018615 0.0230543090535641 0.406512920489539 nafcillin 0.154702042489086 0.0810740345068837 0.325414767184044 -0.172840790638663 -0.0481946227947829 0.198116402840073 0.0830187217935373 0.0485337572506177 0.0412770779655747 -0.018469117845372 0.130990117818821 0.129471705951057 0.08075369403458 -0.153407953431098 -0.0108034194316982 -0.029751736288547 -0.0757712820742252 -0.0457373879568456 -0.0443677199406214 -0.0226526684589601 0.228596488184884 liothyronine 0 -0.604681862534592 -0.0932823749710571 -0.585471327274331 -0.614825690360947 0 -0.136276517963646 -0.679910543836399 -0.491001617573318 -0.601165839381823 -0.201734297759725 -0.492500443577024 -0.617805490663881 -0.679818511453435 -0.530554257672958 -0.657686024151316 -0.505107942709896 -0.63631045790812 -0.741602561962531 -0.3236705503959 -0.414920961989808 etidronic acid 0.0223921892832752 -0.290700341739524 -0.000703830638571351 -0.179752899681283 -0.344977398949829 -0.103113553844684 0.0906762791164938 -0.353785296744609 -0.0925000103705076 -0.330089763282192 -0.148820820982869 -0.0984346440427102 -0.310676617068598 -0.298183917599622 -0.32521111577686 -0.258601100972025 -0.104829010723767 -0.289635061566953 -0.365962179764172 0.0305239430417839 0.0796505226908245 theophylline -0.201517495777065 -0.0273182249325586 -0.138172237073952 0.0210109083735411 -0.146015940818127 -0.311781408894904 0.049815529545008 -0.0905342901723977 0.0691670934594539 -0.0202807819660104 0.152578982842378 -0.00480229440083066 0.00926194033578878 -0.030548092972597 -0.0603819252294291 -0.0367639986179123 0.152146286874335 -0.127040605636085 0.0186832059440214 0.0345181952872296 -0.1535182284056 spectinomycin -0.0187710773182778 -0.239999586048348 -0.143073297138811 -0.312193430968267 -0.147172175132008 0.0610334967843994 -0.162731347989797 -0.274886883865606 -0.0146005293362748 -0.329850392055129 -0.139036973892634 -0.117700877010832 -0.376088071366559 -0.236999251553181 -0.250182715763008 -0.158886864567607 -0.211441454340146 -0.360613393790765 -0.520495243278369 -0.196660502412148 -0.174806720408801 cefsulodin 0.0966808214232696 -0.327137293808279 0.110811215694976 -0.324746054263699 -0.447866382649771 0.105495706582771 0.00836895638654367 -0.374139441870233 -0.1682106839464 -0.358456053467825 -0.0862475639234699 -0.382628513192755 -0.294087622261855 -0.36373756028096 -0.320898872625876 -0.413299323444044 -0.359011160855554 -0.233198198547853 -0.349875578402702 -0.244945373035123 -0.220653894523317 benzthiazide 0 -0.30851183142892 -0.129300022802364 -0.334248696994466 -0.343740576478301 0.0758271616508988 0.164682267755385 -0.382143321928817 -0.170653837967264 -0.188982477538794 -0.153264196865496 -0.20855192165646 -0.311219709751643 -0.392067553466475 -0.356355211326408 -0.336946915019688 -0.221245360354569 -0.314888627160553 -0.346413970715764 -0.394208303449928 -0.27435905612142 procyclidine -0.366688700981128 -0.296038785222545 0.183855057652784 -0.0547268568451166 -0.380845638365303 -0.162026760736402 -0.302248719645693 -0.36746585600831 -0.223516239817888 -0.196244413347527 -0.18595450205406 -0.349079113957092 -0.328372360390469 -0.321989597950272 -0.368136542249817 -0.313452218464236 -0.0812527377356186 -0.174132579704539 -0.0587039159887622 -0.15538737475256 -0.019591274199145 roxithromycin -0.394575547853522 -0.605554396090415 0.2633240992046 -0.412174534233585 -0.668070944192479 -0.175196421574628 -0.27896985085897 -0.623072931188311 -0.496885661985167 -0.536457617415777 -0.339503399160529 -0.468779033791483 -0.628721201752215 -0.653080478136593 -0.657936000400086 -0.624774260918422 -0.420497426278328 -0.495011279482864 -0.559412288034558 -0.35980786370171 -0.351310901016722 Prestwick-864 0 -0.062794714658878 0.189133043445217 -0.119077951500187 -0.0919605591066221 -0.215532876084868 0.17717928470168 -0.131919560084655 -0.0010358379859013 -0.117610119673786 -0.0241097689449169 -0.0677249249505504 -0.0752227965335862 -0.065793657766387 -0.108801879769663 -0.0466620347501323 0.00275717816104513 -0.0990927663277577 -0.0689713067218836 0 -0.156786527295303 theobromine 0.15619688763532 -0.236437398864463 -0.199261508039449 -0.138899507538684 -0.0954338402668524 -0.269721537225981 0.100375823363498 -0.1169985725586 0.0970786560761196 -0.0507692267817866 -0.0131674504029381 0.0171432491625668 -0.0736441259599432 -0.0917088709026827 -0.0756965590229318 -0.200729822814775 -0.0289638928389482 -0.0865082851347845 -0.113730787693564 -0.0669293932933129 0.00765883221903538 piromidic acid 0 -0.497625919645746 0.236193586726686 -0.294438835146005 -0.456400919506628 -0.270378866278412 0.0411066406835587 -0.258744821711361 -0.427869708915169 -0.340822878547014 -0.352696237207439 -0.303659154234771 -0.358147717509131 -0.412217025179238 -0.404328606102216 -0.458480516084251 -0.357719951719137 -0.362041223701407 -0.416664434592471 0.0391729422520858 -0.296006387050605 fosfosal 0.220775057640428 -0.109717237929069 0.089927632361627 -0.0843171347533203 -0.225193822234879 0 0.0106452784382966 -0.2366060922914 -0.363609129880135 -0.272709552890296 -0.132159035312804 -0.350810844750599 -0.11332757753444 -0.155878419993905 -0.292878146966092 -0.146031432392586 -0.336929216763374 -0.330535805123279 -0.311046875967233 -0.0285660871663934 0.0399774900537389 trichlormethiazide -0.332814037812914 -0.315735009371704 0.134107133206906 -0.158417428149096 -0.318368094758584 -0.40891083345677 -0.250088184740649 -0.224250450133488 -0.311221997684576 -0.463857024620834 -0.350659346217902 -0.268622788123095 -0.291061888211434 -0.439661214807912 -0.349433030847596 -0.408586942168236 -0.288506110093786 -0.45216451068782 -0.457199999538768 -0.224371502896654 -0.0852085777202653 tetroquinone 0 -0.313488444631168 0 -0.241514313083664 -0.284707576841115 -0.0108465669228117 -0.132173609781971 -0.39689898103831 -0.308099257394104 -0.385486855772436 -0.0719876129339485 -0.262587900878153 -0.325284327695652 -0.379898946771744 -0.507863220499374 -0.313711448182745 -0.0346787690770394 -0.313727304597847 -0.334994239457395 -0.206166497785024 -0.00156464635925363 amiprilose 0.1707958408176 0.0820039922237736 -0.128845764160776 -0.122804396888028 -0.00284992456236016 -0.0374035391268259 0.30344447817182 0.0802146003129481 0.0774437176759549 0.0370161051478511 0.26590014562773 0.257202291261629 0.0962878655627066 -0.0243921429468681 0.0958043066272208 -0.0178257110929354 0.0146506928733326 0.0618686014319196 -0.178261215042886 0.0346535938720173 -0.142271141784183 beclometasone -0.300696796827174 -0.180821976702494 0.00412797322976014 -0.141054885022123 -0.14669683031293 -0.0231067825795317 -0.396313809164343 -0.219705599126911 -0.278290080087117 -0.252004268478101 -0.188058455438135 -0.219832287736127 -0.199178669231673 -0.267377883028376 -0.250779245267432 -0.200758458731903 -0.34723083831115 -0.184489585959971 -0.276796855106728 -0.32204488683102 -0.156384745603019 simvastatin -0.637131862782298 -0.381612619950898 -0.33661846243749 -0.292092510601928 -0.483670493989534 -0.282485254968915 -0.570037735336688 -0.465008716163911 -0.402931552543339 -0.563421301986595 -0.35694531136031 -0.440262341763435 -0.570122151711249 -0.536652919421229 -0.592477271008029 -0.503555571271884 -0.323111449917057 -0.423172698199638 -0.41828383190894 -0.417012074153389 -0.454167663589813 reserpine -0.514147804540335 -0.595406173647994 0.367481341261177 -0.330320189323954 -0.620162590612275 -0.114756469687122 -0.416700005988976 -0.511275730440724 -0.479389215348943 -0.506429666048768 -0.37126923922429 -0.471967914929219 -0.598916000648995 -0.638080541087894 -0.543614159759234 -0.594163318092703 -0.520735651047094 -0.507805115416604 -0.694239729800691 -0.375317558995817 -0.482301120049543 trimipramine -0.341287291994097 -0.369710962906577 0.251402592035912 -0.333026562808672 -0.368956886287004 -0.141161760457958 -0.31683098999889 -0.426971358809956 -0.299027645594816 -0.394015394922829 -0.265746538062246 -0.35514800249099 -0.399616158249162 -0.347483551498781 -0.422970029297529 -0.326978776439356 -0.24663072776038 -0.398206058072209 -0.331843619470711 -0.411203516290402 -0.0820775869743335 suprofen 0.216844888014253 0.143103340398458 0.0238127250366646 -0.0461592102135566 0.139135735128539 0.174468883205686 0.0119239836320823 0.153496421904988 0.223521177878823 0.0206788926781439 0.0453595734173447 0.175093798071389 0.199765360072859 0.150241443703898 0.0497000953644991 0.146095599740894 0.13300138697753 0.058463051645056 -0.0793419867272055 -0.096149718138012 0.151064324557978 oxolamine 0.135793706122611 0.433042274107312 -0.127898762117795 0.39569350063962 0.24350174533657 0.0538708777160641 0.279104170272415 0.253747987591473 0.255360757510099 0.329756782242103 0.175117380197913 0.348351666702255 0.320138394337821 0.294309605824684 0.264667591440333 0.327840499959444 0.400104353228757 0.297745354210461 0.30814606502224 0.251135968586411 0.370196605483564 indoprofen 0.454868762958597 0.457477264002384 -0.318866775570267 0.336760580574151 0.409208678299848 -0.093228536489989 0.128223689036186 0.302586961893573 0.410959161571228 0.415385419242156 0.342187108142923 0.482700379797536 0.569818125071494 0.458664234609276 0.183217204408035 0.461520898407177 0.577189100547383 0.529134678415564 0.43945832551298 0.319012900715131 0.149318375320778 mestranol -0.272873963243327 -0.207857692691072 0.110813745898445 -0.00274513397299636 -0.346003454640239 -0.172365491175164 -0.25223571586233 -0.17988169239776 -0.297812353202951 -0.295473449460081 -0.18487155314731 -0.243958553580726 -0.286559906767287 -0.256490351522652 -0.263729101021983 -0.23442570554145 0.00336823083234841 -0.100653713824835 -0.227257970211446 -0.171254418931361 -0.168823063006347 tolmetin 0 -0.0183609537717756 0.0426778500748631 -0.00601268957584415 -0.066186229599334 -0.159358428311931 -0.183010441101916 -0.0783474380393682 0.0418116513362952 -0.0548960554197485 -0.0368910122307507 -0.0678651572618564 -0.074521265066447 -0.0541436262933023 -0.0609581245230893 0.0146101893489295 0.0648274872848354 0.0306615305129659 0.0168616920620246 -0.106938728550247 -0.0290283510061014 arcaine 0.179331996991198 0.256351621238931 0 0.204734573262133 0.370554475075507 0 -0.00894261863315014 0.345052207724999 0.179398220550141 0.221922641624873 0.0615898226158692 0.242070102234993 0.352967467686507 0.253968610361803 0.307853895927017 0.27152299450597 0.146163333693977 0.150768411827206 0.151398589068073 0.0481027348495502 -0.0438580676890209 chloropyramine -0.393389872099815 -0.253924807609876 0.404788395742155 -0.16783786957276 -0.305006821595257 -0.607949627954315 -0.287067326278052 -0.365745463684616 -0.22858888265357 -0.318895073621822 -0.15160457524711 -0.297507732267911 -0.299440579388761 -0.278589643910588 -0.042526808609306 -0.262879449191994 -0.246022764626965 -0.307369022380257 -0.0144243473655822 -0.330171307086783 -0.241835450077306 (+/-)-catechin -0.124785356355155 0.172795209019502 -0.150195671527945 0.224145277084248 0.0319368075110866 0 -0.0551285205644192 0.188328508015302 -0.00352225025348277 0.20183862557523 0.160536414432138 0.132975287475667 0.178766847947221 0.0482380361600071 0.196757532680582 0.0610792570796531 0.121867114072807 -0.0617858381629938 0.129306426693404 -0.0387822444160214 0.070718793591553 propantheline bromide -0.24582136404375 -0.201930453459888 0.117047164711281 -0.130201125697236 -0.289884067361602 0.166564186263468 -0.123231672063443 -0.137556270158006 -0.182525720219756 -0.174535972393 -0.104192613552223 -0.178912197533518 -0.287624346433107 -0.249682615017888 -0.248206011553693 -0.222922048771174 -0.037439613220468 -0.0158211134464323 -0.0702165095239028 0.00998007720616446 -0.188502869339572 carbenoxolone 0.104137222083714 0.229243485697946 -0.164868123044623 0.000234462267091132 0.184824190323925 0.00132235127278824 0.23936680810556 0.101507214574856 0.378971181505876 0.300994180986874 0.217261136332708 0.278236274136748 0.11620966413131 0.314185770412314 0.277461770083054 0.193836398789076 0.261232129659988 0.402305071661467 0.205321317711193 0.0848036158694813 0.216226980858096 levobunolol 0.527748405942896 0.450561081360091 -0.357981600707519 0.353026648737508 0.451471584252744 0.299495978882271 0.25711351538723 0.464717323015344 0.287082847028158 0.512538125826674 0.304837810192879 0.407718915728394 0.544348736153504 0.372422636837171 0.514801760480956 0.56673816186789 0.310457790392777 0.587958445682645 0.352535562776729 0.259974388516466 0.352873027179382 Prestwick-857 0.105844491567906 0.520587561754069 0.0958464466299886 0.471619192592481 0.337744481371348 0.104043666883783 0.420761703018476 0.364054325990184 0.4350660531561 0.240551524363705 0.250545439609084 0.23324533233301 0.449733088688542 0.56399194092564 0.558585295945532 0.421381482189189 0.472794270437458 0.553545379563595 0.136978407694462 0.451333896751855 0.0951981517497308 paromomycin 0.0592708993735654 -0.00604342568742734 -0.0977231610531938 0.103792259679366 -0.0539438724315688 -0.235386040181908 0.257062337425021 -0.045274899060984 0.0278519961820274 -0.0114381535892613 0.067291400229556 -0.012495460313773 0.00159380997704925 0.100673138333637 0.00514154920920955 0.115917038716302 0.232692564034749 0.0127143889602595 0.00323662467919184 0.0953224178411216 0.219064669821959 scopolamine -0.409859186535397 -0.165495385711261 0.20764530099205 -0.165085521737107 -0.412054336254018 -0.224129508515469 -0.0381739254752243 -0.204111067951232 -0.0684474518380537 -0.389079583021895 -0.127401625577058 -0.412230612609894 -0.418884535409148 -0.315958280421721 -0.52149764442598 -0.275068352662908 -0.030434539399059 -0.169637502158146 -0.335888760606566 -0.0734036260256795 -0.0374424936877009 furazolidone 0.0176664398835625 0.264821934327393 -0.487869684487284 0.288690489271832 0.429821723682208 0.280803658649859 0.14871656428754 0.428558287905544 0.257176239062284 0.452793391258709 0.346864295161277 0.519401423583888 0.464634872503803 0.366794475858555 0.223197562865065 0.453612010590607 0.346330175868896 0.475356279158399 0.366861619476572 0.246860083879933 0.421537216036286 nadolol 0.255006742818638 0.678528197670729 0 0.597430867684676 0.705322467555595 0.474394812559817 0.341285864837511 0.675093723543927 0.61065440460978 0.668850401879754 0.386541603634862 0.61422572382288 0.718953769786597 0.707844856342729 0.668279724056408 0.651242137215314 0.456558785867861 0.673204333068288 0.695935210668074 0.247442160931306 0.45214811650924 lasalocid 0 0.575175404360687 -0.0647326391291764 0.597315451786841 0.611997529740674 -0.238156874097156 -0.328814848217776 0.488365125460744 0.281278296296615 0.584405541001406 -0.0949725757533245 0.145552245777364 0.398044623028799 0.533904436313487 0.180339912300417 0.586403802989862 0.121766008832462 0.589188561305202 0.66720466935619 0 0.281054647476501 iocetamic acid 0.0870636647729248 0.257798541645273 0.1958310171628 0.249070562988357 0.236801750687451 0.141123297924398 0.139119270615586 0.0685389429628082 0.275768103644012 0.128459677365149 0.256075673074009 0.0886734632528773 0.282092060968691 0.231619508194738 0.219982823987642 0.233002260253901 0.152845459215901 0.227692004215033 0.300969405827542 0.12323483033198 9.64167157261053e-05 iodixanol 0.225052906543692 0.270991015776691 0.0622536946499364 0.248581275687887 0.216421695878361 0.0602278481736966 0.202831832016001 0.27529633642021 0.253997673530139 0.298254624069676 0.225308152232329 0.221773899786663 0.323474433420486 0.298607386149083 0.299486235897176 0.287639861700702 0.237560062522263 0.284785212883666 0.449466975656915 0.342617915159468 0.257640046585942 doxazosin -0.218900121788994 -0.646012909606406 0.255721028740629 -0.562900478434693 -0.646792629439322 0 -0.1480237758327 -0.668390304351719 -0.588782764845632 -0.676711474377788 -0.474181858017312 -0.578270835980368 -0.692325399288171 -0.69630177341187 -0.678845446732958 -0.650007979594013 -0.531124224185429 -0.657788471001507 -0.752938266167676 -0.233106806962758 -0.566607224836264 paracetamol 0 -0.420151218571376 -0.0830674393785888 -0.190224124519743 -0.257645619086919 0.00601403605117677 0.131824171291528 -0.278604085153822 -0.383492022211149 -0.488320325441375 -0.318903839745655 -0.294641811138784 -0.184786157744451 -0.42965297018096 -0.305350477098091 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-0.533150456389802 -0.105718732738114 -0.387119391990858 -0.561110053710045 -0.57242405811436 -0.598785774126721 -0.517670000280332 -0.643947007582409 -0.633345104888136 -0.658034914503987 -0.6255891865367 -0.62089393340503 -0.405369252209998 -0.602739998767427 -0.642897091360991 -0.345654243952726 -0.607908336374578 dimethadione 0.00841215117843343 -0.246146599726659 0.215590318701029 -0.22004462202329 -0.179209985174312 0.0555878896242269 0.236722805500297 -0.230401139824926 -0.23015167070746 -0.309940273638497 -0.167782985883825 -0.204701661305828 -0.272537496713602 -0.287201589144716 -0.222344156793606 -0.233130182077259 -0.228860475314695 -0.228016651096295 -0.300902224395019 -0.0588736778746135 -0.382748368794258 ganciclovir 0.0466323877536974 -0.304256928368466 0.213402566041852 -0.358078960926605 -0.255705079643044 0.0387619603871005 -0.133977335396068 -0.264487316644875 -0.40052541092642 -0.315120920280119 -0.22997409536423 -0.268717644561124 -0.303394977911241 -0.29806203185225 -0.322132358587389 -0.258035977277875 -0.336394558861911 -0.287405998466076 -0.323047155923595 -0.0730547341825609 -0.230121568211835 rolitetracycline -0.136912105642619 -0.659688444927023 0.117972741783856 -0.443467015431636 -0.61616303012125 -0.15124694360028 -0.364472781347541 -0.603260943327902 -0.462204836754242 -0.544275822448238 -0.19109873497066 -0.496143008872682 -0.660567602513848 -0.572868150867087 -0.651066179895682 -0.563869716237153 -0.399435657162804 -0.624384476584544 -0.549893969183656 -0.182949427448351 -0.535539780949134 fluvastatin -0.329097931288016 -0.172763717705845 0.22185373017872 0.054116812447932 -0.288501717812348 -0.113438945548833 -0.489562470434528 -0.171547107164826 -0.207220308996476 -0.201965803168106 -0.167824365990698 -0.418900874425211 -0.264631221003133 -0.196664449555995 -0.181500332368415 -0.251241348137961 -0.110087564870849 -0.262567448057689 -0.16914043431182 -0.131237071117911 -0.166310258910392 phthalylsulfathiazole -0.280771367057988 -0.696472721232605 0.14315802612249 -0.569824606858367 -0.696586361361343 -0.0739139433468245 -0.204829777037563 -0.723275819603731 -0.625820816844747 -0.698697675612706 -0.524676413381378 -0.630203499071687 -0.751457888302958 -0.737445448687184 -0.729888503835715 -0.702326933322933 -0.411338377467153 -0.660920331353809 -0.759538625548497 -0.283861889251925 -0.655375320186495 capsaicin 0.0981486516618426 -0.407339420121714 0.125508087358729 -0.331603848889004 -0.216791039406677 0.2124339777274 0 -0.399459769466753 -0.497339796660763 -0.331078641547289 -0.370752641686559 -0.370502453801257 -0.286980173709599 -0.462470894157551 -0.469613793179351 -0.296383740383556 -0.0945670835704591 -0.39795068642678 -0.599061519761634 -0.14224986254289 -0.0482069866609584 sulconazole -0.505343863696531 -0.702032248050138 0.227570414607734 -0.58697527810021 -0.673025256095236 0 -0.245898748591403 -0.749635426118968 -0.675426103251144 -0.700494348605311 -0.519718317154501 -0.635133160031072 -0.761726161724011 -0.746549649558814 -0.757648364643437 -0.716291345352977 -0.557622977561771 -0.687193844926778 -0.769588368054849 -0.290702398739599 -0.660289676380102 aminophylline -0.0866475489410522 -0.407596691660741 0.0142549769913007 -0.0295002547753591 -0.28807254497566 -0.089606664713295 -0.0978022932302219 -0.505063279582833 -0.297863552094819 -0.369786822402345 -0.182407293643966 -0.295960413239141 -0.391362861101281 -0.302485800682431 -0.438721294957074 -0.300218750591142 -0.221022701649813 -0.379269114248647 -0.433107121648541 -0.239639175402887 -0.403496136541855 ethaverine -0.349015033334665 -0.603916301211332 0.277795510523526 -0.493121838607546 -0.611949078278995 -0.104087328329985 -0.559595456139334 -0.614582181770903 -0.476486778289431 -0.582871900509027 -0.474514836965303 -0.576632821070371 -0.636909300456448 -0.578225184873046 -0.631050904953452 -0.559565201520958 -0.358152614447322 -0.591530182857181 -0.62447203211314 -0.318229547870012 -0.452886423660269 profenamine -0.386596715059162 -0.178586598750441 0.44847259732356 0.096512940774828 -0.297052842336824 -0.182299455236444 -0.280025579799711 -0.194532209411103 -0.0292358925725787 -0.202559264576892 -0.122815690714635 -0.172722253216954 -0.155038556343807 -0.233127819084769 -0.112523322064348 -0.192883664008576 -0.237067731012212 -0.260694769955804 0.0191621407853853 -0.0319485619821648 -0.126036373820684 equilin -0.0864562711101252 -0.0183086639828495 0.0122647069772859 -0.0146592247442798 -0.084294185277364 0.185935087072318 -0.0644780966709059 -0.218949004923504 -0.197818565157028 -0.245506486861137 -0.296555749838098 -0.0957158986137896 -0.118213567569296 -0.0986917837565979 -0.274803917098386 -0.0730039750798623 0.0467087831461377 -0.102860893330644 -0.100971640266752 -0.228821010222366 -0.193756760148833 Prestwick-860 -0.33115533511278 -0.627763378615448 0.266983919172507 -0.541213152609269 -0.609783688699351 -0.284667830630426 -0.107465983698207 -0.6079235343495 -0.585808252204768 -0.606114081790721 -0.414761954160256 -0.510837921657025 -0.614359914717948 -0.659326799087093 -0.621934877358666 -0.63532187465386 -0.496433895243256 -0.627478537235362 -0.672986748060467 -0.348483204843304 -0.614340713838852 luteolin -0.202753944355477 -0.62987890024228 0.486593167915951 -0.539071346270609 -0.669717043237978 -0.120839361700406 0 -0.73322863145401 -0.609202060203903 -0.697825665825515 -0.462444031805015 -0.606027319683641 -0.685710854234437 -0.674399900435666 -0.718732004176904 -0.602296387263708 -0.238803885339454 -0.590554101819916 -0.750587517053 -0.264856387143813 -0.332612989267885 carbachol -0.262962034961016 -0.56339572563451 0.148803594971273 -0.537813907015193 -0.653510185721769 -0.353431449717274 -0.263062721713936 -0.659982312676811 -0.562457822253759 -0.614114805184884 -0.434645104955872 -0.557236021016117 -0.654360528108253 -0.662396628284296 -0.679837291073926 -0.630264008058959 -0.382661948142774 -0.647550435074885 -0.707250252248929 -0.311193337177735 -0.503584047422762 nicotinic acid -0.0966634010761753 -0.126843848844689 0.139952953492187 0.0805378023587738 -0.225790485098272 -0.0809444576821106 -0.061553782881222 -0.231087670117313 -0.31392279658271 -0.202479183351874 0.0347285787484692 -0.169923699346078 -0.201307992312069 -0.202142407164381 -0.13018127161333 -0.165191187484139 -0.0460816235190388 -0.227474034544178 -0.16352961056598 0.00700061047208737 -0.0397615300917673 3-acetylcoumarin 0.0782617206907015 -0.243058647227097 0.28602550483288 -0.111382349445591 -0.465139808633491 -0.0832101009469877 -0.368990332793808 -0.464924945314126 -0.433856201378631 -0.492939764095482 -0.313269197731121 -0.433458413088607 -0.437265039331936 -0.490029628265648 -0.46304678410213 -0.347275441497668 -0.291186043260695 -0.295219564053192 -0.463760153640031 -0.0936433496359814 -0.355345879816256 hymecromone -0.0328586198769532 