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Current funding | Past funding

 

Projects

We are grateful to our sponsors for funding and supporting our various research projects

 

Current Funding

 

  • Ontario Research Fund: Protein network analysis of cancer surfaceome - from interactions to drugs
    PI: I. Stagljar and I. Jurisica
    2016-2020

  • CCSRI: A novel model of human brain metastasis from lung cancer: Discovering genes that regulate brain metastasis
    PI: Sheila Singh
    2016-2019

  • Medicine by Design: Pathways to enhance the clinical utility of hematopoietic stem cell transplantation
    PI: J. Dick
    2016-2019

  • Genome Canada: The Mammalian Membrane Two-Hybrid (MaMTH) Assay - an Advanced Proteomics Technology for Biomedical Research
    PI: I. Stagljar and I. Jurisica
    2016-2019

  • Krembil Foundation: The Osteoarthritis Data Integration Platform (OADIP): Identifying and mapping genomic markers of osteoarthritis
    PI: I. Jurisica and C. Veillette
    2016-2018

  • NSERC: Developing novel heuristic methods for integrative computational biology
    PI: I. Jurisica
    2013-2018

  • DOD: Optimizing Early-Phase Translational Ovarian Cancer Clinical Trials with Integrative Computational Biology
    PI: A. Oza and I. Jurisica
    2012-2016

    CRC-CFI: Integrative cancer informatics
    PI: I. Jurisica
    2011-2018

 

 

Past Funding

PI: MC Hung

2010-2015

 

  • ORF-RE: Integrated Molecular Pathology of Targeted Cancer Therapy in Lung Cancer (IMP4-Lung Cancer)
    PI: M. Tsao, I. Jurisica
    Co-applicants: F. Shepherd, G. Liu, T. Kislinger, M. Moran
    April 2009-2015

  • CIHR: Diagnostic and prognostic biomarkers for epithelial ovarian cancer
    PI: I. Jurisica, A. Oza
    Co-applicants: T. Kislinger, T. Colgan, A. Jurisicova
    June 2009-2014

  • NIH: Development of an expert crystallization knowledge system

PI: E Snell

2009-2014

 

  • McLaughlin Centre: Cancer prevention and treatment by molecular epidemiology
    PI: I. Jurisica
    2013/14

  • CIHR: The interactome of the human G-protein coupled receptors
    PI: I. Stagljar
    Co-applicants: Bouvier, Michel, Jurisica, Igor
    2011-2013

    NSERC: Techna 2012: Information and Communication Technologies for Health

    PI: I. Jurisica
    2012

  • NSERC: Scalable intelligent systems for integrative analyses in computational biology
    PI: I. Jurisica
    2012-2013

  • CFI LOF: Integrative computational biology for cancer genomics
    PI: I. Jurisica
    2011

  • IBM International Foundation: Help Conquer Cancer
    PI: I. Jurisica
    2011

  • NSERC Discovery Grants: Integrative Computational Biology
    PI: I. Jurisica
    April 1, 2007-March 31 2012

  • CIHR Catalyst grant: Tools for efficient and effective network-based prediction of diagnostic and prognostic cancer signatures
    PI: I. Jurisica;
    Co-applicants. Drs. M.S.Tsao and I. Stagljar
    November 1, 2009-October 31, 2010

  • CIHR: Maternal lethal effect and human infertility
    PI: A. Jurisicova
    Co-applicants: I. Jurisica, E. Greenblat
    July 2007—July 2010

  • Canada Foundation for Innovation/Ontario Research Fund: Comprehensive Systems Biology Approach to Profiling and Modeling of Cancer. A collaborative infrastructure for integrated translational research.
    PI: I. Jurisica
    Principal users: Attisano, L., Bremner, R., Brown, T., Jurisica, I., Kislinger, T., Penn, L., Rottapel, R., Shaw, P., Tsao, M., Wrana, J.
    2007

  • Canada Foundation for Innovation CRC/CFI/ORF Infrastructure – Integrative Computational Biology
    PI: I. Jurisica
    November 1, 2006 - October 31, 2011

  • NIH - the Center for High Throughput Structural Biology (U54 GM074899-01)
    PI: G. DeTitta, Co-PIs: Mark Dumont, Mark Sullivan, Eric Phizicky, Ethan Merritt, Sol Gruner, Igor Jurisica, Mike Soltis, Mike Malkowski, Joe &nb sp;   Luft, Eddie Snell, Keith Hodgson.
    Funded: July 1, 2005-2010.

  • Genome Canada – The Dynactome: Mapping Spatio-Temporal Dynamic Systems in Humans
    PI: T. Pawson, J. Wrana, S. Li, I. Jurisica, J. Dennis
    (January, 2006 – 2009)

  • OICR: Identification and characterization of genetic alterations at the stromal-epithelial interface in prostate cancer.
    PI: N. Fleshner; coPIs, T. Brown, S. Done, I. Jurisica, J. Sweet
    May 2007-2010

  • NSERC Strategic Grant: Intelligent monitoring, diagnosis, and rehabilitation of stroke patients.
    PI: J. Glasgow, I. Jurisica, S. Scott
    October 2006-2009

  • CIHR - Defining the canonical and non-canonical WNT signaling pathways
    PI: Attisano; I. Jurisica
    (July, 2005-2008)

