Nucleotide A subunit of DNA or RNA consisting of a nitrogenous base (purine in adenine and guanine, pyrimidine in thymine, or cytosine for DNA and uracil cytosine for RNA), a phosphate molecule, and a sugar molecule (deoxyribose in DNA and ribose in RNA). Depending on the sugar the nucleotides are called deoxyribonucleotides or ribonucleotides. Thousands of nucleotides are linked to form a DNA or RNA molecule. See also base pair.