0.036132474601366 -0.14300740569099 0.0112505288056956 -0.241807516435612 -0.205956456235006 0.173524227170741 0.110985274044383 0.0943096074648936 0.23462285280929 -0.0725963418532939 -0.0254858364489343 0.131079154836877 0.238359824217025 0.144541747832535 0.0407266424664548 0.0802514920346287 -0.224507821491333 -0.167779317818902 0.337433656565017 0.0664847354174982 (+)-isoprenaline -0.154957084151832 -0.0729888155641089 0.316177529215152 -0.0567437448979194 -0.102197343406746 0.069733357306442 -0.216200254239595 0.0847424723300077 -0.037988844713641 0.0339433205194243 -0.17905228241535 -0.173723969842727 -0.0817391681302411 0.0516310933657297 -0.0968336025355602 0.0403587945350952 0.0366992857961234 -0.058440508422927 -0.0881327520054557 0 -0.245758765181497 nizatidine 0.301418079722674 0.314443911555248 -0.028832637731883 0.0913059284435135 0.215011558168369 0.115781665269309 0.284529584889571 0.305878930036679 0.333164442640257 0.28161571130677 0.0206301338959076 0.266361244313268 0.143179055343078 0.28214470135611 0.282808984196213 0.277453961369626 0.141982838657896 0.271623099018544 0.171212589233616 0.23521652499245 0.0595048621990565 propofol -0.280189372588669 -0.383709415330369 0.35930679490438 -0.3768296178799 -0.302367371497863 -0.297265185187782 -0.131697620171026 -0.308353632916535 -0.496449441717259 -0.215449421574913 -0.33927022501767 -0.223631896850487 -0.451726885459244 -0.517494092696707 -0.545352827549173 -0.237752702507275 -0.129457739299813 -0.301287787577639 -0.427978808935306 -0.235078256910169 -0.332497803410885 pentetic acid -0.219200581487158 -0.0692645648707223 0.239133597225598 -0.0107401802212547 -0.0603964639300415 0.0835987137126487 0.111637385501194 -0.060943460703637 0.0165898506867612 -0.131266049005655 0.119970564325229 0.0560444346125485 -0.0976634057695213 -0.0803145826073459 -0.13082939627188 -0.0777532528046008 0.0633723256236923 -0.0846769426512824 0.0283589349748144 -0.10423552516613 -0.0778100859983249 crotamiton -0.107289889755281 -0.350464141367546 0 -0.262526258375481 -0.270101470151042 0 0.117562086649249 -0.334139960426964 -0.245149552488178 -0.289932801225115 -0.109484442378658 -0.282988844706842 -0.352146620000355 -0.3469228276946 -0.362502036981975 -0.337974994100035 -0.336609442657281 -0.314677928682698 -0.309747870042127 -0.253057581748879 -0.42146160412991 bemegride 0.0310530805363938 -0.0156522292615351 0.152378504946201 0.0974560072557357 0.0633542116019958 0.148212563170185 0 0.0677090948964351 0.0100443345417443 0.206854224716691 -0.0239698993737933 0.0374239997170702 0.0466019300777873 0.0126399454190538 0.015616692537265 -0.0157131873641786 0.126060468440062 0.0133983710864757 -0.00869686855961016 0.077258427935997 -0.031258246589242 esculin -0.101350787622367 -0.0846303284064662 0.301249748650542 -0.0462435502306508 -0.277596620438539 -0.07516635876675 0.023021206349932 -0.181137181383083 -0.166126505972384 -0.189889118814531 -0.238023471215419 -0.0903659411105254 -0.0838923948423544 -0.173532162550911 -0.181511238406245 -0.236694386665736 -0.117902294821382 -0.158300379287298 -0.352026284090758 -0.00422507507046591 -0.216825112733743 caffeic acid -0.105478931612537 -0.55133212098413 -0.109228689171218 -0.512767044042669 -0.530059578780532 0.165697838727556 -0.161158413404456 -0.543405637394831 -0.405011778022116 -0.373641783461499 -0.280840387181408 -0.469444442472213 -0.392669081974228 -0.296669803116001 -0.54098406308318 -0.449115042455676 -0.353552898238493 -0.25143497116682 -0.616679481570459 0 -0.409435221362437 monobenzone -0.418456120075225 -0.529227363436195 0.321410900492738 -0.339304881730058 -0.44182601343971 0.302923337905078 -0.231635472024163 -0.425362637326957 -0.386925502081446 -0.286547908894813 -0.435132175503091 -0.341101330664054 -0.474343245379027 -0.504509080163103 -0.626002348776113 -0.57020783221053 -0.354664599973225 -0.567730521918682 -0.464172038159052 -0.433819590955622 -0.234869725352647 thioperamide 0.177337359016001 0.580176136114554 -0.134822026160867 0.448188314441627 0.556638547435517 0.2729703081496 0.162204330094645 0.590815058626358 0.397197421410719 0.331596873522794 0.290976361166776 0.439900382440667 0.601254117139767 0.585918037613915 0.593452961598204 0.560995214683715 0.420488996327393 0.572651476207225 0.529869992943201 0.129675844083829 0.032033864168198 eticlopride -0.0955802426831632 0.321749963541268 0.125884210632851 0.282642680022785 0.528491708979822 0.400386572079663 0.119871198054096 0.326363949521461 0.330865325590275 0.452402516697329 -0.0337897548783707 0.27041821342273 0.413507747022072 0.442500529766299 0.303781613610011 0.446654407938295 0.160527163528867 0.410726043128044 0.467277346581832 0.0853993415343381 0.102412632080603 bretylium tosilate -0.236246342057867 0.216484820187799 0.084740491312316 0.160402126563301 0.2573359107585 -0.0795038318538921 0.0326761125295922 0.257749249903626 0.256478480412726 0.328908485701568 0.0362944201489546 0.133612700465057 0.178090353677631 0.150242758617725 -0.0912800759671075 0.240606892683032 0.159584845139504 0.255614511662429 0.164022811098826 0.227210320146116 0.0608258971791768 propranolol -0.319654142090549 0.0862684276929215 0.217255777600271 -0.148372279463849 -0.0585284141968656 0 -0.179819766181917 -0.0641062121774703 0.171233076996897 0.0704025742988436 -0.124780428211185 -0.0473126220484562 -0.060849836170221 0.0864919698302225 0.0499029361544137 -0.0522088743600422 0.0809848897047116 0.201455805735813 -0.00438337731019642 -0.166725072977202 -0.0936767971516966 digoxigenin -0.178457335253758 -0.0557050962672756 -0.0185717328533692 0.158072470714039 0.126755803622795 -0.207241278037894 -0.0731562377008059 0.149913364213136 0.0357337928522856 0.207812566516258 -0.0725673325964598 0.00495582413422251 0.0510689227055076 0.0473899186435561 0.164401896136243 0.106789230689552 -0.0879836350280596 0.130936738539206 0.182908017518826 0.0947834269589516 0.420041065537082 felbinac 0.146788460449813 0.650718874151704 0.266433910226089 0.593345485030422 0.66331518744641 0.203693952981331 0.151657220495583 0.537089402128602 0.568825047960931 0.613018332034755 0.464120831359373 0.487849230669136 0.634181910421182 0.661209831804314 0.651843572215329 0.616665989870724 0.388501508756522 0.656119100619996 0.691198318836941 0.214491163308068 0.444996464229877 diloxanide -0.131573683730408 0.38818831910433 0.130572629920219 0.324087707579127 0.3871225750631 0.242809451451212 0.221169102702788 0.484757919059562 0.504344978005488 0.428277533546399 0.326233708116754 0.462927586588724 0.406468533762403 0.50765947825146 0.508095053504589 0.358381982160525 0.303781071069528 0.497203063272625 0.516479578734957 0.406478393357294 0.148464176892579 2-aminobenzenesulfonamide -0.0839918521743262 0.498300082361637 -0.124545001364633 0.429453541684413 0.608467646164648 0.367777419077331 0.139012499974394 0.507338535331818 0.475092810765101 0.585648298895456 0.192586317488566 0.453358553725852 0.406894072144974 0.524149911556828 0.555721459195393 0.382750280316296 0.448241795623577 0.489755709726851 0.376552887780736 0.103871846008732 0.319645415477739 xamoterol -0.103694785359043 0.411191630397497 0.121193155640597 0.544637815956556 0.397671179670546 0.22042355996961 0.207371968430418 0.442179892430461 0.416963276438051 0.385040173885688 0.283589188815846 0.36711946733858 0.4065606723649 0.385695068570419 0.327017516392767 0.414557042175943 0.469953693234355 0.545604902498516 0.397662978311508 0.453249465525575 0.440825600192249 primidone 0.159423793682925 -0.0468777004213249 -0.0306641553053897 -0.326658055797398 0.0684111944315397 0.282864469887281 0.240381831415693 0.0525504113501053 0.015151332004502 0.0570591596350427 0.0468213646514398 0.0711087552633922 0.0676822968137003 -0.0410962741047602 -0.0627426491562464 -0.0774077236021321 -0.180380489150193 -0.0714561040523682 -0.30296787531627 -0.136071296370576 0.0107823323271087 pralidoxime 0.226342500623531 0.00721493518715435 -0.535270099545707 -0.0361584710753452 0.0833119940059887 0.0526053996033276 -0.047104662710101 0.0176086508081854 0.0651654433286048 -0.134325770037925 -0.0681738626890982 0.0316142406164639 0.0376876105799571 0.0455157124142751 -0.0194461384567558 -0.00298648265562702 0.163307877887601 -0.118969226528641 -0.0276533483359185 0.0093023527250556 0.0123188135920631 (-)-atenolol -0.236332452568811 -0.376030798846735 0.106927704141111 -0.128070850363287 -0.371792773982473 -0.108184271254594 -0.208350151068582 -0.390953797787035 -0.301763202981158 -0.192492945190594 -0.178140635967284 -0.331634587269046 -0.31630353755809 -0.260601721257492 -0.432116440538328 -0.390062282683821 -0.134356011163362 -0.412101082858873 -0.337211800072872 0.0445077578223282 -0.0365986288794186 meglumine 0.31964542007743 -0.103859238130826 0.072322317368625 0.0970164521465978 -0.121048760041103 -0.118988380085109 -0.100708872624296 -0.0866382818197027 -0.0709718351313853 -0.105223861995413 -0.116356277546311 -0.237238886518404 -0.0847300298253484 -0.0156848947467579 -0.0279880957558074 0.0145279695213021 -0.150737699306593 -0.182952175294097 0.0234165770335929 -0.137175545865826 0.00779462440073175 butyl hydroxybenzoate 0.0857060874165984 -0.143024561737896 -0.119203484162901 -0.26996765875088 -0.125587771757716 0 0.10982495082129 -0.291673060825961 -0.103824821142989 -0.147808293561945 -0.23806680063978 0.0269311873709087 -0.166181362117408 -0.0974693999053904 -0.0916422699715927 -0.0617594977923593 0.218351644683421 -0.154302410363294 -0.208891950424138 -0.0226542368285177 -0.25066454940769 metyrapone 0 -0.628520637083611 -0.359324124532298 -0.539500587644547 -0.568282044723631 -0.156778975928545 -0.147658811763125 -0.619032590469219 -0.609125376717163 -0.621454784143095 -0.456440255719873 -0.533663879831016 -0.631152776069716 -0.674517195507519 -0.678161821907388 -0.645209821857411 -0.533093714400327 -0.594334607227465 -0.730285954702155 -0.400847635525249 -0.485567894536414 estrone 0.253128586470309 -0.0218455453569921 -0.163853567277592 -0.114814157698807 -0.0545269412778658 0.195472112866271 0.293762146055538 -0.0949882886024962 -0.119665908001421 -0.182460534459209 -0.0112089686708279 0.0787386552272677 -0.0302593947580923 -0.0315425144297156 -0.0972456539146269 -0.0658467385826468 -0.128206408286063 -0.179806280634919 -0.243656415663249 -0.0682194154210061 0.00869892012139459 rolipram -0.467803609458116 -0.414611839108042 0.089356952130269 -0.340738675320799 -0.316501005829931 -0.112888423890598 -0.377042737587634 -0.340069311037467 -0.354610016039899 -0.29191136522516 -0.136436395055065 -0.25325614629167 -0.484513729923227 -0.415602836990848 -0.438713856043717 -0.415315996910088 -0.150813390591198 -0.211491264938499 -0.342895165133967 -0.136225494761372 -0.0386756317325755 flucytosine -0.0915109803991 -0.337535731576703 0.0942653081606414 -0.26737728095546 -0.441805106173005 -0.316528018295052 -0.141962755767094 -0.44226100071479 -0.164464192350225 -0.398721388189154 -0.0377367591635175 -0.37012093924528 -0.430481896931264 -0.239624748744088 -0.434182437753116 -0.323887142464684 -0.0761728907469225 -0.336116398989629 -0.304980173246347 -0.248970274521608 -0.206178783185363 tyloxapol 0 -0.672413205482368 0.23621144137003 -0.585818522987063 -0.586109488974586 -0.0909003962404333 0 -0.685107774822647 -0.627845629736099 -0.689691518584094 -0.489340469727228 -0.599651852788259 -0.67699341720182 -0.711853215684963 -0.72530596600765 -0.666689422908117 -0.450874247326069 -0.653289230545072 -0.770889618995833 -0.546577870754109 -0.41950761194134 cantharidin 0 -0.743212520789033 0 -0.566552396112159 -0.500515906438912 0 -0.40603688088186 -0.504008747647488 -0.720892002713753 -0.747836296708276 -0.642351681482985 -0.641109658234812 -0.755377648504069 -0.772271185092173 -0.670235061632419 -0.727237896379411 -0.591688088843826 -0.6592326693711 -0.831020033865737 -0.481145882749359 -0.793234981867439 aminohippuric acid -0.0542633149609785 -0.58554218184223 0.100057516776204 -0.483815324424163 -0.52922274548901 -0.226128567547974 -0.130809181950301 -0.604451214453974 -0.372307261059767 -0.464934601751077 -0.36176792984545 -0.538476464801308 -0.617779186853174 -0.507448917215193 -0.548627148486199 -0.569540757302417 -0.46757264460253 -0.53096022349101 -0.650096628210665 -0.232313824658264 -0.598973413851484 urapidil -0.0562505390334768 -0.48404744129631 0.0339286951548605 -0.18638537146058 -0.327227684047673 0.0604012437393133 -0.202188458092941 -0.376386754935097 -0.410485529035081 -0.548306536792721 -0.259852402674449 -0.296308761156373 -0.33784390340882 -0.368197599491332 -0.222200821856495 -0.463114491399582 -0.256728683468166 -0.417481435844027 -0.376682604174874 -0.226452388500565 -0.152185023421582 lorglumide -0.126974334660034 -0.599576419977261 -0.315787867849682 -0.451046686283302 -0.585596774598181 -0.231566011526326 -0.221215406193062 -0.595449285755151 -0.391340541175212 -0.508720945306561 -0.374234829189567 -0.512675577024325 -0.608444510051161 -0.625779599851874 -0.558269527662521 -0.579618864887646 -0.315349943251939 -0.561329429922713 -0.616392173991025 -0.158839608703754 -0.407585341018727 tonzonium bromide -0.520951769234108 -0.547029353296649 0.0458641733041229 -0.475530019278176 -0.420519499992063 0 -0.289256540484639 -0.506664827509321 -0.32920574658552 -0.560664851089651 -0.388554155739793 -0.484609466883404 -0.566360508486488 -0.506717156097231 -0.546426903933081 -0.550579354232634 -0.519291111514373 -0.559535732732149 -0.491453280741711 -0.499943076732716 -0.210930063768526 (-)-MK-801 -0.0928722816100925 -0.597940014024243 0.123321448697117 -0.505416550021923 -0.270478359997698 -0.204035872334078 -0.196300779463842 -0.493910111083418 -0.486642126348766 -0.549136433142365 -0.322184829117212 -0.503105134268968 -0.611384101839893 -0.634583305941276 -0.628345813688467 -0.603199013002307 -0.493694521818132 -0.641254114654036 -0.633173829201075 -0.358873323577527 -0.585958976994216 terguride 0.225651444698269 -0.234711288909474 0.0749931716759082 -0.165662585862738 -0.221510123621329 0.0658484069161999 -0.0588839902617675 -0.0903886590553172 -0.305185429531491 -0.340604405373 0.00226544869608105 -0.186989421535633 -0.16882985442007 -0.206808681668594 -0.314479462487634 -0.104371890740518 -0.246908684419056 -0.218265453448762 -0.283456900239885 -0.176960095351396 -0.109971875466091 florfenicol -0.238741801779575 -0.31640471400426 0.212471210581101 -0.376769072927465 -0.204771160404234 -0.292908696201724 0.0149290864663732 -0.162279639777468 0.00265358412330181 -0.351915173303743 -0.163575375215603 -0.344899578967026 -0.386465544463938 -0.384487327671082 -0.370109806132229 -0.373258259901037 -0.370344641684005 -0.567101117217829 -0.0976716597007368 -0.280232460786167 -0.247322952878369 clioquinol -0.290627179847994 -0.54216237612131 0.34177625630331 -0.401982931034837 -0.555088958886233 -0.220806600910988 -0.258169241211201 -0.579313944152306 -0.510725926907336 -0.584187828694313 -0.557924826606468 -0.583168562030799 -0.489954712465105 -0.59195008375891 -0.616041212288155 -0.528590116951294 -0.370092847414284 -0.553929396390781 -0.440950587486221 -0.432420253359421 -0.412502307779789 N-acetyl-L-leucine -0.120797736305877 -0.604110091436538 0.109058691745407 -0.416549072201358 -0.602103537446256 -0.113427372136587 -0.241273006316616 -0.638156998708177 -0.564681470964606 -0.623241915272439 -0.429328912605085 -0.566605137227774 -0.637303380640382 -0.674664167366138 -0.672757577939339 -0.633584656617015 -0.515710942712931 -0.512627093600221 -0.708944410146692 -0.237965558416422 -0.543615867111522 fluspirilene -0.421206402089972 -0.566200988588796 -0.114971347128451 -0.471655463698673 -0.524965928193508 -0.0930300682610401 -0.587151430832591 -0.595448588284511 -0.434056840654975 -0.590501762749081 -0.585118605848268 -0.571180827574271 -0.649644777252194 -0.668732262545691 -0.701055838172177 -0.563610310291654 -0.48813087643957 -0.59802807627206 -0.66088647423484 -0.547476217621469 -0.566030736191857 idazoxan 0.10349814175003 -0.388552825737841 -0.151079338842212 -0.386977994714306 -0.307005009745911 0 0.00588539061113735 -0.353451656387164 -0.290790429912465 -0.291843577511911 -0.297247625013852 -0.253115641713744 -0.309938966276284 -0.404520554915702 -0.517416756390531 -0.47627323151135 -0.392239531061942 -0.430050870736119 -0.383796696962923 -0.343780438980226 -0.294078457487127 bephenium hydroxynaphthoate -0.330127671530427 -0.32066171225568 0.211160595137903 -0.425342749174754 -0.461345298716663 -0.153644775972495 -0.182109465767179 -0.485819152496063 -0.274971919527355 -0.316341102021967 -0.278061448542642 -0.371032422969143 -0.391663582448695 -0.424227399910565 -0.499953780700823 -0.401184192523604 -0.300758221520418 -0.21581446859121 -0.417539521167983 -0.266519095395176 -0.248298695766609 altretamine 0.112686188643037 -0.0824528020982175 0.120078300726808 -0.291343798896958 0.052628798027046 0.00365989568444672 0.190806236053959 0.0983104221054289 -0.0308426531783138 -0.0554912998678044 0.117587592022153 -0.0308325803817701 0.0599515452973167 0.0363842998198192 -0.192854214925597 0.0637552379541234 -0.0199204741438337 0.0505196738593166 -0.0436215685514776 -0.14951932273497 -0.0514654832575628 megestrol 0 -0.0713485093593504 -0.478711407921375 0.108135580272868 0.0726797608935766 0 0.0715407180174143 0.0991021624631612 -0.136180477426347 -0.143765485013802 0.0230983742114921 0.249284262909855 -0.176161823927177 -0.197266573016111 0.0395302017974083 -0.042776231907932 0.0460236483441292 -0.12162952978955 0.166030211753427 0.0249224844497054 0.132747735086674 oxybenzone 0.412446178092268 0.544190806280575 -0.269528851914799 0.414218935007221 0.482641404007465 0.0889623346581714 0.434206190688775 0.50179222156147 0.258482199038359 0.351240172221543 -0.000717029460458513 0.237793318290949 0.401118535956316 0.421832920698055 0.37360919694028 0.545243705342661 0.377320451100403 0.51730087512867 0.165988632188524 0.331075683765853 0.254122310047108 pipemidic acid 0.237478556025493 -0.185207603978958 -0.20633093339217 -0.281954733904398 -0.153690910911393 0.273950140477705 -0.275546037911964 -0.0920124548540661 -0.0785445798985676 -0.0130456455867314 -0.148097972961373 -0.0767035587482549 -0.133952077185283 -0.162668131708982 -0.188430248853592 -0.185051024093797 -0.197245155330058 -0.133191582195594 -0.231339639201649 0.150206536289372 -0.163998972627325 dexibuprofen 0 -0.206204105901693 0.0922379448700751 -0.231525963719617 -0.164395708920855 -0.0991725728552949 0.0364942245658128 -0.19609761004952 -0.10299856108959 -0.179106146794203 -0.146498024948369 -0.0565502586840261 -0.190059179257156 -0.209433079763058 -0.200707013061151 -0.191971364945995 -0.132016540909544 -0.192207385563381 -0.198522100322044 0.121609793958996 -0.17731604539906 flurbiprofen -0.253651553050956 -0.307075417402764 -0.00396314299641032 -0.182847823764251 -0.22082607479817 0.0426669425740367 -0.0677991982548651 -0.391793882882407 -0.146222068653198 -0.106288121242841 0.072744910161621 -0.19327666804026 -0.390177200900361 -0.316807242889729 -0.42057810122351 -0.29907146041612 -0.191246115236824 -0.364748832199708 -0.234023101095501 -0.19173631205591 -0.00754978912909697 prasterone -0.0538335556885646 -0.249981335951705 0.132082874952762 -0.132050404533697 -0.199869690885806 0.0923344011320628 -0.207610265593797 -0.110811407437133 0.0313827346666063 -0.25948017735745 -0.115434230273653 -0.249509171823898 -0.240861141385862 -0.247527215505705 -0.296050609636012 -0.134743311084612 0.0130657946450393 -0.133480384310433 -0.148952144160224 -0.121026460066216 -0.208963240674352 desoxycortone 0.17463122850167 -0.285813724392005 0.0699147731992447 -0.434193230726048 -0.179278645411491 0.0371681144187054 -0.163810840516658 -0.334676059993886 -0.281293955893366 -0.48259202230044 -0.367343446149448 -0.344757110674723 -0.402998600616326 -0.389023685047775 -0.412503774684601 -0.347362140313422 -0.325227207283734 -0.227482936643185 -0.439235980739011 -0.17257926520416 -0.35362475448279 promethazine -0.498531163481579 -0.626393346612327 0.167770058164126 -0.438737230439054 -0.618315584921008 -0.419006059001832 -0.479822513265478 -0.64430701813662 -0.479587888167703 -0.475479466810616 -0.451236517380763 -0.600316426608454 -0.670429322514873 -0.669506483212188 -0.684364114224034 -0.64401191885606 -0.51105339607412 -0.647049783393805 -0.54059006068611 -0.520145787249077 -0.636918286205129 dioxybenzone -0.2479364404157 -0.389462507271986 0.19282885913794 -0.271391599980904 -0.529333404532628 -0.253501689623572 -0.339072009299053 -0.475757270353074 -0.374966430730069 -0.373705933773355 -0.267415871773172 -0.484401919982115 -0.405845450524606 -0.425251975380668 -0.518497929458279 -0.374787159368293 -0.332500242232929 -0.46822220649745 -0.25723112239336 -0.278577641483665 -0.332287664001795 etynodiol 0.181962938274523 0.339384096303107 0.109146389552418 0.349002606813673 0.246170308730455 0.287641457319312 -0.182613464266039 0.224532412350627 0.177051071797316 0.0739792654478809 0.199552841006929 0.0889003129891141 0.213560763901424 0.439299977584541 0.187383616801114 0.205013990916405 0.213431672513997 0.288612282931955 0.315370017385182 0 0.0410587241004571 nimodipine -0.0641480904976867 0.331383062642295 -0.238657157357005 0.325908197014086 0.292345695932469 0.17627751608733 -0.20720329714928 0.247443969069661 0.346347196336032 0.344393645168556 0.196099614973335 0.259878859864993 0.232272458689095 0.338660981759879 0.320182770826509 0.295446214600382 0.314200515775633 0.339294981342839 0.350744183586653 0.120412848206128 0.0692260022873281 nilutamide -0.105507308350572 0.00286063267156615 -0.363403162881813 0.0721867943130051 -0.0434207435914589 -0.152648148894754 -0.0165031186470784 -0.00487991208809725 0.114692222337868 0.139557678756784 0.0582330800296564 -0.030787748446026 0.0776636515388248 0.0144571123594303 0.123779905554264 0.00821771171538649 0.128611738339577 0.0843848738614578 0.178162593770524 -0.232049266346965 -0.148124733527343 ursodeoxycholic acid -0.161555975603959 -0.651888508575659 0 -0.506398636824751 -0.584754369949785 0 -0.320039819850607 -0.641360072592696 -0.581440206924557 -0.649368230470852 -0.477558198954378 -0.553629352205735 -0.645116676427134 -0.705994777454406 -0.700614057812424 -0.681761820442553 -0.577219017020281 -0.622644876949376 -0.696908701106005 -0.334919180257113 -0.549919939753866 chrysin 0 -0.623060520741314 0.364790477829084 -0.543952132664217 -0.663918745528476 0.00285537265838927 0 -0.718438836812383 -0.59718196109876 -0.707714208665569 -0.481809602057069 -0.576264026035227 -0.715572425414604 -0.701261094321777 -0.749613597978051 -0.619844506823034 -0.205815721213459 -0.617605517769904 -0.7679176931658 -0.224668124247669 -0.603163225098784 adrenosterone -0.033789309727839 -0.5335896540014 -0.0375648652712355 -0.515444807194006 -0.371280742648399 -0.129151758294385 -0.186339626650588 -0.41791678222804 -0.463369435209768 -0.535623922153266 -0.388766475432811 -0.421237657990055 -0.571082610522436 -0.585916850492022 -0.567972803439065 -0.581982868446683 -0.534055313593053 -0.521926545893962 -0.604050151398362 -0.367772224686599 -0.472643340928574 nabumetone -0.19856452432267 -0.417692414013269 0.0345239285801049 -0.352417543866527 -0.271038038064641 -0.189427732277504 -0.0263804573246724 -0.282078073149097 -0.252635406543324 -0.164214110696591 -0.190932794987702 -0.228974647719937 -0.526789579994856 -0.340058813414597 -0.32194938006161 -0.332990754704811 -0.215901884049876 -0.181101476424181 -0.41235187652208 0.0434812858109649 -0.0495805911537563 bacitracin 0.16098041159459 0.00410365769223383 0 0.107998109689363 0.0973755531630573 -0.0316019289957664 0.230028815408376 0.284541803071812 0.342690080164772 0.27916942700904 0.242048198159484 0.184460639794541 0.137743355704701 0.109022770941402 0.334907264511614 -0.0124672126702614 0.199326784934557 0.153570537386504 0.164354145904075 0 -0.00147699943526432 ketorolac 0.246175923586634 -0.35643616216192 0.0772395778383678 -0.423431732285806 -0.132637023297968 0.146057013453794 0.181343893342895 -0.156253485709776 -0.398513443746827 -0.275895987831225 -0.173702240828186 -0.0386966087611491 -0.288881568298344 -0.30869770119261 -0.201448793428507 -0.409713629491897 -0.338408697959177 -0.369766312478653 -0.330706416931716 -0.184299532997068 -0.0199988320359729 adipiodone -0.414860086074351 -0.320552809248478 0.281599663377911 -0.306259492106901 -0.34229519061471 -0.134146869956566 -0.40382539687902 -0.351949466784222 -0.0973783650414027 -0.209456155697435 -0.12486919966801 -0.201153231466832 -0.324710131903177 -0.228329485464999 -0.210376172092948 -0.208688348635046 -0.094667039537242 -0.213779916058138 -0.171271921402141 -0.266342857266264 -0.279340969181091 octopamine -0.109603899824551 -0.081737417726816 0.314462805340658 -0.304395076622262 -0.219582796950352 0.085625919677171 -0.0846656271633515 -0.110191692942258 0.106192678743122 -0.0614858639450072 -0.0958970325749359 0.00564676824471574 -0.278846984869313 -0.0674689553467214 -0.212941749988492 -0.256016282081289 -0.0478559878566007 -0.293721997545308 -0.0262718816800717 -0.11142796769383 -0.151116008066382 proxymetacaine 0.000951708032814677 -0.351293909088131 -0.312748679632319 -0.354478255877769 -0.338486477209808 -0.00016010426775806 -0.110481443151985 -0.364551200448209 -0.310053278545277 -0.411080836569903 -0.262844689868759 -0.339279131234671 -0.41930071361498 -0.366640835367535 -0.395338711804608 -0.382082389788398 -0.167498325932262 -0.186250468992619 -0.379303345535269 -0.150548477479041 -0.16345932274175 proxyphylline 0.0578537054905248 -0.488677697631158 0.119603434049435 -0.467894608482061 -0.539433342423228 -0.173996679006116 -0.210443511681202 -0.491579496942328 -0.552006434558496 -0.564105308690596 -0.221998826586755 -0.407206926944728 -0.497594017413014 -0.482508453858654 -0.644649960734388 -0.517434043247441 -0.265625037082993 -0.373677073833205 -0.389466237384052 -0.334811550605102 -0.491309209024813 atropine methonitrate 0 -0.276896731835597 -0.183071444639029 -0.415212748925796 -0.225712669700201 0 0 -0.367002236878151 -0.118762176986193 -0.194755232453621 -0.0917957809096284 0.00716764256630494 -0.26082049220018 -0.304176036800339 -0.308004591113582 -0.265614013845265 -0.19132780799039 -0.246366394589875 -0.214460831037233 -0.319285487798467 0.161136988079519 nisoxetine -0.34997514118611 -0.453124975392376 -0.00360547173995254 -0.311861055596533 -0.452564460329726 -0.136902856810786 -0.406090795513702 -0.587980990671914 -0.398109431797201 -0.457054359243686 -0.317990080893141 -0.290244614612925 -0.438401274144084 -0.603785201138296 -0.600214610298179 -0.472118317181256 -0.396388994026041 -0.534366123205058 -0.324498938321462 -0.446016533129599 -0.368302685874422 Prestwick-920 -0.189842699305556 -0.487268223513118 -0.000472579071601947 -0.397735752631316 -0.399130586946383 -0.244955871862867 -0.0638990091339846 -0.379622167778143 -0.300932912763574 -0.343338813005801 0.00937739591971776 -0.0213759659908441 -0.406315004466493 -0.517449567698083 -0.511555131831284 -0.523627147486647 -0.409378469923834 -0.491775435663548 -0.405369103753111 -0.279080436714332 -0.243212598443527 protriptyline -0.40734621666257 -0.560616051695975 0.351824840029079 -0.440089556769102 -0.430279408268402 -0.348501303025128 -0.549469755989296 -0.633625918922991 -0.545048372035385 -0.685802120384162 -0.599963470274238 -0.616148316099988 -0.686445829588079 -0.620101920339814 -0.700564446861931 -0.553044879956392 -0.418602983942263 -0.558822983866283 -0.548822317365022 -0.530307085074192 -0.433884858001669 esculetin -0.0737056145174287 -0.223243903693643 0.00666759651268748 -0.139383508879675 -0.320776497357265 0.00812513875975492 -0.258986121406079 -0.328955678179449 0 -0.0405895560152578 -0.352212236560467 -0.0398500048149041 -0.243324243041967 -0.402949729076322 -0.426671477961189 -0.355094154396002 -0.318553651094287 -0.368919306196251 -0.216555055467221 -0.414772844156812 -0.00469382911351661 nipecotic acid -0.271038749067555 -0.566283334658899 0.272330286841051 -0.467210232356329 -0.542058463312904 -0.0548383841927794 -0.251774379373776 -0.611651105307348 -0.559367135018629 -0.568954083236777 -0.396974853853964 -0.449632268230416 -0.558329992747822 -0.590189679403979 -0.645730293849524 -0.555446445741615 -0.457497816600271 -0.55979908376191 -0.574120116756734 -0.444339891366488 -0.385711467363783 aminocaproic acid -0.0661911533017594 -0.344778121478221 0.383496988166732 -0.249338886349315 -0.264845385291421 0.218748235649243 0.0536524115129402 -0.430311066313334 -0.351955052756337 -0.413876023693623 -0.180853143404476 -0.285490900358051 -0.457934781904466 -0.361567453317053 -0.608856502659179 -0.329127836440102 0.158124774491896 -0.27845134724011 -0.350853985669594 -0.0533666653119744 -0.229051074790133 denatonium benzoate -0.138994706690955 -0.526147447618037 0.145562276737948 -0.444704702434428 -0.549501055933285 -0.273402178583536 -0.337230956069769 -0.532419922818494 -0.476267051209084 -0.504426969648785 -0.283025294614413 -0.469619782182137 -0.581232016562147 -0.582227926284075 -0.611422249891764 -0.544171223842867 -0.363143314693404 -0.51100542383596 -0.601036033617321 -0.335385354674141 -0.422530428699458 remoxipride -0.419868187064222 -0.548076313724586 0.0632620629382713 -0.35602048498599 -0.574166968739133 -0.367422830686472 -0.258566506605561 -0.554519612501914 -0.421610005277671 -0.360754808856678 -0.315877260747594 -0.43047528761568 -0.610963032984605 -0.572796086831465 -0.487218075903151 -0.584174604259039 -0.23597003776873 -0.265322433855287 -0.356623085454427 -0.30035709166167 -0.416707947187258 Prestwick-981 -0.301864591528946 -0.0755301422056645 -0.151648032426747 -0.300448866484742 0.0111031790938615 -0.254050580611143 -0.213202927171142 -0.198214637449412 -0.0584232163445155 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0.483436105457966 0.441874072760795 0.286637760814224 0.428958999635695 0.411834774311494 0.0184164115040662 0.353428847243713 clofilium tosylate -0.144601478935549 -0.230172242170999 0.3693097713148 -0.187705542129601 -0.195103908861061 0.135413184718328 -0.338928072564521 -0.294980579387214 -0.166843481092618 -0.241531661968273 -0.296405603555538 -0.184670777409682 -0.214360079335764 -0.228092761048127 -0.287478961612772 -0.243570231047449 -0.388375727662091 -0.238983103630473 -0.234848539137299 -0.35856759454307 -0.397900646745654 quinidine -0.175614059687229 -0.387297290624145 -0.25312600427404 -0.159758068653257 -0.184867999790664 -0.141955385905689 -0.177081394288621 -0.240852247807083 -0.0419349656882702 -0.186525556019709 -0.236981257474555 -0.328793503422616 -0.234236474425779 -0.441238628675243 -0.297225814523886 -0.246067267344317 -0.14332188557053 -0.230764822485299 -0.474252046000611 0.155520555491706 -0.184472385283064 lidoflazine 0 -0.0540233740977691 -0.0854935559798314 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-0.665459715299896 -0.474847411327443 -0.562170993676878 -0.645681855569462 -0.500241460511661 -0.626886425411419 -0.502136510267175 -0.612583093337194 -0.613116859029562 -0.579299776192446 -0.685090803708463 -0.339555103179579 -0.137225388219436 -0.369915021686864 -0.210928181457473 -0.46078240384807 -0.349756459763253 fluocinonide -0.360571300832659 -0.60451569481973 0.285808804840728 -0.479681549482622 -0.64096251502369 -0.367238053994755 -0.348980368080356 -0.540222070163621 -0.201965887424752 -0.591466490730122 -0.325716896324658 -0.444398927901467 -0.523767998850039 -0.651041807491119 -0.620935238587846 -0.462444076818816 -0.433318642955466 -0.4735724538705 -0.536134459331408 -0.435785482804851 -0.25651421849069 piperacillin 0.0385703492241116 0.110492556904007 -0.00888356691075938 0.23658720354372 0.123763903366256 0.266349399251712 0.121667842006515 0.133662273946309 0.160272482256888 0.0944438255152326 0.053791569017842 0.130622046227864 0.10157753216471 0.0959718327985801 0.0781223428284889 0.100890522877904 0 0.21316799088454 0.082957390369801 0 0.118169749110858 cefamandole 0 0.600767726952303 -0.0286672351091385 0.453228232991303 0.361596870001595 -0.249002752113832 -0.0954999592990395 0.614184980917002 0.402469819338337 0.603908894261657 0.180432320979216 0.531666026215789 0.592442117935686 0.596933324260082 0.321715720226289 0.631092177574806 0.431906346069572 0.561071053392107 0.608732230550278 0.150702650151402 -0.100564657489892 levomepromazine -0.170969576404381 0.393549265516736 0.11115050165819 0.431848795806389 0.468723460710995 0.02325390685828 -0.201871802290434 0.463469863782611 0.364251335438952 0.457218166964256 -0.224588789861081 0.364267157632087 0.518565564592361 0.480786815857702 0.49169595064582 0.496510904058694 0.166920085520785 0.322729510311283 0.49767840511041 0.148581013142559 0.0544760470809364 dienestrol -0.0455739356930042 0.022295947853298 0.143967113338284 -0.055202929605997 -0.0663389089778562 -0.382400831303289 -0.155142108696852 -0.0119529309941264 0.175888881319977 -0.0582733408706109 -0.0157667841537012 0.0915305281303008 -0.00529965641325318 0.0169583954703156 -0.139106963670622 0.0499132167513161 0.216487227704763 -0.203701033354153 0.0269089543895396 0 0.0250112256194164 methacholine chloride 0 -0.695836511234724 -0.132337280738656 -0.48525608328125 -0.664048634330696 0 -0.465668309534068 -0.696376702411465 -0.365663769816214 -0.507496083790389 -0.277387511804883 -0.475334954732974 -0.689301751470104 -0.700117812059187 -0.721136343568453 -0.493697935498438 -0.35426078983808 -0.491138108981027 -0.690092556231791 -0.257553345399657 -0.421465997699386 cromoglicic acid 0.220464900226608 0.0435353020318116 -0.324642316757153 0.317041470888138 0.0252660838725939 0.113167039029807 -0.0312754278612879 -0.217890661011951 0.219606613761743 0.236422683822576 0.184916258148858 0 -0.233392003776712 -0.249251226142753 -0.289079313068641 -0.215040694342648 0.0363674173367043 0.0048862760669309 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-0.0239785905823546 0.0785699822908992 -0.033018365781092 -0.156355558003975 meprylcaine 0.0175470450486948 0.063392808585365 0.228200960407949 -0.0962061593792456 -0.153555789143006 0.0642003739362129 0.192784404549223 -0.194979340601771 0.122073482688939 -0.0868716055165356 0.0227754986767975 0.154505856272643 -0.121477162509278 0.0679555327276201 0.215280114724575 0.102893988042993 0.208846125231103 -0.0546861809292074 0.11629500581131 -0.131246576934597 -0.189206121385183 cyproterone -0.0122623894566532 -0.585844013264014 0.105991846443193 -0.356358391329091 -0.536831021530222 0 -0.340462062103388 -0.62426997951325 -0.559439466594723 -0.667995952304955 -0.398801918466065 -0.453658772324781 -0.52458317646273 -0.645220723797192 -0.515878914482794 -0.529524412936254 -0.139534429758467 -0.620575575136665 -0.535719283551291 -0.0726086843494077 -0.554217220754933 Prestwick-1084 0.0776135260360033 -0.693056503103321 0.237578610557384 -0.611268094034447 -0.651286970176356 0 0 -0.696748541663807 -0.632022058596883 -0.756364381070174 -0.459632871968664 -0.613127902951704 -0.716447902318265 -0.794912036658001 -0.758007164819474 -0.70053451223829 -0.593156385041767 -0.696683481478089 -0.757920594106902 -0.325317583515909 -0.721882444630522 sulfadoxine 0.191720565109944 -0.556512663173168 0 -0.637740022724162 -0.207716584091582 0 0.148916654020457 -0.425028263258643 -0.329131780416973 -0.420675056981346 -0.251978504617603 -0.340705335655228 -0.566164035515363 -0.584434116178429 -0.416245995248516 -0.401593235715035 -0.374100097210295 -0.546876502727277 -0.596823156752478 -0.377100406462066 -0.208538651706868 natamycin -0.334677942439216 -0.653847283830963 0 -0.452712251240745 -0.626974252932204 -0.127912513030779 -0.464856067644699 -0.655868052416679 -0.593209023678887 -0.626633786708109 -0.23786368334236 -0.55577785669512 -0.642316850123064 -0.647459238788777 -0.678003706843384 -0.652684227027385 -0.45737442454015 -0.683503014705887 -0.672566423589357 -0.385735233131415 -0.438288305214741 saquinavir -0.376241729107098 -0.361722735618225 0.010002259335474 -0.314561956736045 -0.391627059255274 -0.203573938583229 -0.297289465399323 -0.412593665028836 -0.153915520884299 -0.401528415482529 -0.206028309255496 -0.375979508819154 -0.397547750853158 -0.411998816733985 -0.414262855365975 -0.37341830778872 -0.261272247505714 -0.359090350974456 -0.324011680597522 -0.409453858159047 -0.207072907346298 sertaconazole -0.338910947814775 -0.363079406676229 0.206233987027726 -0.35984895297564 -0.519234817242566 -0.164960857292179 -0.338016104184639 -0.485050455024361 -0.297277171132596 -0.400459290912447 -0.295022433656984 -0.383514033252716 -0.463339525744201 -0.40412461846992 -0.472392253623968 -0.374950028394507 -0.309914908920891 -0.401691309126806 -0.398961142516033 -0.189049537755885 -0.442713728222378 piperidolate 0 -0.687213490601727 -0.0774291190283141 -0.598124172081266 -0.739446721888532 -0.248402343307663 0 -0.705936646317568 -0.612538754904955 -0.72038706005737 -0.393982802102257 -0.632911434896677 -0.670621229560302 -0.741672044840444 -0.728423958201438 -0.676426220497085 -0.583072146448644 -0.689426788096971 -0.736724254060804 -0.434932350439517 -0.27718368578372 milrinone -0.228982768517375 -0.69760385012199 -0.192906772179146 -0.692129778420292 -0.712951263836147 -0.124356329425414 -0.116774502531556 -0.677483670321078 -0.576208440602968 -0.664036750284772 -0.322354408783525 -0.586630887219798 -0.657089652093758 -0.724893426792028 -0.680624426263109 -0.686012124094484 -0.583580827358453 -0.681842637581447 -0.735734050752664 -0.569094087133834 -0.551006082457501 dexpropranolol -0.14900339386905 -0.438446077703203 0.138774053721407 -0.364204151913807 -0.551360548382166 -0.164346538107633 -0.126588685205466 -0.587774236851208 -0.52473225126619 -0.634139702138841 -0.432381153824055 -0.515281979159538 -0.59205616542998 -0.623469132993305 -0.615661575828924 -0.604305960114947 -0.405152701455958 -0.579448418806755 -0.696641429196567 -0.444336657621359 -0.497536650447029 Prestwick-1085 -0.329632622531461 -0.343028971813735 0 -0.350201837929102 -0.369399376537119 -0.176460924128605 -0.0768164605510072 -0.382893959171919 -0.0443430716870101 -0.299899966546416 -0.178181138973509 -0.265469410441133 -0.347024575001338 -0.39118903834953 -0.384627597205239 -0.337250434662558 -0.226932502999019 -0.348341815113985 -0.369411308095539 -0.252092118291779 -0.203189061763032 cyclopentolate 0.172685689055254 -0.233431279316468 -0.136151896790768 -0.153450231729267 -0.24090195368424 0.202693166123277 -0.0546356999614764 -0.226750710074175 -0.250496888090625 -0.246241391776727 -0.114062957582097 -0.164786840936621 -0.228324511555228 -0.28075142577196 -0.237968901434684 -0.121325085229827 -0.19453810490031 -0.250754603242984 -0.297103355628793 -0.104077548265887 -0.136179069210588 verteporfin 0 -0.598837904835402 0.208713842517208 -0.497865040532629 -0.589441545030987 0.11834992768722 0 -0.673801183012818 -0.581876268719529 -0.671489997601062 -0.408833220467683 -0.514331611005635 -0.641720140132839 -0.667098290394887 -0.646758253279912 -0.572234847247391 -0.491522966659656 -0.629149563864785 -0.703705090264659 0.13592902624087 -0.435674726803852 ronidazole 0 -0.630086383841474 -0.00580544487296645 -0.53437744874706 -0.54185790401028 -0.0304460193156691 -0.327033592286534 -0.589952315735824 -0.597330243006581 -0.632485134203175 -0.276898188837935 -0.574695347465725 -0.663230019953413 -0.706924747696108 -0.655742831223759 -0.6320230843036 -0.363435440941961 -0.566524688881502 -0.665439222902453 -0.363362293224795 -0.605660987991262 repaglinide 0 -0.703291843773467 -0.109161761542658 -0.617236374945317 -0.662191863580212 -0.266409047951154 -0.277733824364632 -0.713956461509207 -0.664105085737864 -0.688710924528155 -0.438470371987449 -0.636738689195826 -0.691891074515024 -0.743620378970925 -0.771760859862224 -0.719336250792959 -0.622384471303253 -0.729593989901835 -0.764629003380052 -0.43455898190259 -0.610183617679216 trifluridine -0.261406300570588 -0.474582201228437 -0.132885336879547 -0.442072768799317 -0.542288733666518 0 -0.32018344192769 -0.572235722778705 -0.27730006836627 -0.554069876467948 -0.429529469275228 -0.30141810760219 -0.435961075039095 -0.500734072029924 -0.60529097756144 -0.347860704871714 -0.29899624116138 -0.591693032653273 -0.629671951470409 -0.548194295047194 -0.333345531739383 methanthelinium bromide -0.159494704843483 -0.0898594186721288 0.123464047145424 -0.149679567178885 -0.0938743789182058 -0.0901262701431075 0.012364405818206 -0.00338647698781983 0.0877650870864834 -0.193233656941448 -0.0149736806209424 -0.0756962952545625 -0.236731513107263 -0.266170949509216 -0.275557433094561 -0.229816695837349 -0.0104819959839135 -0.218977702250301 -0.155591626164143 0.0148943869844484 -0.0823812836645177 ciprofibrate 0.128291794390935 0.246942901789524 -0.191247965558275 0.0813710557503345 -0.0120021124833247 -0.161839450459952 -0.105499358589363 0.0728945650813595 0.15910427730926 0.0749474110000992 0.128279033126857 0.108997414359654 0.258859114060171 0.271422070211089 0.245753677639707 0.295414858628409 0.121298394671026 0.119034499682188 0.212941562552884 0.130354404317732 0.151702850778783 cycloserine -0.364871808336199 -0.641108528312946 0.389343747332545 -0.521248386494047 -0.645240050590725 -0.18524784158981 -0.287802949985425 -0.548125518184584 -0.559461978459035 -0.652384581185965 -0.346221904551225 -0.566631818317608 -0.668232844808017 -0.677787672380599 -0.679858910067982 -0.634150080903465 -0.520618947139157 -0.502581834343706 -0.670784229596661 -0.249160814174304 -0.613366389220651 estriol 0 -0.567524049559263 0.119287731492135 -0.518785743830984 -0.573890353265196 -0.126275909270186 -0.134219266073084 -0.61747429314721 -0.558523621888867 -0.62335515255288 -0.395349020768263 -0.513984777895276 -0.603413100153018 -0.656025950100704 -0.659665772018142 -0.584367165746513 -0.148262973369944 -0.599739950481693 -0.694820710076897 -0.482856872021471 -0.555895703676166 meropenem -0.0928234920134915 -0.556806091720346 -0.271227547287211 -0.422116734591659 -0.507436267468379 -0.258442484670849 0 -0.579604865701013 -0.515205842238903 -0.335498026075747 -0.0625760577708463 -0.285602075455554 -0.534911645637062 -0.591248867916452 -0.467904663782756 -0.562732817909078 -0.3232155421939 -0.469625061703766 -0.691003187424226 -0.244632100631685 -0.428651402731815 dorzolamide -0.0740571916579034 -0.155690109661948 0.0634521730630152 -0.261607484970878 -0.49567467436269 0.0710789372473352 -0.236983412556209 -0.409823120144207 -0.211158946718508 -0.282427400422918 -0.26421602710284 -0.245793498372025 -0.253321620399744 -0.196739507216771 -0.192731052313106 -0.233083659474548 -0.312782837100943 -0.24828633559297 -0.419774485656593 -0.331617607863603 -0.220565831790084 piretanide 0.384766557958672 0.147375095659942 0.0373925769746915 0.0813936293762371 0.138388501430777 0.175522321599983 -0.0850972047532975 0.130549070929318 0.24118841112937 0.177721238710046 0.243450778434294 0.293927088382065 0.183119186658567 0.0978902403581127 0.28011211092701 0.166399910591826 0.0144176434336325 0.134763081213514 0.0564288725938409 0.0335657524643302 0.107787114929259 oxprenolol 0.114257861301911 -0.480440221393904 0.0236721965288944 -0.562566931898308 -0.435107990781487 -0.102424421898629 0.0265176205350061 -0.596570050038081 -0.55086880958996 -0.584053067447198 -0.32418538396733 -0.47949963665748 -0.598975444889002 -0.515525653602398 -0.621688924941629 -0.487239618272913 -0.437248877489283 -0.578171142823141 -0.713505869207515 -0.101703654983963 -0.313616208424686 tropine 0.325109107744382 0.221617499633477 -0.13130751942586 0.209084095044787 0.242735573274569 0 0.154279516143494 0.212907734108163 0.283765650657896 0.0752286138248938 0.174721619410634 0.219777020454801 0.270114369818237 0.264371870544987 0.240489907171586 0.266802780505136 0.0189027332159475 0.207448593509881 0.129384714384358 -0.00121027103839352 0.271739048984559 chloropyrazine 0.159933020784228 0.420257593588292 -0.0535438344879921 0.354899977528115 0.407335540172622 0.207759837931706 0.474585717807936 0.457181513075537 0.289922371484503 0.3500371474075 0.360253466302085 0.5614531255645 0.454922536580965 0.366187470323037 0.472571458181078 0.447048310994454 0.391950201532367 0.341038754782437 0.191755937746704 0.352346094736579 0.337051674561328 (-)-isoprenaline -0.184393281326419 0.0216443881229318 -0.242582481031377 -0.110611570743657 -0.215130273819772 -0.192410278422497 -0.0583502125169162 -0.211523001951776 0.101255081534414 -0.196649704348127 -0.038360039734539 0.0255886981720584 -0.0834382905693627 -0.110407423661512 -0.12372172747157 0.0382223376730624 -0.0447837072038342 0.0540641249526266 -0.273431496648477 0.0218569184963527 -0.0669411431258979 ramipril -0.178962374062209 -0.251357405193702 -0.3669141279473 -0.049444295615325 -0.122221698360956 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-0.0928181255338245 -0.26359485852574 -0.172052042968667 -0.32159796731685 -0.429270208702772 0.137962432750546 ondansetron -0.00720269762836212 0.364042768853163 -0.453825038934806 0.465136183120437 0.34427781164549 -0.126157719708832 -0.00880434165251238 0.321817713261191 0.536640968007046 0.423442327653778 0.334152923679199 0.406328575463647 0.463997160061566 0.350397200050849 0.338689720522832 0.392058934183465 0.554123498534722 0.341955707676112 0.342340798548605 0.427568526037499 0.231191678331754 thiethylperazine -0.0735243237538202 0.114801911800452 -0.29190488367563 -0.0673455306650156 0.00621838521305287 -0.0126017175430794 -0.323921770980659 -0.0222018800653157 0.0229044427022699 -0.0868353335558024 -0.255974204162191 -0.00070159068980627 -0.013631985212965 0.00903105134131943 -0.00658203643763039 0.0520284134510988 0.189129378203567 -0.0730857489301156 0.133674203415569 -0.0881518193336946 -0.105395569337244 benzylpenicillin 0 -0.34283838478407 0.158526291196221 -0.44626087566137 -0.298835261070221 0 -0.126103833023471 -0.492688685907242 -0.282281374818572 -0.290221890550479 -0.281839212998772 -0.147590276636355 -0.353988927490431 -0.367772202689545 -0.376651856227687 -0.213066624747056 -0.296156691773529 -0.206778658635822 -0.534719425895787 -0.152257188020113 -0.346618544363373 oxedrine -0.448515691468641 -0.0633464014633148 -0.325989283350304 -0.0780332236022258 -0.112916981111745 -0.251610986826634 -0.264729255256297 -0.103715186072978 0.0983248997328723 -0.0548157970500914 -0.125214987126548 -0.110666059124557 -0.212478607620892 -0.0500365770459318 -0.0247133435324395 -0.187948939205821 0.0322503104784611 0.0352149544841034 0.111160510726469 -0.0782236779007707 -0.292912135511078 kaempferol 0.0164336145416073 0.135424935529423 -0.337430623575429 0.22295330368972 -0.0214139863121091 0.112633685261408 -0.0676997569682161 0.0973809538491859 0.447639900613145 0.111456577822053 0.0673421901507891 0.296516961932251 0.10418643307639 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0.150033861066787 0.0835985087292496 0.00708688060045964 -0.00754805771928014 -0.14582149351162 -0.0700502026393391 -0.0764989059208194 0.0314035139388485 -0.0237112266475521 0.0192050727063755 -0.00211603085074279 -0.0996663105988213 0317956-0000 0.103917272701165 0.240389334248005 0.223553334684048 0.0153996508040027 0.121293874653083 0.172517258717778 0.253098410016635 0.156288397860521 -0.0199666743746382 0.236342309061589 0.191043331431312 0.167981155477074 0.250123915390039 0.111297854441208 0.163765664903739 0.00995999238165036 0.146064963759828 0.155120640968859 0.0190566014478844 0.213797162039402 0.0942578015312265 chlorambucil 0.073107574087335 -0.500058010432094 -0.154647534402129 -0.35434432045017 -0.306518700764007 -0.0224304069186807 0.102209534933818 -0.426163483660966 -0.226819425173729 -0.394373073961106 -0.304749902027569 -0.269015652173144 -0.477672344665772 -0.526843301649496 -0.580590728853447 -0.354306477783823 -0.121709698936565 -0.407524540873073 -0.561005670577102 -0.177376077304358 -0.279692151493767 levcycloserine 0.129026266232362 -0.576218206220637 -0.0214020154448424 -0.493556290004295 -0.280399754456815 0.0358253085046591 0.134591267851597 -0.419129439487908 -0.361050530332295 -0.508117927341056 -0.279361699139729 -0.386055621641185 -0.456492037530864 -0.597043157884886 -0.622614174219777 -0.535948395857006 -0.443037495368462 -0.518389265480017 -0.385991818860934 -0.114087176942163 -0.254273922192913 nialamide 0.00372407363093896 -0.53377014154371 -0.287215455110268 -0.49837608552704 -0.321687292711593 0.21738168932347 0.00830115746509355 -0.551383374513522 -0.373878129156976 -0.309081096067304 -0.29774627595532 -0.251468094375569 -0.319247238018517 -0.488629393776903 -0.475263862799464 -0.435377979280473 -0.334960477052839 -0.425884080920672 -0.588522653370462 -0.329966277197221 -0.247120184850202 quinethazone 0.12998241006899 -0.417545837498235 -0.243863325212491 -0.440632419746645 -0.271905415326876 -0.0885122206178763 0.268805820496685 -0.422922847819984 -0.421153676361414 -0.271079579549954 -0.161051810127285 -0.373272780613745 -0.406852767032151 -0.437135342510589 -0.543780317037316 -0.368261380127676 -0.19269264676562 -0.513635483298174 -0.562817764836963 -0.108329837422639 -0.249393263766319 santonin 0.12896965015818 -0.306602810939444 -0.284575296730769 -0.297331016744112 -0.19899087795111 0.107245756798546 0.140345069071776 -0.195786233576361 -0.233627106222995 -0.19317719281677 -0.113032198192215 -0.160282038106499 -0.257806325161208 -0.305234797085794 -0.317154105201563 -0.257850066749894 -0.21489181110135 -0.292259995782636 -0.358708691068196 0.0140756190995664 -0.317309296698134 Prestwick-1080 0.156402766814998 -0.165850158823289 -0.139119175588361 -0.249232547780704 -0.120491885113863 0.175240334770571 0.179447331119678 -0.142168618140878 -0.0691909501843862 -0.257733691848804 0.00739015595945577 -0.0824017922993225 -0.133370966852458 -0.193762772891302 -0.196006610521715 -0.126834111930678 -0.232639439327795 -0.276429493664692 -0.339685472300027 -0.159915939998466 -0.0981255029273538 homosalate 0.048681374949464 -0.256975684413675 -0.161911364466057 -0.297829140620257 0.0120941850640753 0.047997974398346 0.358597766278814 -0.108971808369606 -0.222895783285926 -0.358199150179514 -0.177010823101167 -0.0695290972813834 -0.105209397499866 -0.262729922025327 -0.303548602508651 -0.129410522029565 -0.166468356127468 -0.229076602934694 -0.314475693582168 -0.0138854994782077 -0.00203889790573386 Prestwick-1100 -0.244607232662085 -0.407655877785521 -0.14194944983526 -0.468171154233879 -0.241610831498162 0.0168938613825846 0 -0.271422038904982 -0.192690518845729 -0.214748289395197 -0.274121539434509 -0.167289390545258 -0.276432775692367 -0.416081786660813 -0.335368342795266 -0.365942003076465 -0.229638670436436 -0.384120156107603 -0.344452252330986 -0.301455451068487 -0.356294982247045 parbendazole -0.299061866587567 -0.349749847832867 0.425457675615694 -0.314977432865868 -0.372414084776108 -0.349063445180885 -0.225988703603413 -0.381559347587512 -0.186684064949005 -0.316071209120493 0.0260284811817569 -0.279300458132104 -0.323509438746971 -0.285525894695293 -0.224110364640156 -0.320675764121545 -0.378610893765938 -0.301455008779862 -0.356100956049276 -0.303661173011105 -0.161396460371546 ciclacillin -0.126738963668592 -0.0256372490163529 -0.294146404565643 -0.00363431102777667 -0.0113373479709491 0 0.337414334441844 0.10478972587397 0.123859871666252 0.0880372760845817 0.0119365375994608 0.186059637677525 0.00845253996770043 -0.0512016172449866 0.00186590073314413 0.0836268683691966 -0.188401429064818 -0.0458271678299513 -0.0149039299862382 0.0952382480185805 -0.145259715354015 2,6-dimethylpiperidine -0.0397950487132176 -0.404967645353961 -0.0884012588382242 -0.254105962571475 -0.293366518606872 -0.0216389005252464 0.0151654772228255 -0.204206047499383 -0.17461885717517 -0.330556014054662 -0.188809638578157 -0.124157605973385 -0.404447683733763 -0.29232740096311 -0.327078581679934 -0.395793178090461 -0.229362502093697 -0.243101128619777 -0.373978402491693 -0.156138201314883 -0.136765876595725 spiradoline 0.128437411879928 0.0737590559281342 -0.150026979720666 -0.0463513918826869 0.135753531641507 0.372152860219117 0.115774709626244 0.104388964622957 -0.0333127962766672 -0.117011346662029 -0.109698681500743 -0.0268527237830128 0.0834344065247864 -0.0303217000965129 0.0526599275087943 -0.00816247775656515 -0.131807240378472 0.083116022828135 -0.0527679321349072 -0.144987562507718 -0.0209469457175925 withaferin A -0.575557291609838 -0.488343400565516 0.140035023833372 -0.327024462436735 -0.35114472386077 0.112169514471921 -0.406781179974237 -0.257931294622828 -0.140111565644001 0 -0.376547909799019 -0.106998071824419 -0.525685969935635 -0.551957610923123 -0.622192107549006 -0.104052354346639 -0.223849467327957 -0.454282000718694 -0.506315053566968 -0.347460937770229 0.257714773557531 citalopram -0.120216008831411 0.121481005869403 0.0943579759261388 0.007062459588713 -0.0782060428380509 0.13497886373239 0.0389844167906847 0.0743170014068981 0.204360951687203 0.104303761369925 -0.0769352189802328 0.00911756658639096 0.0824588738293319 0.199651362822205 -0.0325744400403779 0.0997737196309717 -0.0399552429261623 0.0994363694728375 -0.0245848487959204 0.300413948965956 0.0633867383135397 paroxetine -0.0879487599318964 -0.0321167674745197 -0.0980025082600873 -0.155542847833986 -0.0414735672385375 -0.234871294059209 0.277444632680911 -0.0495628706088415 0.00889516033309933 -0.0833417001115486 -0.0166560740797701 -0.135549274050341 -0.0272476058011087 -0.0363130084932009 -0.0688175273714219 -0.0283653645041643 0 -0.128729707195291 -0.0757802278985916 0.0440098866692433 -0.0100032717618405 CP-320650-01 0.128568354213035 0.427334567385015 -0.296802532872469 0.326772598215383 0.372536057107901 0.518179898383427 0.0953560398283605 0.435434808493035 0.321821291644995 0.4206416032271 -0.000377488868140291 0.274548282492114 0.408833386907054 0.433274007026103 0.352286385415467 0.368163681651437 0.119516281754365 0.363519071992534 0.353249917813 0.0869400001095473 -0.000307600388009296 CP-690334-01 0.125520590616022 0.0596553766286806 -0.275006177894929 -0.130096210613099 0.0964909723945755 0.507162069817527 0.151840878118146 -0.0921953038420798 -0.130037825013723 -0.194455391530617 -0.115687382550831 -0.077051516259937 0.102889097728935 0.0509599040735138 -0.0701988999504861 -0.0547481135906793 -0.0887816049633804 0.010797803864433 -0.0119694036550932 -0.308687809048059 -0.259438129073625 PHA-00745360 0.0721394226538057 0.475183837022023 -0.219732922227265 0.31483249436316 0.436634839332091 0.472527494765693 0.251942386614809 0.503982398447518 0.418732951515283 0.437135336019863 0.135672249760178 0.409033163138937 0.462161792480934 0.47395813785785 0.336867003219286 0.475207488253628 0.38914259297999 0.480746707101446 0.462444653798799 0.178039428091483 0.243686149710665 rifabutin -0.303943285950983 -0.397158435890589 -0.00669734334073872 -0.685060558525925 -0.386258301903076 0 -0.328749623132663 -0.599491824807487 -0.524365750383113 -0.712886246885276 -0.452966354570461 -0.604989350683809 -0.476070451850246 -0.603562150082868 -0.541358470553113 -0.440101658218253 -0.669573265599158 -0.510445448277848 -0.472081961549654 -0.689180028197072 -0.159969904157089 alcuronium chloride -0.245576284537522 -0.519312631460151 0.166055630485648 -0.506171401301375 -0.583506419991127 0.255789839291026 -0.27285188594945 -0.536248342124468 0.0441573827600084 -0.517775939277284 -0.202357635384932 -0.495340544359438 -0.523669733419618 -0.49841484649666 -0.522244642042125 -0.503846099972708 -0.210082385793248 -0.53917791664844 -0.607084291218381 -0.216573744140585 0 clobetasol -0.612502420867753 -0.53872067346856 0.262907681818671 -0.456110707769227 -0.564259239160086 -0.360593674276118 -0.361472688848692 -0.573702594898924 -0.497068407403062 -0.408464698828794 -0.414456319935632 -0.518465344152271 -0.585511138198045 -0.549796096874872 -0.546937570102855 -0.550419805517673 -0.337343175313068 -0.563583448398611 -0.412843931291792 -0.477004017895987 -0.295213662488987 phenoxybenzamine -0.646966865016106 -0.664406915996493 0.645081103046499 -0.597098851873178 -0.69440491700862 -0.714231870503053 0 -0.783143240458472 -0.474821621295168 -0.550417130645669 -0.627951273388361 -0.588457347376259 -0.704605791542908 -0.707784901142828 -0.76410212203746 -0.641327614433368 0 -0.727025844035139 -0.736154681335194 0 -0.41070622002234 timolol 0.117127911145185 0.631839960916775 -0.0116733074988219 0.545402130901022 0.65053108688802 0.59159243331063 0.27586880811964 0.657757971296929 0.475907781576147 0.608077927418773 0.24679924109598 0.573220034914348 0.663230238122704 0.687631875008383 0.660519860369524 0.628873575593884 0.383528191584262 0.638577432323198 0.664768584202295 0.108424824288056 0.405810741016746 daunorubicin -0.664120655910988 -0.495264872283658 0.273733690451661 -0.271838487946619 -0.715590315371479 -0.501357027310725 -0.559189590872702 -0.72828757629081 -0.567221921007545 -0.6430440202561 -0.399347857176928 -0.614332215652948 -0.68067308136597 -0.629297754895741 -0.660273231564096 -0.447459327608376 -0.197347343874803 -0.469363282898122 -0.444443965599384 -0.25157141538908 -0.341933438597397 nomegestrol 0.0276511248667416 0.269766326035524 0 0.418637508326167 0.284510964176434 0.0273080780898448 -0.182957419935244 0.27789667428588 0.212678388655008 0.451846365259115 0.0452064807991893 0.471945171044697 0.2863275816699 0.465153005130424 0.281016175433837 0.292082249851469 0.407586823256927 0.357819940770684 0.465588718368289 0.0314300796907127 0.3428357607954 ticarcillin 0.18806025496248 -0.0626287115854661 -0.13755603273324 -0.126903564884712 -0.380967234030369 0 -0.280915983928386 -0.206291863338939 -0.237755602479798 -0.349642706652916 -0.15178307366627 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-0.475971601454959 -0.592638832485543 -0.534217535515842 -0.675673414354651 -0.663052074187597 -0.619751519992313 -0.717102914972159 -0.683734084791037 -0.63038293128163 -0.735611543563427 0 lomustine 0.140635588440408 -0.274640480080053 0.131915833784155 0.1321367766207 -0.337214138154006 0 0 -0.138247032086561 -0.128779249678517 0 -0.109661417394029 0.142418510641259 0.00169265236068269 -0.357122538255287 -0.349301369577243 0 0.146405905447619 -0.150657439174945 -0.0209654797195021 0.127585103018209 0.290892153538821 PHA-00846566E 0.0263090627447205 -0.172648465611713 -0.150124335969607 0.0491924304271986 -0.246669757613807 -0.00842603802404969 0.227423521156869 -0.211869210280975 -0.35967515068077 -0.0777234368644814 0.0173531701869206 -0.146846445530686 -0.123061441284735 -0.178409839568944 -0.120121915645513 -0.188103799124932 -0.0132833979380298 -0.0162978352218969 -0.189239363068757 0.143268917285617 -0.0308857086000892 AH-6809 -0.287091220744844 -0.205413180303229 -0.360327670900029 -0.192848894882856 -0.234468419786271 0.216346748437057 0.30525718947768 -0.0335857621014174 0 -0.200399391212985 0 0.26604037061383 -0.454215220141522 -0.267550274902838 -0.226357878272206 0.0121679301817122 0 0.029160178320031 -0.285834710676375 0.0487571262411555 0 alsterpaullone -0.387864493080506 -0.576856327859396 0.481539476361821 -0.204626840753354 -0.518374257500192 -0.53808124862021 -0.436167706975623 -0.544307710824255 -0.544760332670568 -0.725172893852717 -0.558501338682907 -0.626863483159856 -0.486386958716716 -0.64540720133104 -0.745988922237166 -0.213694065942165 -0.275404987768807 -0.533308638740523 -0.22063418568706 -0.579521734037451 -0.557853715101522 0316684-0000 -0.11739423709686 0.132106219407263 -0.32070429302977 0.129320452818252 -0.00176728877659621 0 0 0.0425236559280485 -0.171497700879796 0.0412015648389949 0.199544534120676 0.0593035803655707 0.130622583688746 0.032615609960112 0.0357074152501528 0.0352484453785938 0.380855524638403 0.167632504907915 0.116188522894633 0 0.124427218001489 thapsigargin 0.197914885674281 0.563787966716738 0 0.457399115859755 0.258993852657079 0.280557584169544 0 0 0 0.161709546162643 -0.0833876233161826 0 0.205861246431344 -0.00248354297509808 0 0.406990750120386 0.532376067710674 0.228604584893058 0.401668723057726 0.179901275932725 0.381658912831428 SC-19220 -0.330934889496999 -0.227769974224907 0 -0.12179571315842 -0.201421778091201 -0.384972017953257 -0.348843082478603 -0.27972439766057 -0.20061627714008 -0.102045266163376 0.0297822543609959 -0.204313886168853 -0.110462344225953 -0.0910807811247324 0.0475862333950872 -0.209740825675996 -0.226532027796593 -0.155642448344986 -0.242879028849299 -0.0055509768902007 -0.082555380593535 GW-8510 -0.297450342106932 -0.551105431285229 0.423637600007486 0 -0.694587262898686 0 -0.523128349343133 -0.737760587822266 -0.570017493322456 -0.730668011961118 -0.580155639002885 -0.663178658375197 -0.686068931988016 -0.698995425593953 -0.753872980192817 -0.13222378671819 -0.317582587852934 -0.398991076071582 -0.482293652492739 -0.593465902556335 -0.542876449603444 MG-262 -0.502632481972852 -0.420572610029556 0.521419365852718 0.172501780788515 -0.368505292744702 0 -0.178169993434648 0 -0.544608783782207 0 -0.172533704640638 -0.168304176425957 -0.189095891987365 -0.718528090453856 -0.761300159230548 -0.446596610513105 -0.354933325858766 -0.284141805719834 -0.194667560221367 -0.435429319901352 0.465894473524123 0198306-0000 -0.0369133001146272 -0.532617207224445 0.0871884245387344 -0.395882644026006 -0.313755365726022 0.0734224355462473 -0.1203116233507 -0.455116006961706 -0.264738301797741 -0.292055164188413 -0.0971839565552055 -0.414382393941186 -0.452424549869952 -0.201061616517738 -0.457529104803271 -0.375874675397434 -0.266955129442321 -0.294186226105776 -0.45558824318065 -0.109016768222512 -0.404169830236388 AR-A014418 0 -0.156562874059988 -0.169085532869101 0.0501805702400462 0.0320620818478906 0 0.351994766942326 0.211441431526291 -0.0937419717042727 0.0891117867439395 0.0867925580976535 0.119876658999468 -0.115289277131865 0.0889952114412921 -0.136244258258253 -0.111164153496364 0.284738062467543 -0.105895276558853 -0.10009695815036 0.244486500688437 0.207244752444771 CAY-10397 -0.187724239772769 -0.0685269818978692 -0.236349199901651 -0.215661472875439 -0.260478626377029 -0.0824008541611826 0.194525864168141 -0.250552382411976 -0.351511732552574 -0.0279536298947692 -0.0655456371645919 -0.0231334959847978 -0.0500970672462942 -0.0451875555493005 -0.216505683745651 -0.230082727962244 -0.185404642683853 -0.0650908297236697 -0.224356651066822 -0.333106389629667 -0.171282996085785 PHA-00816795 0 -0.0264270818784343 -0.265978503001696 -0.0664815706590793 -0.0316545857017287 0.155752019828418 0 -0.0780177048792348 -0.246858354137695 -0.277824605320841 -0.207192860463269 -0.0286600046592011 -0.0612751837542371 -0.115000167432536 -0.400352832095475 -0.096663780046038 -0.0135839454307463 -0.0771225407282152 -0.119005958448002 -0.575051241810287 0.275608935192488 MS-275 0 -0.645192159407563 0 -0.644210327553639 -0.607041441552809 0 -0.906065777075306 -0.644896923921222 -0.606470052951207 -0.8806511222939 -0.750984950969814 -0.7646842720033 -0.669274912183744 -0.806851951975833 -0.832976486941893 -0.344263004834435 -0.303285264596275 -0.354665489117214 -0.65974639581824 -0.858334447368466 -0.577417530701911 CP-319743 -0.224524916974943 0.0190817323853605 0.0843236938191426 0.149019097768853 0.01053188438266 0.221511111377188 -0.112902953908612 -0.129094978910346 0.0384374281906359 -0.0455709121591479 -0.0690221852531668 -0.10639363539304 -0.130571519301066 -0.0529025622138355 -0.123041958282191 -0.0997378011561389 0.219960315498087 0.14168444117166 -0.114179515125712 0.149589559678832 -0.0842310760982853 semustine -0.405369040338674 -0.229900990535018 0.121014905667331 0.0235377408610594 -0.023698640679163 -0.170374791708878 -0.14673545316672 0 0 -0.110230778874921 0 0 -0.270508913956075 -0.28849725299244 -0.255041680703763 -0.133165131267707 -0.0908075138248216 -0.28055146456856 -0.230961528592941 -0.109053618929569 0 BCB000040 -0.14027216096868 0.352639711829871 0.207152054534764 0.303219624991255 0.188292333061382 -0.126286314590278 -0.195182338426215 0.212796703664349 0.245868423913509 0.352979440865748 0.27361862118651 0.228053951495506 0.253254329879044 0.276363346700333 0.289653106226708 0.295715612531561 0.259140761153627 0.277018455648173 0.295271233115132 0.366108213607148 0.196995389606546 15(S)-15-methylprostaglandin E2 -0.183141072552003 -0.139822176495189 -0.157014127311047 0.172918846906193 0.00388029594066361 -0.30602004077103 -0.166564894979549 -0.0520965370317 0.0433470101408574 -0.192176975119819 0.18457199715056 -0.0347355762985917 -0.15662243719195 -0.0853332512237191 -0.18826264813526 0.0912061849292651 0.167786630064673 -0.0414244805693775 -0.132399383204064 -0.0345860006091674 0.18042000790436 suramin sodium -0.285146392097208 0.144754689182771 -0.045620982269571 0.157897387696207 -0.00223158464167168 0 0.199399438611626 0.118176165243766 0.173701979626828 -0.0263658571150537 0.261344002704703 0.146530686510453 0.00247967230327258 0.021901546911306 0.154361204192696 0.0235294119618469 0.0770692776591961 0.126581677032912 0.170804175171259 0.0363962029150499 0.0570631845098994 CP-944629 -0.487523318151298 0.0202104154223449 -0.0640726053489869 0.108404125061331 -0.233647785040808 0.0402523160681309 -0.0696788668976855 -0.379317143774362 0.0239638313001379 -0.11539533805331 0.156563989064496 -0.120844105168598 -0.101929881318681 0.041323880707702 -0.0978156240642135 0.150095390711663 0.138089683903932 0.0292419165880686 0.0256628766370042 0.0331875031050453 -0.257156815959086 irinotecan -0.249704690905489 -0.185540512403773 0.152192597942267 -0.195448532984628 -0.632670156710326 -0.702628935099355 0 -0.570003456335967 -0.186627468472854 -0.221103173188783 -0.348401527349526 -0.365066351380481 -0.399192573892851 -0.351171012551578 -0.216749805551988 -0.0187041490027807 0.401846888794614 -0.015372504493035 -0.209649112929793 0.0693093298090941 -0.151541831152771 meteneprost -0.144166994128931 0.511653762404786 -0.150658949097183 0.510092473665928 0.358557435635555 -0.291146560667992 0.170180005001057 0.490266961064286 0.474402996941166 0.46139843395476 0.507284152291569 0.497384268081989 0.49298510903042 0.60045473402035 0.615751253859469 0.636570088534066 0.316092196548046 0.593025183584664 0.636905259838845 0.195869322015504 0.568648227054313 16-phenyltetranorprostaglandin E2 0.239396589062652 0.222282049283231 0.143077871133251 0.0972702700628145 0.070813240694375 -0.224485310381032 -0.117785302981796 -0.0272850534070239 0.198437769167348 0.246601677988103 0.125721653490382 0.0747847101456996 0.166199740287421 0.0957054564419789 0.17286850811108 0.208610411685656 0.336999162059428 0.100536782237815 0.214142254975897 0.107517179589221 -0.0438021703145426 CP-863187 -0.266584300417419 0.354091103968742 0 0.411466085836918 0.166232010716137 0.16215405489319 -0.0333081678099104 0.311547867065159 0.437400747668865 0.221802729343745 0.230535826496574 0.206275236550472 0.356446973099308 0.367864861441458 0.406564252287478 0.342656100642391 0.445915247126288 0.394539154783733 0.419442867606967 0.494217200031001 0.167653288129079 BCB000039 0 -0.268994824907272 0.124368590626261 -0.268649607672289 -0.204355564465162 -0.085034113208482 0 -0.268379460395394 0.0164176032898253 -0.12690251231536 -0.126594864098745 -0.195143520855144 -0.268734052348938 -0.284952736906026 -0.275734136737795 -0.24851866682193 0 -0.233388628477268 -0.243461098330191 0.0117142506628071 -0.194806761673143 IC-86621 -0.103609148757244 0.0513196079804546 0.131225708853211 0.161991378994148 0.234455253278709 -0.018926644682183 0 0.283150000778907 0.1435044585877 0.115666619266655 0.0779827221068389 0.16730613266908 0.0582740966916798 0.163246123143441 0.233144377496973 0.176278469276537 0.00816006279470283 0.131056893839993 0.0933296412395855 -0.113461591873597 0.0364275543368773 11-deoxy-16,16-dimethylprostaglandin E2 -0.113268691733354 -0.100695454662873 0 -0.183072884464604 -0.206448712610945 -0.307853464291846 -0.132148109714464 -0.173356908684963 -0.262903200864238 -0.109812978935747 -0.203885701279177 -0.200131065044879 -0.338283128122964 -0.463775612379977 -0.252104968293812 -0.185348277818132 -0.0426954345311377 -0.168886885080877 -0.139148105258622 -0.0899227350723288 -0.158032873057831 CP-645525-01 -0.545445489074104 -0.539926417087777 0.635974884850281 -0.471125827542803 -0.526077479907278 0 -0.532259811512637 -0.534255778361416 -0.398544765661541 -0.578660096717586 -0.445287669609003 -0.313238131527986 -0.589439287697629 -0.572745916804815 -0.659697879706462 -0.527657300028362 -0.443958971615467 -0.54208137289207 -0.548663618024598 -0.455423551214057 -0.587261823479982 BCB000038 0 -0.197847948027562 0.126574622001924 -0.151914698308436 -0.301541931700784 -0.26916044515585 0 -0.342644218013984 -0.270568952676874 -0.0539516817925179 -0.00271156805297436 -0.06944392992877 -0.293494764099477 -0.217132595430226 -0.0414898506494567 -0.191352243802127 -0.0882675815371795 -0.261548371604626 -0.180368444035598 -0.167655498494633 -0.272703730837514 vinblastine -0.18877021609594 0.476124556155733 0.375610200736477 0.689537478341216 0.44338301458106 -0.200383121970838 0 0.664822001114324 0.392988419129103 0.44591148587341 0.389750694382592 0.458121180396062 0.544635620579015 0.674531759875399 0.52402913002426 0.64701942775653 0.228123319859675 0.634345775328088 0.743309137825022 0 0.237312169728746