  • CIHR - Endoglin, ALK-1 and BMPRII networks: Role in vascular disorders
    PI: M. Letarte; I. Jurisica; J. Wrana
    (July, 2005-2010)

  • CIHR - Myometrial programming: A new concept underlying the control of myometrial contractility during pregnancy
    PI: S. Lye; I. Jurisica; B. Langille
    (July, 2005-2010)

  • CIHR - Functional characterization of androgen-altered genes with a putative role during early events in ovarian carcinogenesis.
    PI: T. Brown, Co-PIs: I. Jurisica, P. Shaw, M. Letarte
    June 2005 – June 2009

  • CIHR – The next generation of gene transfer therapy for human nasopharyngeal cancer.
    PI: Fei-Fei Liu, Co-PIs: I. Jurisica, R. M. Reilly
    2004-2008

  • National Cancer Institute of Canada – Novel Molecular Prognostic Markers and Potential Therapeutic Targets in Non-Small Cell Lung Cancer (# 015184)
    PI: M-S Tsao; Co-PIs: I. Jurisica, W. Lam, M. Johndston, S. Der (UT), M. Pintilie, D. Wigle, F. Shepherd; Additional authors: C.-Q. Zhu, B.P. Coe, J. Liu
    2003-2008

  • DOD US Army – Integrated computational biology approach to marker selection for early detection and treatment of epithelial ovarian cancer. # OC040038
    PI: I. Jurisica, Co-applicants: T. Brown, A. Oza, P. Shaw, J. Wrana
    November 15, 2004- November 15, 2007.

  • NSERC Research Grant - Decision Support for Biomedical Domains
    I. Jurisica
    April 2002- March 2007

  • Ontario Cancer Research Network – Genomic and proteomic biomarkers of response to treatment with small molecule epidermal growth factor receptor inhibitors in non-small cell lung cancer; OCRN 03—APR-0324
    PI: M-S Tsao, Co-PIs: I. Jurisica, F. Blackhall, W. Newman, F. Shepherd, L. K. Seymour, M. Pintilie,
    September 2003- September 2006

  • NIH - Northeast Structural Genomics Consortium 2- Structural Genomics of Eukaryotic Model Organisms
    PI: Gaetano Montelione, Co-PIs: Arrowsmith, Cheryl, Anderson, DeTitta, George, Edwards, Aled, Gerstein, Mark, Hendrickson, Wayne, Honig, Barry, Hunt, John, Jurisica, Igor, Kennedy, Michael A, Regan, Lynne, Rost, Burkhard, Szyperski, Thomas, Tong, Liang
    Funded: July 1, 2005- July 1, 2006

  • GlaxoSmithKline – An integrated computational approach to identify important yeast proteins
    PI: I. Jurisica
    November 1, 2004-2005.

  • IBM SUR grant – Life Sciences Discovery Centre
    PI: I. Jurisica
    May 2005

  • IRIS - Intelligent Computational Methods for the Analysis of Gene Expression Profiles
    1/2002-2005
    PI: I. Jurisica, Co-PIs: J. Glasgow, R. Ng, H. Hoos

  • NIH - Northeast Structural Genomics Consortium - Structural Genomics of Eukaryotic Model Organisms
    (October 1, 2000 - August 31, 2005)
    PI: Gaetano Montelione, Co-PIs: Arrowsmith, Cheryl, Anderson, DeTitta, George, Edwards, Aled, Gerstein, Mark, Hendrickson, Wayne, Honig, Barry, Hunt, John, Jurisica, Igor, Kennedy, Michael A, Regan, Lynne, Rost, Burkhard, Szyperski, Thomas, Tong, Liang

  • IBM SUR Grant - Integrated computational biology.
    PI: I. Jurisica
    5/2003.

  • NSERC Strategic Grant, 1999-2003 - Knowledge Management and Decision Support for Crystal Growth
    J. Glasgow, I. Jurisica, S. Fortier
    Industry collaborators: Evan Steeg of Molecular Mining Corporation; IBM Canada, Centre for Advanced Studies

  • IBM UPP Grant - Data mining, visualization and interpretation of high-throughput biological data
    PI: I. Jurisica
    9/2002

  • IBM UPP Grant - Knowledge Management in Biological Domains
    PI: I. Jurisica
    9/2001

  • IBM UPP Grant - Protein Crystallization Knowledge Management
    PI: I. Jurisica
    9/2000

  • IBM SUR Grant - Decision-Support System for Crystallization Experiment Design
    PI: I. Jurisica
    12/1999.

  • NSERC Research Grant - Decision Support for Biomedical Domains
    3/1998-3/2002
    PI: I. Jurisica

  • NSERC Equipment Grant - Molecular Scene Analysis and Macromolecular Crystallization
    April 2000
    J. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto

  • CITO Research Grant - Knowledge Discovery for Crystal Growth
    April 1 2000 - March 31 2002
    J. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto

  • NSERC Equipment Grant - Computational Techniques for Bioinformatics
    J. Glasgow, S. Fortier - Queen's U, I. Jurisica - U of Toronto

  • CITO Research Grant - CBR: Knowledge Management and Applications
    April 1 1998 - March 31 2000
    J. Glasgow, S. Fortier - Queen's U, N. Cercone - U Waterloo, S. Matwin, R. Holte - Uof Ottawa, I. Jurisica - U of Toronto